Course Detail
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CLINICAL BIOCHEMISTRY | - | Fall Semester | 2+0 | 2 | 2 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Neslin EMEKLİ |
| Name of Lecturer(s) | Assist.Prof. Derya CANSIZ |
| Assistant(s) | |
| Aim | This course; Introduction to Biochemistry -Macromolecules, Carbohydrates, Carbohydrate metabolism, Electron transport chain (ETZ), Proteins, Topic repetition, Enzymes, Protein and amino acid breakdown, Lipids, Digestion and absorption of lipids, Fatty acid oxidation, Catabolism, Vitamins and Minerals, In the Clinical Biochemistry laboratory ; sampling, preanalytical errors and tests, Subject repetition; includes topics. Recognize laboratory measurement methods and laboratory measurement methods, Recognize blood, urine, CSF and stool analysis, Will transfer the analysis of urinary system stones, Explain hormone and mineral analysis, Anticoagulants, Issues to be considered in sample acceptance (lipemia, hemolysis, etc.) Inappropriate sample definition, sample rejection criteria, quality control, |
| Course Content | This course contains; Introduction to biochemistry - Macromolecules,carbohydrates,carbohydrate metabolism,Electron transport chain (ETC),Proteins,enzymes,Protein and amino acid breakdown,lipids,Digestion and absorption of lipids,Fatty acid oxidation,Catabolism,Vitamins and Minerals,Hormones,Sample collection, preanalytical errors and tests in laboratories. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explains the general terms of biochemistry and learns the biochemical events that occur in the cell, Understands the definition of biochemistry and the subjects within the scope of biochemistry, Summarizes the general definition of biochemical molecules and reactions, Comprehends the professional and clinical importance of biochemistry. | 10, 16, 9 | A, E |
| Defines the structure and functions of carbohydrates and comprehends their importance in the human body, Recognizes the general properties of carbohydrates and learns their classification, Understands the chemical properties of carbohydrates, Learns the experiments of recognizing carbohydrates. | 10, 16, 9 | A, E |
| Learns carbohydrate metabolism and understands the relationship of these pathways with each other. Learns carbohydrate digestion and absorption events and carbohydrate metabolism. Understands glycogen metabolism with pathways such as glycogen synthesis and destruction. Learns energy production through electron transport and oxidative phosphorylation. | 10, 16, 9 | A, E |
| Defines the structure and functions of proteins and comprehends their role in metabolism. Learns the properties of amino acids, their chemical reactions. Learns their structures such as peptides and polypeptides. Understands the properties of proteins. | 10, 16, 9 | A, E |
| Learns the structure, functions and general properties of enzymes, Understands the common features of enzymes, Learns the naming and classification of enzymes, Defines the role of enzymes in metabolic pathways. | 10, 16 | A, E |
| Understands the structure of lipids, their role in metabolic pathways and their importance in the human body, Learns the classification of lipids, the structure of fatty acids and their derivatives, Learns the digestion and absorption of lipids, Learns fatty acid metabolism and beta oxidation. | 10, 16, 9 | A, E |
| Learns the functions and importance of vitamins and minerals in metabolic reactions in living organisms, Understands the classification and structures of vitamins, Learns types of minerals, understands their importance for the human body, Understands the role of vitamins and minerals in metabolism. | 10, 16, 9 | A, E |
| Comprehends the functioning of the clinical biochemistry laboratory, has knowledge about sampling and preventing preanalytical errors, Gains knowledge about laboratory organization, rules and safety, Learns the analysis methods used in biochemistry, Understands the variables before sample collection and analysis. | 10, 16, 9 | A, E |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to biochemistry - Macromolecules | Part 1 of the 1st resource - Part 14 of the 2nd resource - Part 1 of the 3rd resource - Part 1,2 of the 4th resource - Part 1 of the 5th resource - Part 1 of the 7th resource |
| 2 | carbohydrates | Chapter 2 of the 2nd resource - Chapter 9 of the 3rd resource - Section 9,15,16 of the 4th resource - Section 2 of the 5th resource - Section 3,6 of the 7th resource |
| 3 | carbohydrate metabolism | Part 14 of reference 2 - Part 9, 15, 16, 20 of reference 4 - Part 2 of reference 5 - Part 3,6 of reference 7 |
| 4 | Electron transport chain (ETC) | Chapter 2 of the 2nd resource - Chapter 9,15,16,20 of the 4th resource - Part 2 of the 5th resource - Section 3,6 of the 7th resource transport chain (ETZ) |
| 5 | Proteins | Chapter 2 of the 2nd resource - Chapter 5,6,7 of the 4th resource - Part 2 of the 5th resource - Chapter 4 of the 7th resource |
| 6 | enzymes | Chapter 2 of Chapter 14 - Chapter 4 of Chapter 8 - Chapter 2 of Source 5 - Chapter 5 of Source 7 |
| 7 | Protein and amino acid breakdown | Chapter 2 of the 2nd resource - Chapter 5,6,7 of the 4th resource - Part 2 of the 5th resource - Chapter 4 of the 7th resource |
| 8 | lipids | Chapter 2 of resource 14 - section 11, 17, 21 of resource 4 - Section 2 of resource 5 - section 7 of resource 7 |
| 9 | Digestion and absorption of lipids | Chapter 2 of resource 14 - section 11, 17, 21 of resource 4 - Section 2 of resource 5 - section 7 of resource 7 |
| 10 | Fatty acid oxidation | Chapter 2 of resource 14 - section 11, 17, 21 of resource 4 - Section 2 of resource 5 - section 7 of resource 7 |
| 11 | Catabolism | Part 14 of the 2nd resource - Part 1,2,3 of the 4th resource - Part 2 of the 5th resource - Part 3 of the 7th resource |
| 12 | Vitamins and Minerals | Chapter 2 of Chapter 14 - Chapter 5 of Source 5 - Chapter 10 of Source 7 |
| 13 | Hormones | Chapter 2 of Chapter 14 - Chapter 4 of Chapter 23 - Chapter 5 of Chapter 4 - Chapter 9 of Source 7 |
| 14 | Sample collection, preanalytical errors and tests in laboratories | 1st resource section 5,6 - 2nd resource section 1,4,13 - 3rd resource section 1,4,20,21,22 |
| Resources |
| 1. Clinical Biochemistry, Prof. Dr. Nesrin RETIRED; Assoc. Dr. Türkan Yiğitbaşı, Medipol University 2nd Biochemistry Laboratory for Students 3rd Edition, Prof. Dr. Nesrin RETIRED; Assoc. Dr. Türkan Yiğitbaşı, Medipol University 3rd Handbook of Clinical Biochemistry (with the addition of Hematology and Serology Laboratories), Author: İdris Mehmetoğlu, Publisher: Nobel Medicine Bookstores 4. Lehninger Biochemistry Ikeleri, Authors: David L. Nelson - Michael M. Cox, Publisher: PALME PUBLISHING, Translation Editor: Y. Murat Elçin, Number of Editions: Translation from the fifth edition 5. Harper Biyokimya, Author(s): Murray, Bender, Weil, Botham, Kennely, Rodwell, Translation Editor: Prof. Dr. Gul Guner Akdogan, Prof.Dr. Biltan Ersoz, Prof. Dr. Nevbahar Turgan 6. Tietz Laboratory Tests Clinical Guide, Author: Alan H. B. WU, Translation Editor: Prof. Dr. Kaya EMERK 7. Human Biochemistry, Brand: Palme Publishing, Author: Prof. Dr. Taner ONAT |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Equipped with adequate, trustworthy and up-to-date knowledge of Physiotherapy and Rehabilitation. | X | |||||
| 2 | PQ-2. It uses the evaluation methods for healthy, disabled and individuals who require physiotherapy and plans and implements the physiotherapy program. | X | |||||
| 3 | PQ-4. Practices using knowledge and skills based on the evidence specific to the field of physiotherapy and rehabilitation. | ||||||
| 4 | PQ-4. For function and independence in the daily life activities of individuals who require physiotherapy and rehabilitation, physiotherapy applications can be carried out using appropriate technology, training and treatment equipment. | ||||||
| 5 | PQ-5. Has the ability to work independently and effectively between disciplinary and interdisciplinary in his professional practices. | X | |||||
| 6 | PQ-6. Social responsibility plays a role in consciousness, research, projects and events. | X | |||||
| 7 | PQ-7. Adopt life-time adaptation to new conditions, learning, developing new ideas, attaching importance to quality, and use information sources effectively. | X | |||||
| 8 | PQ-8. The developments in physiotherapy and rehabilitation are followed by at least one foreign language. | X | |||||
| 9 | PQ-9. Has the ability to communicate verbally and in writing in Turkish. | X | |||||
| 10 | PQ-10. Act in accordance with the legislation and professional codes of conduct in cooperation with the relevant disciplines, considering the rights and responsibilities of the task in physiotherapy and rehabilitation applications. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 1 | 14 | |||
| Guided Problem Solving | 14 | 1 | 14 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 10 | 10 | |||
| General Exam | 1 | 15 | 15 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 53 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(53/30) | 2 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CLINICAL BIOCHEMISTRY | - | Fall Semester | 2+0 | 2 | 2 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Neslin EMEKLİ |
| Name of Lecturer(s) | Assist.Prof. Derya CANSIZ |
| Assistant(s) | |
| Aim | This course; Introduction to Biochemistry -Macromolecules, Carbohydrates, Carbohydrate metabolism, Electron transport chain (ETZ), Proteins, Topic repetition, Enzymes, Protein and amino acid breakdown, Lipids, Digestion and absorption of lipids, Fatty acid oxidation, Catabolism, Vitamins and Minerals, In the Clinical Biochemistry laboratory ; sampling, preanalytical errors and tests, Subject repetition; includes topics. Recognize laboratory measurement methods and laboratory measurement methods, Recognize blood, urine, CSF and stool analysis, Will transfer the analysis of urinary system stones, Explain hormone and mineral analysis, Anticoagulants, Issues to be considered in sample acceptance (lipemia, hemolysis, etc.) Inappropriate sample definition, sample rejection criteria, quality control, |
| Course Content | This course contains; Introduction to biochemistry - Macromolecules,carbohydrates,carbohydrate metabolism,Electron transport chain (ETC),Proteins,enzymes,Protein and amino acid breakdown,lipids,Digestion and absorption of lipids,Fatty acid oxidation,Catabolism,Vitamins and Minerals,Hormones,Sample collection, preanalytical errors and tests in laboratories. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explains the general terms of biochemistry and learns the biochemical events that occur in the cell, Understands the definition of biochemistry and the subjects within the scope of biochemistry, Summarizes the general definition of biochemical molecules and reactions, Comprehends the professional and clinical importance of biochemistry. | 10, 16, 9 | A, E |
| Defines the structure and functions of carbohydrates and comprehends their importance in the human body, Recognizes the general properties of carbohydrates and learns their classification, Understands the chemical properties of carbohydrates, Learns the experiments of recognizing carbohydrates. | 10, 16, 9 | A, E |
| Learns carbohydrate metabolism and understands the relationship of these pathways with each other. Learns carbohydrate digestion and absorption events and carbohydrate metabolism. Understands glycogen metabolism with pathways such as glycogen synthesis and destruction. Learns energy production through electron transport and oxidative phosphorylation. | 10, 16, 9 | A, E |
| Defines the structure and functions of proteins and comprehends their role in metabolism. Learns the properties of amino acids, their chemical reactions. Learns their structures such as peptides and polypeptides. Understands the properties of proteins. | 10, 16, 9 | A, E |
| Learns the structure, functions and general properties of enzymes, Understands the common features of enzymes, Learns the naming and classification of enzymes, Defines the role of enzymes in metabolic pathways. | 10, 16 | A, E |
| Understands the structure of lipids, their role in metabolic pathways and their importance in the human body, Learns the classification of lipids, the structure of fatty acids and their derivatives, Learns the digestion and absorption of lipids, Learns fatty acid metabolism and beta oxidation. | 10, 16, 9 | A, E |
| Learns the functions and importance of vitamins and minerals in metabolic reactions in living organisms, Understands the classification and structures of vitamins, Learns types of minerals, understands their importance for the human body, Understands the role of vitamins and minerals in metabolism. | 10, 16, 9 | A, E |
| Comprehends the functioning of the clinical biochemistry laboratory, has knowledge about sampling and preventing preanalytical errors, Gains knowledge about laboratory organization, rules and safety, Learns the analysis methods used in biochemistry, Understands the variables before sample collection and analysis. | 10, 16, 9 | A, E |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to biochemistry - Macromolecules | Part 1 of the 1st resource - Part 14 of the 2nd resource - Part 1 of the 3rd resource - Part 1,2 of the 4th resource - Part 1 of the 5th resource - Part 1 of the 7th resource |
| 2 | carbohydrates | Chapter 2 of the 2nd resource - Chapter 9 of the 3rd resource - Section 9,15,16 of the 4th resource - Section 2 of the 5th resource - Section 3,6 of the 7th resource |
| 3 | carbohydrate metabolism | Part 14 of reference 2 - Part 9, 15, 16, 20 of reference 4 - Part 2 of reference 5 - Part 3,6 of reference 7 |
| 4 | Electron transport chain (ETC) | Chapter 2 of the 2nd resource - Chapter 9,15,16,20 of the 4th resource - Part 2 of the 5th resource - Section 3,6 of the 7th resource transport chain (ETZ) |
| 5 | Proteins | Chapter 2 of the 2nd resource - Chapter 5,6,7 of the 4th resource - Part 2 of the 5th resource - Chapter 4 of the 7th resource |
| 6 | enzymes | Chapter 2 of Chapter 14 - Chapter 4 of Chapter 8 - Chapter 2 of Source 5 - Chapter 5 of Source 7 |
| 7 | Protein and amino acid breakdown | Chapter 2 of the 2nd resource - Chapter 5,6,7 of the 4th resource - Part 2 of the 5th resource - Chapter 4 of the 7th resource |
| 8 | lipids | Chapter 2 of resource 14 - section 11, 17, 21 of resource 4 - Section 2 of resource 5 - section 7 of resource 7 |
| 9 | Digestion and absorption of lipids | Chapter 2 of resource 14 - section 11, 17, 21 of resource 4 - Section 2 of resource 5 - section 7 of resource 7 |
| 10 | Fatty acid oxidation | Chapter 2 of resource 14 - section 11, 17, 21 of resource 4 - Section 2 of resource 5 - section 7 of resource 7 |
| 11 | Catabolism | Part 14 of the 2nd resource - Part 1,2,3 of the 4th resource - Part 2 of the 5th resource - Part 3 of the 7th resource |
| 12 | Vitamins and Minerals | Chapter 2 of Chapter 14 - Chapter 5 of Source 5 - Chapter 10 of Source 7 |
| 13 | Hormones | Chapter 2 of Chapter 14 - Chapter 4 of Chapter 23 - Chapter 5 of Chapter 4 - Chapter 9 of Source 7 |
| 14 | Sample collection, preanalytical errors and tests in laboratories | 1st resource section 5,6 - 2nd resource section 1,4,13 - 3rd resource section 1,4,20,21,22 |
| Resources |
| 1. Clinical Biochemistry, Prof. Dr. Nesrin RETIRED; Assoc. Dr. Türkan Yiğitbaşı, Medipol University 2nd Biochemistry Laboratory for Students 3rd Edition, Prof. Dr. Nesrin RETIRED; Assoc. Dr. Türkan Yiğitbaşı, Medipol University 3rd Handbook of Clinical Biochemistry (with the addition of Hematology and Serology Laboratories), Author: İdris Mehmetoğlu, Publisher: Nobel Medicine Bookstores 4. Lehninger Biochemistry Ikeleri, Authors: David L. Nelson - Michael M. Cox, Publisher: PALME PUBLISHING, Translation Editor: Y. Murat Elçin, Number of Editions: Translation from the fifth edition 5. Harper Biyokimya, Author(s): Murray, Bender, Weil, Botham, Kennely, Rodwell, Translation Editor: Prof. Dr. Gul Guner Akdogan, Prof.Dr. Biltan Ersoz, Prof. Dr. Nevbahar Turgan 6. Tietz Laboratory Tests Clinical Guide, Author: Alan H. B. WU, Translation Editor: Prof. Dr. Kaya EMERK 7. Human Biochemistry, Brand: Palme Publishing, Author: Prof. Dr. Taner ONAT |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Equipped with adequate, trustworthy and up-to-date knowledge of Physiotherapy and Rehabilitation. | X | |||||
| 2 | PQ-2. It uses the evaluation methods for healthy, disabled and individuals who require physiotherapy and plans and implements the physiotherapy program. | X | |||||
| 3 | PQ-4. Practices using knowledge and skills based on the evidence specific to the field of physiotherapy and rehabilitation. | ||||||
| 4 | PQ-4. For function and independence in the daily life activities of individuals who require physiotherapy and rehabilitation, physiotherapy applications can be carried out using appropriate technology, training and treatment equipment. | ||||||
| 5 | PQ-5. Has the ability to work independently and effectively between disciplinary and interdisciplinary in his professional practices. | X | |||||
| 6 | PQ-6. Social responsibility plays a role in consciousness, research, projects and events. | X | |||||
| 7 | PQ-7. Adopt life-time adaptation to new conditions, learning, developing new ideas, attaching importance to quality, and use information sources effectively. | X | |||||
| 8 | PQ-8. The developments in physiotherapy and rehabilitation are followed by at least one foreign language. | X | |||||
| 9 | PQ-9. Has the ability to communicate verbally and in writing in Turkish. | X | |||||
| 10 | PQ-10. Act in accordance with the legislation and professional codes of conduct in cooperation with the relevant disciplines, considering the rights and responsibilities of the task in physiotherapy and rehabilitation applications. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |