Development and In Vitro Characterization of Microemulsions of Isotretinoin
There has been increased interest during recent years in the use of topical vehicles that may modify drug penetration into the skin1 .The most difficult aspect in skin delivery of drugs is to overcome the barrier of stratum corneum. Various strategies have been employed to achieve delivery of drugs into skin. Among these strategies, microemulsions have been suggested to serve as efficient promoters of drug localization to skin2-4.
ACTA PHARMACEUTICA SCIENCIA Dergisi 52/2/4. Sayısı İçin Tıklayınız.