Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOLOGY I | - | Spring Semester | 2+0 | 2 | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Çağlar MACİT |
| Name of Lecturer(s) | Assist.Prof. Çağlar MACİT, Prof.Dr. Hatice Kübra ELÇİOĞLU |
| Assistant(s) | |
| Aim | To teach the basic pharmacology, pharmacokinetics and pharmacodyamics, drug toxicity, drug abuse, pharmacogenetic, pharmacovigilance and its importance, and chemotherapeutics and their mechanism of action. |
| Course Content | This course contains; Introduction to Pharmacology, Routes of administration,Absorption, Distribution, Drug biotransformation and excretion, mechanisms of drug actions,Dose-concentration-effect relationship,Receptors, Drug-Receptor relationship, factors that change the drug effect,Pharmacodynamic and pharmacokinetic drug interactions, Drug toxicity,Pharmacogenetic,Pharmacovigilance,Chemotherapeutics, betalactams, macrolides,Lincosamide, chloramphenicol, tetracyclines, aminoglycosides,Narrow spectum antistaphilococcus and antianaerobs, sulfonamides and fluoroquinolones ,Antiviral drugs,Immunemodulator drugs, antifungals, antiprotozals, antihelmintics,Antineoplastics. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. evaluate the basic subjects of the pharmacology. | 16, 9 | C |
| 1.1. identify the functions of the drug pharmacokinetics and pharmacodynamics. | 16, 9 | C |
| 1.2. explain the functions of drug pharmacokinetics and pharmacodynamics. | 16, 9 | C |
| 1.3. summarize the drugs pharmacokinetics and pharmacodynamics. | 16, 9 | C |
| 2. evaluate the drug toxicity and addiction. | 16, 9 | C |
| 2.1. identify the drug toxicity and abuse. | 16, 9 | C |
| 2.2. explain the drug toxicity and their mechanism. | 16, 9 | C |
| 3. Explain the pharmacogenetic | 16, 9 | C |
| 4. Explain the pharmacovigilance. | 16, 9 | C |
| 4.1. Know the importance of pharmacovigilance. | 16, 9 | C |
| 5. Know the chemotherapeutic drugs. | 16, 9 | C |
| 5.1. Know the subtypes of the chemotherapeutic drugs. | 16, 9 | C |
| 5.2. Know and explain the mechanism of action of chemotherapeutic drugs. | 16, 9 | C |
| Teaching Methods: | 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | C: Multiple-Choice Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to Pharmacology, Routes of administration | 1, 2, 3 |
| 2 | Absorption, Distribution, Drug biotransformation and excretion, mechanisms of drug actions | 1, 2, 3 |
| 3 | Dose-concentration-effect relationship | 1, 2, 3 |
| 4 | Receptors, Drug-Receptor relationship, factors that change the drug effect | 1, 2, 3 |
| 5 | Pharmacodynamic and pharmacokinetic drug interactions | 1, 2, 3 |
| 6 | Drug toxicity | 1, 2, 3 |
| 7 | Pharmacogenetic | 1, 2, 3 |
| 8 | Pharmacovigilance | 1, 2, 3 |
| 9 | Chemotherapeutics, betalactams, macrolides | 1, 2, 3 |
| 10 | Lincosamide, chloramphenicol, tetracyclines, aminoglycosides | 1, 2, 3 |
| 11 | Narrow spectum antistaphilococcus and antianaerobs, sulfonamides and fluoroquinolones | 1, 2, 3 |
| 12 | Antiviral drugs | 1, 2, 3 |
| 13 | Immunemodulator drugs, antifungals, antiprotozals, antihelmintics | 1, 2, 3 |
| 14 | Antineoplastics | 1, 2, 3 |
| Resources |
| 1.Kayaalp, SO: Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara, 2009. 2.Hardman JG, Limbird LE, Eds.: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, New York, 2022. 3.Katzung & Trevor: Farmakoloji, Güneş Kitabevi, 2022. |
| 1, 2, 3, and lecturer notes |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 14 | 1 | 14 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 31 | 31 | |||
| General Exam | 1 | 36 | 36 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 109 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(109/30) | 4 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOLOGY I | - | Spring Semester | 2+0 | 2 | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Çağlar MACİT |
| Name of Lecturer(s) | Assist.Prof. Çağlar MACİT, Prof.Dr. Hatice Kübra ELÇİOĞLU |
| Assistant(s) | |
| Aim | To teach the basic pharmacology, pharmacokinetics and pharmacodyamics, drug toxicity, drug abuse, pharmacogenetic, pharmacovigilance and its importance, and chemotherapeutics and their mechanism of action. |
| Course Content | This course contains; Introduction to Pharmacology, Routes of administration,Absorption, Distribution, Drug biotransformation and excretion, mechanisms of drug actions,Dose-concentration-effect relationship,Receptors, Drug-Receptor relationship, factors that change the drug effect,Pharmacodynamic and pharmacokinetic drug interactions, Drug toxicity,Pharmacogenetic,Pharmacovigilance,Chemotherapeutics, betalactams, macrolides,Lincosamide, chloramphenicol, tetracyclines, aminoglycosides,Narrow spectum antistaphilococcus and antianaerobs, sulfonamides and fluoroquinolones ,Antiviral drugs,Immunemodulator drugs, antifungals, antiprotozals, antihelmintics,Antineoplastics. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. evaluate the basic subjects of the pharmacology. | 16, 9 | C |
| 1.1. identify the functions of the drug pharmacokinetics and pharmacodynamics. | 16, 9 | C |
| 1.2. explain the functions of drug pharmacokinetics and pharmacodynamics. | 16, 9 | C |
| 1.3. summarize the drugs pharmacokinetics and pharmacodynamics. | 16, 9 | C |
| 2. evaluate the drug toxicity and addiction. | 16, 9 | C |
| 2.1. identify the drug toxicity and abuse. | 16, 9 | C |
| 2.2. explain the drug toxicity and their mechanism. | 16, 9 | C |
| 3. Explain the pharmacogenetic | 16, 9 | C |
| 4. Explain the pharmacovigilance. | 16, 9 | C |
| 4.1. Know the importance of pharmacovigilance. | 16, 9 | C |
| 5. Know the chemotherapeutic drugs. | 16, 9 | C |
| 5.1. Know the subtypes of the chemotherapeutic drugs. | 16, 9 | C |
| 5.2. Know and explain the mechanism of action of chemotherapeutic drugs. | 16, 9 | C |
| Teaching Methods: | 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | C: Multiple-Choice Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to Pharmacology, Routes of administration | 1, 2, 3 |
| 2 | Absorption, Distribution, Drug biotransformation and excretion, mechanisms of drug actions | 1, 2, 3 |
| 3 | Dose-concentration-effect relationship | 1, 2, 3 |
| 4 | Receptors, Drug-Receptor relationship, factors that change the drug effect | 1, 2, 3 |
| 5 | Pharmacodynamic and pharmacokinetic drug interactions | 1, 2, 3 |
| 6 | Drug toxicity | 1, 2, 3 |
| 7 | Pharmacogenetic | 1, 2, 3 |
| 8 | Pharmacovigilance | 1, 2, 3 |
| 9 | Chemotherapeutics, betalactams, macrolides | 1, 2, 3 |
| 10 | Lincosamide, chloramphenicol, tetracyclines, aminoglycosides | 1, 2, 3 |
| 11 | Narrow spectum antistaphilococcus and antianaerobs, sulfonamides and fluoroquinolones | 1, 2, 3 |
| 12 | Antiviral drugs | 1, 2, 3 |
| 13 | Immunemodulator drugs, antifungals, antiprotozals, antihelmintics | 1, 2, 3 |
| 14 | Antineoplastics | 1, 2, 3 |
| Resources |
| 1.Kayaalp, SO: Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara, 2009. 2.Hardman JG, Limbird LE, Eds.: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, New York, 2022. 3.Katzung & Trevor: Farmakoloji, Güneş Kitabevi, 2022. |
| 1, 2, 3, and lecturer notes |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | ||||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | ||||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | ||||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | ||||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |