Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| DRUG INTERACTIONS | - | Fall Semester | 2+0 | 2 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Büşra Nur ÇATTIK |
| Name of Lecturer(s) | Assist.Prof. Rashıda Muhammad UMAR, Assist.Prof. Neda TANER, Assist.Prof. Büşra Nur ÇATTIK |
| Assistant(s) | |
| Aim | The aim of this course is to inform about drug interactions that is as a change in the pharmacologic effect of a therapeutic drug that results when it is given concurrently with another drug or with food. |
| Course Content | This course contains; Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions,CYP enzyme family and the drugs that induct and inhibit CYPs,Importance of drug-drug interactions and drug side/adverse effects statement,Alcohol interactions, food interactions,Antibacterial and antiviral drug interactions,Antihipertansive drug interactions,Antiarrhytmic and digital glycoside drug interactions,Antianginal, anticoagulant drug interactions,Analgesic and non-steroidal antiinflammatory drug interactions,Immunosuppressive drug interactions,Anticonvulsant drug interactions,Neuroleptic, anxiolytic, hypnotic drug interactions,Antidepressant and oral-contraseptive drug interactions,Interactions with herbals. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Categorized mechanisms of the drug interactions | 16, 4, 9 | A |
| 1.1. Describe pharmacokinetic interactions | 16, 4, 9 | A |
| 1.2. Describe pharmacodynamics interactions | 16, 4, 9 | A, G |
| 2. Explain the importance of pharmacovigilance | 16, 4, 9 | A |
| 2.1. List tasks of Turkey Pharmacavigilance Center | 16, 4, 9 | A |
| 2.2. Define the adverse effects, adverse events etc | 16, 4, 9 | A |
| 2.3. Explain the role of a pharmacist about pharmacovigilance | 16, 4, 9 | A |
| 3. Categorized drug-drug interactions | 16, 4, 9 | A |
| 3.1. Exemplify drug-drug interactions | 16, 4, 9 | A |
| 3.2. List the points to take into consideration to prevent drug-drug interactions | 16, 4, 9 | A |
| 3.3. List the duties of the pharmacist to prevent drug-drug interactions | 16, 4, 9 | A |
| 4. Evaluated drug-food interactions | 16, 4, 9 | A |
| 4.1. Explain drug-food interactions | 16, 4, 9 | A |
| 4.2. List the points to take into consideration to prevent drug-food interactions | 16, 4, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 4: Inquiry-Based Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions | 1, 2, 3 |
| 2 | CYP enzyme family and the drugs that induct and inhibit CYPs | 1, 2, 3 |
| 3 | Importance of drug-drug interactions and drug side/adverse effects statement | 1, 2, 3 |
| 4 | Alcohol interactions, food interactions | 1, 2, 3 |
| 5 | Antibacterial and antiviral drug interactions | 1, 2, 3 |
| 6 | Antihipertansive drug interactions | 1, 2, 3 |
| 7 | Antiarrhytmic and digital glycoside drug interactions | 1, 2, 3 |
| 8 | Antianginal, anticoagulant drug interactions | 1, 2, 3 |
| 9 | Analgesic and non-steroidal antiinflammatory drug interactions | 1, 2, 3 |
| 10 | Immunosuppressive drug interactions | 1, 2, 3 |
| 11 | Anticonvulsant drug interactions | 1, 2, 3 |
| 12 | Neuroleptic, anxiolytic, hypnotic drug interactions | 1, 2, 3 |
| 13 | Antidepressant and oral-contraseptive drug interactions | 1, 2, 3 |
| 14 | Interactions with herbals | 1, 2, 3 |
| Resources |
| 1. Lecture notes 2. Book: Baxter K, Stockleys Drug Interactions (9th ed), Pharmaceutical Press (2010). 3. Online source: uptodate.com |
| Medscape online drug information system TEB Rx drug information system |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 7 | 2 | 14 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 1 | 2 | 2 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 7 | 2 | 14 | |||
| General Exam | 14 | 2 | 28 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 86 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(86/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| DRUG INTERACTIONS | - | Fall Semester | 2+0 | 2 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Büşra Nur ÇATTIK |
| Name of Lecturer(s) | Assist.Prof. Rashıda Muhammad UMAR, Assist.Prof. Neda TANER, Assist.Prof. Büşra Nur ÇATTIK |
| Assistant(s) | |
| Aim | The aim of this course is to inform about drug interactions that is as a change in the pharmacologic effect of a therapeutic drug that results when it is given concurrently with another drug or with food. |
| Course Content | This course contains; Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions,CYP enzyme family and the drugs that induct and inhibit CYPs,Importance of drug-drug interactions and drug side/adverse effects statement,Alcohol interactions, food interactions,Antibacterial and antiviral drug interactions,Antihipertansive drug interactions,Antiarrhytmic and digital glycoside drug interactions,Antianginal, anticoagulant drug interactions,Analgesic and non-steroidal antiinflammatory drug interactions,Immunosuppressive drug interactions,Anticonvulsant drug interactions,Neuroleptic, anxiolytic, hypnotic drug interactions,Antidepressant and oral-contraseptive drug interactions,Interactions with herbals. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. Categorized mechanisms of the drug interactions | 16, 4, 9 | A |
| 1.1. Describe pharmacokinetic interactions | 16, 4, 9 | A |
| 1.2. Describe pharmacodynamics interactions | 16, 4, 9 | A, G |
| 2. Explain the importance of pharmacovigilance | 16, 4, 9 | A |
| 2.1. List tasks of Turkey Pharmacavigilance Center | 16, 4, 9 | A |
| 2.2. Define the adverse effects, adverse events etc | 16, 4, 9 | A |
| 2.3. Explain the role of a pharmacist about pharmacovigilance | 16, 4, 9 | A |
| 3. Categorized drug-drug interactions | 16, 4, 9 | A |
| 3.1. Exemplify drug-drug interactions | 16, 4, 9 | A |
| 3.2. List the points to take into consideration to prevent drug-drug interactions | 16, 4, 9 | A |
| 3.3. List the duties of the pharmacist to prevent drug-drug interactions | 16, 4, 9 | A |
| 4. Evaluated drug-food interactions | 16, 4, 9 | A |
| 4.1. Explain drug-food interactions | 16, 4, 9 | A |
| 4.2. List the points to take into consideration to prevent drug-food interactions | 16, 4, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 4: Inquiry-Based Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Mechanisms of drug interactions: Pharmacokinetic and Pharmacodynamic interactions | 1, 2, 3 |
| 2 | CYP enzyme family and the drugs that induct and inhibit CYPs | 1, 2, 3 |
| 3 | Importance of drug-drug interactions and drug side/adverse effects statement | 1, 2, 3 |
| 4 | Alcohol interactions, food interactions | 1, 2, 3 |
| 5 | Antibacterial and antiviral drug interactions | 1, 2, 3 |
| 6 | Antihipertansive drug interactions | 1, 2, 3 |
| 7 | Antiarrhytmic and digital glycoside drug interactions | 1, 2, 3 |
| 8 | Antianginal, anticoagulant drug interactions | 1, 2, 3 |
| 9 | Analgesic and non-steroidal antiinflammatory drug interactions | 1, 2, 3 |
| 10 | Immunosuppressive drug interactions | 1, 2, 3 |
| 11 | Anticonvulsant drug interactions | 1, 2, 3 |
| 12 | Neuroleptic, anxiolytic, hypnotic drug interactions | 1, 2, 3 |
| 13 | Antidepressant and oral-contraseptive drug interactions | 1, 2, 3 |
| 14 | Interactions with herbals | 1, 2, 3 |
| Resources |
| 1. Lecture notes 2. Book: Baxter K, Stockleys Drug Interactions (9th ed), Pharmaceutical Press (2010). 3. Online source: uptodate.com |
| Medscape online drug information system TEB Rx drug information system |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | ||||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | ||||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | ||||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | ||||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |