Course Detail
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY and GENETICS | - | Fall Semester | 3+0 | 3 | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Yasemin YOZGAT BYRNE |
| Name of Lecturer(s) | Assist.Prof. Yasemin YOZGAT BYRNE |
| Assistant(s) | |
| Aim | To examine general concepts about the general structure and functions of the cell and hereditary material and to inform about genetic mechanisms. |
| Course Content | This course contains; Introduction to medical biology, Historical approach, General properties of cells,Cell organization (prokaryote-eukaryote comparison), Cell membrane and its properties,Cytoskeleton and Cell organelles,Genetic material structure, function, DNA-RNA, Gene organization and regulation of gene expression,Chromatin, Chromosome, Centromere and Telomere,Cell cycle and DNA replication,Transcription and Translation,Chromosomal structure and number anomalies, mutation and polymorphism,DNA damage and repair mechanisms,Cell aging, Apoptosis and cancer mechanisms,Mendelian Genetics and inheritance models, Non-Mendelian inheritance models,human genome project,molecular biology techniques,Cytogenetics, prenatal diagnosis and genetic counseling. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Defines cell types, organelles, genetic material. | 10, 16, 9 | A |
| Describes functions of organelles and cell membrane and explains cell skeleton. | 10, 16, 9 | A |
| Describes chromosomes, DNA and RNA. | 10, 16, 9 | A |
| Describes organization of genes and regulation of gene expression. | 10, 16, 9 | A |
| Explains the stages of cell cycle and cell divisions and also debates cellular synthesis mechanisms. | 10, 16, 9 | A |
| Describes stages and check points of cell cycle. | 10, 16, 9 | A |
| Explains mitotic and meiotic divisions and associate them with genetic abnormalities and cancer. | 10, 16, 9 | A |
| Describes transcription and regulation. | 10, 16, 9 | A |
| Categorizes chromosomal abnormalities and DNA damage mechanisms and associate them with diseases. | 10, 16, 9 | A |
| Explains DNA mutations and repair mechanisms. | 10, 16, 9 | A |
| Explains cell aging, apoptosis and development of cancer. | 10, 16, 9 | A |
| Defines inheritance models, discusses molecular biology techniques and their areas of use, and interprets genetic diagnosis methods. | 10, 16, 9 | A |
| Describes Mendelian inheritance. | 10, 16, 9 | A |
| Describes non-Mendelian inheritance. | 10, 16, 9 | A |
| Explains human genomne project. | 10, 16, 9 | A |
| Explains molecular biology techniques and associates them with genetic diagnosis. | 10, 16, 9 | A |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to medical biology, Historical approach, General properties of cells | 3rd source part 1 |
| 2 | Cell organization (prokaryote-eukaryote comparison), Cell membrane and its properties | 2nd source page 9-19 and 3rd source part 2 |
| 3 | Cytoskeleton and Cell organelles | 3 sources chapters 4 and 6, 2nd source pages 65 and 165 |
| 4 | Genetic material structure, function, DNA-RNA, Gene organization and regulation of gene expression | 3rd source part 8 and 5th source part 3 |
| 5 | Chromatin, Chromosome, Centromere and Telomere | 2nd source page 176, 5th source page 5 |
| 6 | Cell cycle and DNA replication | 3. source episode 11 |
| 7 | Transcription and Translation | 3rd reference page 174 and 195 |
| 8 | Chromosomal structure and number anomalies, mutation and polymorphism | 5. source parts 2 and 6 |
| 9 | DNA damage and repair mechanisms | 3. source page 162 |
| 10 | Cell aging, Apoptosis and cancer mechanisms | 2nd source page 257, 3rd source pages 309 and 311, 5th source page 311 |
| 11 | Mendelian Genetics and inheritance models, Non-Mendelian inheritance models | 5. source, chapter 5 |
| 12 | human genome project | 5. source page 111 |
| 13 | molecular biology techniques | 5. source part 4 |
| 14 | Cytogenetics, prenatal diagnosis and genetic counseling | 5. source page 135, pages 359 and 375 |
| Resources |
| Lecture Source 1) Lecturer's presentations: The following book chapters -sources 2, 3, 4, and 5 - are used for lecture presentation slides. Lecture Source 2) Tıbbi Biyoloji Ders Kitabı, Cerrahpaşa Tıp Fakültesi Yayın No:275, İstanbul, 2009. Lecture Source 3) Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013. Lecture Source 4) Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Essential Cell Biology, Fourth Edition, Garland Science Publishers, USA, 2013. Mebis Notes Lecture Source 5) Robert L. Nussbaum, Roderick R. Mcinnes, Huntington F. Willard. Thompson and Thompson Tıbbi Genetik, Güneş tıp Kitabevi, 2005. |
| 1)Alberts B, Bray A, Lewis J. Molecular Biology of Cell, Garland Publishing, Inc., New York 1989. 2)David L. Nelson, Michael M. Cox, Lehninger Biyokimyanın İlkeleri, Palme Yayınevi, Ankara, 2013 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. He/she has sufficient knowledge that allows meeting the health needs of person, family and community by individual and holistic approach and toward nursing process. | X | |||||
| 2 | PY-2. He/she has abilities related to carrying out nursing care in order to protect and improve the health and when health is destroyed. | X | |||||
| 3 | PQ-3. He/she has general culture knowledge because of as being required contemporary person and vocation member. | X | |||||
| 4 | PQ-4. He/she conducts the nursing care in accordance with scientific researches, evidence, improving technology and current health policies. | X | |||||
| 5 | PQ-5. He/she carries out nursing practices in accordance with vocational essentials and standards. | X | |||||
| 6 | PQ-6. He/she uses critical thinking, problem solving and decision making abilities in nursing care. | X | |||||
| 7 | PQ-7. He/she give health education to the person, family and community and consultation. | X | |||||
| 8 | PQ-8. He/she follows management activities in accordance with executive role as in individual and team member. | ||||||
| 9 | PQ-9. He/she takes roles in research, project and other activities as in collaboration with health team and other disciplines by consciousness for social responsibilities. | X | |||||
| 10 | PQ-10. He/she reaches international literature by using a foreign language in nursing domain and communicates as written and verbal. | X | |||||
| 11 | PQ-11. He/she improves a behavior that internalizes lifespan learning and open for improvement. | X | |||||
| 12 | PQ-12. He/she communicates as written and verbal, effectively. | X | |||||
| 13 | PQ-13. He/She is a model for colleagues and society by behaving as consonant with vocational essentials and values. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 14 | 3 | 42 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 15 | 15 | |||
| General Exam | 1 | 20 | 20 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 119 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(119/30) | 4 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY and GENETICS | - | Fall Semester | 3+0 | 3 | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Yasemin YOZGAT BYRNE |
| Name of Lecturer(s) | Assist.Prof. Yasemin YOZGAT BYRNE |
| Assistant(s) | |
| Aim | To examine general concepts about the general structure and functions of the cell and hereditary material and to inform about genetic mechanisms. |
| Course Content | This course contains; Introduction to medical biology, Historical approach, General properties of cells,Cell organization (prokaryote-eukaryote comparison), Cell membrane and its properties,Cytoskeleton and Cell organelles,Genetic material structure, function, DNA-RNA, Gene organization and regulation of gene expression,Chromatin, Chromosome, Centromere and Telomere,Cell cycle and DNA replication,Transcription and Translation,Chromosomal structure and number anomalies, mutation and polymorphism,DNA damage and repair mechanisms,Cell aging, Apoptosis and cancer mechanisms,Mendelian Genetics and inheritance models, Non-Mendelian inheritance models,human genome project,molecular biology techniques,Cytogenetics, prenatal diagnosis and genetic counseling. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Defines cell types, organelles, genetic material. | 10, 16, 9 | A |
| Describes functions of organelles and cell membrane and explains cell skeleton. | 10, 16, 9 | A |
| Describes chromosomes, DNA and RNA. | 10, 16, 9 | A |
| Describes organization of genes and regulation of gene expression. | 10, 16, 9 | A |
| Explains the stages of cell cycle and cell divisions and also debates cellular synthesis mechanisms. | 10, 16, 9 | A |
| Describes stages and check points of cell cycle. | 10, 16, 9 | A |
| Explains mitotic and meiotic divisions and associate them with genetic abnormalities and cancer. | 10, 16, 9 | A |
| Describes transcription and regulation. | 10, 16, 9 | A |
| Categorizes chromosomal abnormalities and DNA damage mechanisms and associate them with diseases. | 10, 16, 9 | A |
| Explains DNA mutations and repair mechanisms. | 10, 16, 9 | A |
| Explains cell aging, apoptosis and development of cancer. | 10, 16, 9 | A |
| Defines inheritance models, discusses molecular biology techniques and their areas of use, and interprets genetic diagnosis methods. | 10, 16, 9 | A |
| Describes Mendelian inheritance. | 10, 16, 9 | A |
| Describes non-Mendelian inheritance. | 10, 16, 9 | A |
| Explains human genomne project. | 10, 16, 9 | A |
| Explains molecular biology techniques and associates them with genetic diagnosis. | 10, 16, 9 | A |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to medical biology, Historical approach, General properties of cells | 3rd source part 1 |
| 2 | Cell organization (prokaryote-eukaryote comparison), Cell membrane and its properties | 2nd source page 9-19 and 3rd source part 2 |
| 3 | Cytoskeleton and Cell organelles | 3 sources chapters 4 and 6, 2nd source pages 65 and 165 |
| 4 | Genetic material structure, function, DNA-RNA, Gene organization and regulation of gene expression | 3rd source part 8 and 5th source part 3 |
| 5 | Chromatin, Chromosome, Centromere and Telomere | 2nd source page 176, 5th source page 5 |
| 6 | Cell cycle and DNA replication | 3. source episode 11 |
| 7 | Transcription and Translation | 3rd reference page 174 and 195 |
| 8 | Chromosomal structure and number anomalies, mutation and polymorphism | 5. source parts 2 and 6 |
| 9 | DNA damage and repair mechanisms | 3. source page 162 |
| 10 | Cell aging, Apoptosis and cancer mechanisms | 2nd source page 257, 3rd source pages 309 and 311, 5th source page 311 |
| 11 | Mendelian Genetics and inheritance models, Non-Mendelian inheritance models | 5. source, chapter 5 |
| 12 | human genome project | 5. source page 111 |
| 13 | molecular biology techniques | 5. source part 4 |
| 14 | Cytogenetics, prenatal diagnosis and genetic counseling | 5. source page 135, pages 359 and 375 |
| Resources |
| Lecture Source 1) Lecturer's presentations: The following book chapters -sources 2, 3, 4, and 5 - are used for lecture presentation slides. Lecture Source 2) Tıbbi Biyoloji Ders Kitabı, Cerrahpaşa Tıp Fakültesi Yayın No:275, İstanbul, 2009. Lecture Source 3) Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013. Lecture Source 4) Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Essential Cell Biology, Fourth Edition, Garland Science Publishers, USA, 2013. Mebis Notes Lecture Source 5) Robert L. Nussbaum, Roderick R. Mcinnes, Huntington F. Willard. Thompson and Thompson Tıbbi Genetik, Güneş tıp Kitabevi, 2005. |
| 1)Alberts B, Bray A, Lewis J. Molecular Biology of Cell, Garland Publishing, Inc., New York 1989. 2)David L. Nelson, Michael M. Cox, Lehninger Biyokimyanın İlkeleri, Palme Yayınevi, Ankara, 2013 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. He/she has sufficient knowledge that allows meeting the health needs of person, family and community by individual and holistic approach and toward nursing process. | X | |||||
| 2 | PY-2. He/she has abilities related to carrying out nursing care in order to protect and improve the health and when health is destroyed. | X | |||||
| 3 | PQ-3. He/she has general culture knowledge because of as being required contemporary person and vocation member. | X | |||||
| 4 | PQ-4. He/she conducts the nursing care in accordance with scientific researches, evidence, improving technology and current health policies. | X | |||||
| 5 | PQ-5. He/she carries out nursing practices in accordance with vocational essentials and standards. | X | |||||
| 6 | PQ-6. He/she uses critical thinking, problem solving and decision making abilities in nursing care. | X | |||||
| 7 | PQ-7. He/she give health education to the person, family and community and consultation. | X | |||||
| 8 | PQ-8. He/she follows management activities in accordance with executive role as in individual and team member. | ||||||
| 9 | PQ-9. He/she takes roles in research, project and other activities as in collaboration with health team and other disciplines by consciousness for social responsibilities. | X | |||||
| 10 | PQ-10. He/she reaches international literature by using a foreign language in nursing domain and communicates as written and verbal. | X | |||||
| 11 | PQ-11. He/she improves a behavior that internalizes lifespan learning and open for improvement. | X | |||||
| 12 | PQ-12. He/she communicates as written and verbal, effectively. | X | |||||
| 13 | PQ-13. He/She is a model for colleagues and society by behaving as consonant with vocational essentials and values. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |