The aim of this course is to teach drug pharmacokinetics and pharmacodynamics, drug effect, factors that change drug effect, new drug development and basic concepts of registration and pharmacovigilance.
Course Content
This course contains; Introduction to pharmacology.,Pharmaceutical forms of drugs.,Drug administration ways.,Passage of drugs through biological membranes and absorption.,Distribution of drugs.,Biotransformation of drugs.,Excretion of drugs.,Factors that change the effect of drugs.,Pharmacogenetics.,Drug interactions - I.,Drug interactions - II.,Dose-concentration relationship.,Dose-effect relationship.,Mechanism of action of drugs..
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
Explains absorption, distribution, metabolism and excretion of drugs.
10, 16, 19, 9
A, D, E, F, H
Explains the dose-concentration and dose-effect relationship of drugs.
10, 16, 19, 9
A, D, E, F, H
Explains the basic features of the drug effect
10, 16, 19, 9
A, D, E, F, H
Explains the drug administration ways, the factors that change drug's effect and interactions.
10, 16, 19
A, D, E, F, H
Explains about bioavailability and bioequivalence.
10, 16, 19, 9
A, D, E, F, H
Explains preclinical and clinical studies in new drug development.
10, 16, 19, 9
A, D, E, F, H
Explains the basic principles of licensing pharmaceutical preparations.
A: Traditional Written Exam, D: Oral Exam, E: Homework, F: Project Task, H: Performance Task
Course Outline
Order
Subjects
Preliminary Work
1
Introduction to pharmacology.
Preparation for the previously given lecture note.
2
Pharmaceutical forms of drugs.
Preparation for the previously given lecture note.
3
Drug administration ways.
Preparation for the previously given lecture note.
4
Passage of drugs through biological membranes and absorption.
Preparation for the previously given lecture note.
5
Distribution of drugs.
Preparation for the previously given lecture note.
6
Biotransformation of drugs.
Preparation for the previously given lecture note.
7
Excretion of drugs.
Preparation for the previously given lecture note.
8
Factors that change the effect of drugs.
Preparation for the previously given lecture note.
9
Pharmacogenetics.
Preparation for the previously given lecture note.
10
Drug interactions - I.
Preparation for the previously given lecture note.
11
Drug interactions - II.
Preparation for the previously given lecture note.
12
Dose-concentration relationship.
Preparation for the previously given lecture note.
13
Dose-effect relationship.
Preparation for the previously given lecture note.
14
Mechanism of action of drugs.
Preparation for the previously given lecture note.
Resources
Goodman & Gilman’nın Tedavinin Farmakolojik Temeli - / Laurence L.Brunton - John S.Lazo - Keith L.Parker Nobel Tıp Kitapevleri Yayınları,İstanbul, 2008
Katzung & Trevor's Pharmacology Examination and Board Review: Eighth Edition McGraw-Hill Medical Publishing USA, 2008.
Rasyonel Tedavi Yönünden Tıbbi Farmakoloji 13. Baskı - Prof.Dr. Oğuz Kayaalp, Pelikan Yayınları, 2012.
Sağlık Bilimleri için Farmakoloji- Dr. Öğr. Ü. A. Arzu SAYIN ŞAKUL, İstanbul Tıp Yayınevi-2021
Lecture notes given to the students.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
He/she knows the basic functions and working mechanisms of organs and systems and can explain each system as a course subject.
X
2
He/she can dissect different parts of cadavers alone, identify organs and other structures on them, and lecture on them
3
He/she can design a project on a subject individually, take an active role in that project, compose a scientific article, and publish.
X
4
She/he can take an active role in multidisciplinary studies related to her/his branch.
X
5
He/she can identify normal anatomical structures on radiogram, MR and CT images and provide anatomical explanations for pathological conditions
6
He/she understands the relationship of anatomy with other basic medicine and clinical branches and takes part in projects.
X
7
He/she can speak at least one foreign language effectively, he/she can follow international publications in his/her branch or other branchs.
X
8
He/she can understand the topographic anatomy, surface projections and courses of organs and structures.
9
He/she can can make a presentation about his/her branch or other researchers branchs.
X
10
He/she can analyzes herself/himself by following current research topics.
X
11
He/she effectively fulfills the responsibility given within the team in multidisciplinary studies.
X
12
He/she can solve clinical problems and explain anatomically.
X
13
He/she can define the basic microanatomical structures in the human body, tissues, organs and systems.
X
14
He/she can make trust-based relationships with students and get them interest in the lesson.
X
Assessment Methods
Contribution Level
Absolute Evaluation
Rate of Midterm Exam to Success
50
Rate of Final Exam to Success
50
Total
100
ECTS / Workload Table
Activities
Number of
Duration(Hour)
Total Workload(Hour)
Course Hours
14
2
28
Course Hours
0
0
0
Guided Problem Solving
2
5
10
Guided Problem Solving
0
0
0
Resolution of Homework Problems and Submission as a Report
4
2
8
Resolution of Homework Problems and Submission as a Report
0
0
0
Term Project
0
0
0
Term Project
1
16
16
Presentation of Project / Seminar
0
0
0
Presentation of Project / Seminar
0
0
0
Quiz
0
0
0
Quiz
7
4
28
Midterm Exam
1
40
40
Midterm Exam
0
0
0
General Exam
0
0
0
General Exam
1
50
50
Performance Task, Maintenance Plan
0
0
0
Performance Task, Maintenance Plan
0
0
0
Total Workload(Hour)
180
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(180/30)
6
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.
Detail Informations of the Course
Course Description
Course
Code
Semester
T+P (Hour)
Credit
ECTS
GENERAL PHARMACOLOGY
-
Fall Semester
2+0
2
6
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of Course
Turkish
Course Level
Third Cycle (Doctorate Degree)
Course Type
Elective
Course Coordinator
Assoc.Prof. Ayşe Arzu ŞAKUL
Name of Lecturer(s)
Assoc.Prof. Ayşe Arzu ŞAKUL
Assistant(s)
Aim
The aim of this course is to teach drug pharmacokinetics and pharmacodynamics, drug effect, factors that change drug effect, new drug development and basic concepts of registration and pharmacovigilance.
Course Content
This course contains; Introduction to pharmacology.,Pharmaceutical forms of drugs.,Drug administration ways.,Passage of drugs through biological membranes and absorption.,Distribution of drugs.,Biotransformation of drugs.,Excretion of drugs.,Factors that change the effect of drugs.,Pharmacogenetics.,Drug interactions - I.,Drug interactions - II.,Dose-concentration relationship.,Dose-effect relationship.,Mechanism of action of drugs..
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
Explains absorption, distribution, metabolism and excretion of drugs.
10, 16, 19, 9
A, D, E, F, H
Explains the dose-concentration and dose-effect relationship of drugs.
10, 16, 19, 9
A, D, E, F, H
Explains the basic features of the drug effect
10, 16, 19, 9
A, D, E, F, H
Explains the drug administration ways, the factors that change drug's effect and interactions.
10, 16, 19
A, D, E, F, H
Explains about bioavailability and bioequivalence.
10, 16, 19, 9
A, D, E, F, H
Explains preclinical and clinical studies in new drug development.
10, 16, 19, 9
A, D, E, F, H
Explains the basic principles of licensing pharmaceutical preparations.
A: Traditional Written Exam, D: Oral Exam, E: Homework, F: Project Task, H: Performance Task
Course Outline
Order
Subjects
Preliminary Work
1
Introduction to pharmacology.
Preparation for the previously given lecture note.
2
Pharmaceutical forms of drugs.
Preparation for the previously given lecture note.
3
Drug administration ways.
Preparation for the previously given lecture note.
4
Passage of drugs through biological membranes and absorption.
Preparation for the previously given lecture note.
5
Distribution of drugs.
Preparation for the previously given lecture note.
6
Biotransformation of drugs.
Preparation for the previously given lecture note.
7
Excretion of drugs.
Preparation for the previously given lecture note.
8
Factors that change the effect of drugs.
Preparation for the previously given lecture note.
9
Pharmacogenetics.
Preparation for the previously given lecture note.
10
Drug interactions - I.
Preparation for the previously given lecture note.
11
Drug interactions - II.
Preparation for the previously given lecture note.
12
Dose-concentration relationship.
Preparation for the previously given lecture note.
13
Dose-effect relationship.
Preparation for the previously given lecture note.
14
Mechanism of action of drugs.
Preparation for the previously given lecture note.
Resources
Goodman & Gilman’nın Tedavinin Farmakolojik Temeli - / Laurence L.Brunton - John S.Lazo - Keith L.Parker Nobel Tıp Kitapevleri Yayınları,İstanbul, 2008
Katzung & Trevor's Pharmacology Examination and Board Review: Eighth Edition McGraw-Hill Medical Publishing USA, 2008.
Rasyonel Tedavi Yönünden Tıbbi Farmakoloji 13. Baskı - Prof.Dr. Oğuz Kayaalp, Pelikan Yayınları, 2012.
Sağlık Bilimleri için Farmakoloji- Dr. Öğr. Ü. A. Arzu SAYIN ŞAKUL, İstanbul Tıp Yayınevi-2021
Lecture notes given to the students.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
He/she knows the basic functions and working mechanisms of organs and systems and can explain each system as a course subject.
X
2
He/she can dissect different parts of cadavers alone, identify organs and other structures on them, and lecture on them
3
He/she can design a project on a subject individually, take an active role in that project, compose a scientific article, and publish.
X
4
She/he can take an active role in multidisciplinary studies related to her/his branch.
X
5
He/she can identify normal anatomical structures on radiogram, MR and CT images and provide anatomical explanations for pathological conditions
6
He/she understands the relationship of anatomy with other basic medicine and clinical branches and takes part in projects.
X
7
He/she can speak at least one foreign language effectively, he/she can follow international publications in his/her branch or other branchs.
X
8
He/she can understand the topographic anatomy, surface projections and courses of organs and structures.
9
He/she can can make a presentation about his/her branch or other researchers branchs.
X
10
He/she can analyzes herself/himself by following current research topics.
X
11
He/she effectively fulfills the responsibility given within the team in multidisciplinary studies.
X
12
He/she can solve clinical problems and explain anatomically.
X
13
He/she can define the basic microanatomical structures in the human body, tissues, organs and systems.
X
14
He/she can make trust-based relationships with students and get them interest in the lesson.
