It is aimed to strengthen the basic biochemistry knowledge of 2 nd year students in this course, which is going to be taken in Spring. We will start the course by focusing on the structure and properties of water which is one of the important molecules that form organisms. The acid/base character of amino acids along with the structure, function, and purification methods of proteins will also be studied. This will be followed by considering the structure and function of enzyme as well as their regulation. Subsequently, the mechanism of a enzyme-ligand complex will be focused on the basis of allostery and cooperatively phenomena. Finally, some selected hot topics in the field of biochemistry will be discussed interactively with the students.
Course Content
This course contains; Molecular Interactions in a Biological Context Introduction to Biochemistry ,Overview of Energy and Metabolism,Carbohydrates,Glycogen Metabolism ,Glycolysis,Citric Acid Cycle ,Electron Transfer Chain and Oxidative Phosphorylation ,Enzyme Reactions,Lipids,Lipid Metabolism,Amino Acids,Protein Structure,Fibrous Proteins,Globular Proteins.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
1) Equipped with basic knowledge of biochemistry; understanding biochemistry-related problems easily.
12, 14, 16, 17, 9
2) Capable of evaluating basic knowledge via books and related means.
12, 14, 16, 9
3) Recognize and differentiate protein, carbohydrate and lipid molecules along with their physical and chemical properties.
12, 14, 16, 17, 9
4) Capable of commenting on the ionization states of aminoacids under a given condition by means of knowledge on the acid/base properties of these biological building blocks.
12, 14, 16, 17, 9
5) Capable of testing biochemistry concepts by means of experiments.
14, 16, 17, 9
6) Capable of commenting on the possible role of an enzyme by means of the knowledge pertaining to structure, function and regulation of these molecules.
12, 14, 17, 9
7) Capable of analyzing the factors and their relative contribution on a given reaction.
12, 14, 16, 17, 9
8) Capable of understanding the etiology of some diseases that are caused by problems occur in the metabolism of biological molecules.
12, 14, 16, 17, 9
9) Capable of analyzing some biochemistry related hot topics
12, 14, 9
10) Capable of analyzing, organizing, discussing results of experiments and expressing them by his/her own.
12, 14, 17, 9
11) Capable of using computer technology for solving and analyzing problems.
12, 14, 9
Teaching Methods:
12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method
Assessment Methods:
Course Outline
Order
Subjects
Preliminary Work
1
Molecular Interactions in a Biological Context Introduction to Biochemistry
2
Overview of Energy and Metabolism
3
Carbohydrates
4
Glycogen Metabolism
5
Glycolysis
6
Citric Acid Cycle
7
Electron Transfer Chain and Oxidative Phosphorylation
8
Enzyme Reactions
9
Lipids
10
Lipid Metabolism
11
Amino Acids
12
Protein Structure
13
Fibrous Proteins
14
Globular Proteins
Resources
Principles of Biochemistry - 5 th edition - Laurence A. Moran & Robert A. Horton 2.
Biochemistry - 8 th edition- Mary K. Campbell & Shawn O. Farrell.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
10
A knowledge of contemporary issues
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
12
Capability to apply and decide on engineering principals while understanding and rehabilitating the human body
X
Assessment Methods
Contribution Level
Absolute Evaluation
Rate of Midterm Exam to Success
30
Rate of Final Exam to Success
70
Total
100
ECTS / Workload Table
Activities
Number of
Duration(Hour)
Total Workload(Hour)
Course Hours
14
3
42
Guided Problem Solving
14
8
112
Resolution of Homework Problems and Submission as a Report
4
3
12
Term Project
0
0
0
Presentation of Project / Seminar
0
0
0
Quiz
4
1
4
Midterm Exam
2
17
34
General Exam
1
32
32
Performance Task, Maintenance Plan
0
0
0
Total Workload(Hour)
236
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(236/30)
8
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.
Detail Informations of the Course
Course Description
Course
Code
Semester
T+P (Hour)
Credit
ECTS
BIOCHEMISTRY
-
Spring Semester
3+2
4
8
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of Course
English
Course Level
First Cycle (Bachelor's Degree)
Course Type
Required
Course Coordinator
Assoc.Prof. Sultan Sibel ERDEM
Name of Lecturer(s)
Assoc.Prof. Sultan Sibel ERDEM
Assistant(s)
Aim
It is aimed to strengthen the basic biochemistry knowledge of 2 nd year students in this course, which is going to be taken in Spring. We will start the course by focusing on the structure and properties of water which is one of the important molecules that form organisms. The acid/base character of amino acids along with the structure, function, and purification methods of proteins will also be studied. This will be followed by considering the structure and function of enzyme as well as their regulation. Subsequently, the mechanism of a enzyme-ligand complex will be focused on the basis of allostery and cooperatively phenomena. Finally, some selected hot topics in the field of biochemistry will be discussed interactively with the students.
Course Content
This course contains; Molecular Interactions in a Biological Context Introduction to Biochemistry ,Overview of Energy and Metabolism,Carbohydrates,Glycogen Metabolism ,Glycolysis,Citric Acid Cycle ,Electron Transfer Chain and Oxidative Phosphorylation ,Enzyme Reactions,Lipids,Lipid Metabolism,Amino Acids,Protein Structure,Fibrous Proteins,Globular Proteins.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
1) Equipped with basic knowledge of biochemistry; understanding biochemistry-related problems easily.
12, 14, 16, 17, 9
2) Capable of evaluating basic knowledge via books and related means.
12, 14, 16, 9
3) Recognize and differentiate protein, carbohydrate and lipid molecules along with their physical and chemical properties.
12, 14, 16, 17, 9
4) Capable of commenting on the ionization states of aminoacids under a given condition by means of knowledge on the acid/base properties of these biological building blocks.
12, 14, 16, 17, 9
5) Capable of testing biochemistry concepts by means of experiments.
14, 16, 17, 9
6) Capable of commenting on the possible role of an enzyme by means of the knowledge pertaining to structure, function and regulation of these molecules.
12, 14, 17, 9
7) Capable of analyzing the factors and their relative contribution on a given reaction.
12, 14, 16, 17, 9
8) Capable of understanding the etiology of some diseases that are caused by problems occur in the metabolism of biological molecules.
12, 14, 16, 17, 9
9) Capable of analyzing some biochemistry related hot topics
12, 14, 9
10) Capable of analyzing, organizing, discussing results of experiments and expressing them by his/her own.
12, 14, 17, 9
11) Capable of using computer technology for solving and analyzing problems.
12, 14, 9
Teaching Methods:
12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 9: Lecture Method
Assessment Methods:
Course Outline
Order
Subjects
Preliminary Work
1
Molecular Interactions in a Biological Context Introduction to Biochemistry
2
Overview of Energy and Metabolism
3
Carbohydrates
4
Glycogen Metabolism
5
Glycolysis
6
Citric Acid Cycle
7
Electron Transfer Chain and Oxidative Phosphorylation
8
Enzyme Reactions
9
Lipids
10
Lipid Metabolism
11
Amino Acids
12
Protein Structure
13
Fibrous Proteins
14
Globular Proteins
Resources
Principles of Biochemistry - 5 th edition - Laurence A. Moran & Robert A. Horton 2.
Biochemistry - 8 th edition- Mary K. Campbell & Shawn O. Farrell.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
10
A knowledge of contemporary issues
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
12
Capability to apply and decide on engineering principals while understanding and rehabilitating the human body