Ders Detayı
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ANAEMIA BIOCHEMISTRY | - | Fall Semester | 1+2 | 2 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Gözde ÜLFER |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Nesrin HELVACI YILMAZ, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Gözde ÜLFER, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI |
| Assistant(s) | |
| Aim | Learning the biochemical reactions occurred during the anemia process, observing detection methods and understanding the importance of hemoglobin and iron metabolism in anemia |
| Course Content | This course contains; Hemogram,Hematopoiesis,Eritrocycye metabolism,Eritrocycte membrane proteins and its importance,Hemoglobin synthesis,Porfirias,Hemoglobin electrophoresis,HbAıc measurements,Iron metabolism,Cyanokobalamin (B12) and Folic acid (B9) metabolism and relation with anemia,The biochemical approach to the classification of anemias-1,The biochemical approach to the classification of anemias-1,Biochemistry in transfusion medicine,Tissue banking and biochemistry. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course, the students will be able to: 1-Explain the relation of the structure of hemoglobin and its relation with anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explain the detailed structure of hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Explain the function and the importance of the hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3.Explain the synthesis of the hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4.Describe the normal types of hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2- Explain the abnormal types of hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1.Explain the methods that are used to characterize abnormal hemoglobin types. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Explain hemogram method in a detailed way. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3.Describe hemoglobin electrophoresis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Desribe and classify hemoglobinopathies. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1.Explain sickle cell anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3.Describe hemoglobins with abnormal oxygen affinities. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4.Explain the thalassemia and classify. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4-Describe the tests used for anemia diagnosis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Explainthe details of hematocrit measurement. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2.Describes the method of erythrocyte calculation. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3.comprasion the anemia with hemoglobin measurement and erythrocyte index. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4.Describe the automatic complete blood cell count devices. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5-Classify the types of anemias. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1.Question the relation of morphological and classification of anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2.Questions the classification of anemias regarding their etiology. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3.Evaulate the classification of anemia in biochemical aspect. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.Compare the erythrocyte metabolism with anemias. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.1.Evaluate erythrocyte metabolism in biochemical aspect | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.2.Explain the importance of erythrocyte membrane proteins. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.3.Describes the porphyrias. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7-Evaluate iron metabolism in biochemical aspect. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7.1.Describe the iron-deficiency dependent anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7.2.Explain the iron in nutrition and its income. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7.3.Describe the absorption iron by erythrocytes and its transportation to bone marrow. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 8-Questions the relationship of cyanocobalamin (B12) and folic acid (B9) metabolism with anemia | 10, 11, 16, 19, 6, 9 | D, E |
| 8.1.Describes B12 deficiency anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 8.2.Explain the folic-acid deficiency dependent anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 9-Explainthe importance of biochmistry in transfusion medicine. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 10-Describe the relationshiop of biochemistry and tissue banking. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 10-Describe the relationshiop of biochemistry and tissue banking. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2. Question the variants of sickle cell anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Hemogram | 1, 2, 3, 4, 5 |
| 2 | Hematopoiesis | 1, 2, 3, 4, 5 |
| 3 | Eritrocycye metabolism | 1, 2, 3, 4, 5 |
| 4 | Eritrocycte membrane proteins and its importance | 1, 2, 3, 4, 5 |
| 5 | Hemoglobin synthesis | 1, 2, 3, 4, 5 |
| 6 | Porfirias | 1, 2, 3, 4, 5 |
| 7 | Hemoglobin electrophoresis | 1, 2, 3, 4, 5 |
| 8 | HbAıc measurements | 1, 2, 3, 4, 5 |
| 9 | Iron metabolism | 1, 2, 3, 4, 5 |
| 10 | Cyanokobalamin (B12) and Folic acid (B9) metabolism and relation with anemia | 1, 2, 3, 4, 5 |
| 11 | The biochemical approach to the classification of anemias-1 | 1, 2, 3, 4, 5 |
| 12 | The biochemical approach to the classification of anemias-1 | 1, 2, 3, 4, 5 |
| 13 | Biochemistry in transfusion medicine | 1, 2, 3, 4, 5 |
| 14 | Tissue banking and biochemistry | 1, 2, 3, 4, 5 |
| Resources |
| Published books of Prof. Dr.Nesrin Emekli, Assoc. Prof. Dr. Türkan Yiğitbaşı |
| Henry Williams ve Wintrobe hematoloji Marks 831 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Defines macro and micromolecules in cell and body fluids at an advanced level. | ||||||
| 2 | Knows how to store and protect the material to be analyzed. | ||||||
| 3 | Knows how to identify molecules found in cells and body fluids. | ||||||
| 4 | Knows the principles of technologies to be used for routine and research purposes. | ||||||
| 5 | Knows how to evaluate the results of the study, interprets and questions. | ||||||
| 6 | Knows how to use field-specific tools and equipment | ||||||
| 7 | Knows how to access and interpret field-specific resources and information | ||||||
| 8 | Shares information with disciplines related to the field | ||||||
| 9 | Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals. | ||||||
| 10 | Solves a scientific and technical problem, knows where to get help. | ||||||
| 11 | Takes responsibility in joint scientific studies, contributes and works in harmony. | ||||||
| 12 | Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field. | ||||||
| 13 | Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially. | ||||||
| 14 | Can take part in management activities, evaluate the results obtained to improve quality | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 1 | 14 | |||
| Guided Problem Solving | 14 | 6 | 84 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 2 | 2 | 4 | |||
| Presentation of Project / Seminar | 2 | 1 | 2 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 3 | 3 | |||
| General Exam | 1 | 5 | 5 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 112 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(112/30) | 4 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ANAEMIA BIOCHEMISTRY | - | Fall Semester | 1+2 | 2 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Gözde ÜLFER |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Nesrin HELVACI YILMAZ, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Gözde ÜLFER, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI |
| Assistant(s) | |
| Aim | Learning the biochemical reactions occurred during the anemia process, observing detection methods and understanding the importance of hemoglobin and iron metabolism in anemia |
| Course Content | This course contains; Hemogram,Hematopoiesis,Eritrocycye metabolism,Eritrocycte membrane proteins and its importance,Hemoglobin synthesis,Porfirias,Hemoglobin electrophoresis,HbAıc measurements,Iron metabolism,Cyanokobalamin (B12) and Folic acid (B9) metabolism and relation with anemia,The biochemical approach to the classification of anemias-1,The biochemical approach to the classification of anemias-1,Biochemistry in transfusion medicine,Tissue banking and biochemistry. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course, the students will be able to: 1-Explain the relation of the structure of hemoglobin and its relation with anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explain the detailed structure of hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Explain the function and the importance of the hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3.Explain the synthesis of the hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4.Describe the normal types of hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2- Explain the abnormal types of hemoglobin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1.Explain the methods that are used to characterize abnormal hemoglobin types. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Explain hemogram method in a detailed way. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3.Describe hemoglobin electrophoresis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Desribe and classify hemoglobinopathies. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1.Explain sickle cell anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3.Describe hemoglobins with abnormal oxygen affinities. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4.Explain the thalassemia and classify. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4-Describe the tests used for anemia diagnosis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Explainthe details of hematocrit measurement. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2.Describes the method of erythrocyte calculation. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3.comprasion the anemia with hemoglobin measurement and erythrocyte index. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4.Describe the automatic complete blood cell count devices. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5-Classify the types of anemias. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1.Question the relation of morphological and classification of anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2.Questions the classification of anemias regarding their etiology. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3.Evaulate the classification of anemia in biochemical aspect. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.Compare the erythrocyte metabolism with anemias. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.1.Evaluate erythrocyte metabolism in biochemical aspect | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.2.Explain the importance of erythrocyte membrane proteins. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.3.Describes the porphyrias. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7-Evaluate iron metabolism in biochemical aspect. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7.1.Describe the iron-deficiency dependent anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7.2.Explain the iron in nutrition and its income. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7.3.Describe the absorption iron by erythrocytes and its transportation to bone marrow. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 8-Questions the relationship of cyanocobalamin (B12) and folic acid (B9) metabolism with anemia | 10, 11, 16, 19, 6, 9 | D, E |
| 8.1.Describes B12 deficiency anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 8.2.Explain the folic-acid deficiency dependent anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 9-Explainthe importance of biochmistry in transfusion medicine. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 10-Describe the relationshiop of biochemistry and tissue banking. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 10-Describe the relationshiop of biochemistry and tissue banking. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2. Question the variants of sickle cell anemia. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Hemogram | 1, 2, 3, 4, 5 |
| 2 | Hematopoiesis | 1, 2, 3, 4, 5 |
| 3 | Eritrocycye metabolism | 1, 2, 3, 4, 5 |
| 4 | Eritrocycte membrane proteins and its importance | 1, 2, 3, 4, 5 |
| 5 | Hemoglobin synthesis | 1, 2, 3, 4, 5 |
| 6 | Porfirias | 1, 2, 3, 4, 5 |
| 7 | Hemoglobin electrophoresis | 1, 2, 3, 4, 5 |
| 8 | HbAıc measurements | 1, 2, 3, 4, 5 |
| 9 | Iron metabolism | 1, 2, 3, 4, 5 |
| 10 | Cyanokobalamin (B12) and Folic acid (B9) metabolism and relation with anemia | 1, 2, 3, 4, 5 |
| 11 | The biochemical approach to the classification of anemias-1 | 1, 2, 3, 4, 5 |
| 12 | The biochemical approach to the classification of anemias-1 | 1, 2, 3, 4, 5 |
| 13 | Biochemistry in transfusion medicine | 1, 2, 3, 4, 5 |
| 14 | Tissue banking and biochemistry | 1, 2, 3, 4, 5 |
| Resources |
| Published books of Prof. Dr.Nesrin Emekli, Assoc. Prof. Dr. Türkan Yiğitbaşı |
| Henry Williams ve Wintrobe hematoloji Marks 831 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Defines macro and micromolecules in cell and body fluids at an advanced level. | ||||||
| 2 | Knows how to store and protect the material to be analyzed. | ||||||
| 3 | Knows how to identify molecules found in cells and body fluids. | ||||||
| 4 | Knows the principles of technologies to be used for routine and research purposes. | ||||||
| 5 | Knows how to evaluate the results of the study, interprets and questions. | ||||||
| 6 | Knows how to use field-specific tools and equipment | ||||||
| 7 | Knows how to access and interpret field-specific resources and information | ||||||
| 8 | Shares information with disciplines related to the field | ||||||
| 9 | Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals. | ||||||
| 10 | Solves a scientific and technical problem, knows where to get help. | ||||||
| 11 | Takes responsibility in joint scientific studies, contributes and works in harmony. | ||||||
| 12 | Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field. | ||||||
| 13 | Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially. | ||||||
| 14 | Can take part in management activities, evaluate the results obtained to improve quality | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |