Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL CHEMISTRY LAB. II | - | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Seda ÜNSALAN |
| Name of Lecturer(s) | |
| Assistant(s) | |
| Aim | The aims of this course are to synthesize of certain organic and pharmaceutical active substances, to study of mechanisms of organic reactions, separation and purification procedures, to show computational drug design methods |
| Course Content | This course contains; Introduction of Separation and purification process,The extraction, distillation and crystallization,Physical separation methods, electrophoresis, chromatography,Some organic and drug Separation and purification of the active substance,Some organic and drug separation and purification of the active substance,Separation of Cannizaro reaction products,refractometric and polarimetric methods,Isolation of the active agent formulation in use,Isolation of active ingredient from the formulations in use,Column chromatography,Column chromatography application,Recognition of computerized drug design methods,Molecular modeling study I,Molecular modeling study II. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. analyse the separation and purification methods of the synthesized compounds. | 12, 14, 16, 17, 9 | A |
| 1.1. describe the necessary equipment for the seperation and purification methods | 12, 14, 16, 17, 9 | |
| 1.2. use the necessary equipment fort he seperation ande purification methods. | 12, 14, 16, 17, 9 | A |
| 2. will be able to apply polarimetric and refractometric methods | 12, 14, 16, 17, 9 | A |
| 2.1. describe the necessary equipment for polarimetric and refractometric methods. | 12, 14, 16, 17, 9 | A |
| 2.2. use the necessary equipment for polarimetric and refratometric methods. | 12, 14, 16, 17, 9 | A |
| 3. will be able to apply colon chromotgraphy | 12, 14, 16, 17, 9 | A |
| 3.1. describe the necessary equipment for the colon chromotography | 12, 14, 16, 17, 9 | A |
| 3.2. use the necessary equipment for the colon chromotography | 12, 14, 16, 17, 9 | A |
| 4. analyse computer drug design methods. | 12, 14, 16, 17, 9 | A |
| 4.1. describe the molecular modelling technique | 12, 14, 16, 17, 9 | A |
| 4.2 .use the molecular modelling technique | 12, 14, 16, 17, 9 | A |
| Teaching Methods: | 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction of Separation and purification process | 1 |
| 2 | The extraction, distillation and crystallization | 1 |
| 3 | Physical separation methods, electrophoresis, chromatography | 1 |
| 4 | Some organic and drug Separation and purification of the active substance | 1 |
| 5 | Some organic and drug separation and purification of the active substance | 1 |
| 6 | Separation of Cannizaro reaction products | 1 |
| 7 | refractometric and polarimetric methods | 1 |
| 8 | Isolation of the active agent formulation in use | 1 |
| 9 | Isolation of active ingredient from the formulations in use | 1 |
| 10 | Column chromatography | 1 |
| 11 | Column chromatography application | 1 |
| 12 | Recognition of computerized drug design methods | 1 |
| 13 | Molecular modeling study I | 1 |
| 14 | Molecular modeling study II | 1 |
| Resources |
| 1. The laboratory notes will be given to the students. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 14 | 3 | 42 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 3 | 3 | |||
| General Exam | 1 | 3 | 3 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 90 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(90/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL CHEMISTRY LAB. II | - | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Seda ÜNSALAN |
| Name of Lecturer(s) | |
| Assistant(s) | |
| Aim | The aims of this course are to synthesize of certain organic and pharmaceutical active substances, to study of mechanisms of organic reactions, separation and purification procedures, to show computational drug design methods |
| Course Content | This course contains; Introduction of Separation and purification process,The extraction, distillation and crystallization,Physical separation methods, electrophoresis, chromatography,Some organic and drug Separation and purification of the active substance,Some organic and drug separation and purification of the active substance,Separation of Cannizaro reaction products,refractometric and polarimetric methods,Isolation of the active agent formulation in use,Isolation of active ingredient from the formulations in use,Column chromatography,Column chromatography application,Recognition of computerized drug design methods,Molecular modeling study I,Molecular modeling study II. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. analyse the separation and purification methods of the synthesized compounds. | 12, 14, 16, 17, 9 | A |
| 1.1. describe the necessary equipment for the seperation and purification methods | 12, 14, 16, 17, 9 | |
| 1.2. use the necessary equipment fort he seperation ande purification methods. | 12, 14, 16, 17, 9 | A |
| 2. will be able to apply polarimetric and refractometric methods | 12, 14, 16, 17, 9 | A |
| 2.1. describe the necessary equipment for polarimetric and refractometric methods. | 12, 14, 16, 17, 9 | A |
| 2.2. use the necessary equipment for polarimetric and refratometric methods. | 12, 14, 16, 17, 9 | A |
| 3. will be able to apply colon chromotgraphy | 12, 14, 16, 17, 9 | A |
| 3.1. describe the necessary equipment for the colon chromotography | 12, 14, 16, 17, 9 | A |
| 3.2. use the necessary equipment for the colon chromotography | 12, 14, 16, 17, 9 | A |
| 4. analyse computer drug design methods. | 12, 14, 16, 17, 9 | A |
| 4.1. describe the molecular modelling technique | 12, 14, 16, 17, 9 | A |
| 4.2 .use the molecular modelling technique | 12, 14, 16, 17, 9 | A |
| Teaching Methods: | 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction of Separation and purification process | 1 |
| 2 | The extraction, distillation and crystallization | 1 |
| 3 | Physical separation methods, electrophoresis, chromatography | 1 |
| 4 | Some organic and drug Separation and purification of the active substance | 1 |
| 5 | Some organic and drug separation and purification of the active substance | 1 |
| 6 | Separation of Cannizaro reaction products | 1 |
| 7 | refractometric and polarimetric methods | 1 |
| 8 | Isolation of the active agent formulation in use | 1 |
| 9 | Isolation of active ingredient from the formulations in use | 1 |
| 10 | Column chromatography | 1 |
| 11 | Column chromatography application | 1 |
| 12 | Recognition of computerized drug design methods | 1 |
| 13 | Molecular modeling study I | 1 |
| 14 | Molecular modeling study II | 1 |
| Resources |
| 1. The laboratory notes will be given to the students. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |