Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ANALYTICAL CHEMISTRY LAB II | - | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Ümit Can ERİM |
| Name of Lecturer(s) | Assist.Prof. Ümit Can ERİM, Prof.Dr. Ali Osman AYDIN |
| Assistant(s) | Res. Assist. Nursu Aylin KASA, Res. Assist.Mehmet Enes TEZÇAKAR, Öğr. Gör. Büşra ŞAHİNKURT |
| Aim | As being a part of quantitative chemical analysis methods, to teach principles of gravimetric and volumetric analysis methods and apply them in the laboratory. To teach various instrumental analysis methods used in quantitative analysis and to perform those skills in the laboratory. |
| Course Content | This course contains; Gravimetric analysis and determination of sulphate,Acid-base titrations; preparation of standard solution and determination of sodium hydroxide,Preparation of standard solution and determination of hydrochloric acid,Determination of carbonate and bicarbonate mix,Precipitation titrations; determination of chloride by AgNO3 solution,Complexometric titrations; determination of calcium and magnesium by EDTA solution.,Oxidation-reduction titrations; determination of H2O2 by permanganate solution.,Determination of copper (iodometrically) by sodium thiosulfate solution,Potantiometric titration,Determination of caffeine and paracetamol in the pain-breakers by ultraviolet (UV) spectrometer,Determination of organic compounds with IR spectrometry,High pressure liquid chromatography applications,Determination of the ratios of fatty acid of various oils by gas chromatography (GC),Compensatory week. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Students will be able to discuss the stoichiometry of application methods and the principles of gravimetric analysis. | 12, 14, 16, 17, 9 | A, D, E, G, H |
| 1.1. Interprets the gravimetric sulfate analysis and similar analysis | 12, 14, 16, 17, 9 | A, D, E, G, H |
| 1.2. Explains the stoichiometry of gravimetric analysis. | 12, 14, 16, 17, 9 | A, D, E, G, H |
| 2. To be able to discuss the principles and application methods of volumetric analysis. | 12, 14, 17, 9 | A, D, E, G, H |
| 2.1. Explains the preparation and calibration of the standard solution. | 12, 14, 17, 9 | A, D, E, G, H |
| 2.2. Interprets the determination of volumetric acid and base. | 12, 14, 17, 9 | A, D, E, G, H |
| 2.3. Explains the analysis of carbonate and bicarbonate. | 12, 14, 17, 9 | A, D, E, G, H |
| 3. To be able to discuss the application methods and principles of precipitation titrations. | 12, 14, 17, 9 | A, D, E, G, H |
| 3.1. Interprets the argentometric chloride determination. | 12, 14, 17, 9 | A, D, E, G, H |
| 4. To be able to discuss the application methods and principles of complexometric titrations. | 12, 14, 17, 9 | A, D, E, G, H |
| 4.1. Explains the analysis of calcium and magnesium by EDTA. | 12, 14, 17, 9 | A, D, E, G, H |
| 5. To be able to discuss the application methods and principles of oxidation-reduction titrations. | 12, 14, 17, 9 | A, D, E, G, H |
| 5.1. Explains the determination of H2O2 by permanganate solution. | 12, 14, 17, 9 | A, D, E, G, H |
| 5.2. Interprets the determination of copper by sodium thiosulfate solution. | 12, 14, 17, 9 | A, D, E, G, H |
| 6. Discusses the principles and application methods of potentiometric titration. | 12, 14, 17, 9 | A, D, E, G, H |
| 7. To be able to discuss the application methods and principles of analysis methods by ultraviolet (UV) spectrometer. | 12, 14, 17, 9 | A, D, E, G, H |
| 7.1. Explains the determination of aspirin and caffeine by UV spectrometer. | 11, 12, 14, 17, 9 | A, D, E, G |
| 8. To be able to discuss the application methods and principles of applications of IR spectrometer in the analysis. | 11, 12, 16, 17, 9 | A, D, E, G |
| 9. Discusses the basis and application methods of chromatographic analysis methods. | 11, 12, 16, 17, 9 | A, D, E, G |
| 9.1. Analyzes with high pressure liquid chromatography | 11, 12, 16, 17, 9 | A, D, E, G |
| 9.2. Determines the fatty acid ratios of various oils by gas chromatography | 11, 12, 16, 17, 9 | A, D, E, G |
| Teaching Methods: | 11: Demonstration Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz, H: Performance Task |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Gravimetric analysis and determination of sulphate | 1 |
| 2 | Acid-base titrations; preparation of standard solution and determination of sodium hydroxide | 1 |
| 3 | Preparation of standard solution and determination of hydrochloric acid | 1 |
| 4 | Determination of carbonate and bicarbonate mix | 1 |
| 5 | Precipitation titrations; determination of chloride by AgNO3 solution | 1 |
| 6 | Complexometric titrations; determination of calcium and magnesium by EDTA solution. | 1 |
| 7 | Oxidation-reduction titrations; determination of H2O2 by permanganate solution. | 1 |
| 8 | Determination of copper (iodometrically) by sodium thiosulfate solution | 1 |
| 9 | Potantiometric titration | 1 |
| 10 | Determination of caffeine and paracetamol in the pain-breakers by ultraviolet (UV) spectrometer | 1 |
| 11 | Determination of organic compounds with IR spectrometry | 1 |
| 12 | High pressure liquid chromatography applications | 1 |
| 13 | Determination of the ratios of fatty acid of various oils by gas chromatography (GC) | 1 |
| 14 | Compensatory week | 1 |
| Resources |
| [1] Aydın, A. O., Analitik Kimya Lab.- II Ders Notu, Sakarya, 2010. [2]. Dündar, M. Ş., Enstrümantal Analiz Lab. Deney Kitabı, Sakarya, 2008. [3] Gündüz, T, Kantitatif Analiz Laboratuvar Kitabı Gazi Kitabevi, Ankara, 2005. [4]. Kılıç, E., Köseoğlu, F., Yılmaz, H., (Çeviri editörleri), Enstrümantal Analiz İlkeleri, Skoog-Holler-Nieman, Bilim yayıncılık, Ankara, 2000. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 0 | 1 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 14 | 1 | 14 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 5 | 1 | 5 | |||
| Midterm Exam | 1 | 10 | 10 | |||
| General Exam | 1 | 16 | 16 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 87 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(87/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ANALYTICAL CHEMISTRY LAB II | - | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Ümit Can ERİM |
| Name of Lecturer(s) | Assist.Prof. Ümit Can ERİM, Prof.Dr. Ali Osman AYDIN |
| Assistant(s) | Res. Assist. Nursu Aylin KASA, Res. Assist.Mehmet Enes TEZÇAKAR, Öğr. Gör. Büşra ŞAHİNKURT |
| Aim | As being a part of quantitative chemical analysis methods, to teach principles of gravimetric and volumetric analysis methods and apply them in the laboratory. To teach various instrumental analysis methods used in quantitative analysis and to perform those skills in the laboratory. |
| Course Content | This course contains; Gravimetric analysis and determination of sulphate,Acid-base titrations; preparation of standard solution and determination of sodium hydroxide,Preparation of standard solution and determination of hydrochloric acid,Determination of carbonate and bicarbonate mix,Precipitation titrations; determination of chloride by AgNO3 solution,Complexometric titrations; determination of calcium and magnesium by EDTA solution.,Oxidation-reduction titrations; determination of H2O2 by permanganate solution.,Determination of copper (iodometrically) by sodium thiosulfate solution,Potantiometric titration,Determination of caffeine and paracetamol in the pain-breakers by ultraviolet (UV) spectrometer,Determination of organic compounds with IR spectrometry,High pressure liquid chromatography applications,Determination of the ratios of fatty acid of various oils by gas chromatography (GC),Compensatory week. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Students will be able to discuss the stoichiometry of application methods and the principles of gravimetric analysis. | 12, 14, 16, 17, 9 | A, D, E, G, H |
| 1.1. Interprets the gravimetric sulfate analysis and similar analysis | 12, 14, 16, 17, 9 | A, D, E, G, H |
| 1.2. Explains the stoichiometry of gravimetric analysis. | 12, 14, 16, 17, 9 | A, D, E, G, H |
| 2. To be able to discuss the principles and application methods of volumetric analysis. | 12, 14, 17, 9 | A, D, E, G, H |
| 2.1. Explains the preparation and calibration of the standard solution. | 12, 14, 17, 9 | A, D, E, G, H |
| 2.2. Interprets the determination of volumetric acid and base. | 12, 14, 17, 9 | A, D, E, G, H |
| 2.3. Explains the analysis of carbonate and bicarbonate. | 12, 14, 17, 9 | A, D, E, G, H |
| 3. To be able to discuss the application methods and principles of precipitation titrations. | 12, 14, 17, 9 | A, D, E, G, H |
| 3.1. Interprets the argentometric chloride determination. | 12, 14, 17, 9 | A, D, E, G, H |
| 4. To be able to discuss the application methods and principles of complexometric titrations. | 12, 14, 17, 9 | A, D, E, G, H |
| 4.1. Explains the analysis of calcium and magnesium by EDTA. | 12, 14, 17, 9 | A, D, E, G, H |
| 5. To be able to discuss the application methods and principles of oxidation-reduction titrations. | 12, 14, 17, 9 | A, D, E, G, H |
| 5.1. Explains the determination of H2O2 by permanganate solution. | 12, 14, 17, 9 | A, D, E, G, H |
| 5.2. Interprets the determination of copper by sodium thiosulfate solution. | 12, 14, 17, 9 | A, D, E, G, H |
| 6. Discusses the principles and application methods of potentiometric titration. | 12, 14, 17, 9 | A, D, E, G, H |
| 7. To be able to discuss the application methods and principles of analysis methods by ultraviolet (UV) spectrometer. | 12, 14, 17, 9 | A, D, E, G, H |
| 7.1. Explains the determination of aspirin and caffeine by UV spectrometer. | 11, 12, 14, 17, 9 | A, D, E, G |
| 8. To be able to discuss the application methods and principles of applications of IR spectrometer in the analysis. | 11, 12, 16, 17, 9 | A, D, E, G |
| 9. Discusses the basis and application methods of chromatographic analysis methods. | 11, 12, 16, 17, 9 | A, D, E, G |
| 9.1. Analyzes with high pressure liquid chromatography | 11, 12, 16, 17, 9 | A, D, E, G |
| 9.2. Determines the fatty acid ratios of various oils by gas chromatography | 11, 12, 16, 17, 9 | A, D, E, G |
| Teaching Methods: | 11: Demonstration Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz, H: Performance Task |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Gravimetric analysis and determination of sulphate | 1 |
| 2 | Acid-base titrations; preparation of standard solution and determination of sodium hydroxide | 1 |
| 3 | Preparation of standard solution and determination of hydrochloric acid | 1 |
| 4 | Determination of carbonate and bicarbonate mix | 1 |
| 5 | Precipitation titrations; determination of chloride by AgNO3 solution | 1 |
| 6 | Complexometric titrations; determination of calcium and magnesium by EDTA solution. | 1 |
| 7 | Oxidation-reduction titrations; determination of H2O2 by permanganate solution. | 1 |
| 8 | Determination of copper (iodometrically) by sodium thiosulfate solution | 1 |
| 9 | Potantiometric titration | 1 |
| 10 | Determination of caffeine and paracetamol in the pain-breakers by ultraviolet (UV) spectrometer | 1 |
| 11 | Determination of organic compounds with IR spectrometry | 1 |
| 12 | High pressure liquid chromatography applications | 1 |
| 13 | Determination of the ratios of fatty acid of various oils by gas chromatography (GC) | 1 |
| 14 | Compensatory week | 1 |
| Resources |
| [1] Aydın, A. O., Analitik Kimya Lab.- II Ders Notu, Sakarya, 2010. [2]. Dündar, M. Ş., Enstrümantal Analiz Lab. Deney Kitabı, Sakarya, 2008. [3] Gündüz, T, Kantitatif Analiz Laboratuvar Kitabı Gazi Kitabevi, Ankara, 2005. [4]. Kılıç, E., Köseoğlu, F., Yılmaz, H., (Çeviri editörleri), Enstrümantal Analiz İlkeleri, Skoog-Holler-Nieman, Bilim yayıncılık, Ankara, 2000. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |