Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOGNOSY LAB. I | - | Fall Semester | 0+3 | 1,5 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma TOSUN |
| Name of Lecturer(s) | Assist.Prof. Tuğba İDUĞ, Prof.Dr. Fatma TOSUN |
| Assistant(s) | |
| Aim | To provide identification of botanical drugs with glycosidic and phenolic active substances by microscopic examination, and chemical identification of biologically active phenolic compounds and quantitative determination of glycosides in medicinal plants. |
| Course Content | This course contains; 1. Demostration,2. Microscopic examination of pulverized drugs 1,3. Microscopic examination of pulverized drugs 2,4. Microscopic examination of pulverized drugs 3,5. Microscopic examination of pulverized drugs 4,6. Microscopic examination of pulverized drugs 5,7. Identification of monosaccharides and polysaccharides,8. Identification of anthraquinones,9. Identification of tannins,10. Identification of flavonoids,11. Application of Thin layer chromatography,12. Identification of cyanogenic glycosides,13. Identification of cardiotonic glycosides,14. Quantitative determination of total ashes and determination of foam value. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Proficiently use microscope to identify botanical drugs. | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 1.1. Recognize drugs using characteristic microscopical elements such as druses, plant tissues, glandular trichomes, etc. | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 1.2. Identify the presence of any adulteration in the identified drug material | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 2. Detect the presence of anthraquinones and tannins in plant material and/or botanical drugs using identification reactions | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 2.1. Detect the presence of flavonoids and cyanogenic glycosides in plant material and/or botanical drugs using identification reactions | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 2.2. Detect the presence of cardiotonic glycosides in plant material and/or botanical drugs using various deoxysugar identification reactions | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 3. Perform qualitative and quantitative analyses of biologically active substances in plant materials and/or botanical drugs using chromatographic and other similar techniques | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 3.1. Separate and identify biologically active compounds of botanical drugs using Thin Layer Chromatography (TLC) and special reagents | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 3.2. Perform foam value determination of drugs containing saponins | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 5: Cooperative Learning, 8: Flipped Classroom Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1. Demostration | 1, 2, 3, 4 |
| 2 | 2. Microscopic examination of pulverized drugs 1 | 1, 2, 3, 4 |
| 3 | 3. Microscopic examination of pulverized drugs 2 | 1, 2, 3, 4 |
| 4 | 4. Microscopic examination of pulverized drugs 3 | 1, 2, 3, 4 |
| 5 | 5. Microscopic examination of pulverized drugs 4 | 1, 2, 3, 4 |
| 6 | 6. Microscopic examination of pulverized drugs 5 | 1, 2, 3, 4 |
| 7 | 7. Identification of monosaccharides and polysaccharides | 1, 2, 3, 4 |
| 8 | 8. Identification of anthraquinones | 1, 2, 3, 4 |
| 9 | 9. Identification of tannins | 1, 2, 3, 4 |
| 10 | 10. Identification of flavonoids | 1, 2, 3, 4 |
| 11 | 11. Application of Thin layer chromatography | 1, 2, 3, 4 |
| 12 | 12. Identification of cyanogenic glycosides | 1, 2, 3, 4 |
| 13 | 13. Identification of cardiotonic glycosides | 1, 2, 3, 4 |
| 14 | 14. Quantitative determination of total ashes and determination of foam value | 1, 2, 3, 4 |
| Resources |
| 1- Pharmacognosy 1 Laboratory lecture notes will be provided to students. 2- Upton, R., Graff, A., Jolliffe, G., Williamson, E. (2011) American Herbal Pharmacopoeia Botanical Pharmacognosy - Microscopic Characterization of Botanical Medicines, CRC Press aylor&Francis Group 3- Wagner, H. And Bladt, S. (2009) Plant Drug Analysis: A Thin Layer Chromatgraphy Atlas 2nd Ed. Springer 4- Jackson, B. P., Snowdon, D. W. (2019) eBook Atlas of Microscopy of Medicinal Plants, Culinary Herbs and Spices CBS Publishers & Distributors 5- Heinrich, M. (2012) Fundamentals of Pharmacognosy and Phytotherapy 2Ed. Elsevier Health Sciences |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 1 | 8 | 8 | |||
| Midterm Exam | 1 | 14 | 14 | |||
| General Exam | 1 | 24 | 24 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 88 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(88/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOGNOSY LAB. I | - | Fall Semester | 0+3 | 1,5 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma TOSUN |
| Name of Lecturer(s) | Assist.Prof. Tuğba İDUĞ, Prof.Dr. Fatma TOSUN |
| Assistant(s) | |
| Aim | To provide identification of botanical drugs with glycosidic and phenolic active substances by microscopic examination, and chemical identification of biologically active phenolic compounds and quantitative determination of glycosides in medicinal plants. |
| Course Content | This course contains; 1. Demostration,2. Microscopic examination of pulverized drugs 1,3. Microscopic examination of pulverized drugs 2,4. Microscopic examination of pulverized drugs 3,5. Microscopic examination of pulverized drugs 4,6. Microscopic examination of pulverized drugs 5,7. Identification of monosaccharides and polysaccharides,8. Identification of anthraquinones,9. Identification of tannins,10. Identification of flavonoids,11. Application of Thin layer chromatography,12. Identification of cyanogenic glycosides,13. Identification of cardiotonic glycosides,14. Quantitative determination of total ashes and determination of foam value. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Proficiently use microscope to identify botanical drugs. | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 1.1. Recognize drugs using characteristic microscopical elements such as druses, plant tissues, glandular trichomes, etc. | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 1.2. Identify the presence of any adulteration in the identified drug material | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 2. Detect the presence of anthraquinones and tannins in plant material and/or botanical drugs using identification reactions | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 2.1. Detect the presence of flavonoids and cyanogenic glycosides in plant material and/or botanical drugs using identification reactions | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 2.2. Detect the presence of cardiotonic glycosides in plant material and/or botanical drugs using various deoxysugar identification reactions | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 3. Perform qualitative and quantitative analyses of biologically active substances in plant materials and/or botanical drugs using chromatographic and other similar techniques | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 3.1. Separate and identify biologically active compounds of botanical drugs using Thin Layer Chromatography (TLC) and special reagents | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| 3.2. Perform foam value determination of drugs containing saponins | 10, 12, 14, 16, 17, 19, 5, 8, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 5: Cooperative Learning, 8: Flipped Classroom Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1. Demostration | 1, 2, 3, 4 |
| 2 | 2. Microscopic examination of pulverized drugs 1 | 1, 2, 3, 4 |
| 3 | 3. Microscopic examination of pulverized drugs 2 | 1, 2, 3, 4 |
| 4 | 4. Microscopic examination of pulverized drugs 3 | 1, 2, 3, 4 |
| 5 | 5. Microscopic examination of pulverized drugs 4 | 1, 2, 3, 4 |
| 6 | 6. Microscopic examination of pulverized drugs 5 | 1, 2, 3, 4 |
| 7 | 7. Identification of monosaccharides and polysaccharides | 1, 2, 3, 4 |
| 8 | 8. Identification of anthraquinones | 1, 2, 3, 4 |
| 9 | 9. Identification of tannins | 1, 2, 3, 4 |
| 10 | 10. Identification of flavonoids | 1, 2, 3, 4 |
| 11 | 11. Application of Thin layer chromatography | 1, 2, 3, 4 |
| 12 | 12. Identification of cyanogenic glycosides | 1, 2, 3, 4 |
| 13 | 13. Identification of cardiotonic glycosides | 1, 2, 3, 4 |
| 14 | 14. Quantitative determination of total ashes and determination of foam value | 1, 2, 3, 4 |
| Resources |
| 1- Pharmacognosy 1 Laboratory lecture notes will be provided to students. 2- Upton, R., Graff, A., Jolliffe, G., Williamson, E. (2011) American Herbal Pharmacopoeia Botanical Pharmacognosy - Microscopic Characterization of Botanical Medicines, CRC Press aylor&Francis Group 3- Wagner, H. And Bladt, S. (2009) Plant Drug Analysis: A Thin Layer Chromatgraphy Atlas 2nd Ed. Springer 4- Jackson, B. P., Snowdon, D. W. (2019) eBook Atlas of Microscopy of Medicinal Plants, Culinary Herbs and Spices CBS Publishers & Distributors 5- Heinrich, M. (2012) Fundamentals of Pharmacognosy and Phytotherapy 2Ed. Elsevier Health Sciences |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | ||||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | ||||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |