Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOLOGY | - | Yearly | 33+0 | - | 2 |
| Course Program | Çarşamba 13:30-14:15 Çarşamba 14:30-15:15 Çarşamba 15:30-16:15 Çarşamba 16:30-17:15 Perşembe 10:00-10:45 Perşembe 11:00-11:45 Perşembe 12:00-12:45 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assoc.Prof. Ayşe Arzu ŞAKUL |
| Name of Lecturer(s) | Assoc.Prof. Ayşe Arzu ŞAKUL |
| Assistant(s) | |
| Aim | This course aims to understand the general pharmacokinetic, pharmacodynamic and pharmacogenetic properties of drugs and explain the mechanism of action of antimicrobial drugs and autacoids. |
| Course Content | This course contains; Introduction of Pharmacology- subbranches,Pharmaceutical Types of Drugs,Routes of Drug Administration,Drug Transmission from Membranes and Absorbtion,Drug Distribution ,Biotransformation of Drugs,Excretion of Drugs,Factors Modifying Drug Effects,Pharmacogenetics,Pharmacokinetics of Drugs,Pharmacodynamics of Drugs,Receptors and Drug-Receptor Interaction,Drug-Concentration-Effect Relationship,Mechanisms of Drug Action,Autacoids (Eicosanoids-Prostaglandines and other Autacoids),Autacoids (Histamine),Autacoids (Serotonin and Serotonin Agonist and Antagonists),Peptide Autacoids and Nitric Oxide,General Properties of Antimicrobial Chemotherapeutics,Penicillins, Beta-Lactamase Inhibitors,Cephalosporins,Other Beta-Lactam Antibiotics,Antimycobacterial Drugs,Narrow-Spectrum Antistaphylococcal and Antianaerobic Agents,Aminoglicosides,Sulfonamides, Co-Trimoxazole, Trimetoprim,Amphenicols, Tetracyclines,Fluoroquinolones,Macrolides. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explains general pharmacokinetic, pharmacodynamic and pharmacogenetic properties of drugs. | 16, 9 | A |
| Explains the mechanism of action, pharmacokinetics, pharmacodynamics, pharmacogenetic properties, toxic effects, drug interactions and clinical use of antimicrobial drugs. | 16, 9 | A |
| Explains the mechanism of action, pharmacokinetics, toxic effects, drug interactions and clinical use of autacoids. | 16, 9 | A |
| Evaluate drug use in the pregnancy population in terms of pharmacokinetics and pharmacodynamics. | 16, 9 | A |
| Evaluate drug use in the geriatric population in terms of pharmacokinetics and pharmacodynamics. | 16, 9 | A |
| Evaluate drug use in the pediatric population in terms of pharmacokinetics and pharmacodynamics. | 16, 9 | A |
| Analyzes pharmacokinetic interactions between drugs. | 16, 9 | A |
| Compare drug administration routes in terms of bioavailability. | 16, 9 | A |
| Evaluate antibiotic drug groups in terms of effectiveness and safety. |
| Teaching Methods: | 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction of Pharmacology- subbranches | Preparation for the previously given lecture note |
| 2 | Pharmaceutical Types of Drugs | Preparation for the previously given lecture note |
| 3 | Routes of Drug Administration | Preparation for the previously given lecture note |
| 4 | Drug Transmission from Membranes and Absorbtion | Preparation for the previously given lecture note |
| 5 | Drug Distribution | Preparation for the previously given lecture note |
| 6 | Biotransformation of Drugs | Preparation for the previously given lecture note |
| 7 | Excretion of Drugs | Preparation for the previously given lecture note |
| 8 | Factors Modifying Drug Effects | Preparation for the previously given lecture note |
| 9 | Pharmacogenetics | Preparation for the previously given lecture note |
| 10 | Pharmacokinetics of Drugs | Preparation for the previously given lecture note |
| 11 | Pharmacodynamics of Drugs | Preparation for the previously given lecture note |
| 12 | Receptors and Drug-Receptor Interaction | Preparation for the previously given lecture note |
| 13 | Drug-Concentration-Effect Relationship | Preparation for the previously given lecture note |
| 14 | Mechanisms of Drug Action | Preparation for the previously given lecture note |
| 15 | Autacoids (Eicosanoids-Prostaglandines and other Autacoids) | Preparation for the previously given lecture note |
| 16 | Autacoids (Histamine) | Preparation for the previously given lecture note |
| 17 | Autacoids (Serotonin and Serotonin Agonist and Antagonists) | Preparation for the previously given lecture note |
| 18 | Peptide Autacoids and Nitric Oxide | Preparation for the previously given lecture note |
| 19 | General Properties of Antimicrobial Chemotherapeutics | Preparation for the previously given lecture note |
| 20 | Penicillins, Beta-Lactamase Inhibitors | Preparation for the previously given lecture note |
| 21 | Cephalosporins | Preparation for the previously given lecture note |
| 22 | Other Beta-Lactam Antibiotics | Preparation for the previously given lecture note |
| 23 | Antimycobacterial Drugs | Preparation for the previously given lecture note |
| 24 | Narrow-Spectrum Antistaphylococcal and Antianaerobic Agents | Preparation for the previously given lecture note |
| 25 | Aminoglicosides | Preparation for the previously given lecture note |
| 26 | Sulfonamides, Co-Trimoxazole, Trimetoprim | Preparation for the previously given lecture note |
| 27 | Amphenicols, Tetracyclines | Preparation for the previously given lecture note |
| 28 | Fluoroquinolones | Preparation for the previously given lecture note |
| 29 | Macrolides | Preparation for the previously given lecture note |
| Resources |
| Goodman & Gilman’nın Tedavinin Farmakolojik Temeli - / Laurence L.Brunton - John S.Lazo - Keith L.Parker Nobel Tıp Kitapevleri Yayınları,İstanbul, 2008 Katzung & Trevor's Pharmacology Examination and Board Review: Eighth Edition McGraw-Hill Medical Publishing USA, 2008. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji 13. Baskı - Prof.Dr. Oğuz Kayaalp, Pelikan Yayınları, 2012. Sağlık Bilimleri için Farmakoloji- Dr. Öğr. Ü. A. Arzu SAYIN ŞAKUL, İstanbul Tıp Yayınevi-2021 |
| Lecture notes will be given to the students. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | X | |||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | X | |||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | X | |||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | X | |||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | X | |||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | X | |||||
| 21 | Has adequate awareness on occupational health and safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 2 | 1 | 2 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 4 | 3 | 12 | |||
| General Exam | 6 | 3 | 18 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 60 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(60/30) | 2 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACOLOGY | - | Yearly | 33+0 | - | 2 |
| Course Program | Çarşamba 13:30-14:15 Çarşamba 14:30-15:15 Çarşamba 15:30-16:15 Çarşamba 16:30-17:15 Perşembe 10:00-10:45 Perşembe 11:00-11:45 Perşembe 12:00-12:45 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assoc.Prof. Ayşe Arzu ŞAKUL |
| Name of Lecturer(s) | Assoc.Prof. Ayşe Arzu ŞAKUL |
| Assistant(s) | |
| Aim | This course aims to understand the general pharmacokinetic, pharmacodynamic and pharmacogenetic properties of drugs and explain the mechanism of action of antimicrobial drugs and autacoids. |
| Course Content | This course contains; Introduction of Pharmacology- subbranches,Pharmaceutical Types of Drugs,Routes of Drug Administration,Drug Transmission from Membranes and Absorbtion,Drug Distribution ,Biotransformation of Drugs,Excretion of Drugs,Factors Modifying Drug Effects,Pharmacogenetics,Pharmacokinetics of Drugs,Pharmacodynamics of Drugs,Receptors and Drug-Receptor Interaction,Drug-Concentration-Effect Relationship,Mechanisms of Drug Action,Autacoids (Eicosanoids-Prostaglandines and other Autacoids),Autacoids (Histamine),Autacoids (Serotonin and Serotonin Agonist and Antagonists),Peptide Autacoids and Nitric Oxide,General Properties of Antimicrobial Chemotherapeutics,Penicillins, Beta-Lactamase Inhibitors,Cephalosporins,Other Beta-Lactam Antibiotics,Antimycobacterial Drugs,Narrow-Spectrum Antistaphylococcal and Antianaerobic Agents,Aminoglicosides,Sulfonamides, Co-Trimoxazole, Trimetoprim,Amphenicols, Tetracyclines,Fluoroquinolones,Macrolides. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explains general pharmacokinetic, pharmacodynamic and pharmacogenetic properties of drugs. | 16, 9 | A |
| Explains the mechanism of action, pharmacokinetics, pharmacodynamics, pharmacogenetic properties, toxic effects, drug interactions and clinical use of antimicrobial drugs. | 16, 9 | A |
| Explains the mechanism of action, pharmacokinetics, toxic effects, drug interactions and clinical use of autacoids. | 16, 9 | A |
| Evaluate drug use in the pregnancy population in terms of pharmacokinetics and pharmacodynamics. | 16, 9 | A |
| Evaluate drug use in the geriatric population in terms of pharmacokinetics and pharmacodynamics. | 16, 9 | A |
| Evaluate drug use in the pediatric population in terms of pharmacokinetics and pharmacodynamics. | 16, 9 | A |
| Analyzes pharmacokinetic interactions between drugs. | 16, 9 | A |
| Compare drug administration routes in terms of bioavailability. | 16, 9 | A |
| Evaluate antibiotic drug groups in terms of effectiveness and safety. |
| Teaching Methods: | 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction of Pharmacology- subbranches | Preparation for the previously given lecture note |
| 2 | Pharmaceutical Types of Drugs | Preparation for the previously given lecture note |
| 3 | Routes of Drug Administration | Preparation for the previously given lecture note |
| 4 | Drug Transmission from Membranes and Absorbtion | Preparation for the previously given lecture note |
| 5 | Drug Distribution | Preparation for the previously given lecture note |
| 6 | Biotransformation of Drugs | Preparation for the previously given lecture note |
| 7 | Excretion of Drugs | Preparation for the previously given lecture note |
| 8 | Factors Modifying Drug Effects | Preparation for the previously given lecture note |
| 9 | Pharmacogenetics | Preparation for the previously given lecture note |
| 10 | Pharmacokinetics of Drugs | Preparation for the previously given lecture note |
| 11 | Pharmacodynamics of Drugs | Preparation for the previously given lecture note |
| 12 | Receptors and Drug-Receptor Interaction | Preparation for the previously given lecture note |
| 13 | Drug-Concentration-Effect Relationship | Preparation for the previously given lecture note |
| 14 | Mechanisms of Drug Action | Preparation for the previously given lecture note |
| 15 | Autacoids (Eicosanoids-Prostaglandines and other Autacoids) | Preparation for the previously given lecture note |
| 16 | Autacoids (Histamine) | Preparation for the previously given lecture note |
| 17 | Autacoids (Serotonin and Serotonin Agonist and Antagonists) | Preparation for the previously given lecture note |
| 18 | Peptide Autacoids and Nitric Oxide | Preparation for the previously given lecture note |
| 19 | General Properties of Antimicrobial Chemotherapeutics | Preparation for the previously given lecture note |
| 20 | Penicillins, Beta-Lactamase Inhibitors | Preparation for the previously given lecture note |
| 21 | Cephalosporins | Preparation for the previously given lecture note |
| 22 | Other Beta-Lactam Antibiotics | Preparation for the previously given lecture note |
| 23 | Antimycobacterial Drugs | Preparation for the previously given lecture note |
| 24 | Narrow-Spectrum Antistaphylococcal and Antianaerobic Agents | Preparation for the previously given lecture note |
| 25 | Aminoglicosides | Preparation for the previously given lecture note |
| 26 | Sulfonamides, Co-Trimoxazole, Trimetoprim | Preparation for the previously given lecture note |
| 27 | Amphenicols, Tetracyclines | Preparation for the previously given lecture note |
| 28 | Fluoroquinolones | Preparation for the previously given lecture note |
| 29 | Macrolides | Preparation for the previously given lecture note |
| Resources |
| Goodman & Gilman’nın Tedavinin Farmakolojik Temeli - / Laurence L.Brunton - John S.Lazo - Keith L.Parker Nobel Tıp Kitapevleri Yayınları,İstanbul, 2008 Katzung & Trevor's Pharmacology Examination and Board Review: Eighth Edition McGraw-Hill Medical Publishing USA, 2008. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji 13. Baskı - Prof.Dr. Oğuz Kayaalp, Pelikan Yayınları, 2012. Sağlık Bilimleri için Farmakoloji- Dr. Öğr. Ü. A. Arzu SAYIN ŞAKUL, İstanbul Tıp Yayınevi-2021 |
| Lecture notes will be given to the students. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | X | |||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | X | |||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | X | |||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | X | |||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | X | |||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | X | |||||
| 21 | Has adequate awareness on occupational health and safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |