Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| RESEARCH METHODOLOGY and BIOISTATISTICS | - | Spring Semester | 2+0 | 2 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Abdulbari BENER |
| Name of Lecturer(s) | Assoc.Prof. Pakize YİĞİT |
| Assistant(s) | |
| Aim | To give basic information of biostatistical methodology to solve problems related to pharmaceutical research and analysis. |
| Course Content | This course contains; Statistics in Health and basic therminology,Descriptive Statistics, Series, frequency table, grouped frequency table,Descriptive Statistics (measures of central tendency ),Descriptive Statistics (Measures of variation ),Normal Distribution and applications,Data analysis with SPSS,( assumtions of normality, discriptive statistics),Determination of sample size-two and multivariate graphes,Central Limit theorem and Confidence Interval, Hypothesis test,Bivariate correlation,Regression Analysis,The importance and steps of the scientific research process - Research in Health Sciences, Research methods : observational research design,Research Techniques-Experimental Researches. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 2.2. uses inferential statistical techniques for statistical generalization. | 13, 16, 9 | A |
| 1. will be able to describe the fundamental steps of statistical methodology which are relevant to implement the research process. | 13, 16, 9 | A |
| 1.1. recognizes data collection methods comparatively. | 13, 16, 9 | A |
| 1.2. arranges data. | 13, 16, 9 | A |
| 1.3. summarizes data using graphs and diagrams. | 13, 16, 9 | A |
| 2. will be able to apply the techniques of statistical analysis to pharmaceutical problems in particular. | 13, 16, 9 | A |
| 2.1. applies descriptive statistical techniques. | 13, 16, 9 | A |
| 2.3. recognizes the fundamentals of statistical decision theory. | 13, 16, 9 | A |
| 2.4. comprehends and applies the fundamentals of two- dimensional(bivariate) analysis. | 13, 16, 9 | A |
| 2.5. recognizes the essential nonparametric methods, which are relevant to pharmaceutical research. | 13, 16, 9 | A |
| 3. will be able to improve his/her ability to solve problems and interpret results. | 13, 16, 9 | A |
| 3.1. solves problems in health and particularly in pharmaceutical sciences by using analytical techniques. | 13, 16, 9 | A |
| 3.2. reports the results obtained. | 13, 16, 9 | A |
| 3.3. uses and interacts with statistical softwares for statistical analysis. | 13, 16, 9 | A |
| Teaching Methods: | 13: Case Study Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Statistics in Health and basic therminology | Sumbuloglu, s.1-6 |
| 2 | Descriptive Statistics, Series, frequency table, grouped frequency table | Sumbuloglu, s.7-23 |
| 3 | Descriptive Statistics (measures of central tendency ) | Sümbüloglu, s.11-23 |
| 4 | Descriptive Statistics (Measures of variation ) | Sümbüloğlu 23-27 |
| 5 | Normal Distribution and applications | Sümbüloğlu s.44-47 |
| 6 | Data analysis with SPSS,( assumtions of normality, discriptive statistics) | Hayran ve Ozbek, s.57-82 |
| 7 | Determination of sample size-two and multivariate graphes | Sümbüloğlu s. 264-267 |
| 8 | Central Limit theorem and Confidence Interval | Orhunbilge, 19-41 |
| 9 | Hypothesis test | Sümbüloğlu s. 48,57 |
| 10 | Bivariate correlation | Hayran ve Ozbek, s.257-280 |
| 11 | Regression Analysis | Hayran ve Ozbek, s.257-280 |
| 13 | The importance and steps of the scientific research process - Research in Health Sciences | Hayran ve Özbek, s. 18-22 |
| 14 | Research methods : observational research design | Hayran ve Ozbek, s. 7-15 |
| 15 | Research Techniques-Experimental Researches | Hayran ve Ozbek, s. 15-18 |
| Resources |
| 1. Hayran, Osman ve Özbek Hanefi "Sağlık Bilimlerinde Araştırma ve İstatistik Yöntemler (SPSS Uygulama Örnekleri ile Genişletilmiş 2. Baskı)", 2017, Nobel Tıp Kitabevleri. 2. Sümbüloğlu, Kadir, and Vildan Sümbüloğlu. Biyoistatistik. Hatiboğlu, 2002. 3. Neyran Orhunbilge, «Tanımsal İstatistik Olasılık ve Olasılık Dağılımları», İstanbul Üniversitesi,İşletme Fak. Yay, 2000. 4. Sümbüloğlu, K. (2007). Regresyon yöntemleri ve korelasyon analizi. Hatiboğlu Yayınları. 5. Orhunbilge, N. (2000). Örnekleme yöntemleri ve hipotez testleri. Avcıol Basım Yayın. 6. Field, Andy. Discovering statistics using SPSS. Sage publications, 2009. 7. Rosner, B. (2015). Fundamentals of biostatistics. Nelson Education. 8. Erdoğan, S., Nahcivan, N., & Esin, M. N. (Eds.). (2015). Hemşirelikte araştırma: süreç, ugulama ve kritik. Nobel Tıp Kitabevi |
| Lecture notes, web sites relevant to topics, power points |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | ||||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | ||||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | ||||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | ||||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 4 | 2 | 8 | |||
| Resolution of Homework Problems and Submission as a Report | 1 | 4 | 4 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 1 | 1 | 1 | |||
| Midterm Exam | 1 | 21 | 21 | |||
| General Exam | 1 | 26 | 26 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 88 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(88/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| RESEARCH METHODOLOGY and BIOISTATISTICS | - | Spring Semester | 2+0 | 2 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Abdulbari BENER |
| Name of Lecturer(s) | Assoc.Prof. Pakize YİĞİT |
| Assistant(s) | |
| Aim | To give basic information of biostatistical methodology to solve problems related to pharmaceutical research and analysis. |
| Course Content | This course contains; Statistics in Health and basic therminology,Descriptive Statistics, Series, frequency table, grouped frequency table,Descriptive Statistics (measures of central tendency ),Descriptive Statistics (Measures of variation ),Normal Distribution and applications,Data analysis with SPSS,( assumtions of normality, discriptive statistics),Determination of sample size-two and multivariate graphes,Central Limit theorem and Confidence Interval, Hypothesis test,Bivariate correlation,Regression Analysis,The importance and steps of the scientific research process - Research in Health Sciences, Research methods : observational research design,Research Techniques-Experimental Researches. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 2.2. uses inferential statistical techniques for statistical generalization. | 13, 16, 9 | A |
| 1. will be able to describe the fundamental steps of statistical methodology which are relevant to implement the research process. | 13, 16, 9 | A |
| 1.1. recognizes data collection methods comparatively. | 13, 16, 9 | A |
| 1.2. arranges data. | 13, 16, 9 | A |
| 1.3. summarizes data using graphs and diagrams. | 13, 16, 9 | A |
| 2. will be able to apply the techniques of statistical analysis to pharmaceutical problems in particular. | 13, 16, 9 | A |
| 2.1. applies descriptive statistical techniques. | 13, 16, 9 | A |
| 2.3. recognizes the fundamentals of statistical decision theory. | 13, 16, 9 | A |
| 2.4. comprehends and applies the fundamentals of two- dimensional(bivariate) analysis. | 13, 16, 9 | A |
| 2.5. recognizes the essential nonparametric methods, which are relevant to pharmaceutical research. | 13, 16, 9 | A |
| 3. will be able to improve his/her ability to solve problems and interpret results. | 13, 16, 9 | A |
| 3.1. solves problems in health and particularly in pharmaceutical sciences by using analytical techniques. | 13, 16, 9 | A |
| 3.2. reports the results obtained. | 13, 16, 9 | A |
| 3.3. uses and interacts with statistical softwares for statistical analysis. | 13, 16, 9 | A |
| Teaching Methods: | 13: Case Study Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Statistics in Health and basic therminology | Sumbuloglu, s.1-6 |
| 2 | Descriptive Statistics, Series, frequency table, grouped frequency table | Sumbuloglu, s.7-23 |
| 3 | Descriptive Statistics (measures of central tendency ) | Sümbüloglu, s.11-23 |
| 4 | Descriptive Statistics (Measures of variation ) | Sümbüloğlu 23-27 |
| 5 | Normal Distribution and applications | Sümbüloğlu s.44-47 |
| 6 | Data analysis with SPSS,( assumtions of normality, discriptive statistics) | Hayran ve Ozbek, s.57-82 |
| 7 | Determination of sample size-two and multivariate graphes | Sümbüloğlu s. 264-267 |
| 8 | Central Limit theorem and Confidence Interval | Orhunbilge, 19-41 |
| 9 | Hypothesis test | Sümbüloğlu s. 48,57 |
| 10 | Bivariate correlation | Hayran ve Ozbek, s.257-280 |
| 11 | Regression Analysis | Hayran ve Ozbek, s.257-280 |
| 13 | The importance and steps of the scientific research process - Research in Health Sciences | Hayran ve Özbek, s. 18-22 |
| 14 | Research methods : observational research design | Hayran ve Ozbek, s. 7-15 |
| 15 | Research Techniques-Experimental Researches | Hayran ve Ozbek, s. 15-18 |
| Resources |
| 1. Hayran, Osman ve Özbek Hanefi "Sağlık Bilimlerinde Araştırma ve İstatistik Yöntemler (SPSS Uygulama Örnekleri ile Genişletilmiş 2. Baskı)", 2017, Nobel Tıp Kitabevleri. 2. Sümbüloğlu, Kadir, and Vildan Sümbüloğlu. Biyoistatistik. Hatiboğlu, 2002. 3. Neyran Orhunbilge, «Tanımsal İstatistik Olasılık ve Olasılık Dağılımları», İstanbul Üniversitesi,İşletme Fak. Yay, 2000. 4. Sümbüloğlu, K. (2007). Regresyon yöntemleri ve korelasyon analizi. Hatiboğlu Yayınları. 5. Orhunbilge, N. (2000). Örnekleme yöntemleri ve hipotez testleri. Avcıol Basım Yayın. 6. Field, Andy. Discovering statistics using SPSS. Sage publications, 2009. 7. Rosner, B. (2015). Fundamentals of biostatistics. Nelson Education. 8. Erdoğan, S., Nahcivan, N., & Esin, M. N. (Eds.). (2015). Hemşirelikte araştırma: süreç, ugulama ve kritik. Nobel Tıp Kitabevi |
| Lecture notes, web sites relevant to topics, power points |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | ||||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | ||||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | ||||||
| 14 | PQ-14. Record and document all professional activities and applications. | ||||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | ||||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | ||||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |