Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| BIOCHEMISTRY | - | Yearly | 76+8 | - | 6 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Neslin EMEKLİ |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assist.Prof. Çağrı ÇAKICI, Assist.Prof. Derya CANSIZ |
| Assistant(s) | |
| Aim | |
| Course Content | This course contains; Moleculer fundamental of life ,Carbohydrate metabolism,Energy storage:Glycogen synthesis and catabolism,Glucuronic acid pathway,Energy production I : Glycolysis,Energy production II: Citric acid cycle,Pendose phosphate pathway,Glukoneojenez,Metabolic control of glucose,Spectrophotometer,Blood glucose assay,Lipids ,Triglycerides, phospholipids and eicosanoids,Cholesterol, Steroids and Isoprenes,Lipoproteins,Fatty acid synthesis,Beta oxidation,Oxidative phosphorylation,Lipid analysis,Membrane and Transport,Biologic oxidation and antioxidants,Amino acids and transport,Biosynthesis and catabolism of amino acids,Aminoacid Introducing Reactions,Urea synthesis,Biologic amines,Enyzmes I,Enzymes II,Structure of vitamins,Mechanism action of vitamins,Inorganic molecules I,Inorganic molecules II,Signal Transmission,Structure of hormones,Hormone action metabolism,Structure and function of proteins,Clasifications of proteins,Hemoglobin and Collagen,Protein analysis in blood,Nucleic acids,Buffer systems,Body fluids,Water metabolism. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1.1.Explains the general properties of monosaccharides, disaccharides and polysaccharides. | 16, 17, 19, 9 | A, D, E, G |
| 2.1.Explains diseases caused by enzyme deficiencies in metabolic pathways. | 16, 17, 19, 9 | A, D, E, G |
| 2.2.Explains enzyme deficiencies in urine synthesis. | 16, 17, 19, 9 | A, D, E, G |
| 2.3.Define the diseases of lipid and glycogen storage. | 16, 17, 19, 9 | A, D, E, G |
| 2.4.Explains metabolic control of glucose and metabolic disorders associated with glucose metabolism disorders and atherosclerosis. | 16, 17, 19, 9 | A, D, E, G |
| 3.1.Explains the subjects of biogas, glycogen production and degradation, glycolysis, glycooneogenesis, citric acid cycle, pentose phosphate pathway, oxidative phosphorylation. | 16, 17, 19, 9 | A, D, E, G |
| 3.3.Explains the points of intersection between all metabolic pathways and discusses energy metabolism. | 16, 17, 19, 9 | A, D, E, G |
| 3.4.Explains the metabolic control mechanisms of macromolecules, the effects and relationships of enzymes and hormones in these control steps. Explains signal transmission systems. | 16, 17, 19, 9 | A, D, E, G |
| 3.5.Explains the relationship between energy metabolism and nutrition | 16, 17, 19, 9 | A, D, E, G |
| 1. Explain structure and functions of vitamins and carbohydrates, proteins, lipids, nucleic acids. | 16, 17, 19, 9 | A, D, E, G |
| 1.2. Explains structure and general properties of lipids, fatty acids, lipoproteins, sphingolipids, steroids. | 16, 17, 19, 9 | A, D, E, G |
| 1.3. Explains amino acids and their properties, the structure of proteins, the classification of proteins. | 16, 17, 19, 9 | A, D, E, G |
| 1.4 Defines hormones and their structure and mechanism of action of hormones. | 16, 17, 19, 9 | A, D, E, G |
| 1.5. Explains the general properties of minerals and minerals. | 16, 17, 19, 9 | A, D, E, G |
| 2. Explain the structural and functional importance of macromolecules in human body and discuss their relations with diseases. | 16, 17, 19, 9 | A, D, E, G |
| 3. Explain the anabolic and catabolic pathways and the control steps in these pathways. | 16, 17, 19, 9 | A, D, E, G |
| 3.2. Explains oxidation of fatty acids, ketogenesis lipogenesis, such as fat metabolism related issues. | 16, 17, 19, 9 | A, D, E, G |
| Teaching Methods: | 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Moleculer fundamental of life | In MEBIS, the student was informed about the subject. |
| 2 | Carbohydrate metabolism | In MEBIS, the student was informed about the subject. |
| 3 | Energy storage:Glycogen synthesis and catabolism | In MEBIS, the student was informed about the subject. |
| 4 | Glucuronic acid pathway | In MEBIS, the student was informed about the subject. |
| 5 | Energy production I : Glycolysis | In MEBIS, the student was informed about the subject. |
| 6 | Energy production II: Citric acid cycle | In MEBIS, the student was informed about the subject. |
| 7 | Pendose phosphate pathway | In MEBIS, the student was informed about the subject. |
| 8 | Glukoneojenez | In MEBIS, the student was informed about the subject. |
| 9 | Metabolic control of glucose | In MEBIS, the student was informed about the subject. |
| 10 | Spectrophotometer | In MEBIS, the student was informed about the subject. |
| 11 | Blood glucose assay | In MEBIS, the student was informed about the subject. |
| 12 | Lipids | In MEBIS, the student was informed about the subject. |
| 13 | Triglycerides, phospholipids and eicosanoids | In MEBIS, the student was informed about the subject. |
| 14 | Cholesterol, Steroids and Isoprenes | In MEBIS, the student was informed about the subject. |
| 15 | Lipoproteins | In MEBIS, the student was informed about the subject. |
| 16 | Fatty acid synthesis | In MEBIS, the student was informed about the subject |
| 17 | Beta oxidation | In MEBIS, the student was informed about the subject |
| 18 | Oxidative phosphorylation | In MEBIS, the student was informed about the subject. |
| 19 | Lipid analysis | In MEBIS, the student was informed about the subject. |
| 20 | Membrane and Transport | In MEBIS, the student was informed about the subject. |
| 21 | Biologic oxidation and antioxidants | In MEBIS, the student was informed about the subject. |
| 22 | Amino acids and transport | In MEBIS, the student was informed about the subject. |
| 23 | Biosynthesis and catabolism of amino acids | In MEBIS, the student was informed about the subject. |
| 24 | Aminoacid Introducing Reactions | In MEBIS, the student was informed about the subject. |
| 25 | Urea synthesis | In MEBIS, the student was informed about the subject. |
| 26 | Biologic amines | In MEBIS, the student was informed about the subject. |
| 27 | Enyzmes I | In MEBIS, the student was informed about the subject. |
| 28 | Enzymes II | In MEBIS, the student was informed about the subject. |
| 29 | Structure of vitamins | In MEBIS, the student was informed about the subject. |
| 30 | Mechanism action of vitamins | In MEBIS, the student was informed about the subject. |
| 31 | Inorganic molecules I | In MEBIS, the student was informed about the subject. |
| 32 | Inorganic molecules II | In MEBIS, the student was informed about the subject. |
| 33 | Signal Transmission | In MEBIS, the student was informed about the subject. |
| 34 | Structure of hormones | In MEBIS, the student was informed about the subject. |
| 35 | Hormone action metabolism | In MEBIS, the student was informed about the subject. |
| 36 | Structure and function of proteins | In MEBIS, the student was informed about the subject. |
| 37 | Clasifications of proteins | In MEBIS, the student was informed about the subject. |
| 38 | Hemoglobin and Collagen | In MEBIS, the student was informed about the subject. |
| 39 | Protein analysis in blood | In MEBIS, the student was informed about the subject. |
| 40 | Nucleic acids | In MEBIS, the student was informed about the subject. |
| 41 | Buffer systems | In MEBIS, the student was informed about the subject. |
| 42 | Body fluids | In MEBIS, the student was informed about the subject. |
| 43 | Water metabolism | In MEBIS, the student was informed about the subject. |
| Resources |
| 1.Basic and Applied Biochemistry (Nesrin Emekli ), 2.Biochemistry (Fügen Gürdöl ve Evin Ademoğlu), 3.Biochemistry Laboratory(Türkan Yiğitbaşı,Nesrin Emekli). |
| 4.Harper's Biochemistry, 5.Lehninger Principles of Biochemistry, 6.Henry's Clinical Diagnosis and Management by Laboratory Methods. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 0 | 0 | 0 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 0 | 0 | 0 | |||
| General Exam | 0 | 0 | 0 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 0 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(0/30) | 0 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| BIOCHEMISTRY | - | Yearly | 76+8 | - | 6 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Neslin EMEKLİ |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assist.Prof. Çağrı ÇAKICI, Assist.Prof. Derya CANSIZ |
| Assistant(s) | |
| Aim | |
| Course Content | This course contains; Moleculer fundamental of life ,Carbohydrate metabolism,Energy storage:Glycogen synthesis and catabolism,Glucuronic acid pathway,Energy production I : Glycolysis,Energy production II: Citric acid cycle,Pendose phosphate pathway,Glukoneojenez,Metabolic control of glucose,Spectrophotometer,Blood glucose assay,Lipids ,Triglycerides, phospholipids and eicosanoids,Cholesterol, Steroids and Isoprenes,Lipoproteins,Fatty acid synthesis,Beta oxidation,Oxidative phosphorylation,Lipid analysis,Membrane and Transport,Biologic oxidation and antioxidants,Amino acids and transport,Biosynthesis and catabolism of amino acids,Aminoacid Introducing Reactions,Urea synthesis,Biologic amines,Enyzmes I,Enzymes II,Structure of vitamins,Mechanism action of vitamins,Inorganic molecules I,Inorganic molecules II,Signal Transmission,Structure of hormones,Hormone action metabolism,Structure and function of proteins,Clasifications of proteins,Hemoglobin and Collagen,Protein analysis in blood,Nucleic acids,Buffer systems,Body fluids,Water metabolism. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1.1.Explains the general properties of monosaccharides, disaccharides and polysaccharides. | 16, 17, 19, 9 | A, D, E, G |
| 2.1.Explains diseases caused by enzyme deficiencies in metabolic pathways. | 16, 17, 19, 9 | A, D, E, G |
| 2.2.Explains enzyme deficiencies in urine synthesis. | 16, 17, 19, 9 | A, D, E, G |
| 2.3.Define the diseases of lipid and glycogen storage. | 16, 17, 19, 9 | A, D, E, G |
| 2.4.Explains metabolic control of glucose and metabolic disorders associated with glucose metabolism disorders and atherosclerosis. | 16, 17, 19, 9 | A, D, E, G |
| 3.1.Explains the subjects of biogas, glycogen production and degradation, glycolysis, glycooneogenesis, citric acid cycle, pentose phosphate pathway, oxidative phosphorylation. | 16, 17, 19, 9 | A, D, E, G |
| 3.3.Explains the points of intersection between all metabolic pathways and discusses energy metabolism. | 16, 17, 19, 9 | A, D, E, G |
| 3.4.Explains the metabolic control mechanisms of macromolecules, the effects and relationships of enzymes and hormones in these control steps. Explains signal transmission systems. | 16, 17, 19, 9 | A, D, E, G |
| 3.5.Explains the relationship between energy metabolism and nutrition | 16, 17, 19, 9 | A, D, E, G |
| 1. Explain structure and functions of vitamins and carbohydrates, proteins, lipids, nucleic acids. | 16, 17, 19, 9 | A, D, E, G |
| 1.2. Explains structure and general properties of lipids, fatty acids, lipoproteins, sphingolipids, steroids. | 16, 17, 19, 9 | A, D, E, G |
| 1.3. Explains amino acids and their properties, the structure of proteins, the classification of proteins. | 16, 17, 19, 9 | A, D, E, G |
| 1.4 Defines hormones and their structure and mechanism of action of hormones. | 16, 17, 19, 9 | A, D, E, G |
| 1.5. Explains the general properties of minerals and minerals. | 16, 17, 19, 9 | A, D, E, G |
| 2. Explain the structural and functional importance of macromolecules in human body and discuss their relations with diseases. | 16, 17, 19, 9 | A, D, E, G |
| 3. Explain the anabolic and catabolic pathways and the control steps in these pathways. | 16, 17, 19, 9 | A, D, E, G |
| 3.2. Explains oxidation of fatty acids, ketogenesis lipogenesis, such as fat metabolism related issues. | 16, 17, 19, 9 | A, D, E, G |
| Teaching Methods: | 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Moleculer fundamental of life | In MEBIS, the student was informed about the subject. |
| 2 | Carbohydrate metabolism | In MEBIS, the student was informed about the subject. |
| 3 | Energy storage:Glycogen synthesis and catabolism | In MEBIS, the student was informed about the subject. |
| 4 | Glucuronic acid pathway | In MEBIS, the student was informed about the subject. |
| 5 | Energy production I : Glycolysis | In MEBIS, the student was informed about the subject. |
| 6 | Energy production II: Citric acid cycle | In MEBIS, the student was informed about the subject. |
| 7 | Pendose phosphate pathway | In MEBIS, the student was informed about the subject. |
| 8 | Glukoneojenez | In MEBIS, the student was informed about the subject. |
| 9 | Metabolic control of glucose | In MEBIS, the student was informed about the subject. |
| 10 | Spectrophotometer | In MEBIS, the student was informed about the subject. |
| 11 | Blood glucose assay | In MEBIS, the student was informed about the subject. |
| 12 | Lipids | In MEBIS, the student was informed about the subject. |
| 13 | Triglycerides, phospholipids and eicosanoids | In MEBIS, the student was informed about the subject. |
| 14 | Cholesterol, Steroids and Isoprenes | In MEBIS, the student was informed about the subject. |
| 15 | Lipoproteins | In MEBIS, the student was informed about the subject. |
| 16 | Fatty acid synthesis | In MEBIS, the student was informed about the subject |
| 17 | Beta oxidation | In MEBIS, the student was informed about the subject |
| 18 | Oxidative phosphorylation | In MEBIS, the student was informed about the subject. |
| 19 | Lipid analysis | In MEBIS, the student was informed about the subject. |
| 20 | Membrane and Transport | In MEBIS, the student was informed about the subject. |
| 21 | Biologic oxidation and antioxidants | In MEBIS, the student was informed about the subject. |
| 22 | Amino acids and transport | In MEBIS, the student was informed about the subject. |
| 23 | Biosynthesis and catabolism of amino acids | In MEBIS, the student was informed about the subject. |
| 24 | Aminoacid Introducing Reactions | In MEBIS, the student was informed about the subject. |
| 25 | Urea synthesis | In MEBIS, the student was informed about the subject. |
| 26 | Biologic amines | In MEBIS, the student was informed about the subject. |
| 27 | Enyzmes I | In MEBIS, the student was informed about the subject. |
| 28 | Enzymes II | In MEBIS, the student was informed about the subject. |
| 29 | Structure of vitamins | In MEBIS, the student was informed about the subject. |
| 30 | Mechanism action of vitamins | In MEBIS, the student was informed about the subject. |
| 31 | Inorganic molecules I | In MEBIS, the student was informed about the subject. |
| 32 | Inorganic molecules II | In MEBIS, the student was informed about the subject. |
| 33 | Signal Transmission | In MEBIS, the student was informed about the subject. |
| 34 | Structure of hormones | In MEBIS, the student was informed about the subject. |
| 35 | Hormone action metabolism | In MEBIS, the student was informed about the subject. |
| 36 | Structure and function of proteins | In MEBIS, the student was informed about the subject. |
| 37 | Clasifications of proteins | In MEBIS, the student was informed about the subject. |
| 38 | Hemoglobin and Collagen | In MEBIS, the student was informed about the subject. |
| 39 | Protein analysis in blood | In MEBIS, the student was informed about the subject. |
| 40 | Nucleic acids | In MEBIS, the student was informed about the subject. |
| 41 | Buffer systems | In MEBIS, the student was informed about the subject. |
| 42 | Body fluids | In MEBIS, the student was informed about the subject. |
| 43 | Water metabolism | In MEBIS, the student was informed about the subject. |
| Resources |
| 1.Basic and Applied Biochemistry (Nesrin Emekli ), 2.Biochemistry (Fügen Gürdöl ve Evin Ademoğlu), 3.Biochemistry Laboratory(Türkan Yiğitbaşı,Nesrin Emekli). |
| 4.Harper's Biochemistry, 5.Lehninger Principles of Biochemistry, 6.Henry's Clinical Diagnosis and Management by Laboratory Methods. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |