Geri
AKADEMİK

(Liste, ünvan ve isme göre alfabetik olarak sıralanmıştır.)

Kurum İçi Görevlendirme

text
Adı Soyadı Prof.Dr. Lütfü HANOĞLU
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Prof.Dr. Gürkan ÖZTÜRK
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Hacettepe Üniversitesi 1993 King's College London

Daha Önce Görev Yaptığı Yerler

Yüzüncü Yıl Üniversitesi

Araştırma Alanları

Nörodejeneratif ve nörorejeneratif süreçlerde etkin olan moleküler ve hücresel mekanizmaların anlaşılmasında hücre kültürü ve hayvan modelleriyle araştırmalar yapmaktadır. Bir başka uzmanlık alanı ileri mikroskopik görüntüleme ve manipülasyon teknikleridir.

Seçili Yayınları / Tüm Yayınları

Aydin, M.S., Yigit, E.N., Vatandaslar, E., Erdogan, E. & Ozturk, G. (2018) Transfer and Integration of Breast Milk Stem Cells to the Brain of Suckling Pups. Sci Rep, 8, 14289.
Aysit-Altuncu, N., Ulusoy, C., Ozturk, G. & Tuzun, E. (2018) Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study. Neuroreport, 29, 932-938.
Bal, R., Ozturk, G., Etem, E.O., Him, A., Cengiz, N., Kuloglu, T., Tuzcu, M., Yildirim, C. & Tektemur, A. (2018) Modulation of Excitability of Stellate Neurons in the Ventral Cochlear Nucleus of Mice by ATP-Sensitive Potassium Channels. J Membr Biol, 251, 163-178.
Demircan, T., Ovezmyradov, G., Yildirim, B., Keskin, I., Ilhan, A.E., Fescioglu, E.C., Ozturk, G. & Yildirim, S. (2018) Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota. Sci Rep, 8, 10974.
Kuter, N., Aysit-Altuncu, N., Ozturk, G. & Ozek, E. (2018) The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in vitro. Neonatology, 113, 360-365.
Caglayan, B., Caglayan, A.B., Beker, M.C., Yalcin, E., Beker, M., Kelestemur, T., Sertel, E., Ozturk, G., Kilic, U., Sahin, F. & Kilic, E. (2017) Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice. Experimental neurology, 296, 23-31.
Demircan, T., Keskin, I., Dumlu, S.N., Ayturk, N., Avsaroglu, M.E., Akgun, E., Ozturk, G. & Baykal, A.T. (2017) Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database. Proteomics, 17.
Shahbazi, R., Ozcicek, I., Ozturk, G. & Ulubayram, K. (2017) Functionalized gold nanoparticles manifested as potent carriers for nucleolar targeting. Nanotechnology, 28, 025103.
Demircan, T., Ilhan, A.E., Ayturk, N., Yildirim, B., Ozturk, G. & Keskin, I. (2016) A histological atlas of the tissues and organs of neotenic and metamorphosed axolotl. Acta Histochem, 118, 746-759.
Kilic, E., Reitmeir, R., Kilic, U., Caglayan, A.B., Beker, M.C., Kelestemur, T., Ethemoglu, M.S., Ozturk, G. & Hermann, D.M. (2014) HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia. Front Cell Neurosci, 8, 422.
Bektas, S. & Ozturk, G. (2013) Enhancement of cultured adult motor neuron survival with cold pre-incubation. Neurosci Lett, 533, 23-27.
Ozturk, G., Cengiz, N., Erdogan, E., Him, A., Oguz, E.K., Yenidunya, E. & Aysit, N. (2013) Two distinct types of dying back axonal degeneration in vitro. Neuropathol Appl Neurobiol, 39, 362-376.
Cengiz, N., Ozturk, G., Erdogan, E., Him, A. & Oguz, E.K. (2012) Consequences of neurite transection in vitro. J Neurotrauma, 29, 2465-2474.
Demir, O., Aysit, N., Onder, Z., Turkel, N., Ozturk, G., Sharrocks, A.D. & Kurnaz, I.A. (2011) ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target. Biochimica et biophysica acta, 1812, 652-662.

text
Adı Soyadı Prof.Dr. Ahmet Zeki ŞENGİL
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Nozokomial infeksiyonlar, hepaptitis serolojisi, paramagnetic substanslar ve immun modulasyon, resistan tuberculoz ve immunite, nanopartiküller ve antimikrobiyal aktivity,

Seçili Yayınları / Tüm Yayınları

Sengil AZ, Akkaya H, Gonenc M, Gonenc D, Ozkan D. Species composition and monthly distribution of mosquito (Culicidae) larvae in the Istanbul metropolitan area, Turkey. Int J Biol Med Res. 2011; 2(1): 415-424

Valério P, Góes AM, Karacayli U, Gunduz O, Salman S, Sengil AZ, Yilmaz S, Agathopoulos S, Oktar FN. Influence of boroxide bioactive bioglasses (BBB) on osteoblast viability. RMN. Jorge, SM. Santos, JMRS. Tavares, MAP. Vaz and JCR Capos (Eds.). Biodental Engineering, CRC Press, London, 2009, pp 99-103

Karacayli U, Gunduz O, Salman S, Ozyegin LS, Sengil AZ, Agathopoulos S, Oktar FN. ‘’Effect of sintering temperature on mechanical and microstructural properties of zeolite (clinoptilolite) reinforced bovine hydroxyapatite (BHA) composites’’ . RMN. Jorge, SM. Santos, JMRS. Tavares, MAP. Vaz and JCR Capos (Eds.). Biodental Engineering, CRC Press, London, 2009, pp 105-108

text
Adı Soyadı Prof.Dr. Türkan YİĞİTBAŞI
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Eğe Üniversitesi 1988 Erciyes Üniversitesi Tıbbi Biyokimya

Daha Önce Görev Yaptığı Yerler

Erciyes Üniversitesi,Kayseri Devlet Hastanesi,Analiz Tanı Merkezi,Baylor College of Medicine,İzmir Bölge Hıfzısıhha Enstitüsü,İzmir Katip Çelebi Atatürk Eğitim ve Araştırma Hastanesi

Araştırma Alanları

Üreme ve Obesite Biyokimyası,Çoklu Yöntemlerin Klinik Uygulamaları,Oksijen Radikalleri,Klinik biyokimya

Seçili Yayınları / Tüm Yayınları



text
Adı Soyadı Prof.Dr. Bayram Ufuk ŞAKUL
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Nöroanatomi, Hafıza ve Öğrenme, Columna vertebralis, Kalp, Karaciğer mimarisi, Paranasal sinüsler, Cone-Beam Tomografi

Seçili Yayınları / Tüm Yayınları

KİTAPLAR

1. Şakul, U.: Baş ve Boynun Topografik Anatomisi. Ankara Üniversitesi Basımevi, 1999. (ISBN 975-94242-0-7)
2. Şakul, U.: TUS için Anatomi. Ankara Üniversitesi Basımevi, 2001. (ISBN 975-94242-1-5)
3. Şakul, U.: (Bölüm Yazarlığı) Wolf-Heidegger’in İnsan Anatomisi Atlası, Güneş Kitabevi Ltd. Şti. 2001. (ISBN 975-8531-13-1)
4. Şakul, U.: (Bölüm Yazarlığı) Korrelatif Nöroanatomi, Nobel Tıp Kitapevleri, 2002. (ISBN 975-420-216-6)
5. Şakul, U.: (Bölüm Yazarlığı) Göğüs Cerrahisi, Sim Matbaacılık Ltd.Şti, 2003. (ISBN 975-92200-0-8)
6. Şakul, U.: (Bölüm Yazarlığı) Netter İnsan Anatomi Atlası, 3. baskı, Nobel Tıp Kitapevleri, 2005. (ISBN 1-929007-11-6)
7. Şakul, B.U.: (Bölüm Yazarlığı) Temel Klinik Anatomi, 2. Baskı, Güneş Kitapevi, 2006. (ISBN 975-277-074-6)
8. Şakul, U.: Anatomi. Melike Ofset Basımevi, 2007. (ISBN 978-9424-22-0)
9. Şakul, U., Bilecenoğlu, B. : (Bölüm Yazarlığı) Pelvis ve Perine Anatomisi, Prostat Hastalıkları Kitabı, Güneş Tıp Kitapevleri, 2008. (ISBN 978-975-277-184-0).
10. Şakul, U., Bilecenoğlu, B. : (Bölüm Yazarlığı) Prostat Bezi Anatomisi, Prostat Hastalıkları Kitabı, Güneş Tıp Kitapevleri, 2008. (ISBN 978-975-277-184-0).
11. Şakul, U., Bilecenoğlu, B. : Baş ve Boynun Klinik Bölgesel Anatomisi. Özkan Matbaacılık, 2009. (ISBN 978-975-94242-2-0).
12. Şakul, U.: (Bölüm Yazarlığı) Woelfel’in Diş Anatomisi-Diş Hekimliği ile İlişkisi, Güneş Tıp Kitapevleri, 2010. (ISBN 978-0-7817-6860-3)

MAKALELER

1. İslam, C., Şakul, U., Güzel, B.: Real minimal diameter of the lower thoracic and lumbar vertebral pedicles. Clinical Anatomy, 7:271-274, 1994.
2. Güzel, B., Şakul, U., İslam, C., Köse, K.: A new method for differentiation of lumbar vertebrae. The Jikeikai Medical Journal, 41(2):111-116, 1994.
3. Şakul, U., İslam, C., Güzel, B.: The location and the number of nutrient foramina on the shafts of the upper limb bones. The Jikeikai Medical Journal, 41(2):117-122, 1994.
4. Şakul, U., Güzel, B., İslam, C.: The location and the number of nutrient foramina on the shafts of the lower limb bones. Acta Anatomica Nipponica, 69(4):410-411, 1994.
5. İslam, C., Güzel, B., Şakul, U.: Clinical importance of the minimal cancellous diameter of lower thoracic and lumbar vertebral pedicles. Clinical Anatomy, 9:151-154, 1996.
6. Aydınlıoğlu, A., Şakul, U., Diyarbakırlı, S.: A rare insertion site for abductor pollicis longus and extensor pollicis brevis muscles. Acta Anatomica, 163: 229-232, 1998.
7. Orhan. K., İçen. M., Bilecenoğlu, B., Şakul, BU,: Effect of third molar on the morphology of the pterygopalatine canal: a cone beam computed tomography study. Int J of Computer Assisted Radiol and Surgery, 5 (Suppl):S235-S240, 2010.
8.Orhan. K., Aksoy, S., Bilecenoğlu, B., Şakul, BU, Paksoy, CS.: Evaluation of bifid mandibular canals with cone-beam computed tomography in a Turkish adult population: a retrospective study. Surg Radiol Anat, 33:501-507, 2011.
9.Orhan. K., Şakul, BU, Öz, U., Bilecenoğlu, B.: “Investigation of pterygoid hamulus morphology using cone beam CT: preliminary results.”, Int J of Computer Assisted Radiol and Surg., 6 (Suppl 1): 382-383, 2011.
10. Orhan K, Icen M, Bilecenoglu B, Sakul BU, Kose SK.: The effect of posterior wall of maxillary sinus thickness on the morphology of the pterygopalatine canal.”, Int J of Computer Assisted Radiol and Surgery, 6 (Suppl 1): 383-384, 2011.
11. Orhan. K., Şakul, BU, Öz, U., Bilecenoğlu, B.: “Evaluation of pterygoid hamulus morphology using cone beam computed tomography.”, Oral Surg Oral Med Orak Pathol Oral Radiol Endod, 112:e48-e55, 2011.
12. Ozan, O., Orhan, K., Aksoy, S., İçen, M., Bilecenoğlu, B., Sakul, B.U.: The effect of removable partial dentures on alveolar bone resorption: A retrospective study with cone-beam computed tomography. Journal of Prosthodontics, 00:1-7, 2012.
13. Bilecenoglu, B., Onul, M., Altay, O.T., Sakul B.U: Cervicofacial emphysema after dental treatment with emphasis on the anatomy of the cervical fascia. The Journal of Craniofacial Surgery, Vol.23, Number 6, 544-548, Nov. 2012.
14. Şakul, U., Güzel, B., İslam, C., Köse, K.: Morphometry of lower thoracic and lumbar vertebrae (A clinicoanatomical study). The Italian Journal of Orthopaedics and Traumatology, 22(2):253-260, 1996.
15. Arıncı, K., Şakul, U., Elhan, A., Karan, O.: Brodmann'a göre cortex cerebri'nin topografik haritası (1-6. sahaların önem ve fonksiyonları). Optimal Tıp Dergisi, 1(1):33-39, 1989.
16. Arıncı, K., Şakul, U., Elhan, A., Karan, O.: Brodmann'a göre cortex cerebri'nin topografik haritası (7-52. sahaların önem ve fonksiyonları). Optimal Tıp Dergisi, 2(1):27-33, 1989.
17. Şakul, U., Elhan, A., Karan, O.: Dominant subkortikal yapıların lisandaki rolü. Nöroloji, 18(1):87-104, 1991.
18. Şakul, U., Türkaslan, K.: Variations of the median and the musculocutaneous nerves. Journal of Ankara Medical School, 13(3):259-262, 1991.
19. Şakul, U., Akbay, C., Acar, R.: Globus pallidus nöronlarının morfolojik tanımlanması: Işık mikroskobik bir çalışma. Optimal Tıp Dergisi, 4(4):183-188, 1991.
20. Acar, R., Şakul, U., Türkaslan, K., Ercan, A.: Fissura pterygomaxillaris'in şekil varyasyonları ve bunun klinik önemi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 44:537-544, 1991.
21. İslam, C., Şakul, U., Güzel, B.: Ön arka ve Mortis filmlerinde ayak bileği eklemi eksenlerinin karşılaştırılması. Van Tıp Dergisi, 1(2):19-22, 1994.
22. Şakul, U., Acar, R., Erdemli, E.: Erişkin insanlarda nervus trigeminus ve dallarının akson sayıları. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 1:39-41, 1994.
23. Aydınlıoğlu, A., Diyarbakırlı, S., Şakul, U., Keleş, P., Kırış, M., Erdoğan, A.: Burun dış duvarı anatomisinin sinus cerrahisi açısından incelenmesi. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 2:89-94, 1996.
24. Aydınlıoğlu, A., Diyarbakırlı, S., Şakul, U., Keleş, P., Arslan, H., Kırış, M.: Paranasal sinuslerin cerrahi anatomisi: Kadavra ve CT araştırması. I- Sinus maxillaris ve frontalis. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 3:6-11, 1997.
25. Aydınlıoğlu, A., Diyarbakırlı, S., Şakul, U., Keleş, P., Arslan, H., Kırış, M.: Paranasal sinuslerin cerrahi anatomisi: Kadavra ve CT araştırması. II- Sinus ethmoidales ve sphenoidalis. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 3:71-78, 1997.
26. Aydınlıoğlu, A., Şakul, U., Anadolu, Y., Diyarbakırlı, S., Keleş, P.: Morphometric evaluation of endoscopic endonasal dacryocystorhinostomy in human male cadavers. The Medicine and Health Journal, 3:9 - 13, 1999.
27. Aka, S., Şakul, B.U. : Kimliği bilinmeyen bir olgunun anatomik yeniden yüzlendirme tekniği ile kimliklendirilmesi. Adli Bilimler Dergisi, Cilt:6, Sayı:1,65-70, 2007.
28. Uzun, M., Şakul, BU.: Genital organların anatomik ve histolojik gelişimi. Türkiye Klin. Jinekoloji Obstetrik Özel Derg., Cilt:3, Sayı:2, 4-8, 2010.

text
Adı Soyadı Prof.Dr. Alper ATASEVER
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Oküler motor sistem, trase izleme

Seçili Yayınları / Tüm Yayınları

Lipid peroxid level increase in experimental hydrocephalus

H. Caner, A. Atasever, K. Kilinc, B. Durgun, S. Peker, O.E. Ozcan

Acta Neurochirurgica 1993; 121: 68-71

Unrotated left kidney associated with an accessory renal artery

A. Atasever, H.H. Çelik, B. Durgun, E. Yılmaz

Journal of Anatomy 1992; 181: 507

The peripheral course of the axons innervating the medial rectus muscle within the subarachnoid portion of the oculomotor nerve

A. Atasever, B. Durgun, T. Kansu, M. Cumhur

Journal of Anatomy 1992; 181: 499-501

Somatotopic organization of the axons innervating the superior rectus muscle in the oculomotor nerve of the rat

A. Atasever, B. Durgun, E. Yilmaz, H.H. Celik

Acta Anatomica 1993; 146: 251-254

Evaluation by angiography of the lateral dominance of the drainage of the dural venous sinuses.

B. Durgun, E.T.Ilgit , M.O. Cizmeli, A. Atasever

Surgical and Radiologic Anatomy 1993; 15: 125-130

Arteria thyroidea ima arising from the brachiocephalic trunk with bilateral absence of inferior thyroid arteries.

E. Yilmaz, H.H. Celik, B. Durgun, A. Atasever, S. Ilgi

Surgical and Radiologic Anatomy 1993; 15: 197-199

Labelling of the neurons in the rat superior cervical ganglion after injection of wheat-germ agglutinin-horseradish peroxidase into the contralateral ganglion: Evidence of transneuronal labelling

A. Atasever, S. Palaoglu, A. Erbengi, H.H. Celik

Journal of Anatomy 1994, 184: 93-97

Morphological assessment in pinealectomy and foetal pineal gland transplantation in rats: Part I

S. Palaoglu, A. Sungur, A. Atasever, S. Ruacan, S. Akalin, T. Ozgen, A. Erbengi

Acta Neurochirurgica 1994, 128: 1-7

Comparison of silk sutures and n-butyl-2-cyanoacrylate on the healing of skin wounds. A pilot study

C.B. Giray, A. Sungur, A. Atasever, K. Araz

Australian Dental Journal 1995; 40(1): 43-45

Clinical and electron microscope comparison of silk sutures and n-butyl-2- cyanoacrylate in human mucosa.

C.B. Giray, A. Atasever, B. Durgun, K. Araz

Australian Dental Journal 1997, 42(4): 255-8

Transient bone loss of distal radius and ulna following clean-cut tendon injuries, repair and passive mobilisation

E Kekilli, K Ertem, C Yagmur, A Atasever, N Elmalı, F Ceylan

Journal of Hand Surgery (European Volume) 2007, 32E: 3: 320-325

Melatonin Prevents Cyclosporine-Induced Hepatotoxicity in Rats

M Kurus, M Esrefoglu, G Sogutlu, A Atasever

Medical Principles and Practice 2009, 18: 407-410

text
Adı Soyadı Prof.Dr. Ertuğrul KILIÇ
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Beyin Felci; Nörobiyoloji

Seçili Yayınları / Tüm Yayınları

1. Elibol-Can B, Kilic E, Yuruker S, Jakubowska-Dogru E. Investigation into the effects of prenatal alcohol exposure on postnatal spine development andexpression of synaptophysin and PSD95 in rat hippocampus. Int J Dev Neurosci. 2014;33:106-14. doi: 10.1016/j.ijdevneu.2013.12.003. Epub 2013 Dec 21.

2. Elibol-Can B, Dursun I, Telkes I, Kilic E, Canan S, Jakubowska-Dogru E. Examination of Age- dependent effects of fetal ethanol exposure on behavior, hippocampal cellcounts, and doublecortin immunoreactivity in rats. Dev Neurobiol. 2013 Oct 29. doi: 10.1002/dneu.22143. [Epub ahead of print]

3. Karadeli HH, Aktekin B, Yilmaz B, Kilic E, Uzar E, Aci A, Bingol CA. Effects of melatonin on behavioral changes of neonatal rats in a model of cortical dysplasia. Eur Rev Med Pharmacol Sci. 2013 ;17(15):2080-4

4. Sehirli AO, Koyun D, Tetik S, Ozsavcı D, Yiğiner O, Cetinel S, Tok OE, Kaya Z, Akkiprik M, Kilic E, Sener G. Melatonin protects against ischemic heart failure in rats. J Pineal Res. (2013) 55(2):138-48

5. Kilic U, Yilmaz B, Reiter RJ, Yüksel A, Kilic E. Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice. Neuroscience. (2013) May 1;237:268-76

6. Kilic U, Kilic E, Tuzcu Z, Tuzcu M, Ozercan IH, Yilmaz O, Sahin F, Sahin K. Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond). (2013) 12;10(1):7

7. Kilic U, Yilmaz B, Ugur M, Yüksel A, Reiter RJ, Hermann DM, Kilic E. Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia (2012) Journal of Pineal Research, 52: 228-35. (I.F.: 5.85)

8. Kelestemur S, Kilic E, Uslu U, Cumbul A, Ugur M, Akman S, Culha M. Wound Healing Properties of Modified Silver Nanoparticles and their Distribution in Mouse Organs after Topical Application. (2012) Nano Biomedicine and Engineering, 4: 170-176.

9. Herz J, Reitmeir R, Hagen SI, Reinboth BS, Guo Z, Zechariah A, Elali A, Doeppner TR, Bacigaluppi M, Pluchino S, Kilic U, Kilic E, Hermann DM.Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. (2012) Neurobiology of Diseases, 45:1077-85 (I.F.: 4.9)

10. Reitmeir R, Kilic E, Reinboth BS, Guo Z, ElAli A, Zechariah A, Kilic U, Hermann DM. Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain.. (2012) Acta Neuropathologica. 123: 273-84 (I.F.: 7.5)

11. Mete F, Kilic E, Somay A, Yilmaz B. Effects of heat stress on endocrine functions & behaviour in the pre-pubertal rat. Indian J Med Res. 2012;135:233-9.

12. Reitmeir R., Kilic E, Kilic U, Bacigaluppi, M, ElAli A, Salani G, Pluchino S, Gassmann M, Hermann DM. Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodeling and contralesional pyramidal tract plasticity. (2011) Brain, 134:84-99 (I.F.: 9.603)

13. Kilic E, Elali A, Kilic U, Guo Z, Ugur M, Uslu U, Bassetti CL, Hermann DM. Role of Nogo-A in neuronal survival in the reperfused ischemic brain (2010) Journal of Cerebral Blood Flow and Metabolism, 30 (5), pp. 969-984. (I.F.: 5.741)

14. Tug, N., Kilic, U., Karateke, A., Yilmaz, B., Ugur, M., Kilic, E. Erythropoietin receptor-like immunostaining on human spermatozoa. (2010) Reproductive BioMedicine Online 21 (5):718-720. (I.F.: 2.380)

15. Yulug B, Erkol G, Kilic E. An interesting link between microgravity and psychiatric diseases. (2010) J Neuropsychiatry Clin Neurosci. 22: 451-g.e12-451.e12. . (I.F.: 2.362)

16. Yulug B, Ozan E, Kilic E. Brain-derived neurotrophic factor polymorphism as a genetic risk for depression? A short review of the literature. (2010) J Neuropsychiatry Clin Neurosci. Winter;22(1):123d.e5-123.e6

17. Muammer R, Kilic E, Hayran O. The effect of physiotherapy treatment on saliva decrease in children with cerebral palsy. Indian Journal of Physiotherapy and Occupational Therapy—An International Journal. (2010) 4: 129-131

18. Sahin K, Akdemir F, Tuzcu M, Sahin N, Onderci M, Ozercan R, Ilhan N, Kilic E, Seren S, Kucuk O. Genistein suppresses spontaneous oviduct tumorigenesis in quail. (2009) Nutr Cancer. 2009 Nov;61(6):799-806. (I.F.: 2.360)

19. Yalvac, M.E., Rizvanov, A.A., Kilic, E., Sahin, F., Mukhamedyarov, M.A., Islamov, R.R., Palotás, A. Potential role of dental stem cells in the cellular therapy of cerebral ischemia (2009) Current Pharmaceutical Design, 15 (33), pp. 3908-3916. (I.F.: 4.399)

20. Yulug B, Kilic E. Olanzapine does not aggrevate ischemic neuronal injury by focal cerebral ischemia: A dose related restriction of the neuroprotective effect? (2009) Medicinal Chemistry, 5 (3), pp. 279-282. (I.F.: 2.362)

21. Bacigaluppi M, Pluchino S, Peruzzotti-Jametti L, Kilic E, Kilic U, Salani G, Brambilla E, West MJ, Comi G, Martino G, Hermann DM. Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms (2009) Brain, 132 (8), pp. 2239-2251. (I.F.: 9.603)

22. Aydin O. Kahraman M. Kilic E. Çulha M. Surface-enhanced raman scattering of rat tissues (2009) Applied Spectroscopy, 63 (6), pp. 662-668. (I.F.: 2.062)

23. Yildirim G, Attar R, Ficicioglu C, Karateke A, Ozkan F, Kilic E, Yilmaz B, Yesildaglar N. Kombine letrozol ve melatonin tedavisinin deneysel rat endometriosis modelinde lezyon boyutları ve histopatolojik skorlar üzerine etkisi J Turkish German Gynecol Assoc. Year: 2009 Volume: 10 Issue: 4 199-204

24. Yulug B, Ozan E, Gönül AS, Kilic E. Brain-derived neurotrophic factor, stress and depression: A minireview (2009) Brain Research Bulletin, 78 (6), pp. 267-269. (I.F.: 2.281) X

25. Hermann DM, Kilic E. Therapeutic potential and possible risks of pleiotropic growth factors in ischemic stroke (2008) Stroke, 39 (11), p. e182. (I.F.: 6.499)

26. Cam E, Yulug B, Cengiz N, Poelkin E, Isik D, Bakar M, Ozan E, Kilic E. Melatonin: A suitable agent for depression associated with stroke? (2008) Journal of Neuropsychiatry and Clinical Neurosciences, 20 (4), pp. 498-500. (I.F.: 2.362)

27. Kilic E, Hermann DM, Spudich A, Kilic Ü, Rentsch KM, Vig R, Matter CM, Bassetti CL. ABCC1: A gateway for pharmacological compounds to the ischaemic brain (2008) Brain, 131 (10), pp. 2679-2689. (I.F.: 9.603)

28. Gao B, Kilic E, Baumann CR, Hermann DM, Bassetti CL. Gamma-hydroxybutyrate accelerates functional recovery after focal cerebral ischemia (2008) Cerebrovascular Diseases, 26 (4), pp. 413-419. (I.F.: 3.041)

29. Kilic E, Kilic U, Bacigaluppi M, Guo Z, Abdallah NB, Wolfer DP, Reiter RJ, Bassetti CL. Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice (2008) Journal of Pineal Research, 45 (2), pp. 142-148. (I.F.: 5.056)

30. Kilic U, Kilic E, Matter CM, Bassetti CL, Hermann DM. TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration (2008) Neurobiology of Disease, 31 (1), pp. 33-40. (I.F.: 4.852)

31. Bacigaluppi M, Pluchino S, Martino G, Kilic E, Hermann DM. Neural stem/precursor cells for the treatment of ischemic stroke (2008) Journal of the Neurological Sciences, 265 (1-2), pp. 73-77. (I.F.: 2.359)

32. Hédou GF, Koshibu K, Farinelli M, Kilic E, Gee CE, Kilic U, Baumgärtel K, Mansuy IM. Protein phosphatase 1-dependent bidirectional synaptic plasticity controls ischemic recovery in the adult brain (2008) Journal of Neuroscience, 28 (1), pp. 154-162. (I.F.: 7.452)

33. Kilic E, Hermann DM, Wippel A, Kilic Ü, Vogel P, Kim M, van der Putten H, Böttiger BW. Poxvirus-derived cytokine response modifier A (CrmA) does not protect against focal cerebral ischemia in mice (2007) Brain Research, 1185 (1), pp. 293-300. (I.F.: 2.494)

34. Yulug B, Cam E, Yildiz A, Kilic E. Buprenorphine does not aggrevate ischemic neuronal injury in experimental focal cerebral ischemia (2007) Journal of Neuropsychiatry and Clinical Neurosciences, 19 (3), pp. 331-334. (I.F.: 2.362)

35. Kilic Ü, Hermann DM, Kilic E, Järve, A, Guo, Z, Spudich, A, Bieber, K, Marti HH. Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways (2006) Journal of Neuroscience, 26 (48), pp. 12439-12446. (I.F.: 7.452)

36. Hermann DM, Kilic E, Spudich A, Krämer SD, Wunderli-Allenspach H, Bassetti CL. Role of drug efflux carriers in the healthy and diseased brain (2006) Annals of Neurology, 60 (5), pp. 489-498. (I.F.: 9.935)

37. Baumann CR, Kilic E, Petit B, Werth E, Hermann DM, Tafti M, Bassetti CL. Sleep EEG changes after middle cerebral artery infarcts in mice: Different effects of striatal and cortical lesions (2006) Sleep, 29 (10), pp. 1339-1344. (I.F.: 4.475)

38. Kilic E, Kilic Ü, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia (2006) FASEB Journal, 20 (8), pp. E307-E314. (I.F.: 7.049)

39. Kilic E, Kilic U, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. (2006) The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (8), pp. 1185-1187. (I.F.: 7.049)

40. Yulug B, Yildiz A, Güzel O, Kilic E, Schäbitz WR, Kilic E. Risperidone attenuates brain damage after focal cerebral ischemia in vivo (2006) Brain Research Bulletin, 69 (6), pp. 656-659. (I.F.:2.281)

41. Spudich A, Kilic E, Xing H, Kilic Ü, Rentsch KM, Wunderli-Allenspach H, Bassetti CL, Hermann DM. Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia (2006) Nature Neuroscience, 9 (4), pp. 487-488. (I.F.: 14.164)

42. Kilic E, Kilic U, Hermann DM. TAT fusion proteins against ischemic stroke: Current status and future perspectives (2006) Frontiers in Bioscience, 11 (2), pp. 1716-1721. (I.F.: 3.308)

43. Kilic E, Kilic Ü, Soliz J, Bassetti CL, Gassmaim M, Hermann DM. Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways (2005) FASEB Journal, 19 (14), pp. 2026-2028. (I.F.: 7.049)

44. Kilic, E, Kilic Ü, Hermann DM. TAT-GDNF in neurodegeneration and ischemic stroke (2005) CNS Drug Reviews, 11 (4), pp. 369-378. (I.F.: 4.432)

45. Kilic E, Kilic Ü, Bähr M, Hermann DM. Tissue plasminogen activator-induced ischemic injury is reversed by NMDA antagonist MK-801 in vivo (2005) Neurodegenerative Diseases, 2 (2), pp. 49-55. (I.F.: 2.989)

46. Spudich A, Frigg R, Kilic E, Kilic U, Oesch B, Raeber A, Bassetti CL, Hermann DM. Aggravation of ischemic brain injury by prion protein deficiency: Role of ERK-1/-2 and STAT-1 (2005) Neurobiology of Disease, 20 (2), pp. 442-449. (I.F.: 4.852)

47. Kilic E, Kilic Ü, Reiter RJ, Bassetti CL, Hermann DM. Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: Role of iNOS and Akt (2005) Journal of Pineal Research, 39 (2), pp. 151-155. (I.F.: 5.056)

48. Kilic Ü, Bassetti CL, Kilic E, Xing H, Wang Z, Hermann DM. Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2 (2005) Neuroscience, 134 (3), pp. 901-906. (I.F.: 3.556)

49. Grimm C, Hermann DM, Bogdanova A, Hotop S, Kilic Ü, Wenzel A, Kilic E, Gassmann M. Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration (2005) Seminars in Cell and Developmental Biology, 16 (4-5), pp. 531-538. (I.F.: 4.528)

50. Reiter RJ, Tan DX, Leon J, Kilic Ü, Kilic E. When melatonin gets on your nerves: Its beneficial actions in experimental models of stroke (2005) Experimental Biology and Medicine, 230 (2), pp. 104-117. (I.F.: 2.202)

51. Kilic Ü, Kilic E, Soliz J, Bassetti CL, Gassmann M, Hermann DM. Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2 (2005) FASEB Journal, 19 (2), pp. 249-251. (I.F.: 7.049)

52. Kilic E, Kilic Ü, Matter CM, Lüscher TF, Bassetti CL, Hermann DM. Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase (2005) Stroke, 36 (2), pp. 332-336. (I.F.: 6.499)

53. Kilic Ü, Kilic E, Reiter RJ, Bassetti CL, Hermann DM. Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice (2005) Journal of Pineal Research, 38 (1), pp. 67-71. (I.F.: 5.056)

54. Wang Y, Kilic E, Kilic Ü, Weber B, Bassetti CL, Marti HH, Hermann DM. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena (2005) Brain, 128 (1), pp. 52-63. (I.F.: 9.603)

55. Kilic E, Kilic Ü, Reiter RJ, Bassetti CL, Hermann DM. Prophylactic use of melatonin protects against focal cerebral ischemia in mice: Role of endothelin converting enzyme-1 (2004) Journal of Pineal Research, 37 (4), pp. 247-251. (I.F.: 5.056)

56. Kilic E, Weishaupt JH, Kilic Ü, Rohde G, Yulug B, Peters K, Hermann DM, Bähr M. The superoxide dismutase1 (SOD1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice (2004) Neuroscience, 128 (2), pp. 359-364. (I.F.: 3.556)

57. Reiter RJ, Kilic Ü, Tan DX, Gitto E, Sainz RM, Mayo JC, Leon J, Kilic E. Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage (2004) Polish Journal of Pharmacology, 56 (2), pp. 159-170. (I.F.: 2.167, The Pharmacological Reports)

58. Kilic Ü, Kilic E, Lingor P, Yulug B, Bähr M. Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro (2004) Acta Neuropathologica, 108 (1), pp. 65-68. (I.F.: 5.310)

59. Kilic Ü, Kilic E, Dietz GPH, Bähr M. The TAT protein transduction domain enhances the neuroprotective effect of glial-cell-line-derived neurotrophic factor after optic nerve transection (2004) Neurodegenerative Diseases, 1 (1), pp. 44-49. (I.F.: 2.989)

60. Kilic E, Kilic Ü, Yulug B, Hermann DM, Reiter RJ. Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator (2004) Journal of Pineal Research, 36 (3), pp. 171-176. (I.F.: 5.056)

61. Kilic E, Kilic Ü, Bassetti CL, Hermann DM. Intravenously administered recombinant tissue-plasminogen activator attenuates neuronal injury after mild focal cerebral ischemia in mice (2004) NeuroReport, 15 (4), pp. 687-689. (I.F.: 1.904)

62. Yulug B, Kilic U, Kilic E, Bähr M. Rifampicin attenuates brain damage in focal ischemia (2004) Brain Research, 996 (1), pp. 76-80. (I.F.: 2.494)

63. Kilic Ü, Kilic E, Dietz GPH, Bähr M. Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice (2003) Stroke, 34 (5), pp. 1304-1310. (I.F.: 6.499)

64. Kügler S, Kilic E, Bähr M. Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area (2003) Gene Therapy, 10 (4), pp. 337-347. (I.F.: 4.492)

65. Kilic E, Hermann DM, Kügler S, Kilic Ü, Holzmüller H, Schmeer C, Bähr M. Adenovirus-mediated Bcl-XL expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice (2002) Neurobiology of Disease, 11 (2), pp. 275-284. (I.F.: 4.852)

66. Kilic E, Dietz GPH, Hermann DM, Bähr M. Intravenous TAT-Bcl-XL is protective after middle cerebral artery occlusion in mice (2002) Annals of Neurology, 52 (5), pp. 617-622. (I.F.: 9.935)

67. Dietz GPH, Kilic E, Bähr M. Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction (2002) Molecular and Cellular Neuroscience, 21(1), pp. 29-37. (I.F.: 3.934)

68. Kilic E, Hermann DM, Isenmann S, Bähr M. Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice (2002) Journal of Pineal Research, 32 (2), pp. 106-111. (I.F.: 5.056)

69. Hermann DM, Kilic E, Kügler S, Isenmann S, Bähr M. Adenovirus-mediated glial cell line-derived neurotrophic factor (GDNF) expression protects against subsequent cortical cold injury in rats (2001) Neurobiology of Disease, 8 (6), pp. 964-973. (I.F.: 4.852)

70. Kilic E, Bähr M, Hermann DM. Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: Role of hemodynamic alterations (2001) Stroke, 32 (11), pp. 2641-2647. (I.F.: 6.499)

71. Dietz GPH, Kilic E, Bähr M, Isenmann S. Bcl-2 is not required in retinal ganglion cells surviving optic nerve axotomy (2001) NeuroReport, 12 (15), pp. 3353-3356. (I.F.: 1.904)

72. Hermann DM, Kilic E, Kügler S, Isenmann S, Bähr M. Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice (2001) Neurobiology of Disease, 8 (4), pp. 655-666. (I.F.: 4.852)

73. Knöll B, Isenmann S, Kilic E, Walkenhorst J, Engel S, Wehinger J, Bähr M, Drescher U. Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve (2001) Mechanisms of Development, 106 (1-2), pp. 119-127. (I.F.: 2.534)

74. Hermann DM, Kilic E, Hata R, Hossmann K-A, Mies G. Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice (2001) Neuroscience, 104 (4), pp. 947-955. (I.F.: 3.556)

75. Sönmez AS, Birincio?lu M, Aydin A, Kiliç E, Şahin N. Effects of misoprostol on the endometrium of ovariectomized rats (2000) Turkish Journal of Medical Sciences, 30(2),pp. 115-118.

76. Kilic E, Hermann DM, Hossmann KA. Recombinant tissue-plasminogen adivator-induced thrombolysis after cerebral thromboembolism in mice (2000) Acta Neuropathologica, 99 (3), pp. 219-222. (I.F.: 5.310)

77. Kilic E, Özdemir YG, Bolay H, Keleştimur H, Dalkara T. Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia (1999) Journal of Cerebral Blood Flow and Metabolism, 19 (5), pp. 511-516. (I.F.: 5.741)

78. Kilic E, Hermann DM, Hossmann KA. Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice
(1999) NeuroReport, 10 (1), pp. 107-111. (I.F.: 1.904)

79. Kilic E, Hermann DM, Hossmann KA. A reproducible model of thromboembolic stroke in mice (1998) NeuroReport, 9 (13), pp. 2967-2970. (I.F.: 1.904)








text
Adı Soyadı Prof.Dr. Süleyman YILDIRIM
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Hacettepe Üniversitesi 1994 Mikrobiyal Genomik Bilimler/Gıda Mikrobiyolojisi/North Carolina State Unıversity

Daha Önce Görev Yaptığı Yerler

-Misafir Bilim İnsanı - J. Craig Venter Institute, Rockville, MD, USA -Baş uzman araştırmacı - Walter Reed Army Institute of Research, Silver Spring, MD, USA -Doktora sonrası araştırmacı- University of Illinois, Urbana, USA -Doktora sonrası araştırmacı- Yale University School of Medicine, New Haven, CT, USA -Doktora (araştırma asistanı)- NC State University, Raleigh, NC, USA -Yüksek Lisans (araştırma asistanı) – Iowa State University, Ames, IA, USA

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

Yildirim, S., Yeoman, CJ., Chandra, SJ., Thomas, SM., Ho, M., Leigh, SR., White, BA., Wilson, BA., and Stumpf, RM. 2014. Primate vaginal microbiota exhibit species specificity without phylogenetic congruence or universal Lactobacillus dominance (ISME J. 2014 Jul 18. doi: 10.1038/ismej.2014.90. [Epub ahead of print]).

Stumpf RM, Wilson BA, Rivera A, Yildirim S, Yeoman CJ, Polk JD, White BA, Leigh SR. 2013. The primate vaginal microbiome: comparative context and implications for human health and disease. Am J Phys Anthropol. 57:119-34
Thompson, MG, Black, CC, Pavlicek, RL, Honnold, CL, Wise, MC, Alamneh, YA, Williams, R, Kirkup, BC, Yildirim, S, Si, Y, Green, RK, Kessler, JL, Moon, JK, Palys, TJ, Zurawski, DV. 2013. Validation of a Novel Murine Wound Model of Acinetobacter baumannii Infection. Antimicrob. Agents Chemother. Antomicrob. Agents Chemotherap. 58:1332-42

Amato KR, Yeoman CJ, Kent A, Righini N, Carbonero F, Estrada A, Gaskins HR, Stumpf RM, Yildirim S, Torralba M, Gillis M, Wilson BA, Nelson KE, White BA and Leigh SR*. 2013. Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes. J. ISME. 7:1344-53

Broadway M, Rogers E, Chang C., Huang I, Dwivedi P, Yildirim S, Schmitt S, Das A., and Ton-That H*. 2013. Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode. J. Bacteriology. 195:3774-83
Ratani SS, Siletzky RM, Dutta V, Yildirim S, Osborne JA, Lin W, Hitchins AD, Ward TJ, Kathariou S*. 2012. Heavy metal and disinfectant resistance of Listeria monocytogenes from foods and food processing plants. Appl Environ Microbiol. 78:6938-45

Yildirim, S. (2012). Terrestrial Vertebrate Animal Metagenomics, Non-domesticated Primates: Prosimians. In, Encyclopedia of Metagenomics, Animals. Ed. Karen E Nelson (Editor in Chief), Bryan A. White, Sarah Highlander, Francisco Rodriguez-Valera (Volume editors). Springer.

Yeoman CJ, Chia N., Yildirim S., Miller MEB., Kent A., Stumpf R., Leigh S.R., Nelson KE., White BA*., Wilson BA. 2011. Towards an Evolutionary Model of Animal-Associated Microbiomes. J. Entropy. 13:570-594.

Yildirim S, Yeoman, CJ., Sipos, M., Wilson, BA., Goldberg, TL., Stumpf, R, Leigh, SL., White, BA*, and Nelson, KE. 2010. Characterization of the Fecal Microbiome from Non-Human Wild Primates Reveals Species Specific Microbial Communities. PLoS ONE 5: e13963.
Yeoman CJ, Yildirim S, Thomas SM, Durkin AS, Torralba M, Sutton, G., Buhay, CJ., Ding, Y., Dugan-Rocha, SP., Muzny,DM., Qin, X., Gibbs, RA., Leigh, SR.,

Stumpf, R., White, BA., Highlander, SK., Nelson, JE., and Wilson, BA*. 2010. Comparative Genomics of Gardnerella vaginalis Strains Reveals Substantial Differences in Metabolic and Virulence Potential. PLoS ONE 5: e12411
Yildirim S., ElHanefi, D., Lin W, Hitchins AD, RM, Siletzky, and Kathariou, S*. 2010. Conserved genomic localization and sequence content of Sau3AI-like restriction-modification gene cassettes between Listeria monocytogenes Epidemic Clone I and selected strains of serotype 1/2a. Appl. Envir. Microb, 76:5577

Attardo, GM, Lohs, C., Alam, UH., Yildirim, S., and Aksoy, S*. 2008. Analysis of milk gland structure and function in Glossina morsitans: Milk protein production, symbiont populations and fecundity. J Insect Physiol. 54:1236-42
Yildirim S., Lin W, Hitchins AD, Jaykus LA, Altermann E, Klaenhammer TR, Kathariou S*. 2004. Epidemic clone-I specific genetic markers in strains of Listeria monocytogenes serotype 4b from foods. Appl Env. Microbiology. 70:4158-64

Johnson J, Jinneman K, Stelma G, Smith BG, Lye D, Messer J, Ulaszek J, Evsen L, Gendel S, Bennett RW, Swaminathan B, Pruckler J, Steigerwalt A, Kathariou S, Yildirim S, Volokhov D, Rasooly A, Chizhikov V, Wiedmann M, Fortes E, Duvall RE, Hitchins AD*. 2004. Natural atypical Listeria innocua strains with Listeria monocytogenes pathogenicity island-I genes. Appl Env. Microbiol. 70:4256-66
Yildirim S, Fuentes RG, Evangelista R, and Nikolov ZL*. 2002. Fractionation of Transgenic Corn for Optimal Recovery of Recombinant Enzymes. JAOCS. 79:809-814

text
Adı Soyadı Prof.Dr. Zübeyir BAYRAKTAROĞLU
E-Posta [email protected]
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi, İstanbul Tıp Fakültesi 2003 Fizyoloji, İstanbul Üniversitesi, İstanbul Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Fizyoloji Anabilim Dalı 2012 - 2016 Charite, Universitaetmedizin Berlin, Nöroloji ve Psikiyatri Bölümü, Nörofizik Grubu 2010 - 2012

Araştırma Alanları

Nörogörüntüleme, Biyoinformatik

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Prof.Dr. Cafer MARANGOZ
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Doç.Dr. İlknur KESKİN
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Samsun Ondokuz Mayıs Üniversitesi 1999 Selçuk Üniversitesi

Daha Önce Görev Yaptığı Yerler

Samsun 14 nolu MSO Selçuk Üniversitesi

Araştırma Alanları

Hücre kültürü, axolotl, rejenerasyon, stereoloji, periferik sinir, deri, yara iyileşmesi, beyin travması, üreme biyolojisi, histoloji eğitimi

Seçili Yayınları / Tüm Yayınları

Uluslararası hakemli dergilerde yayımlanan makaleler :
A.1 AYDIN KERAMETTIN,ÇOKLUK CENGIZ,AYAS BÜLENT,ÖNGER MEHMET EMIN,KESKIN ILKNUR,ÖZYASAR ALI FARUK,ASLAN HÜSEYIN,KAPLAN SÜLEYMAN (2011). Hippocampal cell loss
after an anterior and posterior anastomotic vein occlusion model in rats. International Journal of Developmental Neuroscience, 29(7), 717-722., Doi: 10.1016/j.ijdevneu.2011.05.013,
A.2 KESKIN ILKNUR,KAPLAN SÜLEYMAN,KALKAN SABIHA SERPIL,SÜTÇÜ MUSTAFA,ULKAY MUZAFFER BASAK,ESENER OSMAN BEHZAT BURAK (2015). Evaluation of neuroprotection by melatonin
against adverse effects of prenatal exposure to a nonsteroidal anti-inflammatory drug during peripheral nerve development. International Journal of Developmental Neuroscience, 41(41), 1-7., Doi: 10.1016/j.ijdevneu.2014.12.002,
A.3 ÜSTÜNDAG ÜNSAL VELI,SAHIN SADIK,AK KORAY,KESKIN ILKNUR,ALTURFAN EBRU ISIK (2015). The effects of tacrolimus on the activity and expression of tissue factor in the rat ovary with ischemia–reperfusion induced injury. Reproductive Biology, 15(3), 139-145., Doi: 10.1016/j.repbio.2015.07.002,
A.4 DEMIRCAN TURAN,ILHAN AYSE ELIF,AYTÜRK NILÜFER,YILDIRIM BERNA,ÖZTÜRK GÜRKAN,KESKIN ILKNUR (2016). A histological atlas of the tissues and organs of neotenic and metamorphosed
axolotl. Acta Histochemica, 118(7), 746-759., Doi: 10.1016/j.acthis.2016.07.006,
A.5 KESKIN ILKNUR,AYTÜRK NILÜFER,SÜTÇÜ MUSTAFA,KESKIN MUSTAFA,MÜDOK TANGÜL (2017). The use of platelet-rich plasma for storage of surplus harvested skin grafts. Plastic Surgery, 24(4), 1-8., Doi: 10.1177/2292550317693819,
A.6 KESKIN ILKNUR,SÜTÇÜ MUSTAFA,EREN HILAL,KESKIN MUSTAFA (2017). Exposure to Tumescent Solution Significantly Increases Phosphorylation of Perilipin in Adipocytes. Aesthetic Surgery Journal, 37(2), 239-245., Doi: 10.1093/asj/sjw156,
A.7 KESKIN ILKNUR,GÜNAL MEHMET YALÇIN,AYLA SULE,KOLBASI BIRCAN,SAKUL AYSE ARZU,KILIÇ ÜLKAN,GÖK ÖZLEM,ÖZBEK HANEFI (2017). Effects of Foeniculum vulgare essential oil compounds,
fenchone and limonene, on experimental wound healing. Biotechnic & Histochemistry , 1-9., Doi: 10.1080/10520295.2017.1306882,
A.8 ÖZBEK HANEFI,Bahadır Acıkara Özlem,KESKIN ILKNUR,Kirmizi Neriman Ipek,Ozbilgin Serkan,ERGENE ÖZ BURÇIN,KURTUL EKIN,Ozrenk Bade Cevriye,TEKIN MEHMET,SALTAN HAYRIYE
GÜLÇIN (2017). Evaluation of hepatoprotective and antidiabetic activity of Alchemilla mollis. Biomedicine & Pharmacotherapy, 86, 172-176., Doi: 10.1016/j.biopha.2016.12.005,
A.9 DEMIRCAN TURAN,KESKIN ILKNUR,DUMLU SEDA NILGÜN,AYTÜRK NILÜFER,AVSAROGLU MAHMUT ERHAN,akgün emel,ÖZTÜRK GÜRKAN,BAYKAL AHMET TARIK (2017). Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database. PROTEOMICS, 17(1-2), 1-5., Doi: 10.1002/pmic.201600338,
A.10 KESKIN ILKNUR,YILDIRIM BERNA,KOLBASI BIRCAN,ÖZTÜRK GÜRKAN,DEMIRCAN TURAN (2017). A Comparative Study of Fixatives for Axolotl Blastema Tissue. International Journal of Morphology, 35(1), 47-51., Doi: 10.4067/S0717-95022017000100009 ,
A.11 KARABULUT SEDA,KESKIN ILKNUR,Sagıroglu Yusuf Relationship between semen parameters in samples obtained from subfertile patients. Andrology-Open Access
A.12 KESKIN ILKNUR,GÜNAL MEHMET YALÇIN,AYTÜRK NILÜFER,KILIÇ ÜLKAN,OZANSOY MEHMET,KILIÇ ERTUGRUL Dose dependent neuroprotective effect of enoxaparın after cold induced traumatIc
braIn Injury. Neural Regeneration Research
A.13 ÖZBEK HANEFI,BAHADIR ACIKARA ÖZLEM,KESKIN ILKNUR,KIRMIZI NERIMAN IPEK,YIGITBASI TÜRKAN,SAKUL AYSE ARZU,SALTAN HAYRIYE GÜLÇIN Evaluation of Scorzonera sp. Root Extracts
and Major Compounds against Acute Hepatotoxicity Induced by Carbon Tetrachloride. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 79(4)
Uluslararası bilimsel toplantılarda sunulan ve bildiri kitaplarında (proceedings) basılan bildiriler :
B.1 SÜTÇÜ MUSTAFA,KESKIN ILKNUR,AKDAG OSMAN,KESKIN MUSTAFA,TOSUN ZEKERIYA,SAVACI NEDIM (2011). The Investigation of Repair Time and The Effect of Melatonine in Healing of Repaired Peripheral Nerve Injury. Plastic Surgery Special Joint Meeting, 263-264.
B.2 KESKIN ILKNUR,KAPLAN SÜLEYMAN,KALKAN SABIHA SERPIL,SÜTÇÜ MUSTAFA,ULKAY MUZAFFER BASAK,ESENER OSMAN BEHZAT BURAK (2012). An Evaluation of Neuroprotective Effects of
Melatonin Against Adverse Effects of Prenatal Exposure to a Non steroidal Anti Inflammatory Drug During The Peripheral Nerve Development. Asian and African Stereology Congress, 416 (Özet bildiri),
B.3 ALTURFAN EBRU ISIK,KESKIN ILKNUR,SÜTÇÜ MUSTAFA,YIGITBASI TÜRKAN,EMEKLI NESLIN (2014). Tissue Factor expression of adipose tissue in obesity. Fourth International Meeting on
Pharmacy &Pharmaceutical Sciences
B.4 KESKIN ILKNUR,AYTÜRK NILÜFER,SÜTÇÜ MUSTAFA,KESKIN MUSTAFA (2015). The Use of Platelet- Rich -Plasma for Storage of Surplus Harvested Skin Grafts. 12. Multional Congress on
MICROSCOPY, 313-316.
B.5 MÜDOK TANGÜL,KESKIN ILKNUR (2015). Geleneksel Mikroskop Egitiminden Dijital Mikroskop Egitimine Geçis Histoloji Egitiminde Globallesmenin Anahtarı mıdır?. Uluslararası Egitim Bilimleri ve Tıp Egitimi Sempozyumu (Özet bildiri),
B.6 ÖZBEK HANEFI,BAHADIR ACIKARA ÖZLEM,KESKIN ILKNUR,KIRMIZI NERIMAN IPEK,SAKUL AYSE ARZU,YIGITBASI TÜRKAN,SALTAN HAYRIYE GÜLÇIN (2016). Hepatoprotective Effects of Scorzonera L. Species on Carbon Tetrachloride-induced Liver Toxicity in Rats. 7. European Congress of Pharmacology, 566
B.7 KESKIN ILKNUR,DEMIRCAN TURAN,YILDIRIM BERNA,KOLBASI BIRCAN,ÖZTÜRK GÜRKAN (2016). A comparative study of fixatives for axolotl blastema tissue. 1. International Mediterranean Science and Engineering Congress, 3705 (Özet bildiri)
B.8 KESKIN ILKNUR,BEDRI NEJDA,MÜDOK TANGÜL (2016). Histoloji ve Embriyoloji Anabilim Dalında Yapılan Tezlerin Genel Profili. International Conference on Quality in Higher Education, 404-405. (Özet bildiri),
C. Ulusal hakemli dergilerde yayımlanan makaleler :
C.1 EKICI FATIH,KESKIN ILKNUR,ASLAN HÜSEYIN,ERISGIN ZÜLEYHA,ALTUNKAYNAK BERRIN ZÜHAL,GÖKÇIMEN ALPASLAN,ODACI ERSAN,KAPLAN SÜLEYMAN (2012). Does prenatal exposure to diclofenac sodium affect the total number of cerebellar granule cells in male juvenile and adult rats?. Journal of Experimental and Clinical Medicine, 29(1), 52-57., Doi: 10.5835/jecm.omu.29.01.013,
C.2 KESKIN ILKNUR,ÖZBEK HANEFI,AYTÜRK NILÜFER,MÜDOK TANGÜL (2015). Geleneksel Mikroskop Egitiminden Dijital Mikroskop Egitimine Geçis. Tıp Egitimi Dünyası, 14(42), 27-32.,
C.3 KESKIN ILKNUR,DEMIRCAN TURAN,BEDRI NEJDA,KÖROGLU NADIYE (2016). Fare Östrus Siklusu'nun Farklı Fazlarında PLIN2 ve PLIN3 Ekspresyonu. Haydarpasa Numune Egitim ve Arastırma Hastanesi Tıp Dergisi, 56(3), 131-142.,
C.4 DELILBASI BARIS ÇAGRI,AYTÜRK NILÜFER,AYDIN KADER,AKKOYUNLU MURAT,KESKIN ILKNUR (2016). Lateral Sinus Ogmentasyonunda Allojen Kemik Grefti ve Lökosit ve Plateletten Zengin
Fibrin (L-PRF) Kullanımının Mikroskobik ve Radyolojik Olarak Incelenmesi. Turkiye Klinikleri Journal of Oral and Maxillofacial Surgery-Special Topics, 2(3), 33-39.,
C.5 KESKIN ILKNUR,BEDRI NEJDA (2016). Yüksek Fruktoz Içerikli Beslenmenin Overlerde Perilipin Ekspresyonu ve Polikistik Over Gelisimi Ile Iliskisi. Zeynep Kamil Tıp Bülteni, 47(4), 106-110., Doi: 10.16948/zktipb.257211,
C.6 KESKIN ILKNUR,MÜDOK TANGÜL (2016). Kimerizm. Ibni Sina Tıp Bilimleri Dergisi, 2(1), 1-6.,
C.7 KESKIN ILKNUR (2017). accreditted by. Saglık Düsüncesi ve Tıp Kültürü Dergisi(27), 88-93.,
C.8 DEMIRCAN TURAN,KESKIN ILKNUR,GÜNAL MEHMET YALÇIN,ILHAN AYSE ELIF,KOLBASI BIRCAN,ÖZTÜRK GÜRKAN Axolotl cells and tissues enhances cutaneous wound healing in mice.
Journal of Experimental and Clinical Medicine, 33(4), Doi: 10.5835/jecm.omu.33.04.010,
C.9 AYLA SULE,KESKIN ILKNUR,Varlı Yelke Tuba,ÖNEL TUGÇE,KARAHÜSEYINOGLU SERÇIN ErkekInfertilitesinde Seminal Leptin Seviyelerinin Semen Parametreleri ve DNA Fragmantasyonu Ile Iliskisi. ZEYNEP KAMIL TIP BÜLTENI, 48(2), Doi: 10.16948/zktipb.288940,
C.10 KESKIN ILKNUR,KARABULUT SEDA Effects of density gradient sperm preparation on semen parameters and acrosomal status. Haydarpasa Numune Egitim ve Arastırma Hastanesi Tıp Dergisi, 57(2)
C.11 KESKIN ILKNUR,KOLBASI BIRCAN,AKHAN ASLI,ÇELIK HASAN,HANCI MUSTAFA,KESKIN MUSTAFA Hipermastinin eslik ettigi Bilateral Elastofibroma Dorsi Olgusu: Olası bir Iliskinin Sorgulanması. Türk Plastik Rekonstrüktif ve Estetik Cerrahi Dergisi

text
Adı Soyadı Doç.Dr. Esra ÇAĞAVİ
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Boğaziçi Üniversitesi 2002 Kalifornia Üniversitesi Los Angeles Kampüsü

Daha Önce Görev Yaptığı Yerler

Gebze Yüksek Teknoloji Enstitüsü

Araştırma Alanları

Araştırmalarımda genel ilgi alanım: embriyonik ve indüklenmiş kök hücre sistemi kullanarak kalp-damar gelişimi ve hastalıklarının moleküler temellerinin araştırması ve tedavi yöntemleri geliştirilmesidir. Özel alt başlıklar ise: • Embriyonik kök hücrelerden kalp kök hücresi ve kardiyomiyosit elde edilmesi • Kalp kök hücrelerinin farklılaşma ve kendini yenilemesinde gerekli sinyal ileti mekanizmalarının tanımlanması • Kalp ve damar hastalıkları tedavisinde kullanılmak üzere yeni kalp doku mühendisliği uygulamalarının geliştirilmesi • Hastaların deri dokusundan uyarılmış pluripotent kök hücre elde edilmesi ve in vitro modelleme yapılarak hastalık mekanizmasının araştırılmasıdır.

Seçili Yayınları / Tüm Yayınları

1) Cagavi E., Bartulos O., Suh C. Y., Sun B., Yue Z., Jiang Z., Yue L., Qyang Y. “Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation” Plos One (2014). DOI: 10.1371/journal.pone.0110752.

2) Dunworth W. P., Cardona-Costa J., Cagavi E., Kim J. D., Meadows S., Fisher J. C., Wang Y., Cleaver O., Qyang Y., Ober E. A., and Jin S. W. “Bone Morphogenetic Protein 2 Signaling Negatively Modulates Lymphatic Development in Vertebrate Embryos” Circ Res 114 (1) :56-66 (2014).

3) Ge X., Ren Y., Bartulos O., Lee M. Y., Yue Z, Kim K. Y., Li W., Amos P. J., Cagavi Bozkulak E., Iyer A., Zheng W., Zhao H., Martin K. A., Kotton D. N., Tellides G., Park I. H., Yue L., Qyang Y. “Modeling Supravalvular Aortic Stenosis Syndrome Using Human Induced Pluripotent Stem Cells” Circulation 126(14):1695-704 (2012).

4) Alcon A., Cagavi Bozkulak E., Qyang Y. “Regenerating Functional Heart Tissue for Myocardial Repair” Cell Mol Life Sci 69(16):2635-56 (2012).

5) Amos P. J., Cagavi Bozkulak E., Qyang Y. “Methods of Cell Purification: A Critical Juncture for Laboratory Research and Translational Science” Cells Tissues Organs 195(1-2):26-40 (2012).

6) Lee M. Y., Cagavi Bozkulak E., Schliffke S., Amos P. J., Ren Y., Ge X., Ehrlich B. E., Qyang Y. “High Density Cultures of Embryoid Bodies Enhanced Cardiac Differentiation of Murine Embryonic Stem Cells” Biochem Biophys Res Commun 416, 51-57 (2011).

7) Lee M. Y., Sun B., Schliffke S., Yue Z., Ye M., Paavola J, Cagavi Bozkulak E., Amos P.J., Ren Y., Ju R., Jung Y. W., Ge X., Yue L., Ehrlich B. E., Qyang Y. “Derivation of Functional Ventricular Cardiomyocytes Using Endogenous Promoter Sequence from Murine Embryonic Stem Cells” Stem Cell Res 8, 49–57 (2011).

8) Bozkulak E. C., Weinmaster G. “Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling” Mol Cell Bio 29(21), 5679–5695 (2009).

9) Rooke N., Vadim M., Cagavi E., Black D. L. “Roles for SR Proteins and hnRNP A1 in the Regulation of c-src Exon N1” Mol Cell Bio 23(6), 1874-1884 (2003).

text
Adı Soyadı Doç.Dr. Mustafa GÜZEL
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Hacettepe Üniversitesi 1987 Clemson Üniversitesi Mühendislik ve Doğal Bilimler Fakültesi Medisinal Kimya Anabilim Dalı

Daha Önce Görev Yaptığı Yerler

MEB (Kimya Öğretmenliği, 1988-1993, İzmir Yüksek Teknoloji Enstitüsü (Araştırma Görevlisi (1993-2000), Clemson Üniversitesi (Öğretim Görevlisi 1997-1998), Northeastern Üniversitesi (Misafir Araştırma Görevlisi ve Organik Kimya Lab. Koordinatörü, 1998-2000), ArQule Inc. (Senyör. Sentetik Organik Kimyacı, 2000), TransTech Pharma Inc. (Proje sorumlusu, uzman bilim insanı, medisinal kimya lab. direktörü, 2001-2014).

Araştırma Alanları

• Yenilikçi ilaç Ar-Ge çalışmaları, ilaç keşif ve geliştirme özellikle kanser, kinaz inhibitörleri, Tip-2 şeker hastalığının tedavisi için G Proteinle Çiftleşmiş Reseptörlerinin incelenmesi, obezlik, merkezi sinir sistemi hastalıkları (Alzheimer ve Parkinson gibi), römatoit artiritis gibi inflammasyonla ilgili ilaç geliştirilmesi. • Yeni ilaç moleküllerini geliştirmek üzere simetrik veya asimetrik moleküllerin dizayni ve senteziyle ilgili Ar-Ge çalişmaları. Doğal bileşiklerin aktif maddelerinin izolasyon, sentezleme metodları ve teknikleri. • Katalitik asimetrik indüksiyon reaksiyonlarının mekanizmalarının incelenmesi ve bunlardan çıkarak biyoljik sistemlerde aktif olabilecek ilaçlarin geliştirilip sentezleme yöntemleri.

Seçili Yayınları / Tüm Yayınları

1. "Gender Satisfaction among Type 2 Diabetes Patients: A Comparison between Intensive Diets, Lifestyle Intervention with Medication Controlled Management"; Abdulbari Bener, Abdulla O. A. A. Al-Hamaq, Funda Çatan, Kaleem U. Rajput and Mustafa Guzel; British Journal of Medicine & Medical Research, volume: 18, number: 7, page:1-13, 2016. DOI: 10.9734/BJMMR/2016/29418.
2. "Medisinal Kimyanın Yeni İlaç Keşif ve Geliştirmedeki Rolü ve Önemi:The Role and Importance of Medicinal Chemistry in Novel Drug Discovery and Development"; Mustafa Güzel, ve Sezgin Kiren; Turkish Clinics, Turkiye Klinikleri J Pharm Sci 2016;5(1):36-45, 2016. DOI: 10.5336/pharmsci.2015-48211.
3. "Synthesis of Substituted Pyridines from 1,2-Nucleophilic Addition Products of Functionalized N-Acyl-2,3-dihydropyridones"; Mustafa Guzel, Joshua Watts, Matthew McGilvary, Marcus Wright, and Sezgin Kiren; Tetrahedron Letters, volume: 56, number: 38, (2015), p:5872. doi:10.1016/j.tetlet.2015.07.045.
4. “Estimation of Octanol-Water Partition Coefficient Using Cationic Gemini Surfactants by Micellar Electrokinetic Chromatography’; Mustafa Guzel, Cevdet Akbay, Yatzka Hoyos , David H. Ahlstrom; Journal of Chromatography and Separation Techniques, volume: 6, number: 4, (2015), p-. doi:10.4172/2157- 7064.1000275.
5. "Induction of Heme Oxygenase I (HMOX1) by HPP-4382: A novel modulator of Bach-1 activity”; Otis Attucks, Kimberly Jasmer, Mark Hannink, Jareer Kassis, Zhenping Zhong, Suparna Gupta, Sam Victory, Mustafa Guzel, Dharma Polisetti, Robert Andrews, Adnan Mjalli, and Matthew Kostura; PLoSOne, 9, 7, (2014), p:1-12, e101044.
6. "Substituted Pyran Derivatives Useful as Antitumor Agents"; Mustafa Guzel, Devi Reddy, Rongyuan Xie, Dharma R. Polisetti, Stephen Davis, Soumya Sahoo, Hassan El Abdelloui, and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent #US 61/892,053, 2013.
7. "Substituted Fused Oxazoline Derivatives Useful as Antitumor Agents"; Mustafa Guzel, Devi Reddy, Rongyuan Xie, Dharma R. Polisetti, Soumya Sahoo, Stephen Davis, Mohan Rao, Kalpathy Santhosh, and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent #US 61/892,018, 2013.
8. "Characterization and application of molecular binary mixed molecular micelles of sodium10-undecenyl sulfate and sodium N-undecenyl leucinate as pseudostationary phases in micellar electrokinetic chromatography"; Cevdet Akbay, Hamid H. Ahmed, Hakan Arslan, Brittany Graham, and Mustafa Guzel; Talanta, 99, (2012), 441-449.
9. " Study of chemical selectivity of binary mixed micelles of sodium 10-undecenyl sulfate and sodium N-undecenyl leucinate using linear solvation energy reletionships model"; Hamid H. Ahmed, David M. Ahlstrom, Hakan Arslan, Mustafa Guzel, and Cevdet Akbay; Journal of Chromatography A, 1236, (2012), 207-214.
10. “Novel Anticancer agents for hexokinase inhibition-Substituted cyclic-3-indole derivatives”; Mustafa Guzel, Rongyuan Xie, Dharma R. Polisetti, Robert C. Andrews, Adnan M. M. Mjalli, and Stephen Davis; High Point Pharmaceuticals Inc., High Point, NC, Application No: HPP 3018.001 US; patent manuscript submitted, 2013.
11. “Substituted Benzimidazole Derivatives and Methods of Use to Treat Oxidative Stress”; Mustafa Guzel, Sam Victory, Dharma R. Polisetti, Mathew Kostura, Adnan M. M. Mjalli, Otis Attucks, and Jareer Kassis; High Point Pharmaceuticals Inc., High Point, NC, Application No: HPP 3007.000 US; patent manuscript submitted, 2012.
12. “Substituted Pyridine derivatives, Pharmaceutical Compositions, and Methods of Use to Treat Oxidative Stress”; Mustafa Guzel, Sam Victory, Bapu Gaddam, Dharma R. Polisetti, Mathew Kostura and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent # WO 2011/022216, (02, 24, 2011).
13. “Oxadiazoanthracene Compounds, for Treatments of Diabetes”; Scott T. Yokum, Mustafa Guzel, Kalpathy C. Santhosh, Dharma R. Polisetti, Daniel P. Christen, Adnan M. Mjalli, and Stephen T. Davis; TransTech Pharma Inc., High Point, NC, , Patent # US 2011/7906507 (03, 15, 2011).
14. “In Silico Ligand-Receptor Docking of Potentially Selective Butyrylcholinesterase Inhibitors Structurally Related to the Marine Natural Product Debromoflustramine B”; Miguel O. Mitchell, Robert W. Figliozzi and Mustafa Guzel; Medicinal Chemistry, Volume 6, Number 3, 2010, Pp. 141-143.
15. “Substituted Pyridine derivatives, Pharmaceutical Compositions, and Methods of Use to Treat Oxidative Stress”; Mustafa Guzel, Sam Victory, Bapu Gaddam, Dharma R. Polisetti, Mathew Kostura and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent # US 2010/044508, (05, 08, 2010).
16. “Mandelic Acid Derivatives and Preparation Thereof”; Mustafa Guzel, Scott T. Yokum, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # US 2010/0036150, (02,11, 2010).
17. “Oxadiazoanthracene Compounds, Compositions of Oxadiazoanthracene Compounds and Methods of Treatment Using the Same”; Scott T. Yokum, Mustafa Guzel, Kalpathy C. Santhosh, Dharma R. Polisetti, Daniel P. Christen, Adnan M. Mjalli, and Stephen T. Davis; TransTech Pharma Inc., High Point, NC, , Patent # US 2010/0324033 (12, 23, 2010).
18. “Substituted Azoanthracene Derivatives, Pharmaceutical Compositions, and Methods of Use Thereof”; Mustafa Guzel, Scott T. Yokum, Kalpathy C. Santhosh, Dharma R. Polisetti, Chris Behme, Adnan M. Mjalli, and Stephen T. Davis”; TransTech Pharma Inc., High Point, NC, Patent # WO 2010/4824 (07, 10, 2010).
19. “Tricyclic Compounds as Modulators of TNF-? Synthesis”; Mustafa Guzel, Mathew Kostura, Adnan M. Mjalli, Bapu Gaddam, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # US 2010/0190808 (07, 29, 2010).
20. “Oxadiazoanthracene Compounds, for Treatments of Diabetes”; Scott T. Yokum, Mustafa Guzel, Kalpathy C. Santhosh, Dharma R. Polisetti, Daniel P. Christen, Adnan M. Mjalli, and Stephen T. Davis; TransTech Pharma Inc., High Point, NC, , Patent # WO 2009/111700 (11, 09, 2009).
21. “Aryl Carbonyl Derivatives as Therapeutic Agents-Part-II”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2009/7541373 (06, 02, 2009).
22. “Tricyclic Compounds as Modulators of TNF-? Synthesis as PDE4 Inhibitors”; Mustafa Guzel, Mathew Kostura, Adnan M. Mjalli, Bapu Gaddam, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # WO 2009/094528, (07, 30, 2009).
23. “Aryl, and Hetoroaryl Compounds, Compositions, and Methods of Use”; Mustafa Guzel, Murty Arimilli, Muralidhar Bundlela, Elizabeth Guo, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2008/7459472 (12, 02, 2008).
24. “Aryl Carbonyl Derivatives as Therapeutic Agents-Part-I”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2008/7384967 (06, 10, 2008).
25. “Mandelic Acid Derivatives and Preparation Thereof”; Mustafa Guzel, Scott T. Yokum, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # WO 2008/051563, (05, 02, 2008).
26. “Exploiting ?-Shielding Interactions of ?6 Arene Chromium (0) Complexes: New Auxiliaries derived from the Biogenic Chiral Pool”; Jane Li, Longfei Xie, Mustafa Guzel, Steven B. Heaton, Dong Ma, Amy E. Kallmerten, and Graham B. Jones; Journal of Organometallic Chem., 2007,. 692, 5459-5473.
27. “Aryl, and Hetoroaryl Compounds, Compositions, and Methods of Use”; Mustafa Guzel, Murty Arimilli, Muraldhar Bundlela, Elizabeth Guo, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2005/0059713 (03, 17, 2005).
28. “Novel Aryl Compounds for Antiviral Activity: Amide Derivatives as Therapeutic Agents”; Mustafa Guzel, Murty Arimilli, Muraldhar Bundle, Elizabeth Guo, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # WO 2005/014534 (02, 17, 2005).
29. “Aryl Carbonyl Derivatives as Therapeutic Agents”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2004/0122235 (06, 24, 2004).
30. “Aryl Carbonyl Derivatives as Therapeutic Agents”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # WO 2004/002481 (01, 08, 2004).
31. “Novel GlucoKinase Activators: Amide Derivatives as Therapeutic Agents-Part-II”; Mustafa Guzel, Kalpaty C. Santhosh, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2003/0171411 (09,11, 2003).
32. “Novel GlucoKinase Activators: Amide Derivatives as Therapeutic Agents-Part-I”; Mustafa Guzel, Kalpaty C. Santhosh, Adnan M. Mjalli, Robert C. Andrews, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC; Patent # WO 03/055482 (07, 10, 2003).
33. “Enantioselective Catalysis Using Planar Chiral ?6 Arene Chromium Complexes: 1,2-Diols as Cycloaddition Catalysts”; Graham B. Jones, Mustafa Guzel and Steven B. Heaton; Tetrahedron: Asymmetry, 2000, 11, 4303-4320.
34. “Exploiting ?-Shielding Interactions in a ?6 Arene Complexes Chiral Auxiliary”; Graham B. Jones, and Mustafa Guzel; Tetrahedron Letters, 2000, 41, 4695-4699.
35. “Catalytic Enantioselective Cycloaddtions: A readily Available Diels-Alder Catalyst”; Graham B. Jones, and Mustafa Guzel; Tetrahedron: Asymmetry, 2000, 11, 1267-1271.
36. “Stereoselective Route to Mitosenes via Tricarbonyl ?6 Arene Chromium (0) Complexes”; Graham B. Jones, Mustafa Guzel, and Jude E. Mathews; Tetrahedron Letters, 2000, 41, 1123-1126.
37. “Enantioselective Cycloadditions Catalyzed by Face Resolved Arene Chromium (0) Carbonyl Complexes”; Graham B. Jones, and Mustafa Guzel; Tetrahedron: Asymmetry, 1998, 9, 2023-2026.
38. “Refined Enantioselective Methylation Catalysts: Improved Routes to Bifunctional C5 Synthons”; Graham B. Jones, Mustafa Guzel, and Brant J. Chapman; Tetrahedron: Asymmetry, 1998, 9, 901-905.
39. “On the Origins of Enantioselectivity in Oxazaborolidine Mediated Carbonyl Reductions”; Graham B. Jones, Steven B. Heaton, Brant J. Chapman, and Mustafa Guzel; Tetrahedron: Asymmetry, 1997, 8, 3625-3636.

text
Adı Soyadı Doç.Dr. Sultan Sibel ERDEM
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Marmara Universitesi 2001 Louisiana State Universitesi

Daha Önce Görev Yaptığı Yerler

Harvard Tip Fakultesi ve Massachusetts Genel Hastanesi

Araştırma Alanları

Hedefe yönelik ilaçlar ve nanopartikul ilaç sistemleri, kanserin fotodinamik terapi ile tedavisi, cesitli hastaliklarin teshis ve tedavisinde kullanilanilan biomarker hedefli floresan sistemler, isikla aktive olan moleküllerin tasarim ve sentezi.

Seçili Yayınları / Tüm Yayınları

Erdem, Sibel S. Near-IR Dyes and Their Use in Medical Sciences" MUSBED, 2016, in press

Hara, T., Ughi, G.J., McCarthy, J.M Erdem, Sibel S., Mauskapf, A., Lyon, S.S, Fard, A, M., Edelman, E.E., Tearney, G. J., and Jaffer, F. A. “Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo” European Heart Journal, in press

Stein-Merlo, Kessinger, C. W., Erdem, Sibel S, Zelada, H., Hilderbrand, S.H., Lin, C. P., J.G Tearney, J.G., Jaff, M. R., Reed, G.R., Henke, P.K., McCarthy, J.M., Farouc A. Jaffer, F.A. Blood “Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study” Theranostics, 2015; 5(12): 1317-1327

Erdem, Sibel S.; Konishi, Masanori.; Weissleder, Ralph.; Lichtman, Andrew H.; McCarthy, Jason, R.; Libby, Peter. “Imaging granzyme B activity assesses immune mediated myocarditis.” Circulation Research, 2015, 117(6), 502-512.

Erdem, Sibel S.; Khan, Shazia, Palanasami, Akilan and Hasan, Tayyaba. “Rapid, Low-cost Fluorescent Assay of Beta-Lactamase Derived Antibiotic Resistance and Related Antibiotic Susceptibility, Journal of Biomedical Optics, 2014, 19, 10, 105007.

Avci, Pinar; Erdem, Sibel S.; Hamblin, Michael R. “Photodynamic Therapy: One Step Ahead with Self-Assembled Nanoparticles” Journal of Biomedical Nanotechnology, 2014, 10, 1–16.

Spring, Q. Bryan; Abu-Yousif, O. Adnan.; Palanisami, Akilan.; Zheng, Xiang.; Anbil,
Sriram; Sears, R. Bryan; Mensah, B. Lawrence; Goldschmidt, Ruth; Erdem, Sibel S;Oliva, Esther; Hasan, Tayyaba. “Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function activatable immunoconjugates” Proceeding of National Academia of Science U.S.A ., 2014, 11, 10, E933-E942.

Erdem, Sibel S; Fronczek, Frank R.; Watkins, Steven F. “Bis[2,3,4-trimethyl-5-[(3,4,5-trimethyl-2H-pyrrol-2-yl-idene-? N)meth-yl]-1H-pyrrolato-? N]copper(II)” Acta Crystallogr. Sect E Struct. Rep. Online. 2012, 68 (11), 1335-1336.

McCarthy, Jason R.; Sazonova, Irina Y.; Erdem, Sibel S.; Hara, Tetsuya.; Thompson, Brian D.; Patel, Purvish.; Botnaru, Ion.; Lin, Charles P.; Reed, Guy L.; Weissleder, Ralph and Jaffer, Farouc A. “Multifunctional Nanoagent for Thrombus-targeted Fibrinolytic Therapy” Nanomedicine , 2012,7, 1017-1028.

Nesterova, Irina V.; Bennett CA.; Erdem, Sibel S.; Hammer, Robert P.; Deininger PL. and Soper, Steven A. “Near-IR single fluorophore quenching system based on phthalocyanine (Pc) aggregation and its application for monitoring inhibitor/activator action on a therapeutic target: L1-EN” Analyst , 2011, 136, 1103-1105.

McCarthy, Jason R.; Bhaumik, Jayeeta; Karver, Mark R.; Erdem, S. Sibel.; Bardon,
Kevin.; and Weissleder, Ralph. “Targeted Nanoagents for the Detection of Cancers” Molecular Oncology, 2010, 4, 511-528.

Erdem, Sibel S.; Nesterova, Irina V.; Soper, Steven A. and Hammer, Robert P. “Monoamine Functionalized Phthalocyanines: Microwave-Assisted Solid-Phase Synthesis and Bioconjugation Strategies” The Journal of Organic Chemistry , 2009, 74, 9280-9286.

Nesterova, Irina V.; Erdem, Sibel S.; Pakhomov, Serhii.; Hammer, Robert P. and Soper, Steven A. “Phthalocyanine Dimerization-Based Molecular Beacons Using Near-IR Fluorescence” The Journal of American Chemical Society , 2009, 131, 2432-2433.

Erdem, Sibel S.; Nesterova, Irina V.; Soper, Steven A. and Hammer, Robert P. “Solid- Phase Synthesis of Asymmetrically Substituted “AB3 ” Type Phthalocyanines”, The Journal of Organic Chemistry , 2008, 73, 5003-5007.

text
Adı Soyadı Doç.Dr. Bilal Ersen KERMAN
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Doç.Dr. Şule AYLA
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Uludağ Üniversitesi 1998 İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

Şanlıurfa Kadın Doğum Hastanesi Süleymaniye Kadın Doğum Hastanesi Zeynep Kamil Kadın Hastalıkları ve Doğum Eğitim ve Araştırma Hastanesi

Araştırma Alanları

Kanser, Kanser kök hücre, Infertilite, In vitro fertilizasyon, Sperm DNA hasarı, Hücre kültürü, tekrarlayan düşükler, immünohistokimya, elektron mikroskobu

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Dr.Öğr.Üye. Taha KELEŞTEMUR
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Istanbul Universitesi 2009 İstanbul Medipol Üniversitesi, Necmettin Erbakan Üniversitesi

Daha Önce Görev Yaptığı Yerler

Yeditepe Üniversitesi

Araştırma Alanları

Travmatik Beyin Hasarı, Epilepsi, Hipoksi

Seçili Yayınları / Tüm Yayınları

Kelestemur T “A Reproducible Model of Traumatic Brain Injury in Rats: The Roles of Phosphorylated JNK-1/2” FEPS September 2012 / Santiago de Compostela / Spain

Keleştemur T “Investigation of the Pathophysiological Changes in the Signalling Pathway and Sensory and Motor Behavioral Changes after Traumatic Brain Injury in Rats” TFBD 38 th. National Physiology Meeting September 2012 / Trabzon / Turkey

Keleştemur T “Investigation the Effects of Memantine and Melatonin Treatment after Traumatic Brain Injury in Mice” 11th National Neuroscience Meeting April 2013 /Izmir / Turkey

Keleştemur T “P2x7 Reseptör Baskılanması Ve Aktivasyonunun Beyin- Epileptiform Aktivitesi, Mikrodolaşımı Ve Hücre İçi Sinyal İletim Molekülleri Üzerine Olan Etkileri" 40. Ulusal Fizyoloji Kongresi Eylül 2014 Kayseri / Türkiye

Keleştemur T "Inhibition but not activation of P2X7 receptors improves brain epileptiform activity in mice: Role of NOS activity" 44th Annual Meeting of the Society for Neuroscience November 2014 / Washington D.C. / USA

Kilic E, Reitmeir R, Kilic U, Caglayan AB, Beker MC et al. : HMG-CoA Redcutase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Conta-Lesional Pyramidal Tract Plasticity After Focal Cerebral Ischemia. Fron. Cell. Neurosci.. (8) : 422-432, 2014

Beker M.C., Caglayan A.B., Kelestemur T., Caglayan B., Yalcin E. : Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation. Oncotarget. 6 (29) : 1-11, 2015

Taha Kelestemur,Burak Yulug,Ahmet Burak Caglayan,Mustafa Caglar Beker,Ulkan Kilic,Berrak Caglayan,Esra Yalcin,Reyhan Zeynep Gundogdu,Ertugrul Kilic : Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine. Neuroscience Letters. 0 (0) : 0-0, 2015

text
Adı Soyadı Dr.Öğr.Üye. Mustafa Çağlar BEKER
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Yeditepe Üniversitesi 2012 İstanbul Medipol Üniversitesi

Daha Önce Görev Yaptığı Yerler

-

Araştırma Alanları

Beyin Felci, Deney Hayvanlarında Davranış Testleri, Plastisite

Seçili Yayınları / Tüm Yayınları

SCI, SSCI, AHCI indekslerine giren dergilerde yayınlanan makaleler

1. Caglayan B, Caglayan AB, Beker MC, Yalcin E, Beker M, Kelestemur T, Sertel E, Ozturk G, Sahin F, Kilic E, (2017) “Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice” Exp. Neurol. 29;296:23-31. doi: 10.1016/j.expneurol.2017.06.024.
2. Demirci S, Dogan A, Basak Turkmen N, Telci D, Caglayan AB, Beker MC, Kilic E, Ozkan F, Dede B, Sahin F, (2017) “Poloxamer P85 increases anticancer activity of Schiff base against prostate cancer in vitro and in vivo” Anticancer Drugs. doi: 10.1097/CAD.0000000000000528.
3. Beker MC, Caglayan B, Yalcin E, Caglayan AB, Turkseven S, Gurel B, Kelestemur T, Sertel E, Sahin Z, Kutlu S, Kilic U, Baykal AT, Kilic E, (2017) “Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT” Mol Neurobiol. doi: 10.1007/s12035-017-0524-4.
4. Kilic U, Caglayan AB, Beker MC, Gunal MY, Caglayan B, Yalcin E, Kelestemur T, Gundogdu RZ, Yulug B, Yilmaz B, Kerman BE, Kilic E, (2017) “Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice” Redox Biol. 12:657-665. doi: 10.1016/j.redox.2017.04.006.
5. Eren Z, Gunal MY, Ari E, Coban J, Cakalagaoglu F, Caglayan B, Beker MC, Akdeniz T, Yanikkaya G, Kilic E, Kantarci G, (2016) “Pleiotropic and Renoprotective Effects of Erythropoietin Beta on Experimental Diabetic Nephropathy Model”. Nephron 132:292-300. doi: 10.1159/000444649.
6. Kartal O, Aydinoz S, Kartal AT, Kelestemur T, Caglayan AB, Beker MC, Karademir F, Suleymanoglu S, Kul M, Yulug B, Kilic E (2016) “Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3”. Metabolic brain disease. 31(4):827-35. doi: 10.1007/s11011-016-9816-z.
7. Kelestemur T, Yulug B, Caglayan AB, Beker MC, Kilic U, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E (2016) “Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine”. Neuroscience letters 612:92-97. doi: 10.1016/j.neulet.2015.11.043.
8. Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Yulug B, Kilic U, Hermann DM, Kilic E (2015) “Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation”. Oncotarget 6:30604-30614. doi: 10.18632/oncotarget.5773.
9. Kilic E, Reitmeir R, Kilic U, Caglayan AB, Beker MC, Kelestemur T, Ethemoglu MS, Ozturk G, Hermann DM (2014) “HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia”. Frontiers in cellular neuroscience 8:422. doi: 10.3389/fncel.2014.00422.

Uluslararası hakemli konferans/sempozyumların bildiri kitaplarında yer alan yayınlar

1. Poster- Beker MC, Caglayan AB, Yalcin E, Kilic U, Baykal AT, Gurel B, Kilic E, “Proteomic Approach To Circadian Rhythm After Brain Injury”, 7th EMBO Meeting, Germany, 2016.
2. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Sarma M, Kilic E, “The role of cerebral dopamine neurotrophic factor (CDNF) in the development of brain plasticity and repair: Role of axonal outgrowth inhibitors and cell signaling”, 7th EMBO Meeting, Germany, 2016.
3. Poster- Caglayan B, Caglayan AB, Beker MC, Kilic U, Yalcin E, Altunay S, Kelestemur T, Gunal MY, Hanoglu L, Yulug B, Kilic E, “Repetitive transcranial magnetic stimulation promotes neuronal survival in the acute phase and stroke- recovery in the sub-acute phase of focal cerebral ischemia” 7th EMBO Meeting, Germany, 2016.
4. Poster- Kilic U, Caglayan AB, Beker MC, Elibol B, Beker M, Altug-Tasa B, Ozcicek I, Ozen M, Yilmaz B, Kilic E, “Melatonin Promotes Stroke Recovery By Stimulating Axonal Projections And Neurogenesis”, 7th EMBO Meeting, Germany, 2016.
5. Poster- Yalcin E, Caglayan AB, Beker MC, Gurel B, Kelestemur T, Caglayan B, Dalay A, Dilden A, Altunay S, Sertel E, Yulug B, Kilic U, Kilic E, “Oatp1a5 transporter is a gateway for pharmacological compounds to the ischemic brain” 7th EMBO Meeting, Germany, 2016.
6. Poster- Kilic U, Beker MC, Caglayan AB, Elibol B, Karakas M, Altug B, Gok O, Kelestemur T, Kilic E, “Melatonin promotes neurological recovery, peri-lesional tissue remodeling, and contralesional pyramidal tract plasticity after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
7. Poster- Kelestemur T, Caglayan AB, Beker MC, Kilic U, Altunay S, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E, “Effects of normobaric oxygen treatment on brain injury after hypoxia-ischemia in newborn mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
8. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Ozturk G, Kilic E “The role of neuronal expression of P2X7 receptors in the processes of brain injury in mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
9. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “Inhibition but not activation of P2X7 receptors improves brain epileptiform activity in mice: Role of iNOS activation” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
10. Poster- Beker MC, Caglayan AB Kelestemur T, Yalcin E, Ozturk G, Kilic E, “Roles of oxygen treatment in the development of ischemic brain injury, signal transduction and brain microcirculation after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
11. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “The phosphatidylinositol-3 kinase/Akt pathway mediates melatonin’s neuroprotective activity after focal cerebral ischemia” The 5th EMBO Meeting, 2013.
12. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Gundogdu RZ, Kilic E “Roles of P2X7 receptors in neuronal injury after optic nerve transaction and focal cerebral ischemia” The 5th EMBO Meeting, 2013.

Ulusal hakemli konferans/sempozyumların bildiri kitaplarında yer alan yayınlar

1. Sözlü Sunum- Keleştemur T, Çağlayan AB, Beker MC, Çağlayan B, Yalçın E, Sertel E, Kılıç E, “Beyin Felci Sonrası Gelişen Patofizyolojik Süreçlerin İleri Mikroskopi Teknikleri ile İncelenmesi” 15. Ulusal Sinirbilim Kongresi, Sakarya, 2017.
2. Sözlü Sunum- Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Dalay A, Altunay A, Sertel E, Kilic E, “Effects of Circadian Rhythm on Brain Injury and Related Molecular Mechanisms” 42. Ulusal Fizyoloji Kongresi, 20/32, Düzce, 2016.
3. Sözlü Sunum- Kelestemur T, Beker MC, Caglayan AB, Yalcin E, Altunay S, Dalay A, Sertel E, Dilden A, Caglayan B, Kilic E, “Role of Normobaric Oxygen Treatment on Newborn Hypoxia –Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, OC23, Düzce/ Turkey, 2016.
4. Poster- Yalcin E, Caglayan AB, Beker MC, Kelestemur T, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kilic E, “The role of solute carrier Oatp1a4 in brain injury pharmacotherapy” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress , PC108, Düzce/Turkey, 2016.
5. Poster- Kilic U, Elibol B, Beker MC, Caglayan AB, Tasa-Altug B, Beker M, Ozen B, Yilmaz B, Kilic E, “Plasticity-Promoting Effect of Melatonin After Experimental Cerebral Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC112, Düzce/Turkey, 2016.
6. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Saarma M, Kilic E, “Effect of Neurotrophic factors CDNF and MANF Brain Plasticity and Repair After Brain Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC118, Düzce/ Turkey, 2016.
7. Sözlü Sunum- Caglayan AB, Yalcin E, Beker MC, Caglayan B, Kelestemur T, Ozturk G, Kilic E “In vivo ve in vitro P2X7 receptörü aracılı nöronal sağkalım mekanizması” 13. Ulusal Sinirbilim Kongresi, 2015.
8. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptörünün farede epilepsi sonrası rolü” 13. Ulusal Sinirbilim Kongresi, 2015.
9. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Caglayan B, Kilic E “Melatonin ve normobarik oksijen tedavisinin reperfüzyon hasarına etkileri” 13. Ulusal Sinirbilim Kongresi, 2015.
10. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptör baskılanması ve aktivasyonunun beyin epileptiform aktivitesi, mikrodolaşımı ve hücre içi sinyal iletim molekülleri üzerine olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014.
11. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Ozturk G, Kilic E “Normobarik oksijen tedavisinin beyin felci sonrası gelişen hasar, sinyal mekanizmaları ve beyin kan dolaşımına olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014
12. Sözlü sunum- Kilic U, Gok O, Karakas M, Elibol B, Beker MC, Caglayan AB, Kilic E “İskemi sonrası fonksiyonel iyileşmeyi sağlayan plastisiteye bağlı moleküler mekanizmalarda melatoninin etkinliğinin araştırılması” 40. Ulusal Fizyoloji Kongresi, 2014.
13. Sözlü sunum- Kelestemur T, Caglayan AB, Beker MC, Yilmaz B, Kilic E “Sıçanlarda memantin ve melatonin tedavisinin travmatik beyin hasarı sonrası etkilerinin araştırılması” 11. Ulusal Sinirbilim Kongresi, 2013.
14. Poster- Caglayan AB, Beker MC, Kilic E, Kilic U “P2X7 reseptörlerinin fare optik kesisi ve fokal iskemi modelleriyle oluşturulan nöronal hasar üzerine etkisi” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
15. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “Fosfatidil inozitol-3 kinaz/AKT sinyal yolağının Melatoninin iskemi sonrası nöroprotektif etkisinde rolü” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
16. Sözlü sunum- Seker FB, Kilic U, Caglayan AB, Ekimci N, Cevreli B, Beker MC, Demirci S, Dogan A, Yilmaz B, Kilic E “Profiklaktik olarak uygulanan 3-Hidroksi-3-Metilglutaril Koenzim A Redüktaz İnhibitörlerinin penisilinle indüklenen beyin epileptik aktivitesine etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.
17. Sözlü-sunum- Kilic U, Caglayan B, Ethemoglu, Caglayan AB, Beker MC, Ekimci N, Kilic E “3-Hydroxy-Methykgkutaryl Coenzyme A reductase inhibitörü rosuvastatinin beyin felci sonrası beyin plastisitesi ve onarım üzerine olan etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.






text
Adı Soyadı Dr.Öğr.Üye. Ahmet Burak ÇAĞLAYAN
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Yeditepe Üniversitesi 2011 Sinirbilim / İstanbul Medipol Üniversitesi

Daha Önce Görev Yaptığı Yerler

Yeditepe Üniversitesi, Bezmialem Vakıf Üniversitesi

Araştırma Alanları

Beyin Felci sonrası Plastisite ve Fonksiyonel Geri Kazanım

Seçili Yayınları / Tüm Yayınları

Uluslararası Yayınlar
1: Beker MC, Caglayan B, Caglayan AB, Kelestemur T, Yalcin E, Caglayan A, Kilic U, Baykal AT, Reiter RJ, Kilic E. Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival. Sci Rep. 2019 Dec 13;9(1):19082. doi: 10.1038/s41598-019-55663-0. PubMed PMID: 31836786; PubMed Central PMCID: PMC6910929.

2: Kelestemur T, Beker MC, Caglayan AB, Caglayan B, Altunay S, Kutlu S, Kilic E. Normobaric oxygen treatment improves neuronal survival functional recovery and axonal plasticity after newborn hypoxia-ischemia. Behav Brain Res. 2020 Feb 3;379:112338. doi: 10.1016/j.bbr.2019.112338. Epub 2019 Nov 13. PubMed PMID: 31733311.

3: Yalcin E, Beker MC, Turkseven S, Caglayan B, Gurel B, Kilic U, Caglayan AB, Kalkan R, Baykal AT, Kelestemur T, Kilic E. Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival. Toxicol Appl Pharmacol. 2019 Sep 15;379:114686. doi: 10.1016/j.taap.2019.114686. Epub 2019 Jul 17. PubMed PMID: 31325559.

4: Caglayan AB, Beker MC, Caglayan B, Yalcin E, Caglayan A, Yulug B, Hanoglu L, Kutlu S, Doeppner TR, Hermann DM, Kilic E. Acute and Post-acute Neuromodulation Induces Stroke Recovery by Promoting Survival Signaling, Neurogenesis, and Pyramidal Tract Plasticity. Front Cell Neurosci. 2019 Apr 12;13:144. doi: 10.3389/fncel.2019.00144. eCollection 2019. PubMed PMID: 31031599; PubMed Central PMCID: PMC6474396.

5: Caglayan B, Caglayan AB, Beker MC, Yalcin E, Beker M, Kelestemur T, Sertel E, Ozturk G, Kilic U, Sahin F, Kilic E. Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice. Exp Neurol. 2017 Oct;296:23-31. doi: 10.1016/j.expneurol.2017.06.024. Epub 2017 Jun 29. PubMed PMID: 28669743.

6: Demirci S, Doğan A, Başak Türkmen N, Telci D, Çağlayan AB, Beker MÇ, Kiliç E, Özkan F, Dede B, Şahin F. Poloxamer P85 increases anticancer activity of Schiff base against prostate cancer in vitro and in vivo. Anticancer Drugs. 2017 Sep;28(8):869-879. doi: 10.1097/CAD.0000000000000528. PubMed PMID: 28614092.

7: Beker MC, Caglayan B, Yalcin E, Caglayan AB, Turkseven S, Gurel B, Kelestemur T, Sertel E, Sahin Z, Kutlu S, Kilic U, Baykal AT, Kilic E. Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT. Mol Neurobiol. 2018 Mar;55(3):2565-2576. doi: 10.1007/s12035-017-0524-4. Epub 2017 Apr 18. PubMed PMID: 28421530.

8: Kilic U, Caglayan AB, Beker MC, Gunal MY, Caglayan B, Yalcin E, Kelestemur T, Gundogdu RZ, Yulug B, Yılmaz B, Kerman BE, Kilic E. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol. 2017 Aug;12:657-665. doi: 10.1016/j.redox.2017.04.006. Epub 2017 Apr 5. PubMed PMID: 28395173; PubMed Central PMCID: PMC5388917.

9: Doğan A, Demirci S, Türkmen NB, Çağlayan AB, Aydın S, Telci D, Kılıç E, Şahin K, Orhan C, Tuzcu M, Ekici AI, Şahin F. Schiff Base-Poloxamer P85 Combination Prevents Prostate Cancer Progression in C57/Bl6 Mice. Prostate. 2016 Nov;76(15):1454-63. doi: 10.1002/pros.23229. Epub 2016 Jun 24. PubMed PMID: 27338565.

10: Doeppner TR, Kaltwasser B, Sanchez-Mendoza EH, Caglayan AB, Bähr M, Hermann DM. Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3ß inhibition-independent pathways. J Cereb Blood Flow Metab. 2017 Mar;37(3):914-926. doi: 10.1177/0271678X16647738. Epub 2016 Jul 21. Erratum in: J Cereb Blood Flow Metab. 2018 Oct;38(10):1850. PubMed PMID: 27126323; PubMed Central PMCID: PMC5363471.

11: Kartal Ö, Aydınöz S, Kartal AT, Kelestemur T, Caglayan AB, Beker MC, Karademir F, Süleymanoğlu S, Kul M, Yulug B, Kilic E. Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3. Metab Brain Dis. 2016 Aug;31(4):827-35. doi: 10.1007/s11011-016-9816-z. Epub 2016 Mar 4. PubMed PMID: 26943480.

12: Kelestemur T, Yulug B, Caglayan AB, Beker MC, Kilic U, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E. Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine. Neurosci Lett. 2016 Jan 26;612:92-97. doi: 10.1016/j.neulet.2015.11.043. Epub 2015 Nov 27. PubMed PMID: 26639427.

13: Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Yulug B, Kilic U, Hermann DM, Kilic E. Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation. Oncotarget. 2015 Oct 13;6(31):30604-14. doi: 10.18632/oncotarget.5773. PubMed PMID: 26416428; PubMed Central PMCID: PMC4741555.

14: Hermann DM, Zechariah A, Kaltwasser B, Bosche B, Caglayan AB, Kilic E, Doeppner TR. Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia. Neurobiol Dis. 2015 Nov;83:16-25. doi: 10.1016/j.nbd.2015.08.018. Epub 2015 Aug 24. PubMed PMID: 26316359.

15: Kilic E, Reitmeir R, Kilic Ü, Caglayan AB, Beker MC, Kelestemur T, Ethemoglu MS, Ozturk G, Hermann DM. HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia. Front Cell Neurosci. 2014 Dec 11;8:422. doi: 10.3389/fncel.2014.00422. eCollection 2014. PubMed PMID: 25565957; PubMed Central PMCID: PMC4263103.

16: Seker FB, Kilic U, Caglayan B, Ethemoglu MS, Caglayan AB, Ekimci N, Demirci S, Dogan A, Oztezcan S, Sahin F, Yilmaz B, Kilic E. HMG-CoA reductase inhibitor rosuvastatin improves abnormal brain electrical activity via mechanisms involving eNOS. Neuroscience. 2015 Jan 22;284:349-59. doi: 10.1016/j.neuroscience.2014.10.014. Epub 2014 Oct 19. PubMed PMID: 25453767.


17: Doğan A, Demirci S, Cağlayan AB, Kılıç E, Günal MY, Uslu U, Cumbul A, Sahin F. Sodium pentaborate pentahydrate and pluronic containing hydrogel increases cutaneous wound healing in vitro and in vivo. Biol Trace Elem Res. 2014 Dec;162(1-3):72-9. doi: 10.1007/s12011-014-0104-7. Epub 2014 Aug 17. PubMed PMID: 25129136.


Özetler
Uluslararası Bildiriler
1. Poster- Beker MC, Caglayan AB, Yalcin E, Kilic U, Baykal AT, Gurel B, Kilic E, “Proteomic Approach To Circadian Rhythm After Brain Injury”, 7th EMBO Meeting, Germany, 2016.
2. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Sarma M, Kilic E, “The role of cerebral dopamine neurotrophic factor (CDNF) in the development of brain plasticity and repair: Role of axonal outgrowth inhibitors and cell signaling”, 7th EMBO Meeting, Germany, 2016.
3. Poster- Caglayan B, Caglayan AB, Beker MC, Kilic U, Yalcin E, Altunay S, Kelestemur T, Gunal MY, Hanoglu L, Yulug B, Kilic E, “Repetitive transcranial magnetic stimulation promotes neuronal survival in the acute phase and stroke- recovery in the sub-acute phase of focal cerebral ischemia” 7th EMBO Meeting, Germany, 2016.
4. Poster- Kilic U, Caglayan AB, Beker MC, Elibol B, Beker M, Altug-Tasa B, Ozcicek I, Ozen M, Yilmaz B, Kilic E, “Melatonin Promotes Stroke Recovery By Stimulating Axonal Projections And Neurogenesis”, 7th EMBO Meeting, Germany, 2016.
5. Poster- Yalcin E, Caglayan AB, Beker MC, Gurel B, Kelestemur T, Caglayan B, Dalay A, Dilden A, Altunay S, Sertel E, Yulug B, Kilic U, Kilic E, “Oatp1a5 transporter is a gateway for pharmacological compounds to the ischemic brain” 7th EMBO Meeting, Germany, 2016.
6. Poster- Kilic U, Beker MC, Caglayan AB, Elibol B, Karakas M, Altug B, Gok O, Kelestemur T, Kilic E, “Melatonin promotes neurological recovery, peri-lesional tissue remodeling, and contralesional pyramidal tract plasticity after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
7. Poster- Kelestemur T, Caglayan AB, Beker MC, Kilic U, Altunay S, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E, “Effects of normobaric oxygen treatment on brain injury after hypoxia-ischemia in newborn mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
8. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Ozturk G, Kilic E “The role of neuronal expression of P2X7 receptors in the processes of brain injury in mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
9. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “Inhibition but not activation of P2X7 receptors improves brain epileptiform activity in mice: Role of iNOS activation” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
10. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Ozturk G, Kilic E, “Roles of oxygen treatment in the development of ischemic brain injury, signal transduction and brain microcirculation after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
11. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “The phosphatidylinositol-3 kinase/Akt pathway mediates melatonin’s neuroprotective activity after focal cerebral ischemia” The 5th EMBO Meeting, 2013.
12. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Gundogdu RZ, Kilic E “Roles of P2X7 receptors in neuronal injury after optic nerve transaction and focal cerebral ischemia” The 5th EMBO Meeting, 2013.

Ulusal Bildiriler ve Sözlü Sunumlar
1. Poster- Kelestemur T, Caglayan AB, Beker MC, Caglayan B, Yalcin E, Sertel E, Kilic E “Investigation of Pathophysiological Processes with Advanced Microscopy Techniques after Cerebral Ischemia” 15. Ulusal Sinirbilim Kongresi, Sakarya, 2017.
2. Sözlü Sunum- Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Dalay A, Altunay A, Sertel E, Kilic E, “Effects of Circadian Rhythm on Brain Injury and Related Molecular Mechanisms” 42. Ulusal Fizyoloji Kongresi, 20/32, Düzce, 2016.
3. Sözlü Sunum- Kelestemur T, Beker MC, Caglayan AB, Yalcin E, Altunay S, Dalay A, Sertel E, Dilden A, Caglayan B, Kilic E, “Role of Normobaric Oxygen Treatment on Newborn Hypoxia –Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, OC23, Düzce/ Turkey, 2016.
4. Poster- Yalcin E, Caglayan AB, Beker MC, Kelestemur T, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kilic E, “The role of solute carrier Oatp1a4 in brain injury pharmacotherapy” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress , PC108, Düzce/Turkey, 2016.
5. Poster- Kilic U, Elibol B, Beker MC, Caglayan AB, Tasa-Altug B, Beker M, Ozen B, Yilmaz B, Kilic E, “Plasticity-Promoting Effect of Melatonin After Experimental Cerebral Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC112, Düzce/Turkey, 2016.
6. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Saarma M, Kilic E, “Effect of Neurotrophic factors CDNF and MANF Brain Plasticity and Repair After Brain Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC118, Düzce/ Turkey, 2016
7. Sözlü Sunum- Caglayan AB, Yalcin E, Beker MC, Caglayan B, Kelestemur T, Ozturk G, Kilic E “In vivo ve in vitro P2X7 receptörü aracılı nöronal sağkalım mekanizması” 13. Ulusal Sinirbilim Kongresi, 2015.
8. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptörünün farede epilepsi sonrası rolü” 13. Ulusal Sinirbilim Kongresi, 2015.
9. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Caglayan B, Kilic E “Melatonin ve normobarik oksijen tedavisinin reperfüzyon hasarına etkileri” 13. Ulusal Sinirbilim Kongresi, 2015.
10. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptör baskılanması ve aktivasyonunun beyin epileptiform aktivitesi, mikrodolaşımı ve hücre içi sinyal iletim molekülleri üzerine olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014.
11. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Ozturk G, Kilic E “Normobarik oksijen tedavisinin beyin felci sonrası gelişen hasar, sinyal mekanizmaları ve beyin kan dolaşımına olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014
12. Sözlü sunum- Kilic U, Gok O, Karakas M, Elibol B, Beker MC, Caglayan AB, Kilic E “İskemi sonrası fonksiyonel iyileşmeyi sağlayan plastisiteye bağlı moleküler mekanizmalarda melatoninin etkinliğinin araştırılması” 40. Ulusal Fizyoloji Kongresi, 2014.
13. Sözlü sunum- Kelestemur T, Caglayan AB, Beker MC, Yilmaz B, Kilic E “Sıçanlarda memantin ve melatonin tedavisinin travmatik beyin hasarı sonrası etkilerinin araştırılması” 11. Ulusal Sinirbilim Kongresi, 2013.
14. Poster- Caglayan AB, Beker MC, Kilic E, Kilic U “P2X7 reseptörlerinin fare optik kesisi ve fokal iskemi modelleriyle oluşturulan nöronal hasar üzerine etkisi” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
15. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “Fosfatidil inozitol-3 kinaz/AKT sinyal yolağının Melatoninin iskemi sonrası nöroprotektif etkisinde rolü” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
16. Sözlü sunum- Seker FB, Kilic U, Caglayan AB, Ekimci N, Cevreli B, Beker MC, Demirci S, Dogan A, Yilmaz B, Kilic E “Profiklaktik olarak uygulanan 3-Hidroksi-3-Metilglutaril Koenzim A Redüktaz İnhibitörlerinin penisilinle indüklenen beyin epileptik aktivitesine etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.
17. Sözlü-sunum- Kilic U, Caglayan B, Ethemoglu, Caglayan AB, Beker MC, Ekimci N, Kilic E “3-Hydroxy-Methykgkutaryl Coenzyme A reductase inhibitörü rosuvastatinin beyin felci sonrası beyin plastisitesi ve onarım üzerine olan etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.

text
Adı Soyadı Dr.Öğr.Üye. Ayşe Arzu ŞAKUL
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Ondokuzmayıs Üniversitesi 1994 Hacettepe Üniversitesi Tıp Fakültesi & Gazi Üniversitesi Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

Sağlık Bakanlığı-Acil Sağlık Hizmetleri Genel Müdürlüğü- Afet ve Acil Durum Daire Başkanlığı- Ulusal Zehir Merkezi Koordinatörü

Araştırma Alanları

Diabetes Mellitus, oksidatif ve nitrozatif stres, senescence ve rejenerasyon, bağımlılık farmakolojisi, klinik toksikoloji, klinik farmakoloji, nörofarmakoloji

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Dr.Öğr.Üye. Nihal KARAKAŞ
E-Posta [email protected]
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi Deneysel Tıp Araştırma Enstitüsü ve Harvard Tıp Fakültesi, Massachusetts General Hospital

Daha Önce Görev Yaptığı Yerler

Molecular Neurotherapy and Imaging Laboratory (MNIL), Massachusetts General Hospital, Harvard Medical School ve University of Edinburgh, Center for Regenerative Medicine, Adult Cell Therapy Group

Araştırma Alanları

In cancer therapy, toxicity in healthy tissue is a common side effect of current treatment modalities and tumor recurrence is almost inevitable. There is therefore an urgent need to develop novel therapies that act in a robust and cancer-selective manner. In line with this, main focus of our research is developing novel targeting therapy approaches for cancer treatment. One of the succesfull delivery strategy for targeted therapeutics without the limitations of current chemotherapeutic agents, is using stem cells as therapeutic cargo carriers since they have known with their migration capacity towards the tumor sites even including microdeposits. Furthermore, stem cells can be collected individually and engineered to secrete therapeutics which can enable their clinical translation from bench side to bed side. Recently, we are working on engineering stem cells to secrete anti-cancer therapeutics including targeted toxins for the treatment of high grade gliomas and other malignancies. For this aim, we combine bioimaging markers (fluorescence proteins and firefly luciferases) and therapeutic molecules in stem cells using lentiviral vectors. Following pre- and post-implantation of these therapeutically engineered stem cell cargos in mice bearing bioimagable tumors, we then analyse tumor regression by fluorescence/bioluminescence imaging tools and subsequent tissue processing. Furthermore, we investigate the molecular mechanism leading to cancer cell death in culture and to loss in tumor mass in treated mice upon therapeutic stem cell implantation. We study in a close collaboration with Dr. Shah who is the head of Center for Stem Cell Therapeutics and Imaging, Brigham and Woman's Hospital, Harvard Medical School in Boston, U.S. Selected media attentions: - Cancer-killing stem cells engineered in lab (BBC News, October 24, 2014) - Stem cells that can kill cancer have been engineered by scientists (The Independent, October 27, 2014) - Toxin-Secreting Stem Cells May Destroy Brain Tumors From Inside Out (Popular Science, October 27, 2014)

Seçili Yayınları / Tüm Yayınları

• Stuckey DW*, Hingtgen S*, Karakas N, Rich B, Shah K. “Engineering toxin-resistant therapeutic
stem cells to treat brain tumors”, Stem Cells, (Oct. 2014) *authors equally contributed.
• Karakas N, Stuckey DW, Choi SH, Shah K. “ Arming stem cells with targeted toxins breaks
resistance and potentiates TRAIL killing of brain tumors” (in submission)
• Karakas N, Shah K. “Stem Cell Delivery of Targeted Toxins for GBM Therapy (Review)” (in
preperation)
• Isik S, Zaim M, Yildiz MT, Negis Y, Kunduraci T, Karakas N, Arikan G, Cetin G. “DNA
topoisomerase IIß as a molecular switch in neural differentiation of mesenchymal stem cells”,
Annals of Hematology, Sept. 2014
• Mammadov B, Karakas N, Isik S. "Comparison of Long-term Retinoic Acid Based Neural Induction
Methods of Bone Marrow Human Mesenchymal Stem Cells", In vitro Cellular & Developmental
Biology , May 2011
• Kamaci N, Emnacar T, Karakas N, Arikan G, Tsutsui K, Isik. "Selective silencing of DNA
topoisomerase IIß in human mesenchymal stem cells by small interfering RNAs (siRNAs)", Cell
Biology International Reports, March 2011
• Karakas N, Mammadov B, Isik S, "Involvement of Integrin ?5ß1 in Neural Transdifferentiation of
Human Bone Marrow Derived Mesenchymal Stem Cells " (Abstract), Journal of IUBMB Life, May.
2009
• Mammadov B, Karakas N, Isik S, "Emphasis of the Efficient In Vitro Neurogenesis Method For
Bone Marrow Derived Human Mesenchymal Stem Cells" (Abstract), Journal of IUBMB Life, May
2009


Selected media attentions:
- Cancer-killing stem cells engineered in lab (BBC News, October 24, 2014)
- Stem cells that can kill cancer have been engineered by scientists (The Independent, October 27, 2014)
- Toxin-Secreting Stem Cells May Destroy Brain Tumors From Inside Out (Popular Science, October 27, 2014)

text
Adı Soyadı Dr.Öğr.Üye. Elif Zeynep YILMAZ
E-Posta [email protected]
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi 1997 İstanbul Üniversitesi Onkoloji Enstitüsü Kanser Biyokimyası

Daha Önce Görev Yaptığı Yerler

İstanbul Üniversitesi Onkoloji Enstitüsü

Araştırma Alanları

Moleküler Onkoloji, Meme Kanseri, Kolorektal Kanser ve Löseminin Moleküler Biyolojisi

Seçili Yayınları / Tüm Yayınları

ULUSLARARASI YAYINLAR
1- Eralp Y, Keskin S, Akışık E, Akışık E, İğci A, Müslümanoğlu M, Yılmaz S, Tunacı M, Çamlıca H, Tuzlalı S, Saip P, Dalay N, Özmen V, Topuz E.
Predictive role of midtreatment changes in survivin, GSTP1, and topoisomerase 2? expressions for pathologic complete response to neoadjuvant chemotherapy in patients with locally advanced breast cancer.
Am J Clin Oncol. 2013 Jun;36(3):215-23.

2- Akisik E, Buğra D, Yamaner S, Dalay N.
Analysis of ß-catenin alterations in colon tumors: a novel exon 3 mutation.
Tumour Biol. 2011; 32(1):71-6.

3- Akisik E., Yazici H, Dalay N.
ARLTS1, MDM2 and RAD51 gene variations are associated with familial breast cancer. Mol Biol Rep. 2011; 38(1):343-8.

4 - Yazici H, Zipprich J, Peng T, Akisik E.Z, Tigli H, Isin M, Akisik EE, Terry MB, Senie RT, Li L, Peng M, Liu Z, Dalay N and Santella RM.
Investigation of the miR16-1 (C>T)+7 substitution in six different types of cancer from three ethnic groups.
J Oncol. 2009; 2009: 1-4.

5- Deligezer U, Eralp Y, Akisik EZ, Akisik EE, Saip P, Topuz E, Dalay N.
Effect of adjuvant chemotherapy on integrity of free serum DNA in patients with breast cancer.
Ann N Y Acad Sci. 2008; 1137: 175-9.

6 - Deligezer U, Eralp Y, Akisik EE, Akisik EZ, Saip P, Topuz E, Dalay N.
Size distribution of circulating cell-free DNA in sera of breast cancer patients in the course of adjuvant chemotherapy.
Clin Chem Lab Med. 2008; 46 (3): 311-7.

7 - Akisik E, Dalay N.
Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer.
J Clin Lab Anal 2007; 21:97–102.

8 - Akisik E, Dalay N.
Estrogen receptor codon 594 and HER2 codon 655 polymorphisms and breast cancer risk.
Exp Mol Pathol 2004; 76 (3): 260-263.

9 - Akisik E, Bavbek S, Dalay N.
CD44 variant exons in leukemia and lymphoma
Pathol Oncol Res 2002; 8; 1: 36-40.

10 - Yazici H, Bitisik O, Akisik E, Cabioglu N, Saip P, Muslumanoglu M, Glendon G, Bengisu E, Ozbilen S, Dincer M, Turkmen S, Andrulis IL, Dalay N, Ozcelik H.
BRCA1 and BRCA2 mutations in Turkish breast/ovarian families and young breast cancer patients.
Br J Cancer 2000; 83 (6): 737-742.

ULUSAL YAYINLAR
1 - Elif Zeynep Akışık, Nejat Dalay.
Kolon, Rektum ve Anal Kanserlerin Moleküler Biyolojisi.
Klinik Laboratuvar Cilt 3, Sayı-1-2, Ocak-Haziran 2004, 1-9.

KİTAP BÖLÜMLERİ
1- Ugur Deligezer, Elif Z. Akisik, Ebru E. Akisik, Müge Kovancilar, Dursun Bugra, Nilgün Erten, Stefan Holdenrieder, Nejat Dalay. İçinde Peter B. Gahan, editör. Circulating Nucleic Acids in Plasma and Serum. Dordrecht Heidelberg London New York Springer., 2011. pp. 97-103.

text
Adı Soyadı Dr.Öğr.Üye. Akif AYAZ
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

text
Adı Soyadı Dr.Öğr.Üye. Salih GENCER
E-Posta [email protected]
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

Kurum Dışı Görevlendirme