Ders Detayı
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| DIABETES BIOCHEMISTRY II | - | Fall Semester | 2+0 | 2 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Çağrı ÇAKICI |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Assoc.Prof. Sultan Sibel ERDEM, Prof.Dr. Türkan YİĞİTBAŞI, Assist.Prof. Gözde ÜLFER |
| Assistant(s) | |
| Aim | To teach advanced biochemistry of diabetes and improve analytical concepts |
| Course Content | This course contains; Classification of diabetes mellitus,Hyperglycemia and hypoglycemia,Fate of glucose after entering the blood,Regulation of glucose metabolism,Insulin synthesis and mechanism of action,Laboratroy findings in hyperglycemia,Criteria for testing for prediabetes and diabetes,Diabetes and non-enzymatic glycation,The relationship between diabetes and atherosclerosis,Diabetes and fat metabolism,Animal models in the study of diabetes,Obesity and diabetes,Glucose measurement tests in diabetes,Keton bodies and microalbuminuria in diabetes. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course, the students will be able to: 1-Can compare the biochemical mechanism of diabetes mellitus | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explain the cause of tip 1 diabetes mellitus. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Explain the cause of tip 2 diabetes mellitus. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3.Question associated secondary condition for diabetes mellitus | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4.Describe gestational diabetes. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2-Can compare laboratory findings in hyperglycemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1.Question blood and urine glucose level | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Explains serum and urine osmolality | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.4.Analyse blood and urine pH analyzes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.5.Question electrolyte imbalance in the blood during diabetes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.6.Explains the diabetes criteria for diabetes and prediabetes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.7.Question the microalbuminuria in diabetes mellitus | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Can solve regulation blood glucose | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2.Question storage of glucose | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4- Can recognise fat metabolism in diabetes and obesity | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Question the relation of fat metabolism and exercise | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2.Question the relation of between energy metabolism and exercise | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3.Evaulate leptin in fat metabolism | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4.Evaulate other hormones on fat and glucose metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.Interpret glucose and HbAic measurements | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1.Question the glucose oxidase method | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2.Question the hexokinase method | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3.Question chemical methods | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.4.Question the measurement of glycosylation proteins | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.5.Describe experimental diabetes in diabetes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.Develop analytical thoughts with this information | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7-Reach printed and electronic information sources, read and write information at a level that can follow developments in biochemistry and related fields. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3 Describe ketones bodies in serum and urine | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1. Questions the ways of using glucose. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3. Questions the sources of glucose in blood | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Questions the ways of using glucose. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.5. Questions the relation of between diabetes and atherosclerosis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Classification of diabetes mellitus | 1, 2, 3 |
| 2 | Hyperglycemia and hypoglycemia | 1, 2, 3 |
| 3 | Fate of glucose after entering the blood | 1, 2, 3 |
| 4 | Regulation of glucose metabolism | 1, 2, 3 |
| 5 | Insulin synthesis and mechanism of action | 1, 2, 3 |
| 6 | Laboratroy findings in hyperglycemia | 1, 2, 3 |
| 7 | Criteria for testing for prediabetes and diabetes | 1, 2, 3 |
| 8 | Diabetes and non-enzymatic glycation | 1, 2, 3 |
| 9 | The relationship between diabetes and atherosclerosis | 1, 2, 3 |
| 10 | Diabetes and fat metabolism | 1, 2, 3 |
| 11 | Animal models in the study of diabetes | 1, 2, 3 |
| 12 | Obesity and diabetes | 1, 2, 3 |
| 13 | Glucose measurement tests in diabetes | 1, 2, 3 |
| 14 | Keton bodies and microalbuminuria in diabetes | 1, 2, 3 |
| Resources |
| 1) Prof. Dr. Nesrin Emekli ve Doç.Dr. Türkan Yiğitbaşı'nın ders kitapları 2) Biyokimya Prof. Dr. Figen Gürdöl ve Evin Ademoğlu 3) Theory, Analysis Correlation Clinical Chemistry Ed. Lawrence A. Kaplan ve Amadeo Pesce |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Defines macro and micromolecules in cell and body fluids at an advanced level. | X | |||||
| 2 | Knows how to store and protect the material to be analyzed. | X | |||||
| 3 | Knows how to identify molecules found in cells and body fluids. | X | |||||
| 4 | Knows the principles of technologies to be used for routine and research purposes. | X | |||||
| 5 | Knows how to evaluate the results of the study, interprets and questions. | X | |||||
| 6 | Knows how to use field-specific tools and equipment | X | |||||
| 7 | Knows how to access and interpret field-specific resources and information | X | |||||
| 8 | Shares information with disciplines related to the field | X | |||||
| 9 | Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals. | X | |||||
| 10 | Solves a scientific and technical problem, knows where to get help. | X | |||||
| 11 | Takes responsibility in joint scientific studies, contributes and works in harmony. | X | |||||
| 12 | Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field. | X | |||||
| 13 | Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially. | X | |||||
| 14 | Can take part in management activities, evaluate the results obtained to improve quality | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 14 | 2 | 28 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 2 | 3 | 6 | |||
| Presentation of Project / Seminar | 2 | 2 | 4 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 35 | 35 | |||
| General Exam | 1 | 45 | 45 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 146 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(146/30) | 5 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| DIABETES BIOCHEMISTRY II | - | Fall Semester | 2+0 | 2 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Çağrı ÇAKICI |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Assoc.Prof. Sultan Sibel ERDEM, Prof.Dr. Türkan YİĞİTBAŞI, Assist.Prof. Gözde ÜLFER |
| Assistant(s) | |
| Aim | To teach advanced biochemistry of diabetes and improve analytical concepts |
| Course Content | This course contains; Classification of diabetes mellitus,Hyperglycemia and hypoglycemia,Fate of glucose after entering the blood,Regulation of glucose metabolism,Insulin synthesis and mechanism of action,Laboratroy findings in hyperglycemia,Criteria for testing for prediabetes and diabetes,Diabetes and non-enzymatic glycation,The relationship between diabetes and atherosclerosis,Diabetes and fat metabolism,Animal models in the study of diabetes,Obesity and diabetes,Glucose measurement tests in diabetes,Keton bodies and microalbuminuria in diabetes. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course, the students will be able to: 1-Can compare the biochemical mechanism of diabetes mellitus | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explain the cause of tip 1 diabetes mellitus. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Explain the cause of tip 2 diabetes mellitus. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3.Question associated secondary condition for diabetes mellitus | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4.Describe gestational diabetes. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2-Can compare laboratory findings in hyperglycemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1.Question blood and urine glucose level | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Explains serum and urine osmolality | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.4.Analyse blood and urine pH analyzes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.5.Question electrolyte imbalance in the blood during diabetes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.6.Explains the diabetes criteria for diabetes and prediabetes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.7.Question the microalbuminuria in diabetes mellitus | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Can solve regulation blood glucose | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2.Question storage of glucose | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4- Can recognise fat metabolism in diabetes and obesity | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Question the relation of fat metabolism and exercise | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2.Question the relation of between energy metabolism and exercise | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3.Evaulate leptin in fat metabolism | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4.Evaulate other hormones on fat and glucose metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.Interpret glucose and HbAic measurements | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1.Question the glucose oxidase method | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2.Question the hexokinase method | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3.Question chemical methods | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.4.Question the measurement of glycosylation proteins | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.5.Describe experimental diabetes in diabetes | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.Develop analytical thoughts with this information | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7-Reach printed and electronic information sources, read and write information at a level that can follow developments in biochemistry and related fields. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3 Describe ketones bodies in serum and urine | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1. Questions the ways of using glucose. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3. Questions the sources of glucose in blood | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Questions the ways of using glucose. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.5. Questions the relation of between diabetes and atherosclerosis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Classification of diabetes mellitus | 1, 2, 3 |
| 2 | Hyperglycemia and hypoglycemia | 1, 2, 3 |
| 3 | Fate of glucose after entering the blood | 1, 2, 3 |
| 4 | Regulation of glucose metabolism | 1, 2, 3 |
| 5 | Insulin synthesis and mechanism of action | 1, 2, 3 |
| 6 | Laboratroy findings in hyperglycemia | 1, 2, 3 |
| 7 | Criteria for testing for prediabetes and diabetes | 1, 2, 3 |
| 8 | Diabetes and non-enzymatic glycation | 1, 2, 3 |
| 9 | The relationship between diabetes and atherosclerosis | 1, 2, 3 |
| 10 | Diabetes and fat metabolism | 1, 2, 3 |
| 11 | Animal models in the study of diabetes | 1, 2, 3 |
| 12 | Obesity and diabetes | 1, 2, 3 |
| 13 | Glucose measurement tests in diabetes | 1, 2, 3 |
| 14 | Keton bodies and microalbuminuria in diabetes | 1, 2, 3 |
| Resources |
| 1) Prof. Dr. Nesrin Emekli ve Doç.Dr. Türkan Yiğitbaşı'nın ders kitapları 2) Biyokimya Prof. Dr. Figen Gürdöl ve Evin Ademoğlu 3) Theory, Analysis Correlation Clinical Chemistry Ed. Lawrence A. Kaplan ve Amadeo Pesce |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Defines macro and micromolecules in cell and body fluids at an advanced level. | X | |||||
| 2 | Knows how to store and protect the material to be analyzed. | X | |||||
| 3 | Knows how to identify molecules found in cells and body fluids. | X | |||||
| 4 | Knows the principles of technologies to be used for routine and research purposes. | X | |||||
| 5 | Knows how to evaluate the results of the study, interprets and questions. | X | |||||
| 6 | Knows how to use field-specific tools and equipment | X | |||||
| 7 | Knows how to access and interpret field-specific resources and information | X | |||||
| 8 | Shares information with disciplines related to the field | X | |||||
| 9 | Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals. | X | |||||
| 10 | Solves a scientific and technical problem, knows where to get help. | X | |||||
| 11 | Takes responsibility in joint scientific studies, contributes and works in harmony. | X | |||||
| 12 | Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field. | X | |||||
| 13 | Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially. | X | |||||
| 14 | Can take part in management activities, evaluate the results obtained to improve quality | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |