Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| EXPERIMENTAL ANIMAL MODELS | - | Spring Semester | 2+4 | 4 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Bircan KOLBAŞI |
| Name of Lecturer(s) | Prof.Dr. İlknur KESKİN, Assist.Prof. Bircan KOLBAŞI |
| Assistant(s) | |
| Aim | The aim of the course is to teach how to induce various disease models in mice and rats, to construct experimental disease models in animals and to apply treatment methods in line with the acquired knowledge. |
| Course Content | This course contains; Creating a DM model with streptozocin,Establishing a liver failure model with CCl4,Creation of ischemia-reperfusion models,Establishment of experimental sepsis or adhesion models,Creation of intraabdominal sepsis models,Establishment of experimental shock models,Midterm,Resection – anastomosis – creation of burst pressure models,Creation of transplantation models,Establishment of experimental models of obstructive jaundice,Creation of experimental pancreatitis models,Establishment of experimental cholangitis models,Creation of peritoneal adhesion models,Final exam. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explain the design of the experimental model of liver failure with CCl4. | 14, 9 | A, E |
| Explains how to create an experimental model with streptozocin. | 14, 9 | A, E |
| Explains ischemia-reperfusion model creation. | 14, 9 | A, E |
| Explains how to create an experimental sepsis or adhesion model. | 14, 9 | A, E |
| Explains how to create intraabdominal sepsis models. | 14, 9 | A, E |
| Explain experimental shock models. | 14, 9 | A, E |
| Explains resection – anastomosis – burst pressure models. | 14, 9 | A, E |
| Explains the transplantation models. | 14, 9 | A, E |
| Explain experimental models of obstructive jaundice. | 14, 9 | A, E |
| Explains experimental models of pancreatitis. | 14, 9 | A, E |
| Explains how to create experimental cholangitis models. | 14, 9 | A, E |
| Explains creating peritoneal adhesion models. | 14, 9 | A, E |
| Teaching Methods: | 14: Self Study Method, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Creating a DM model with streptozocin | Reading the relevant course presentation |
| 2 | Establishing a liver failure model with CCl4 | Reading the relevant course presentation |
| 3 | Creation of ischemia-reperfusion models | Reading the relevant course presentation |
| 4 | Establishment of experimental sepsis or adhesion models | Reading the relevant course presentation |
| 5 | Creation of intraabdominal sepsis models | Reading the relevant course presentation |
| 6 | Establishment of experimental shock models | Reading the relevant course presentation |
| 7 | Midterm | |
| 8 | Resection – anastomosis – creation of burst pressure models | Reading the relevant course presentation |
| 9 | Creation of transplantation models | Reading the relevant course presentation |
| 10 | Establishment of experimental models of obstructive jaundice | Reading the relevant course presentation |
| 11 | Creation of experimental pancreatitis models | Reading the relevant course presentation |
| 12 | Establishment of experimental cholangitis models | Reading the relevant course presentation |
| 13 | Creation of peritoneal adhesion models | Reading the relevant course presentation |
| 14 | Final exam |
| Resources |
| PROF.DR.HASAN BESIM, DENEYSEL HAYVAN MODELLERI, Current literature, Lecture notes |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Develops and deepens current and advanced knowledge in the field of histology with original thought and research at the level of expertise and reaches original definitions that will bring innovation to the field. | X | |||||
| 2 | Defines cell and tissue at an advanced level (ultrastructural). | ||||||
| 3 | Knows the embryological details about the development of systems at an advanced level. | ||||||
| 4 | Comprehends the interdisciplinary interaction that the field is related to; reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | X | |||||
| 5 | Develops a new idea, method, design or application that brings innovation to the field, or applies a known idea, method, design or application to a different field, researches, comprehends, designs, adapts and applies an original subject. | X | |||||
| 6 | He/she writes the report of the research he/she participated in. It publishes in a national/internationally accepted peer-reviewed journal and presents it at scientific meetings. | X | |||||
| 7 | It contributes to the progress in its field by independently carrying out an original work that brings innovations to its field, develops a new idea, method, design or application, or applies a known idea, method, design or application to a different field. | ||||||
| 8 | Develops new thoughts and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. | X | |||||
| 9 | Participates in meetings related to the field of histology, presents papers, participates in discussions, gives conferences, and publishes his studies in reputable journals specific to the field. | ||||||
| 10 | Collects, interprets, applies and announces data related to histology and embryology. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 6 | 84 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 4 | 20 | 80 | |||
| Term Project | 3 | 10 | 30 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 15 | 15 | |||
| General Exam | 1 | 20 | 20 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 229 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(229/30) | 8 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| EXPERIMENTAL ANIMAL MODELS | - | Spring Semester | 2+4 | 4 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Bircan KOLBAŞI |
| Name of Lecturer(s) | Prof.Dr. İlknur KESKİN, Assist.Prof. Bircan KOLBAŞI |
| Assistant(s) | |
| Aim | The aim of the course is to teach how to induce various disease models in mice and rats, to construct experimental disease models in animals and to apply treatment methods in line with the acquired knowledge. |
| Course Content | This course contains; Creating a DM model with streptozocin,Establishing a liver failure model with CCl4,Creation of ischemia-reperfusion models,Establishment of experimental sepsis or adhesion models,Creation of intraabdominal sepsis models,Establishment of experimental shock models,Midterm,Resection – anastomosis – creation of burst pressure models,Creation of transplantation models,Establishment of experimental models of obstructive jaundice,Creation of experimental pancreatitis models,Establishment of experimental cholangitis models,Creation of peritoneal adhesion models,Final exam. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explain the design of the experimental model of liver failure with CCl4. | 14, 9 | A, E |
| Explains how to create an experimental model with streptozocin. | 14, 9 | A, E |
| Explains ischemia-reperfusion model creation. | 14, 9 | A, E |
| Explains how to create an experimental sepsis or adhesion model. | 14, 9 | A, E |
| Explains how to create intraabdominal sepsis models. | 14, 9 | A, E |
| Explain experimental shock models. | 14, 9 | A, E |
| Explains resection – anastomosis – burst pressure models. | 14, 9 | A, E |
| Explains the transplantation models. | 14, 9 | A, E |
| Explain experimental models of obstructive jaundice. | 14, 9 | A, E |
| Explains experimental models of pancreatitis. | 14, 9 | A, E |
| Explains how to create experimental cholangitis models. | 14, 9 | A, E |
| Explains creating peritoneal adhesion models. | 14, 9 | A, E |
| Teaching Methods: | 14: Self Study Method, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Creating a DM model with streptozocin | Reading the relevant course presentation |
| 2 | Establishing a liver failure model with CCl4 | Reading the relevant course presentation |
| 3 | Creation of ischemia-reperfusion models | Reading the relevant course presentation |
| 4 | Establishment of experimental sepsis or adhesion models | Reading the relevant course presentation |
| 5 | Creation of intraabdominal sepsis models | Reading the relevant course presentation |
| 6 | Establishment of experimental shock models | Reading the relevant course presentation |
| 7 | Midterm | |
| 8 | Resection – anastomosis – creation of burst pressure models | Reading the relevant course presentation |
| 9 | Creation of transplantation models | Reading the relevant course presentation |
| 10 | Establishment of experimental models of obstructive jaundice | Reading the relevant course presentation |
| 11 | Creation of experimental pancreatitis models | Reading the relevant course presentation |
| 12 | Establishment of experimental cholangitis models | Reading the relevant course presentation |
| 13 | Creation of peritoneal adhesion models | Reading the relevant course presentation |
| 14 | Final exam |
| Resources |
| PROF.DR.HASAN BESIM, DENEYSEL HAYVAN MODELLERI, Current literature, Lecture notes |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Develops and deepens current and advanced knowledge in the field of histology with original thought and research at the level of expertise and reaches original definitions that will bring innovation to the field. | X | |||||
| 2 | Defines cell and tissue at an advanced level (ultrastructural). | ||||||
| 3 | Knows the embryological details about the development of systems at an advanced level. | ||||||
| 4 | Comprehends the interdisciplinary interaction that the field is related to; reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | X | |||||
| 5 | Develops a new idea, method, design or application that brings innovation to the field, or applies a known idea, method, design or application to a different field, researches, comprehends, designs, adapts and applies an original subject. | X | |||||
| 6 | He/she writes the report of the research he/she participated in. It publishes in a national/internationally accepted peer-reviewed journal and presents it at scientific meetings. | X | |||||
| 7 | It contributes to the progress in its field by independently carrying out an original work that brings innovations to its field, develops a new idea, method, design or application, or applies a known idea, method, design or application to a different field. | ||||||
| 8 | Develops new thoughts and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. | X | |||||
| 9 | Participates in meetings related to the field of histology, presents papers, participates in discussions, gives conferences, and publishes his studies in reputable journals specific to the field. | ||||||
| 10 | Collects, interprets, applies and announces data related to histology and embryology. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |