Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ADVANCED BIOCHEMISTRY | - | Fall Semester | 3+0 | 3 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Assoc.Prof. Sultan Sibel ERDEM |
| Name of Lecturer(s) | Assoc.Prof. Sultan Sibel ERDEM |
| Assistant(s) | |
| Aim | |
| Course Content | This course contains; ,Fundamentals of Life,Overview of Metobolism and Life,Carbohydrates and Glycogen Metabolism,Glycolysis,Citric Acid Cycle,Oxidative Phosphorylation,Dietary Lipid Metabolism,Fatty Acid Synthesis,Amino Acids,Enzymes,Proteins,Fibrous Proteinler,Globular Proteins. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Evaluates the structure of macro and micromolecules in the organism. 1.1. Understands the structure of carbohydrates and explains their digestion and absorption. 1.2. Explains the three-dimensional structure of proteins and their digestion and absorption. 1.3. The structure of lipids defines the factors in their digestion and absorption. 1.4. Describes the causes of disorders in the digestive system and understands their mechanisms. 2. Evaluates how blood sugar can stay within certain limits. 2.1. Explains the absorption of glucose and the factors affecting absorption. 2.2.Evaluates the significance of the renal threshold for blood sugar. 2.3.Explains how dietary sugars affect blood sugar. 2.4.Explains how hormones regulate blood sugar. 2.5.Explains the interrelationship of various metabolic pathways related to blood sugar. 3. Describes the lipoproteins related to lipid metabolism. 3.1. Explains the relation between lipoprtoteins and atherosclerosis 4. Describes the structure and functions of proteins. 4.1. Describes globular proteins. 4.2. Describes fibrous proteins. 5. Questions the importance of biological oxidation for energy metabolism. 5.1. Summarizes the hydrogens obtained from foods via the metabolic pathway. 5.2. Explain the reactions that occur in oxidative phosphorylation. 5.3. Explains theories about oxidative phosphorylation. 5.4. Describe the importance of oxidative phosphorylation for life. 6. Compares the effects of vitamins and minerals on metabolism. 6.1. Describes the structure and functions of vitamins. 6.2. Explains the importance of vitamins in metabolism. 6.3. Summarizes macros and minerals. 6.4. Describes the place of macro and microminerals in metabolism and their importance for the cell. 7. Analyzes the structure and functions of enzymes. 7.1. Understands the molecular structure and mechanism of action of enzymes. 7.2. Describes the enzyme kinetics. 7.3. Describes the relationship between enzyme kinetics and reactions. 7.4. Explains the factors affecting enzyme reactions. 8. Analyzes the working conditions of the clinical biochemistry laboratory. 8.1. Explains the rules of working in the laboratory. 8.2. Compares individual safety rules. 8.3. Defines the points to be considered when working with chemicals. 8.4. Compares carcinogenic substances and special extra hazardous substances. 8.5.Explains ways to protect against fire and other harmful substances. 9. Can compare the materials used in the clinical biochemistry laboratory. 9.1 Defines the cleaning materials used in the laboratory. 9.2. Discusses preanalytical, analytical and postanalytical errors. 9.3. Can compare the instruments used in the biochemistry laboratory. 9.4. Can use precision scales and desiccators. 9.5. Can perform measurements of carbohydrates in the laboratory. 10. Makes measurements of lipids in the laboratory. 11. Can perform protein measurement and define electrophoresis. 12. Discusses the measurement principles of enzymes. 13. Defines filter papers and pH paper used in the laboratory. 14. Defines isotonic and osmolar solutions. 15. Defines buffer solutions. 16. Discusses pH measurement and its importance. 17. Applies spectrophotometric, colorimetric and photometric measurements. 18. Explains the principle of the autoanalyzer used in clinical chemistry. 19. Can compare measurements of macromolecules in clinical biochemistry. |
| Teaching Methods: | |
| Assessment Methods: |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 0 | ||
| 1 | Fundamentals of Life | |
| 2 | Overview of Metobolism and Life | |
| 3 | Carbohydrates and Glycogen Metabolism | |
| 4 | Glycolysis | |
| 5 | Citric Acid Cycle | |
| 6 | Oxidative Phosphorylation | |
| 7 | Dietary Lipid Metabolism | |
| 8 | Fatty Acid Synthesis | |
| 9 | Amino Acids | |
| 10 | Enzymes | |
| 11 | Proteins | |
| 12 | Fibrous Proteinler | |
| 12 | Globular Proteins |
| Resources |
| 1) Temel ve Uygulamalı Biyokimya Prof. Dr. Nesrin Emekli Academi Kitapevi Yayınları 2) Öğrenciler için Biyokimya Laboratuarı Doç. Dr. Türkan Yiğitbaşı ve Prof.Dr.Nesrin Emekli 3) Klinik Biyokimya Prof. Dr. Nesrin Emekli ve Doç. Dr. Türkan Yiğitbaşı Medipol Üniversitesi Yayınları 4) Harper’s Illustrated Biochemistry 5) Kolay Biyokimya (Batırel ve ark.) 6) Lippincott’s Illustrated Reviews Biochemistry |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | They develop a skill to access scientific information extensively by doing research on Molecular Medicine and Biotechnology and other related fields and to be able to evaluate, interpret and implement the obtained information | X | |||||
| 2 | They develop a skill to integrate and interpret information on various disciplines concerning practical fields of Molecular Medicine and Biotechnology. | X | |||||
| 3 | They are able to recognize the problems related to Molecular Medicine and Biotechnology field, develop methods for solving those problems, and they can implement the obtained information. | X | |||||
| 4 | They know the fundamental biostatistics approaches and methods. They are able to interpret scientific experimental data statistically. | ||||||
| 5 | They develop a skill to be aware of new and developing applications in the fields of Molecular Medicine and Biotechnology and use and teach them efficiently when necessary. | X | |||||
| 6 | They are able to access available scientific information on the literature related to Molecular Medicine and Biotechnology fields, interpret critically and use such information. | X | |||||
| 7 | They develop a skill to produce new and original ideas and methods. | X | |||||
| 8 | They use their theoretical knowledge and critical thinking ability in their field of study, evaluate and interpret the results, and writes the report of the study. | X | |||||
| 9 | They develop a skill to take the lead within teams doing healthcare studies, develop new ideas to solve complicated situations, and take responsibility. | ||||||
| 10 | They develop a skill to convey (whether in written form or orally) the scientific information obtained by them at national or international platforms in a systematic and open manner. | ||||||
| 11 | They define a scientific or technical problem with the help of a consultant or individually, make suggestions for its solution and solve it when necessary. | X | |||||
| 12 | They develop the ability to act in accordance with ethical and professional principles at all stages of educational, practice, and research activities. They can evaluate the results obtained based on the quality criteria. | X | |||||
| 13 | They can supervise and teach the social, scientific, cultural, and ethical values in the stages of collecting, interpreting, applying, and announcing the data related to the field of Molecular Medicine and Biotechnology. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 5 | 70 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 3 | 30 | 90 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 2 | 4 | 8 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 30 | 30 | |||
| General Exam | 1 | 30 | 30 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 228 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(228/30) | 8 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ADVANCED BIOCHEMISTRY | - | Fall Semester | 3+0 | 3 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Assoc.Prof. Sultan Sibel ERDEM |
| Name of Lecturer(s) | Assoc.Prof. Sultan Sibel ERDEM |
| Assistant(s) | |
| Aim | |
| Course Content | This course contains; ,Fundamentals of Life,Overview of Metobolism and Life,Carbohydrates and Glycogen Metabolism,Glycolysis,Citric Acid Cycle,Oxidative Phosphorylation,Dietary Lipid Metabolism,Fatty Acid Synthesis,Amino Acids,Enzymes,Proteins,Fibrous Proteinler,Globular Proteins. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Evaluates the structure of macro and micromolecules in the organism. 1.1. Understands the structure of carbohydrates and explains their digestion and absorption. 1.2. Explains the three-dimensional structure of proteins and their digestion and absorption. 1.3. The structure of lipids defines the factors in their digestion and absorption. 1.4. Describes the causes of disorders in the digestive system and understands their mechanisms. 2. Evaluates how blood sugar can stay within certain limits. 2.1. Explains the absorption of glucose and the factors affecting absorption. 2.2.Evaluates the significance of the renal threshold for blood sugar. 2.3.Explains how dietary sugars affect blood sugar. 2.4.Explains how hormones regulate blood sugar. 2.5.Explains the interrelationship of various metabolic pathways related to blood sugar. 3. Describes the lipoproteins related to lipid metabolism. 3.1. Explains the relation between lipoprtoteins and atherosclerosis 4. Describes the structure and functions of proteins. 4.1. Describes globular proteins. 4.2. Describes fibrous proteins. 5. Questions the importance of biological oxidation for energy metabolism. 5.1. Summarizes the hydrogens obtained from foods via the metabolic pathway. 5.2. Explain the reactions that occur in oxidative phosphorylation. 5.3. Explains theories about oxidative phosphorylation. 5.4. Describe the importance of oxidative phosphorylation for life. 6. Compares the effects of vitamins and minerals on metabolism. 6.1. Describes the structure and functions of vitamins. 6.2. Explains the importance of vitamins in metabolism. 6.3. Summarizes macros and minerals. 6.4. Describes the place of macro and microminerals in metabolism and their importance for the cell. 7. Analyzes the structure and functions of enzymes. 7.1. Understands the molecular structure and mechanism of action of enzymes. 7.2. Describes the enzyme kinetics. 7.3. Describes the relationship between enzyme kinetics and reactions. 7.4. Explains the factors affecting enzyme reactions. 8. Analyzes the working conditions of the clinical biochemistry laboratory. 8.1. Explains the rules of working in the laboratory. 8.2. Compares individual safety rules. 8.3. Defines the points to be considered when working with chemicals. 8.4. Compares carcinogenic substances and special extra hazardous substances. 8.5.Explains ways to protect against fire and other harmful substances. 9. Can compare the materials used in the clinical biochemistry laboratory. 9.1 Defines the cleaning materials used in the laboratory. 9.2. Discusses preanalytical, analytical and postanalytical errors. 9.3. Can compare the instruments used in the biochemistry laboratory. 9.4. Can use precision scales and desiccators. 9.5. Can perform measurements of carbohydrates in the laboratory. 10. Makes measurements of lipids in the laboratory. 11. Can perform protein measurement and define electrophoresis. 12. Discusses the measurement principles of enzymes. 13. Defines filter papers and pH paper used in the laboratory. 14. Defines isotonic and osmolar solutions. 15. Defines buffer solutions. 16. Discusses pH measurement and its importance. 17. Applies spectrophotometric, colorimetric and photometric measurements. 18. Explains the principle of the autoanalyzer used in clinical chemistry. 19. Can compare measurements of macromolecules in clinical biochemistry. |
| Teaching Methods: | |
| Assessment Methods: |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 0 | ||
| 1 | Fundamentals of Life | |
| 2 | Overview of Metobolism and Life | |
| 3 | Carbohydrates and Glycogen Metabolism | |
| 4 | Glycolysis | |
| 5 | Citric Acid Cycle | |
| 6 | Oxidative Phosphorylation | |
| 7 | Dietary Lipid Metabolism | |
| 8 | Fatty Acid Synthesis | |
| 9 | Amino Acids | |
| 10 | Enzymes | |
| 11 | Proteins | |
| 12 | Fibrous Proteinler | |
| 12 | Globular Proteins |
| Resources |
| 1) Temel ve Uygulamalı Biyokimya Prof. Dr. Nesrin Emekli Academi Kitapevi Yayınları 2) Öğrenciler için Biyokimya Laboratuarı Doç. Dr. Türkan Yiğitbaşı ve Prof.Dr.Nesrin Emekli 3) Klinik Biyokimya Prof. Dr. Nesrin Emekli ve Doç. Dr. Türkan Yiğitbaşı Medipol Üniversitesi Yayınları 4) Harper’s Illustrated Biochemistry 5) Kolay Biyokimya (Batırel ve ark.) 6) Lippincott’s Illustrated Reviews Biochemistry |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | They develop a skill to access scientific information extensively by doing research on Molecular Medicine and Biotechnology and other related fields and to be able to evaluate, interpret and implement the obtained information | X | |||||
| 2 | They develop a skill to integrate and interpret information on various disciplines concerning practical fields of Molecular Medicine and Biotechnology. | X | |||||
| 3 | They are able to recognize the problems related to Molecular Medicine and Biotechnology field, develop methods for solving those problems, and they can implement the obtained information. | X | |||||
| 4 | They know the fundamental biostatistics approaches and methods. They are able to interpret scientific experimental data statistically. | ||||||
| 5 | They develop a skill to be aware of new and developing applications in the fields of Molecular Medicine and Biotechnology and use and teach them efficiently when necessary. | X | |||||
| 6 | They are able to access available scientific information on the literature related to Molecular Medicine and Biotechnology fields, interpret critically and use such information. | X | |||||
| 7 | They develop a skill to produce new and original ideas and methods. | X | |||||
| 8 | They use their theoretical knowledge and critical thinking ability in their field of study, evaluate and interpret the results, and writes the report of the study. | X | |||||
| 9 | They develop a skill to take the lead within teams doing healthcare studies, develop new ideas to solve complicated situations, and take responsibility. | ||||||
| 10 | They develop a skill to convey (whether in written form or orally) the scientific information obtained by them at national or international platforms in a systematic and open manner. | ||||||
| 11 | They define a scientific or technical problem with the help of a consultant or individually, make suggestions for its solution and solve it when necessary. | X | |||||
| 12 | They develop the ability to act in accordance with ethical and professional principles at all stages of educational, practice, and research activities. They can evaluate the results obtained based on the quality criteria. | X | |||||
| 13 | They can supervise and teach the social, scientific, cultural, and ethical values in the stages of collecting, interpreting, applying, and announcing the data related to the field of Molecular Medicine and Biotechnology. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |