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Course Description

CourseCodeSemesterT+P (Hour)CreditECTS
BIOCHEMISTRY-Yearly76+8-6
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of CourseTurkish
Course LevelFirst Cycle (Bachelor's Degree)
Course TypeCommittee Course
Course CoordinatorProf.Dr. Türkan YİĞİTBAŞI
Name of Lecturer(s)Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assist.Prof. Çağrı ÇAKICI, Assist.Prof. Derya CANSIZ
Assistant(s)
AimDefining all of the chemical reactions on the molecular level within the cell and explaining the changes in these reactions under pathological conditions.
Course ContentThis course contains; Moleculer fundamental of life ,Carbohydrate metabolism,Energy storage:Glycogen synthesis and catabolism,Glucuronic acid pathway,Energy production I : Glycolysis,Energy production II: Citric acid cycle ,Pendose phosphate pathway ,Glukoneogenez ,Metabolic control of glucose,Spectrophotometer,Blood glucose assay ,Lipids,Triglycerides, phospholipids and eicosanoids,Cholesterol, Steroids and Isoprenes,Lipoproteins,Fatty acid synthesis,Beta oxidation,Oxidative phosphorylation ,Lipid analysis,Membrane and Transport,Biologic oxidation and antioxidants
,Amino acids and transport ,Biosynthesis and catabolism of amino acids,Aminoacid Introducing Reactions ,Urea synthesis ,Biologic amines ,Enyzmes I ,Enyzmes II,Structure of vitamins ,Mechanism action of vitamins ,Inorganic molecules I,Inorganic molecules II ,Signal Transmission,Structure of hormones,Hormone action metabolism
,Structure and function of proteins,Clasifications of proteins In MEBIS, the student was informed about the subject.,Hemoglobin and Collagen ,Protein analysis in blood
,Nucleic acids,Buffer systems,Body fluids ,Water metabolism.
Dersin Öğrenme KazanımlarıTeaching MethodsAssessment Methods
1- Explain structure and funcution of macromelcules(carbohydrates, proteins, lipids and nucleic acids), and understands the relationship between these molecules in human cells.16, 17, 19, 9A, D, E, G
1.1.Explain the definition and general properties of monosaccharides, disaccharides and polysaccharides.16, 17, 19, 9A, D, E, G
1.2.Explain the structure and general properties of lipids and fatty acids, lipoproteins, sphingolipids, steroids.16, 17, 18, 19, 9A, D, E, G
1.3.Explains amino acids and their properties, structure of proteins, classification of proteins.16, 17, 19, 9A, D, E, G
1.4.Defines hormones and their structure, and the mechanism of action of hormones.16, 17, 19, 9A, D, E, G
1.5.Explaines the structure and general properties of vitamins and minerals.16, 17, 19, 9A, D, E, G
2- Explain the structural and functional importance of macromolecules in the human body and discuss their relationship with diseases.17, 19, 9A, D, E, G
2.1.Explains the diseases caused by enzyme deficiencies in metabolic pathways.16, 17, 19, 9A, D, E, G
2.2.Explains enzyme deficiencies in urea synthesis.16, 17, 19, 9A, D, E, G
2.3.Defines lipid and glycogen storage diseases.16, 17, 19, 9A, D, E, G
2.4.Explains the metabolic control of glucose and glucose metabolism disorders and related metabolic disorders such as atherosclerosis.16, 17, 19, 9A, D, E, G
3.Explains anabolic and catabolic pathways related to obtaining energy from macromolecules and the control steps in these pathways.16, 17, 19, 9A, D, E, G
3.1.Explains bioenergy, glycogen production and degradation, glycolysis, gluconeogenesis, citric acid cycle, pentose phosphate pathway, oxidative phosphorylation.16, 17, 19, 9A, D, E, G
3.2.Defines issues related to fat metabolism such as oxidation of fatty acids, ketogenesis and lipogenesis.16, 17, 19, 9A, D, E, G
3.3. Explains the intersection points between all metabolic pathways and explains energy metabolism16, 17, 19, 9A, D, E, G
3.4. Explains the metabolic control mechanisms of macromolecules, the effects and relationships of enzymes and hormones in these control steps. Explains signal transmission systems.16, 17, 19, 9A, D, E, G
3.5. Explains the relationship between energy metabolism and nutrition.16, 17, 19, 9A, D, E, G
4. Explain the importance of issues related to body homeostasis.16, 17, 19, 9A, D, E
4.1. Explains the relationship between buffer systems and blood pH16, 17, 19, 9A, D, E, G
4.2. Explains the physical, chemical and microscopic properties of urine.16, 17, 19, 9A, D, E, G
4.3. Explains the relationship between urine and kidney functions.16, 17, 19, 9A, D, E, G
4.4. Explains the importance of water in metabolism.16, 17, 19, 9A, D, E, G
Teaching Methods:16: Question - Answer Technique, 17: Experimental Technique, 18: Micro Teaching Technique, 19: Brainstorming Technique, 9: Lecture Method
Assessment Methods:A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz

Course Outline

OrderSubjectsPreliminary Work
1Moleculer fundamental of life In MEBIS, the student was informed about the subject.
2Carbohydrate metabolismIn MEBIS, the student was informed about the subject.
3Energy storage:Glycogen synthesis and catabolismIn MEBIS, the student was informed about the subject.
4Glucuronic acid pathwayIn MEBIS, the student was informed about the subject.
5Energy production I : GlycolysisIn MEBIS, the student was informed about the subject.
6Energy production II: Citric acid cycle In MEBIS, the student was informed about the subject.
7Pendose phosphate pathway In MEBIS, the student was informed about the subject.
8Glukoneogenez In MEBIS, the student was informed about the subject.
9Metabolic control of glucoseIn MEBIS, the student was informed about the subject.
10SpectrophotometerIn MEBIS, the student was informed about the subject.
11Blood glucose assay In MEBIS, the student was informed about the subject.
12LipidsIn MEBIS, the student was informed about the subject.
13Triglycerides, phospholipids and eicosanoidsIn MEBIS, the student was informed about the subject.
14Cholesterol, Steroids and IsoprenesIn MEBIS, the student was informed about the subject.
15LipoproteinsIn MEBIS, the student was informed about the subject.
16Fatty acid synthesisIn MEBIS, the student was informed about the subject
17Beta oxidationIn MEBIS, the student was informed about the subject
18Oxidative phosphorylation In MEBIS, the student was informed about the subject
19Lipid analysisIn MEBIS, the student was informed about the subject
20Membrane and TransportIn MEBIS, the student was informed about the subject
21Biologic oxidation and antioxidants
In MEBIS, the student was informed about the subject
22Amino acids and transport In MEBIS, the student was informed about the subject
23Biosynthesis and catabolism of amino acidsIn MEBIS, the student was informed about the subject.
24Aminoacid Introducing Reactions In MEBIS, the student was informed about the subject.
25Urea synthesis In MEBIS, the student was informed about the subject.
26Biologic amines In MEBIS, the student was informed about the subject.
27Enyzmes I In MEBIS, the student was informed about the subject.
28Enyzmes IIIn MEBIS, the student was informed about the subject.
29Structure of vitamins In MEBIS, the student was informed about the subject.
30Mechanism action of vitamins In MEBIS, the student was informed about the subject.
31Inorganic molecules IIn MEBIS, the student was informed about the subject.
32Inorganic molecules II In MEBIS, the student was informed about the subject.
33Signal TransmissionIn MEBIS, the student was informed about the subject.
34Structure of hormonesIn MEBIS, the student was informed about the subject.
35Hormone action metabolism
In MEBIS, the student was informed about the subject.
36Structure and function of proteinsIn MEBIS, the student was informed about the subject.
37Clasifications of proteins In MEBIS, the student was informed about the subject.In MEBIS, the student was informed about the subject.
38Hemoglobin and Collagen In MEBIS, the student was informed about the subject.
39Protein analysis in blood
In MEBIS, the student was informed about the subject.
40Nucleic acidsIn MEBIS, the student was informed about the subject.
41Buffer systemsIn MEBIS, the student was informed about the subject.
42Body fluids In MEBIS, the student was informed about the subject.
43Water metabolismIn MEBIS, the student was informed about the subject.
Resources
Basic and Applied Biochemistry (Nesrin Emekli),Biokimya (Fügen Gürdöl ve Evin Ademoğlu) Biyokimya laboratuvarı(Türkan Yiğitbaşı,Nesrin Emekli).
Harper Biochemistr,Leninger Principles of Biochemistry, Henry's Clinical Diagnosis and Management by Laboratory Methods.

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
NoProgram QualificationContribution Level
12345
1
PQ-1. He/She has the ability to monitor and evaluate the practical tools used in the field of dentistry, the literature containing the most up-to-date information and other resources.
2
PQ-2. He/She has the knowledge to evaluate the source, accuracy, reliability and validity of the information obtained in the field of dentistry. He/she integrates this information with the information of all disciplines in the field of health, analyzes it and uses it in his/her professional practices.
3
PQ-3. He/She interprets and evaluates scientifically proven data, identifies and analyzes problems, develops solution suggestions and provides the most ideal treatment for patients by using the advanced theoretical and practical knowledge acquired in the field of dentistry.
4
PQ-4. He/She provides health education for individuals, families and society by integrating its knowledge in the field of dentistry with the knowledge of other health disciplines, creating interpretations and new information.
5
PQ-5. He/She clearly conveys her thoughts, problems and solution methods, and produces solutions to problems in line with scientific data and evidence by using the advanced theoretical and practical knowledge he/she has acquired in the field of dentistry.
6
PQ-6. He/She independently carries out a study related to the field of dentistry using her advanced knowledge
7
PQ-7. He/She takes responsibility as a team member or individually to solve complex and unpredictable problems encountered in dental applications.
8
PQ-8. He/She assumes the leadership role in solving problems in the field of dentistry, plans and manages activities for the development of employees under its responsibility and examines and evaluates the process.
9
PQ-9 He/She determines the learning needs and goals in the field of dentistry and directs its learning by accessing resources effectively and quickly. He/She is open to development, develops a positive attitude towards lifelong learning and continues this behavior throughout her professional life.
10
PQ-10. He/She informs relevant people and institutions on issues related to the field of dentistry, listens to their thoughts, wishes and expectations, and conveys his/her own thoughts and solution suggestions to problems to experts and non-experts by supporting them with quantitative and qualitative data.
11
PQ-11. He/she examines and improves his/her knowledge in the field of dentistry with his/her colleagues, patients and relatives, with a critical perspective specific to each individual.
12
PQ-12. He/She knows a foreign language (English) at a level that allows him/her to continue his/her professional development by following international publications and meetings in the field of dentistry and to communicate verbally and in writing with his/her colleagues.
13
PQ-13. He/She uses information and communication technologies along with knowledge of computer software and hardware at the level required by the field of dentistry.
14
PQ-14. While practicing dentistry, he/she respects social, scientific, cultural and ethical values in the collection, interpretation, application and announcement of patient data and teaches these values.
15
PQ-15.He/She develops and implements strategies, policies and implementation plans on matters related to dentistry and evaluates the results within the framework of quality processes.
16
PQ-16. He/She uses the knowledge she has absorbed in the field of dentistry in interdisciplinary studies to solve oral and dental health problems of the individual and community.

Assessment Methods

Contribution LevelAbsolute Evaluation
Rate of Midterm Exam to Success 40
Rate of Final Exam to Success 60
Total 100
ECTS / Workload Table
ActivitiesNumber ofDuration(Hour)Total Workload(Hour)
Course Hours000
Guided Problem Solving000
Resolution of Homework Problems and Submission as a Report000
Term Project000
Presentation of Project / Seminar000
Quiz000
Midterm Exam000
General Exam000
Performance Task, Maintenance Plan000
Total Workload(Hour)0
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(0/30)0
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course

Course Description

CourseCodeSemesterT+P (Hour)CreditECTS
BIOCHEMISTRY-Yearly76+8-6
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of CourseTurkish
Course LevelFirst Cycle (Bachelor's Degree)
Course TypeCommittee Course
Course CoordinatorProf.Dr. Türkan YİĞİTBAŞI
Name of Lecturer(s)Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assist.Prof. Çağrı ÇAKICI, Assist.Prof. Derya CANSIZ
Assistant(s)
AimDefining all of the chemical reactions on the molecular level within the cell and explaining the changes in these reactions under pathological conditions.
Course ContentThis course contains; Moleculer fundamental of life ,Carbohydrate metabolism,Energy storage:Glycogen synthesis and catabolism,Glucuronic acid pathway,Energy production I : Glycolysis,Energy production II: Citric acid cycle ,Pendose phosphate pathway ,Glukoneogenez ,Metabolic control of glucose,Spectrophotometer,Blood glucose assay ,Lipids,Triglycerides, phospholipids and eicosanoids,Cholesterol, Steroids and Isoprenes,Lipoproteins,Fatty acid synthesis,Beta oxidation,Oxidative phosphorylation ,Lipid analysis,Membrane and Transport,Biologic oxidation and antioxidants
,Amino acids and transport ,Biosynthesis and catabolism of amino acids,Aminoacid Introducing Reactions ,Urea synthesis ,Biologic amines ,Enyzmes I ,Enyzmes II,Structure of vitamins ,Mechanism action of vitamins ,Inorganic molecules I,Inorganic molecules II ,Signal Transmission,Structure of hormones,Hormone action metabolism
,Structure and function of proteins,Clasifications of proteins In MEBIS, the student was informed about the subject.,Hemoglobin and Collagen ,Protein analysis in blood
,Nucleic acids,Buffer systems,Body fluids ,Water metabolism.
Dersin Öğrenme KazanımlarıTeaching MethodsAssessment Methods
1- Explain structure and funcution of macromelcules(carbohydrates, proteins, lipids and nucleic acids), and understands the relationship between these molecules in human cells.16, 17, 19, 9A, D, E, G
1.1.Explain the definition and general properties of monosaccharides, disaccharides and polysaccharides.16, 17, 19, 9A, D, E, G
1.2.Explain the structure and general properties of lipids and fatty acids, lipoproteins, sphingolipids, steroids.16, 17, 18, 19, 9A, D, E, G
1.3.Explains amino acids and their properties, structure of proteins, classification of proteins.16, 17, 19, 9A, D, E, G
1.4.Defines hormones and their structure, and the mechanism of action of hormones.16, 17, 19, 9A, D, E, G
1.5.Explaines the structure and general properties of vitamins and minerals.16, 17, 19, 9A, D, E, G
2- Explain the structural and functional importance of macromolecules in the human body and discuss their relationship with diseases.17, 19, 9A, D, E, G
2.1.Explains the diseases caused by enzyme deficiencies in metabolic pathways.16, 17, 19, 9A, D, E, G
2.2.Explains enzyme deficiencies in urea synthesis.16, 17, 19, 9A, D, E, G
2.3.Defines lipid and glycogen storage diseases.16, 17, 19, 9A, D, E, G
2.4.Explains the metabolic control of glucose and glucose metabolism disorders and related metabolic disorders such as atherosclerosis.16, 17, 19, 9A, D, E, G
3.Explains anabolic and catabolic pathways related to obtaining energy from macromolecules and the control steps in these pathways.16, 17, 19, 9A, D, E, G
3.1.Explains bioenergy, glycogen production and degradation, glycolysis, gluconeogenesis, citric acid cycle, pentose phosphate pathway, oxidative phosphorylation.16, 17, 19, 9A, D, E, G
3.2.Defines issues related to fat metabolism such as oxidation of fatty acids, ketogenesis and lipogenesis.16, 17, 19, 9A, D, E, G
3.3. Explains the intersection points between all metabolic pathways and explains energy metabolism16, 17, 19, 9A, D, E, G
3.4. Explains the metabolic control mechanisms of macromolecules, the effects and relationships of enzymes and hormones in these control steps. Explains signal transmission systems.16, 17, 19, 9A, D, E, G
3.5. Explains the relationship between energy metabolism and nutrition.16, 17, 19, 9A, D, E, G
4. Explain the importance of issues related to body homeostasis.16, 17, 19, 9A, D, E
4.1. Explains the relationship between buffer systems and blood pH16, 17, 19, 9A, D, E, G
4.2. Explains the physical, chemical and microscopic properties of urine.16, 17, 19, 9A, D, E, G
4.3. Explains the relationship between urine and kidney functions.16, 17, 19, 9A, D, E, G
4.4. Explains the importance of water in metabolism.16, 17, 19, 9A, D, E, G
Teaching Methods:16: Question - Answer Technique, 17: Experimental Technique, 18: Micro Teaching Technique, 19: Brainstorming Technique, 9: Lecture Method
Assessment Methods:A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz

Course Outline

OrderSubjectsPreliminary Work
1Moleculer fundamental of life In MEBIS, the student was informed about the subject.
2Carbohydrate metabolismIn MEBIS, the student was informed about the subject.
3Energy storage:Glycogen synthesis and catabolismIn MEBIS, the student was informed about the subject.
4Glucuronic acid pathwayIn MEBIS, the student was informed about the subject.
5Energy production I : GlycolysisIn MEBIS, the student was informed about the subject.
6Energy production II: Citric acid cycle In MEBIS, the student was informed about the subject.
7Pendose phosphate pathway In MEBIS, the student was informed about the subject.
8Glukoneogenez In MEBIS, the student was informed about the subject.
9Metabolic control of glucoseIn MEBIS, the student was informed about the subject.
10SpectrophotometerIn MEBIS, the student was informed about the subject.
11Blood glucose assay In MEBIS, the student was informed about the subject.
12LipidsIn MEBIS, the student was informed about the subject.
13Triglycerides, phospholipids and eicosanoidsIn MEBIS, the student was informed about the subject.
14Cholesterol, Steroids and IsoprenesIn MEBIS, the student was informed about the subject.
15LipoproteinsIn MEBIS, the student was informed about the subject.
16Fatty acid synthesisIn MEBIS, the student was informed about the subject
17Beta oxidationIn MEBIS, the student was informed about the subject
18Oxidative phosphorylation In MEBIS, the student was informed about the subject
19Lipid analysisIn MEBIS, the student was informed about the subject
20Membrane and TransportIn MEBIS, the student was informed about the subject
21Biologic oxidation and antioxidants
In MEBIS, the student was informed about the subject
22Amino acids and transport In MEBIS, the student was informed about the subject
23Biosynthesis and catabolism of amino acidsIn MEBIS, the student was informed about the subject.
24Aminoacid Introducing Reactions In MEBIS, the student was informed about the subject.
25Urea synthesis In MEBIS, the student was informed about the subject.
26Biologic amines In MEBIS, the student was informed about the subject.
27Enyzmes I In MEBIS, the student was informed about the subject.
28Enyzmes IIIn MEBIS, the student was informed about the subject.
29Structure of vitamins In MEBIS, the student was informed about the subject.
30Mechanism action of vitamins In MEBIS, the student was informed about the subject.
31Inorganic molecules IIn MEBIS, the student was informed about the subject.
32Inorganic molecules II In MEBIS, the student was informed about the subject.
33Signal TransmissionIn MEBIS, the student was informed about the subject.
34Structure of hormonesIn MEBIS, the student was informed about the subject.
35Hormone action metabolism
In MEBIS, the student was informed about the subject.
36Structure and function of proteinsIn MEBIS, the student was informed about the subject.
37Clasifications of proteins In MEBIS, the student was informed about the subject.In MEBIS, the student was informed about the subject.
38Hemoglobin and Collagen In MEBIS, the student was informed about the subject.
39Protein analysis in blood
In MEBIS, the student was informed about the subject.
40Nucleic acidsIn MEBIS, the student was informed about the subject.
41Buffer systemsIn MEBIS, the student was informed about the subject.
42Body fluids In MEBIS, the student was informed about the subject.
43Water metabolismIn MEBIS, the student was informed about the subject.
Resources
Basic and Applied Biochemistry (Nesrin Emekli),Biokimya (Fügen Gürdöl ve Evin Ademoğlu) Biyokimya laboratuvarı(Türkan Yiğitbaşı,Nesrin Emekli).
Harper Biochemistr,Leninger Principles of Biochemistry, Henry's Clinical Diagnosis and Management by Laboratory Methods.

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
NoProgram QualificationContribution Level
12345
1
PQ-1. He/She has the ability to monitor and evaluate the practical tools used in the field of dentistry, the literature containing the most up-to-date information and other resources.
2
PQ-2. He/She has the knowledge to evaluate the source, accuracy, reliability and validity of the information obtained in the field of dentistry. He/she integrates this information with the information of all disciplines in the field of health, analyzes it and uses it in his/her professional practices.
3
PQ-3. He/She interprets and evaluates scientifically proven data, identifies and analyzes problems, develops solution suggestions and provides the most ideal treatment for patients by using the advanced theoretical and practical knowledge acquired in the field of dentistry.
4
PQ-4. He/She provides health education for individuals, families and society by integrating its knowledge in the field of dentistry with the knowledge of other health disciplines, creating interpretations and new information.
5
PQ-5. He/She clearly conveys her thoughts, problems and solution methods, and produces solutions to problems in line with scientific data and evidence by using the advanced theoretical and practical knowledge he/she has acquired in the field of dentistry.
6
PQ-6. He/She independently carries out a study related to the field of dentistry using her advanced knowledge
7
PQ-7. He/She takes responsibility as a team member or individually to solve complex and unpredictable problems encountered in dental applications.
8
PQ-8. He/She assumes the leadership role in solving problems in the field of dentistry, plans and manages activities for the development of employees under its responsibility and examines and evaluates the process.
9
PQ-9 He/She determines the learning needs and goals in the field of dentistry and directs its learning by accessing resources effectively and quickly. He/She is open to development, develops a positive attitude towards lifelong learning and continues this behavior throughout her professional life.
10
PQ-10. He/She informs relevant people and institutions on issues related to the field of dentistry, listens to their thoughts, wishes and expectations, and conveys his/her own thoughts and solution suggestions to problems to experts and non-experts by supporting them with quantitative and qualitative data.
11
PQ-11. He/she examines and improves his/her knowledge in the field of dentistry with his/her colleagues, patients and relatives, with a critical perspective specific to each individual.
12
PQ-12. He/She knows a foreign language (English) at a level that allows him/her to continue his/her professional development by following international publications and meetings in the field of dentistry and to communicate verbally and in writing with his/her colleagues.
13
PQ-13. He/She uses information and communication technologies along with knowledge of computer software and hardware at the level required by the field of dentistry.
14
PQ-14. While practicing dentistry, he/she respects social, scientific, cultural and ethical values in the collection, interpretation, application and announcement of patient data and teaches these values.
15
PQ-15.He/She develops and implements strategies, policies and implementation plans on matters related to dentistry and evaluates the results within the framework of quality processes.
16
PQ-16. He/She uses the knowledge she has absorbed in the field of dentistry in interdisciplinary studies to solve oral and dental health problems of the individual and community.

Assessment Methods

Contribution LevelAbsolute Evaluation
Rate of Midterm Exam to Success 40
Rate of Final Exam to Success 60
Total 100

Numerical Data

Student Success

Ekleme Tarihi: 31/10/2022 - 14:11Son Güncelleme Tarihi: 02/11/2023 - 16:48