Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL CHEMISTRY II | - | Spring Semester | 3+0 | 3 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Seda ÜNSALAN |
| Name of Lecturer(s) | |
| Assistant(s) | |
| Aim | To evaluate the structure-activity relationships, chemical structures, synthesis and analysis of the drugs effecting on central nervous system. |
| Course Content | This course contains; 1. General properties of the drugs effecting on central nervous system and general anasthetic drugs,2. Sedative and hypnotics,3. Tranquilizers,4. Neuroleptics,5. Antidepressants: Tricyclics,6. Antidepressants: MAO Inhibitors,7. Antidepressants: Serotonin reuptake inhibitors,8. Psychomimetics, analeptics,9. Skeletal muscle relaxants,10. Antiepileptics,11. Narcotic analgesics,12. Antitussive-expectorants,13. Nonnarcotic analgesics,14. Local anesthetics. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. will be able to evaluate the drugs effecting on central nervous system. | 19, 9 | A |
| 1.1. list the structures and synthesis of the general anasthetic drugs. | 19, 9 | A |
| 1.2. exemine the structure-activity relationships of sedative-hypnotic drugs. | 19, 9 | A |
| 1.3. explain the synthesis and analyses of sedative-hypnotic drugs. | 19, 9 | A |
| 2. will be able to debate the psychopharmaceutical drugs. | 19, 9 | A |
| 2.1. examine the structure-activity relationships of tranquilizers. | 19, 9 | A |
| 2.2. debate the structure-activity relationships of neuroleptics. | 19, 9 | A |
| 2.3. report the chemical structures, synthesis and analysis of the tranquilizers and neuroleptics. | 19, 9 | A |
| 3. will be able to classify the antidepressant drugs. | 19, 9 | A |
| 3.1. explain the structure-activity relationships and chemical properties of tricyclic antidepressant drugs. | 19, 9 | A |
| 3.2. assess the structure-activity relationships and chemical properties of MAO inhibitory antidepressant drugs. | 19, 9 | A |
| 3.3. explain the structure-activity relationships and chemical properties of serotonin reuptake inhibitory antidepressant drugs. | 19, 9 | A |
| 4. will be able to compare the structure-activity relationships and chemical properties of antiepileptics and skeletal muscle relaxants. | 19, 9 | A |
| 4.1. explain the structure-activity relationships and chemical properties of skeletal muscle relaxants. | 19, 9 | A |
| 4.2. summarize the structure-activity relationships and chemical properties of antiepileptics. | 19, 9 | A |
| 5. will be able to discuss the structure-activity relationships of analgesics. | 19, 9 | A |
| 5.1. debate the structure-activity relationships and chemical properties of narcotic analgesics. | 19, 9 | A |
| 5.2. evaluate the structure-activity relationships and chemical properties of nonnarcotic analgesics. | 19, 9 | A |
| 5.3. explain the structure-activity relationships and chemical properties of local anasthetics. | 19, 9 | A |
| Teaching Methods: | 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1. General properties of the drugs effecting on central nervous system and general anasthetic drugs | 1 |
| 2 | 2. Sedative and hypnotics | 1 |
| 3 | 3. Tranquilizers | 1 |
| 4 | 4. Neuroleptics | 1 |
| 5 | 5. Antidepressants: Tricyclics | 1 |
| 6 | 6. Antidepressants: MAO Inhibitors | 1 |
| 7 | 7. Antidepressants: Serotonin reuptake inhibitors | 1 |
| 8 | 8. Psychomimetics, analeptics | 1 |
| 9 | 9. Skeletal muscle relaxants | 1 |
| 10 | 10. Antiepileptics | 1 |
| 11 | 11. Narcotic analgesics | 1 |
| 12 | 12. Antitussive-expectorants | 1 |
| 13 | 13. Nonnarcotic analgesics | 1 |
| 14 | 14. Local anesthetics | 1 |
| Resources |
| Pharmaceutical Chemistry II notes will be given to the students. |
| 1. Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı Öğretim Üyeleri. (2004) Farmasötik Kimya. Hacettepe Üniversitesi Yayınları, Ankara. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 14 | 3 | 42 | |||
| Resolution of Homework Problems and Submission as a Report | 14 | 2 | 28 | |||
| Term Project | 5 | 2 | 10 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 7 | 2 | 14 | |||
| General Exam | 7 | 2 | 14 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 150 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(150/30) | 5 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL CHEMISTRY II | - | Spring Semester | 3+0 | 3 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Seda ÜNSALAN |
| Name of Lecturer(s) | |
| Assistant(s) | |
| Aim | To evaluate the structure-activity relationships, chemical structures, synthesis and analysis of the drugs effecting on central nervous system. |
| Course Content | This course contains; 1. General properties of the drugs effecting on central nervous system and general anasthetic drugs,2. Sedative and hypnotics,3. Tranquilizers,4. Neuroleptics,5. Antidepressants: Tricyclics,6. Antidepressants: MAO Inhibitors,7. Antidepressants: Serotonin reuptake inhibitors,8. Psychomimetics, analeptics,9. Skeletal muscle relaxants,10. Antiepileptics,11. Narcotic analgesics,12. Antitussive-expectorants,13. Nonnarcotic analgesics,14. Local anesthetics. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. will be able to evaluate the drugs effecting on central nervous system. | 19, 9 | A |
| 1.1. list the structures and synthesis of the general anasthetic drugs. | 19, 9 | A |
| 1.2. exemine the structure-activity relationships of sedative-hypnotic drugs. | 19, 9 | A |
| 1.3. explain the synthesis and analyses of sedative-hypnotic drugs. | 19, 9 | A |
| 2. will be able to debate the psychopharmaceutical drugs. | 19, 9 | A |
| 2.1. examine the structure-activity relationships of tranquilizers. | 19, 9 | A |
| 2.2. debate the structure-activity relationships of neuroleptics. | 19, 9 | A |
| 2.3. report the chemical structures, synthesis and analysis of the tranquilizers and neuroleptics. | 19, 9 | A |
| 3. will be able to classify the antidepressant drugs. | 19, 9 | A |
| 3.1. explain the structure-activity relationships and chemical properties of tricyclic antidepressant drugs. | 19, 9 | A |
| 3.2. assess the structure-activity relationships and chemical properties of MAO inhibitory antidepressant drugs. | 19, 9 | A |
| 3.3. explain the structure-activity relationships and chemical properties of serotonin reuptake inhibitory antidepressant drugs. | 19, 9 | A |
| 4. will be able to compare the structure-activity relationships and chemical properties of antiepileptics and skeletal muscle relaxants. | 19, 9 | A |
| 4.1. explain the structure-activity relationships and chemical properties of skeletal muscle relaxants. | 19, 9 | A |
| 4.2. summarize the structure-activity relationships and chemical properties of antiepileptics. | 19, 9 | A |
| 5. will be able to discuss the structure-activity relationships of analgesics. | 19, 9 | A |
| 5.1. debate the structure-activity relationships and chemical properties of narcotic analgesics. | 19, 9 | A |
| 5.2. evaluate the structure-activity relationships and chemical properties of nonnarcotic analgesics. | 19, 9 | A |
| 5.3. explain the structure-activity relationships and chemical properties of local anasthetics. | 19, 9 | A |
| Teaching Methods: | 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1. General properties of the drugs effecting on central nervous system and general anasthetic drugs | 1 |
| 2 | 2. Sedative and hypnotics | 1 |
| 3 | 3. Tranquilizers | 1 |
| 4 | 4. Neuroleptics | 1 |
| 5 | 5. Antidepressants: Tricyclics | 1 |
| 6 | 6. Antidepressants: MAO Inhibitors | 1 |
| 7 | 7. Antidepressants: Serotonin reuptake inhibitors | 1 |
| 8 | 8. Psychomimetics, analeptics | 1 |
| 9 | 9. Skeletal muscle relaxants | 1 |
| 10 | 10. Antiepileptics | 1 |
| 11 | 11. Narcotic analgesics | 1 |
| 12 | 12. Antitussive-expectorants | 1 |
| 13 | 13. Nonnarcotic analgesics | 1 |
| 14 | 14. Local anesthetics | 1 |
| Resources |
| Pharmaceutical Chemistry II notes will be given to the students. |
| 1. Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya Anabilim Dalı Öğretim Üyeleri. (2004) Farmasötik Kimya. Hacettepe Üniversitesi Yayınları, Ankara. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |