Course Description
Course | Code | Semester | T+P (Hour) | Credit | ECTS |
---|---|---|---|---|---|
DRUG INTERACTIONS | - | Spring Semester | 2+0 | 2 | 3 |
Course Program |
Prerequisites Courses | |
Recommended Elective Courses |
Language of Course | Turkish |
Course Level | First Cycle (Bachelor's Degree) |
Course Type | Elective |
Course Coordinator | Assist.Prof. Büşra Nur ÇATTIK |
Name of Lecturer(s) | Assist.Prof. Rashıda Muhammad UMAR, Assist.Prof. Neda TANER, Assist.Prof. Büşra Nur ÇATTIK |
Assistant(s) | |
Aim | The aim of this course is to inform about drug interactions that is as a change in the pharmacologic effect of a therapeutic drug that results when it is given concurrently with another drug or with food. |
Course Content | This course contains; Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions,CYP enzyme family and the drugs that induct and inhibit CYPs,Importance of drug-drug interactions and drug side/adverse effects statement,Alcohol interactions, food interactions,Antibacterial and antiviral drug interactions,Antihipertansive drug interactions,Antiarrhytmic and digital glycoside drug interactions,Antianginal, anticoagulant drug interactions,Analgesic and non-steroidal antiinflammatory drug interactions,Immunosuppressive drug interactions,Anticonvulsant drug interactions,Neuroleptic, anxiolytic, hypnotic drug interactions,Antidepressant and oral-contraseptive drug interactions,Interactions with herbals. |
Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
1. Categorized mechanisms of the drug interactions | 16, 4, 9 | A |
1.1. Describe pharmacokinetic interactions | 16, 4, 9 | A |
1.2. Describe pharmacodynamics interactions | 16, 4, 9 | A, G |
2. Explain the importance of pharmacovigilance | 16, 4, 9 | A |
2.1. List tasks of Turkey Pharmacavigilance Center | 16, 4, 9 | A |
2.2. Define the adverse effects, adverse events etc | 16, 4, 9 | A |
2.3. Explain the role of a pharmacist about pharmacovigilance | 16, 4, 9 | A |
3. Categorized drug-drug interactions | 16, 4, 9 | A |
3.1. Exemplify drug-drug interactions | 16, 4, 9 | A |
3.2. List the points to take into consideration to prevent drug-drug interactions | 16, 4, 9 | A |
3.3. List the duties of the pharmacist to prevent drug-drug interactions | 16, 4, 9 | A |
4. Evaluated drug-food interactions | 16, 4, 9 | A |
4.1. Explain drug-food interactions | 16, 4, 9 | A |
4.2. List the points to take into consideration to prevent drug-food interactions | 16, 4, 9 | A |
Teaching Methods: | 16: Question - Answer Technique, 4: Inquiry-Based Learning, 9: Lecture Method |
Assessment Methods: | A: Traditional Written Exam, G: Quiz |
Course Outline
Order | Subjects | Preliminary Work |
---|---|---|
1 | Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions | 1, 2, 3 |
2 | CYP enzyme family and the drugs that induct and inhibit CYPs | 1, 2, 3 |
3 | Importance of drug-drug interactions and drug side/adverse effects statement | 1, 2, 3 |
4 | Alcohol interactions, food interactions | 1, 2, 3 |
5 | Antibacterial and antiviral drug interactions | 1, 2, 3 |
6 | Antihipertansive drug interactions | 1, 2, 3 |
7 | Antiarrhytmic and digital glycoside drug interactions | 1, 2, 3 |
8 | Antianginal, anticoagulant drug interactions | 1, 2, 3 |
9 | Analgesic and non-steroidal antiinflammatory drug interactions | 1, 2, 3 |
10 | Immunosuppressive drug interactions | 1, 2, 3 |
11 | Anticonvulsant drug interactions | 1, 2, 3 |
12 | Neuroleptic, anxiolytic, hypnotic drug interactions | 1, 2, 3 |
13 | Antidepressant and oral-contraseptive drug interactions | 1, 2, 3 |
14 | Interactions with herbals | 1, 2, 3 |
Resources |
1. Lecture notes 2. Book: Baxter K, Stockleys Drug Interactions (9th ed), Pharmaceutical Press (2010). 3. Online source: uptodate.com |
Medscape online drug information system TEB Rx drug information system |
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications | |||||||
No | Program Qualification | Contribution Level | |||||
1 | 2 | 3 | 4 | 5 | |||
1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
14 | PQ-14. Record and document all professional activities and applications. | X | |||||
15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X |
Assessment Methods
Contribution Level | Absolute Evaluation | |
Rate of Midterm Exam to Success | 40 | |
Rate of Final Exam to Success | 60 | |
Total | 100 |
ECTS / Workload Table | ||||||
Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
Course Hours | 14 | 2 | 28 | |||
Guided Problem Solving | 0 | 0 | 0 | |||
Resolution of Homework Problems and Submission as a Report | 7 | 2 | 14 | |||
Term Project | 0 | 0 | 0 | |||
Presentation of Project / Seminar | 1 | 2 | 2 | |||
Quiz | 0 | 0 | 0 | |||
Midterm Exam | 7 | 2 | 14 | |||
General Exam | 14 | 2 | 28 | |||
Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
Total Workload(Hour) | 86 | |||||
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(86/30) | 3 | |||||
ECTS of the course: 30 hours of work is counted as 1 ECTS credit. |
Detail Informations of the Course
Course Description
Course | Code | Semester | T+P (Hour) | Credit | ECTS |
---|---|---|---|---|---|
DRUG INTERACTIONS | - | Spring Semester | 2+0 | 2 | 3 |
Course Program |
Prerequisites Courses | |
Recommended Elective Courses |
Language of Course | Turkish |
Course Level | First Cycle (Bachelor's Degree) |
Course Type | Elective |
Course Coordinator | Assist.Prof. Büşra Nur ÇATTIK |
Name of Lecturer(s) | Assist.Prof. Rashıda Muhammad UMAR, Assist.Prof. Neda TANER, Assist.Prof. Büşra Nur ÇATTIK |
Assistant(s) | |
Aim | The aim of this course is to inform about drug interactions that is as a change in the pharmacologic effect of a therapeutic drug that results when it is given concurrently with another drug or with food. |
Course Content | This course contains; Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions,CYP enzyme family and the drugs that induct and inhibit CYPs,Importance of drug-drug interactions and drug side/adverse effects statement,Alcohol interactions, food interactions,Antibacterial and antiviral drug interactions,Antihipertansive drug interactions,Antiarrhytmic and digital glycoside drug interactions,Antianginal, anticoagulant drug interactions,Analgesic and non-steroidal antiinflammatory drug interactions,Immunosuppressive drug interactions,Anticonvulsant drug interactions,Neuroleptic, anxiolytic, hypnotic drug interactions,Antidepressant and oral-contraseptive drug interactions,Interactions with herbals. |
Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
1. Categorized mechanisms of the drug interactions | 16, 4, 9 | A |
1.1. Describe pharmacokinetic interactions | 16, 4, 9 | A |
1.2. Describe pharmacodynamics interactions | 16, 4, 9 | A, G |
2. Explain the importance of pharmacovigilance | 16, 4, 9 | A |
2.1. List tasks of Turkey Pharmacavigilance Center | 16, 4, 9 | A |
2.2. Define the adverse effects, adverse events etc | 16, 4, 9 | A |
2.3. Explain the role of a pharmacist about pharmacovigilance | 16, 4, 9 | A |
3. Categorized drug-drug interactions | 16, 4, 9 | A |
3.1. Exemplify drug-drug interactions | 16, 4, 9 | A |
3.2. List the points to take into consideration to prevent drug-drug interactions | 16, 4, 9 | A |
3.3. List the duties of the pharmacist to prevent drug-drug interactions | 16, 4, 9 | A |
4. Evaluated drug-food interactions | 16, 4, 9 | A |
4.1. Explain drug-food interactions | 16, 4, 9 | A |
4.2. List the points to take into consideration to prevent drug-food interactions | 16, 4, 9 | A |
Teaching Methods: | 16: Question - Answer Technique, 4: Inquiry-Based Learning, 9: Lecture Method |
Assessment Methods: | A: Traditional Written Exam, G: Quiz |
Course Outline
Order | Subjects | Preliminary Work |
---|---|---|
1 | Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions | 1, 2, 3 |
2 | CYP enzyme family and the drugs that induct and inhibit CYPs | 1, 2, 3 |
3 | Importance of drug-drug interactions and drug side/adverse effects statement | 1, 2, 3 |
4 | Alcohol interactions, food interactions | 1, 2, 3 |
5 | Antibacterial and antiviral drug interactions | 1, 2, 3 |
6 | Antihipertansive drug interactions | 1, 2, 3 |
7 | Antiarrhytmic and digital glycoside drug interactions | 1, 2, 3 |
8 | Antianginal, anticoagulant drug interactions | 1, 2, 3 |
9 | Analgesic and non-steroidal antiinflammatory drug interactions | 1, 2, 3 |
10 | Immunosuppressive drug interactions | 1, 2, 3 |
11 | Anticonvulsant drug interactions | 1, 2, 3 |
12 | Neuroleptic, anxiolytic, hypnotic drug interactions | 1, 2, 3 |
13 | Antidepressant and oral-contraseptive drug interactions | 1, 2, 3 |
14 | Interactions with herbals | 1, 2, 3 |
Resources |
1. Lecture notes 2. Book: Baxter K, Stockleys Drug Interactions (9th ed), Pharmaceutical Press (2010). 3. Online source: uptodate.com |
Medscape online drug information system TEB Rx drug information system |
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications | |||||||
No | Program Qualification | Contribution Level | |||||
1 | 2 | 3 | 4 | 5 | |||
1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
14 | PQ-14. Record and document all professional activities and applications. | X | |||||
15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X |
Assessment Methods
Contribution Level | Absolute Evaluation | |
Rate of Midterm Exam to Success | 40 | |
Rate of Final Exam to Success | 60 | |
Total | 100 |