Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| RESEARCH METHODOLOGY and BIOISTATISTICS | PHA2213097 | Spring Semester | 2+0 | 2 | 3 |
| Course Program | Çarşamba 15:30-16:15 Çarşamba 16:30-17:15 Cumartesi 16:30-17:15 Cumartesi 17:30-18:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Mehmet KOÇAK |
| Name of Lecturer(s) | Prof.Dr. Mehmet KOÇAK |
| Assistant(s) | |
| Aim | To give basic information of biostatistical methodology to solve problems related to pharmaceutical research and analysis and to increase the statistical literacy. |
| Course Content | This course contains; Basic Statistical terminology,Descriptive Statistics, frequency tables,Concept and Measures of central tendency,Concept and Measures of variation,Normal Distribution and applications ,Data analysis with SPSS (assumptions of normality, descriptive statistics),Central Limit theorem and Confidence Interval,Concept of Hypothesis testing,Concept of correlation ,Concept of Regression Modelling,The importance and steps of the scientific research process - Research in Health Sciences ,Research methods: observational research design,Research Techniques - Experimental Researches,General Review of the course. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Will be able to describe the fundamental steps of statistical methodology that are relevant to implement the scientific research | 10, 12, 16, 6, 9 | A |
| 1.1. Recognizes the data collection methods in a comparative manner | 16, 9 | A |
| 1.2. Arranges data | 16, 9 | A |
| 1.3. Summarizes data using graphs and diagrams | 16, 9 | A |
| 2. Applies the techniques of statistical analysis to pharmaceutical problems in particular | 10, 12, 16, 6, 9 | A |
| 2.1. Applies descriptive statistical techniques | 16, 6, 9 | A |
| 2.2. Uses inferential statistical techniques for statistical generalization | 10, 12, 16, 6, 9 | A |
| 2.3. Recognizes the fundamentals of statistical decision theory | 10, 12, 6, 9 | A |
| 2.4. Comprehends and applies the fundamentals of two- dimensional(bivariate) analysis | 10, 12, 16, 6, 9 | A |
| 2.5. Investigates the association between two continuous variables | 10, 12, 16, 6, 9 | A |
| 2.6. Comprehends and applies the concepts of correlation and regression | 10, 12, 16, 6, 9 | A |
| 2.7. Recognizes the essential nonparametric methods | 10, 12, 16, 6, 9 | A |
| 3.1. Solves problems in health and particularly in pharmaceutical sciences by using analytical techniques | 10, 12, 16, 6, 9 | A |
| 3.2. Interprets and reports the results obtained | 10, 12, 16, 6, 9 | A |
| 3.3. Uses a statistical software packages selected for the course for basic statistics | 10, 12, 16, 6, 9 | A |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 16: Question - Answer Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Basic Statistical terminology | Sümbuloglu,.1-6 |
| 2 | Descriptive Statistics, frequency tables | Sümbuloglu, 7-23 |
| 3 | Concept and Measures of central tendency | Sumbuloglu, 11-23 |
| 4 | Concept and Measures of variation | Sumbuloglu, 23-27 |
| 5 | Normal Distribution and applications | Sümbüloğlu s.44-47 |
| 6 | Data analysis with SPSS (assumptions of normality, descriptive statistics) | Hayran ve Ozbek,.57-82 |
| 9 | Central Limit theorem and Confidence Interval | Rosner |
| 9 | Concept of Hypothesis testing | Sümbüloğlu s. 48-57 |
| 10 | Concept of correlation | Hayran ve Ozbek, s.257-280 |
| 11 | Concept of Regression Modelling | Hayran ve Ozbek, 257-280 |
| 12 | The importance and steps of the scientific research process - Research in Health Sciences | Hayran ve Ozbek, s. 7-15 |
| 13 | Research methods: observational research design | Hayran ve Ozbek, s. 18-22 |
| 14 | Research Techniques - Experimental Researches | Hayran ve Ozbek, 7-15 |
| 15 | General Review of the course | Sumbuloglu, 15-18 |
| Resources |
| Hayran, Osman ve Özbek Hanefi "Sağlık Bilimlerinde Araştırma ve İstatistik Yöntemler (SPSS Uygulama Örnekleri ile Genişletilmiş 2. Baskı)", 2017, Nobel Tıp Kitabevleri. Sümbüloğlu, Kadir, and Vildan Sümbüloğlu. Biyoistatistik. Hatiboğlu, 2002. Field, Andy. Discovering statistics using SPSS. Sage publications, 2009. Rosner, B. (2015). Fundamentals of biostatistics. Wayne W. Daniel, Chad L. Cross Biostatistics: A Foundation for Analysis in the Health Sciences, 11th Ed. Wiley 2018, J. Richard Hebel , Robert J. McCarter Study Guide to Epidemiology and Biostatistics, 7th EditionA.J. Silman,g. J. Macfarlane, Macfarlane, Epidemiological Studies: A Practical Guide Third Edition 3.Ed |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | ||||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | ||||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | ||||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | ||||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 4 | 2 | 8 | |||
| Resolution of Homework Problems and Submission as a Report | 1 | 4 | 4 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 1 | 1 | 1 | |||
| Midterm Exam | 1 | 21 | 21 | |||
| General Exam | 1 | 26 | 26 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 88 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(88/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| RESEARCH METHODOLOGY and BIOISTATISTICS | PHA2213097 | Spring Semester | 2+0 | 2 | 3 |
| Course Program | Çarşamba 15:30-16:15 Çarşamba 16:30-17:15 Cumartesi 16:30-17:15 Cumartesi 17:30-18:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Mehmet KOÇAK |
| Name of Lecturer(s) | Prof.Dr. Mehmet KOÇAK |
| Assistant(s) | |
| Aim | To give basic information of biostatistical methodology to solve problems related to pharmaceutical research and analysis and to increase the statistical literacy. |
| Course Content | This course contains; Basic Statistical terminology,Descriptive Statistics, frequency tables,Concept and Measures of central tendency,Concept and Measures of variation,Normal Distribution and applications ,Data analysis with SPSS (assumptions of normality, descriptive statistics),Central Limit theorem and Confidence Interval,Concept of Hypothesis testing,Concept of correlation ,Concept of Regression Modelling,The importance and steps of the scientific research process - Research in Health Sciences ,Research methods: observational research design,Research Techniques - Experimental Researches,General Review of the course. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Will be able to describe the fundamental steps of statistical methodology that are relevant to implement the scientific research | 10, 12, 16, 6, 9 | A |
| 1.1. Recognizes the data collection methods in a comparative manner | 16, 9 | A |
| 1.2. Arranges data | 16, 9 | A |
| 1.3. Summarizes data using graphs and diagrams | 16, 9 | A |
| 2. Applies the techniques of statistical analysis to pharmaceutical problems in particular | 10, 12, 16, 6, 9 | A |
| 2.1. Applies descriptive statistical techniques | 16, 6, 9 | A |
| 2.2. Uses inferential statistical techniques for statistical generalization | 10, 12, 16, 6, 9 | A |
| 2.3. Recognizes the fundamentals of statistical decision theory | 10, 12, 6, 9 | A |
| 2.4. Comprehends and applies the fundamentals of two- dimensional(bivariate) analysis | 10, 12, 16, 6, 9 | A |
| 2.5. Investigates the association between two continuous variables | 10, 12, 16, 6, 9 | A |
| 2.6. Comprehends and applies the concepts of correlation and regression | 10, 12, 16, 6, 9 | A |
| 2.7. Recognizes the essential nonparametric methods | 10, 12, 16, 6, 9 | A |
| 3.1. Solves problems in health and particularly in pharmaceutical sciences by using analytical techniques | 10, 12, 16, 6, 9 | A |
| 3.2. Interprets and reports the results obtained | 10, 12, 16, 6, 9 | A |
| 3.3. Uses a statistical software packages selected for the course for basic statistics | 10, 12, 16, 6, 9 | A |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 16: Question - Answer Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Basic Statistical terminology | Sümbuloglu,.1-6 |
| 2 | Descriptive Statistics, frequency tables | Sümbuloglu, 7-23 |
| 3 | Concept and Measures of central tendency | Sumbuloglu, 11-23 |
| 4 | Concept and Measures of variation | Sumbuloglu, 23-27 |
| 5 | Normal Distribution and applications | Sümbüloğlu s.44-47 |
| 6 | Data analysis with SPSS (assumptions of normality, descriptive statistics) | Hayran ve Ozbek,.57-82 |
| 9 | Central Limit theorem and Confidence Interval | Rosner |
| 9 | Concept of Hypothesis testing | Sümbüloğlu s. 48-57 |
| 10 | Concept of correlation | Hayran ve Ozbek, s.257-280 |
| 11 | Concept of Regression Modelling | Hayran ve Ozbek, 257-280 |
| 12 | The importance and steps of the scientific research process - Research in Health Sciences | Hayran ve Ozbek, s. 7-15 |
| 13 | Research methods: observational research design | Hayran ve Ozbek, s. 18-22 |
| 14 | Research Techniques - Experimental Researches | Hayran ve Ozbek, 7-15 |
| 15 | General Review of the course | Sumbuloglu, 15-18 |
| Resources |
| Hayran, Osman ve Özbek Hanefi "Sağlık Bilimlerinde Araştırma ve İstatistik Yöntemler (SPSS Uygulama Örnekleri ile Genişletilmiş 2. Baskı)", 2017, Nobel Tıp Kitabevleri. Sümbüloğlu, Kadir, and Vildan Sümbüloğlu. Biyoistatistik. Hatiboğlu, 2002. Field, Andy. Discovering statistics using SPSS. Sage publications, 2009. Rosner, B. (2015). Fundamentals of biostatistics. Wayne W. Daniel, Chad L. Cross Biostatistics: A Foundation for Analysis in the Health Sciences, 11th Ed. Wiley 2018, J. Richard Hebel , Robert J. McCarter Study Guide to Epidemiology and Biostatistics, 7th EditionA.J. Silman,g. J. Macfarlane, Macfarlane, Epidemiological Studies: A Practical Guide Third Edition 3.Ed |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | ||||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | ||||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | ||||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | ||||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |