Studying the biochemical mechanisms via proteomics methodologies.
Course Content
This course contains; Introduction to Proteomics,Introduction to Proteomics,The reason behind the fast development of proteomics,The instruments used in proteomics research (I),The instruments used in proteomics research (II),Proteomics research in tumor biomarker discovery.,Proteomics applications regarding muscle and cartilage cells,Proteomics research in personalised medicine (I),Proteomics research in personalised medicine (II),Proteomics applications in immunological response and prognostic evaluation of transplantation (I),Proteomics applications in immunological response and prognostic evaluation of transplantation (II),Cancer and prognostic proteomics studies (I),Cancer and prognostic proteomics studies (II),Proteomics applications in classifications of microorganisms.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
1-Explains the structure, function and the properties of the proteins
10, 11, 16, 19, 6, 9
A, D, E
2.Question the characteristics of the metabolism of each amino acid, their behaviour according to the properties of proteins and their behaviour at different pHs.
10, 11, 16, 19, 6, 9
A, D, E
3.Explains PK values
10, 11, 16, 19, 6, 9
A, D, E
4.Explains protein structures and structural properties.
10, 11, 16, 19, 6, 9
A, D, E
5.explains the digestion, absorption and degradation of proteins in the cell.
10, 11, 16, 19, 6, 9
A, D, E
6.explains the relationship and properties of ubiquitins, plasma proteins and intracellular proteins.
10, 11, 16, 19, 6, 9
A, D, E
7.Evaluates the targets of proteomics, interpretation of proteomics data in pathological conditions.
10, 11, 16, 19, 6, 9
A, D, E
8.Explains the place of proteomics research in cancer studies.
10, 11, 16, 19, 6, 9
A, D, E
9.Explains proteomics studies for new drug discovery at an advanced level.
A: Traditional Written Exam, D: Oral Exam, E: Homework
Course Outline
Order
Subjects
Preliminary Work
1
Introduction to Proteomics
1, 2, 3
2
Introduction to Proteomics
1, 2, 3
3
The reason behind the fast development of proteomics
1, 2, 3
4
The instruments used in proteomics research (I)
1, 2, 3
5
The instruments used in proteomics research (II)
1, 2, 3
6
Proteomics research in tumor biomarker discovery.
1, 2, 3
7
Proteomics applications regarding muscle and cartilage cells
1, 2, 3
8
Proteomics research in personalised medicine (I)
1, 2, 3
9
Proteomics research in personalised medicine (II)
1, 2, 3
10
Proteomics applications in immunological response and prognostic evaluation of transplantation (I)
1, 2, 3
11
Proteomics applications in immunological response and prognostic evaluation of transplantation (II)
1, 2, 3
12
Cancer and prognostic proteomics studies (I)
1, 2, 3
13
Cancer and prognostic proteomics studies (II)
1, 2, 3
14
Proteomics applications in classifications of microorganisms
1, 2, 3
Resources
Lecture notes
Resources obtained from the literature
Lieberman M, Marks AD. Marks’ Basic medical biochemistry 3. Baskı, Lippincott Williams &Wilkins, 2010.
Aminoasidler ve proteinler. Klinik Biyokimya Eds. Emekli & Yiğitbaşı, Medipol Üniversitesi Yayınları, Akademi Matbaası, 2015.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
Defines macro and micromolecules in cell and body fluids at an advanced level.
X
2
Knows how to store and protect the material to be analyzed.
X
3
Knows how to identify molecules found in cells and body fluids.
X
4
Knows the principles of technologies to be used for routine and research purposes.
X
5
Knows how to evaluate the results of the study, interprets and questions.
X
6
Knows how to use field-specific tools and equipment
X
7
Knows how to access and interpret field-specific resources and information
X
8
Shares information with disciplines related to the field
X
9
Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals.
X
10
Solves a scientific and technical problem, knows where to get help.
X
11
Takes responsibility in joint scientific studies, contributes and works in harmony.
X
12
Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field.
X
13
Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially.
X
14
Can take part in management activities, evaluate the results obtained to improve quality
X
Assessment Methods
Contribution Level
Absolute Evaluation
Rate of Midterm Exam to Success
50
Rate of Final Exam to Success
50
Total
100
ECTS / Workload Table
Activities
Number of
Duration(Hour)
Total Workload(Hour)
Course Hours
14
2
28
Guided Problem Solving
14
7
98
Resolution of Homework Problems and Submission as a Report
0
0
0
Term Project
2
3
6
Presentation of Project / Seminar
2
4
8
Quiz
0
0
0
Midterm Exam
1
4
4
General Exam
1
4
4
Performance Task, Maintenance Plan
0
0
0
Total Workload(Hour)
148
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(148/30)
5
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.
Studying the biochemical mechanisms via proteomics methodologies.
Course Content
This course contains; Introduction to Proteomics,Introduction to Proteomics,The reason behind the fast development of proteomics,The instruments used in proteomics research (I),The instruments used in proteomics research (II),Proteomics research in tumor biomarker discovery.,Proteomics applications regarding muscle and cartilage cells,Proteomics research in personalised medicine (I),Proteomics research in personalised medicine (II),Proteomics applications in immunological response and prognostic evaluation of transplantation (I),Proteomics applications in immunological response and prognostic evaluation of transplantation (II),Cancer and prognostic proteomics studies (I),Cancer and prognostic proteomics studies (II),Proteomics applications in classifications of microorganisms.
Dersin Öğrenme Kazanımları
Teaching Methods
Assessment Methods
1-Explains the structure, function and the properties of the proteins
10, 11, 16, 19, 6, 9
A, D, E
2.Question the characteristics of the metabolism of each amino acid, their behaviour according to the properties of proteins and their behaviour at different pHs.
10, 11, 16, 19, 6, 9
A, D, E
3.Explains PK values
10, 11, 16, 19, 6, 9
A, D, E
4.Explains protein structures and structural properties.
10, 11, 16, 19, 6, 9
A, D, E
5.explains the digestion, absorption and degradation of proteins in the cell.
10, 11, 16, 19, 6, 9
A, D, E
6.explains the relationship and properties of ubiquitins, plasma proteins and intracellular proteins.
10, 11, 16, 19, 6, 9
A, D, E
7.Evaluates the targets of proteomics, interpretation of proteomics data in pathological conditions.
10, 11, 16, 19, 6, 9
A, D, E
8.Explains the place of proteomics research in cancer studies.
10, 11, 16, 19, 6, 9
A, D, E
9.Explains proteomics studies for new drug discovery at an advanced level.
A: Traditional Written Exam, D: Oral Exam, E: Homework
Course Outline
Order
Subjects
Preliminary Work
1
Introduction to Proteomics
1, 2, 3
2
Introduction to Proteomics
1, 2, 3
3
The reason behind the fast development of proteomics
1, 2, 3
4
The instruments used in proteomics research (I)
1, 2, 3
5
The instruments used in proteomics research (II)
1, 2, 3
6
Proteomics research in tumor biomarker discovery.
1, 2, 3
7
Proteomics applications regarding muscle and cartilage cells
1, 2, 3
8
Proteomics research in personalised medicine (I)
1, 2, 3
9
Proteomics research in personalised medicine (II)
1, 2, 3
10
Proteomics applications in immunological response and prognostic evaluation of transplantation (I)
1, 2, 3
11
Proteomics applications in immunological response and prognostic evaluation of transplantation (II)
1, 2, 3
12
Cancer and prognostic proteomics studies (I)
1, 2, 3
13
Cancer and prognostic proteomics studies (II)
1, 2, 3
14
Proteomics applications in classifications of microorganisms
1, 2, 3
Resources
Lecture notes
Resources obtained from the literature
Lieberman M, Marks AD. Marks’ Basic medical biochemistry 3. Baskı, Lippincott Williams &Wilkins, 2010.
Aminoasidler ve proteinler. Klinik Biyokimya Eds. Emekli & Yiğitbaşı, Medipol Üniversitesi Yayınları, Akademi Matbaası, 2015.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
Defines macro and micromolecules in cell and body fluids at an advanced level.
X
2
Knows how to store and protect the material to be analyzed.
X
3
Knows how to identify molecules found in cells and body fluids.
X
4
Knows the principles of technologies to be used for routine and research purposes.
X
5
Knows how to evaluate the results of the study, interprets and questions.
X
6
Knows how to use field-specific tools and equipment
X
7
Knows how to access and interpret field-specific resources and information
X
8
Shares information with disciplines related to the field
X
9
Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals.
X
10
Solves a scientific and technical problem, knows where to get help.
X
11
Takes responsibility in joint scientific studies, contributes and works in harmony.
X
12
Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field.
X
13
Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially.
X
14
Can take part in management activities, evaluate the results obtained to improve quality
