Assist.Prof. Mehmet Hikmet ÜÇIŞIK, Assoc.Prof. Özge ŞENSOY
Assistant(s)
Tissue and Genetic Engineering
Aim
Doku mühendisliği, vücuttaki hastalıklı veya yaralı doku ve organları yenilemeyi veya onarmayı amaçlayan bir alandır. Doku mühendisliği, biyoloji, kimya, malzeme bilimi, mühendislik, immünoloji ve transplantasyon gibi birçok farklı bilimi kapsar. Ders, doku büyümesi ve gelişimi ile doku ve organların tasarlanması için gerekli araç ve teorik bilgilerin genel bir anlayışını sağlar. Öğrencilere yönelik öğrenme yöntemi ve sömestir projesi, öğrencilere doku kavramlarını, ilkelerini ve uygulamalarını tanıtmak için öğretim aracı olarak kullanılacaktır.
Course Content
This course contains; Introductory Lecture,Introduction to Tissue Engineering ,How Genetic Engineering serves to Tissue Engineering ,Stem Cell Tissue Engineering ,Polymeric Scaffolds for Tissue Engineering Applications ,Fabrication Methods of Tissue Engineering Scaffolds,3D Organ Printing and Cell Encapsulation,Basics in Immunology and Immune Host Response to Biomaterials,Extracellular Matrix: Structure Function, and Application to Tissue Engineering,Microvascular Imaging Methods for Tissue Engineering,In Vitro & In Vivo Testing,Standards and Regulations in Tissue Engineering Applications: ISO, FDA etc.,Project Presentations,Selected Topics on Tissue Engineering.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
Describe the tissue engineering as a prominent approach composed of different disciplines
10, 13, 14, 37, 5, 9
A, F
Define the different strategies and approaches in tissue engineering
10, 14, 2, 5
A, F
Analyze, evaluate, describe and compare different experimental techniques in tissue engineering
10, 14, 5
A, F
Understand the experimental design of a tissue engineering study
10, 37, 4, 5
A, F
Get the ability to combine their personal knowledge in biology, material science, engineering and medicine to understand and address the challenges in tissue engineering
10, 18, 2, 5
A, F
Describe the national and universal standards for tissue engineering preclinic and clinic applications
10, 18, 2, 5
A, F
Teaching Methods:
10: Discussion Method, 13: Case Study Method, 14: Self Study Method, 18: Micro Teaching Technique, 2: Project Based Learning Model, 37: Computer-Internet Supported Instruction, 4: Inquiry-Based Learning, 5: Cooperative Learning, 9: Lecture Method
Assessment Methods:
A: Traditional Written Exam, F: Project Task
Course Outline
Order
Subjects
Preliminary Work
1
Introductory Lecture
2
Introduction to Tissue Engineering
3
How Genetic Engineering serves to Tissue Engineering
4
Stem Cell Tissue Engineering
5
Polymeric Scaffolds for Tissue Engineering Applications
6
Fabrication Methods of Tissue Engineering Scaffolds
7
3D Organ Printing and Cell Encapsulation
8
Basics in Immunology and Immune Host Response to Biomaterials
9
Extracellular Matrix: Structure Function, and Application to Tissue Engineering
10
Microvascular Imaging Methods for Tissue Engineering
11
In Vitro & In Vivo Testing
12
Standards and Regulations in Tissue Engineering Applications: ISO, FDA etc.
13
Project Presentations
14
Selected Topics on Tissue Engineering
Resources
(1) Migliaresi, Claudio, and Antonella Motta. Scaffolds for tissue engineering: Biological design, materials, and fabrication. Jenny Stanford Publishing, 2014.
(2) Birla, Ravi. Introduction to tissue engineering: applications and challenges. John Wiley & Sons, 2014.
(3) Bronzino, Joseph D., and Donald R. Peterson. Tissue engineering and artificial organs. CRC press, 2016
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
X
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
X
10
A knowledge of contemporary issues
X
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
X
12
Capability to apply and decide on engineering principals while understanding and rehabilitating the human body
X
Assessment Methods
Contribution Level
Absolute Evaluation
Rate of Midterm Exam to Success
30
Rate of Final Exam to Success
70
Total
100
ECTS / Workload Table
Activities
Number of
Duration(Hour)
Total Workload(Hour)
Course Hours
14
3
42
Guided Problem Solving
0
0
0
Resolution of Homework Problems and Submission as a Report
3
20
60
Term Project
0
0
0
Presentation of Project / Seminar
0
0
0
Quiz
0
0
0
Midterm Exam
1
30
30
General Exam
1
40
40
Performance Task, Maintenance Plan
0
0
0
Total Workload(Hour)
172
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(172/30)
6
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.
Detail Informations of the Course
Course Description
Course
Code
Semester
T+P (Hour)
Credit
ECTS
TISSUE and GENETIC ENGINEERING
-
Spring Semester
3+0
3
6
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of Course
English
Course Level
First Cycle (Bachelor's Degree)
Course Type
Elective
Course Coordinator
Assoc.Prof. Özge ŞENSOY
Name of Lecturer(s)
Assist.Prof. Mehmet Hikmet ÜÇIŞIK, Assoc.Prof. Özge ŞENSOY
Assistant(s)
Tissue and Genetic Engineering
Aim
Doku mühendisliği, vücuttaki hastalıklı veya yaralı doku ve organları yenilemeyi veya onarmayı amaçlayan bir alandır. Doku mühendisliği, biyoloji, kimya, malzeme bilimi, mühendislik, immünoloji ve transplantasyon gibi birçok farklı bilimi kapsar. Ders, doku büyümesi ve gelişimi ile doku ve organların tasarlanması için gerekli araç ve teorik bilgilerin genel bir anlayışını sağlar. Öğrencilere yönelik öğrenme yöntemi ve sömestir projesi, öğrencilere doku kavramlarını, ilkelerini ve uygulamalarını tanıtmak için öğretim aracı olarak kullanılacaktır.
Course Content
This course contains; Introductory Lecture,Introduction to Tissue Engineering ,How Genetic Engineering serves to Tissue Engineering ,Stem Cell Tissue Engineering ,Polymeric Scaffolds for Tissue Engineering Applications ,Fabrication Methods of Tissue Engineering Scaffolds,3D Organ Printing and Cell Encapsulation,Basics in Immunology and Immune Host Response to Biomaterials,Extracellular Matrix: Structure Function, and Application to Tissue Engineering,Microvascular Imaging Methods for Tissue Engineering,In Vitro & In Vivo Testing,Standards and Regulations in Tissue Engineering Applications: ISO, FDA etc.,Project Presentations,Selected Topics on Tissue Engineering.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
Describe the tissue engineering as a prominent approach composed of different disciplines
10, 13, 14, 37, 5, 9
A, F
Define the different strategies and approaches in tissue engineering
10, 14, 2, 5
A, F
Analyze, evaluate, describe and compare different experimental techniques in tissue engineering
10, 14, 5
A, F
Understand the experimental design of a tissue engineering study
10, 37, 4, 5
A, F
Get the ability to combine their personal knowledge in biology, material science, engineering and medicine to understand and address the challenges in tissue engineering
10, 18, 2, 5
A, F
Describe the national and universal standards for tissue engineering preclinic and clinic applications
10, 18, 2, 5
A, F
Teaching Methods:
10: Discussion Method, 13: Case Study Method, 14: Self Study Method, 18: Micro Teaching Technique, 2: Project Based Learning Model, 37: Computer-Internet Supported Instruction, 4: Inquiry-Based Learning, 5: Cooperative Learning, 9: Lecture Method
Assessment Methods:
A: Traditional Written Exam, F: Project Task
Course Outline
Order
Subjects
Preliminary Work
1
Introductory Lecture
2
Introduction to Tissue Engineering
3
How Genetic Engineering serves to Tissue Engineering
4
Stem Cell Tissue Engineering
5
Polymeric Scaffolds for Tissue Engineering Applications
6
Fabrication Methods of Tissue Engineering Scaffolds
7
3D Organ Printing and Cell Encapsulation
8
Basics in Immunology and Immune Host Response to Biomaterials
9
Extracellular Matrix: Structure Function, and Application to Tissue Engineering
10
Microvascular Imaging Methods for Tissue Engineering
11
In Vitro & In Vivo Testing
12
Standards and Regulations in Tissue Engineering Applications: ISO, FDA etc.
13
Project Presentations
14
Selected Topics on Tissue Engineering
Resources
(1) Migliaresi, Claudio, and Antonella Motta. Scaffolds for tissue engineering: Biological design, materials, and fabrication. Jenny Stanford Publishing, 2014.
(2) Birla, Ravi. Introduction to tissue engineering: applications and challenges. John Wiley & Sons, 2014.
(3) Bronzino, Joseph D., and Donald R. Peterson. Tissue engineering and artificial organs. CRC press, 2016
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
X
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
X
10
A knowledge of contemporary issues
X
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
X
12
Capability to apply and decide on engineering principals while understanding and rehabilitating the human body
