Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| Endocrine & Nutrition | 13. Module | Fall Semester | 75+22 | - | 7 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee |
| Course Coordinator | |
| Name of Lecturer(s) | |
| Assistant(s) | Prof.Dr. Bahar MÜEZZİNOĞLU, Prof.Dr. Sergülen DERVİŞOĞLU, Öğr.Gör. Rukiye Nilgün ERDOĞAN Dr.Öğr.Üye. Çağlar MACİT, Prof.Dr. Recep Serdar ALPAN, Doç.Dr. Mustafa GÜZEL Prof.Dr. Ayhan TAŞTEKİN, Prof.Dr. Seniye Sema ANAK, Prof.Dr. Sedat OKTEM, Prof.Dr. Abdullah ERDEM, Prof.Dr. Celal AKDENİZ, Prof.Dr. Cihangir AKGÜN, Prof.Dr. Gökhan BAYSOY, Doç.Dr. Öznur KÜÇÜK, Prof.Dr. İlke ÖZAHİ İPEK, Doç.Dr. Yasemin TOPÇU, Doç.Dr. Nalan KARABAYIR, Dr.Öğr.Üye. Remzi ERKESİM, Dr.Öğr.Üye. Yöntem YAMAN, Dr.Öğr.Üye. Hülya BİLGEN, Dr.Öğr.Üye. Sevgki CHODZA OGLOU, Prof.Dr. Zeynep ATAY Doç.Dr. Mesut YILMAZ, Dr.Öğr.Üye. Özlem GÜVEN, Dr.Öğr.Üye. Canan SEVER, Dr.Öğr.Üye. Betül GİRAY, Dr.Öğr.Üye. Selda AYDIN, Dr.Öğr.Üye. Okan DERİN Prof.Dr. Özcan YILDIZ, Doç.Dr. Ömür Gökmen SEVİNDİK, Dr.Öğr.Üye. Hüseyin Saffet BEKÖZ,Dr.Öğr.Üye. Ali Timuçin ATAYOĞLU, Prof.Dr. Vedat GÖRAL, Doç.Dr. Meryem CAN Prof.Dr. Tamer ATASEVER, Prof.Dr. Ayşenur CİLA, Prof.Dr. Erol AKGÜL, Prof.Dr. Cengiz EROL, Dr.Öğr.Üye. Tansel ÇAKIR Prof.Dr. Müjgan ÇALIŞKAN EVREN, Prof.Dr. Mustafa ÖNCEL, Prof.Dr. Fazlı Cem GEZEN, Dr.Öğr.Üye. Pelin BASIM, |
| Aim | The aim of this committee is to provide information about the normal structure of the endocrine system, its functions, etiopathogenesis of diseases related to this system, symptoms, basic clinical and laboratory findings, diagnostic methods and drugs used in their treatment. |
| Course Content | This course contains; Pathology of Thyroid disease, Basics of thyroid function testsclinical features and treatment of hypothyroidism, thyroiditis, iodine deficiency, hyperthyroidism, thyroid cancer. Radiological (Ultrasound and scan) features of thyroiditis, thyroid nodules, Graves disease, toxic and non-toxic nodular disease. ,Macroscopic and microscopic features of pituitary disease, interpretation of anterior and posterior pituitary functions, review of pitruitary hormone changes and correlation with hypothalamic hormones and end hormones, concept of macroprolactinemia, Stalk effect and hook effects for interpretation of prolactin elevation, clinicali lab and MR features of acromegaly, Cushing disease, TSH secreting tumors and prolactinoma. Diagnosis , differential diagnosis of pituitary tumors. Radiological features of Pituitary tumors, empty sella, hypophysitis,Hypopituitarism, diabetes incipitus, clinical features, treatment,Macroscopic and microscopic anatomic changes in various parathyroid disease, Approach to hypercalcemia and hypocalcemia. Clinical, lab and radiological features of primary hyperparathyroidism, osteoporosis, hypoparathyroidism, end stage renal disease. Clinical and lab features of MEN syndromes. Interpretation of bone mineral density, Management of vitamin D deficincy,Clinical features of type 1 and type 2 diabetes, the importance of diabetes... diagnosİs of diabetes mellitus type 1, type 2 gestational diabetes, the importance of glycosylated hemoglobin and oral glucose tolerance test. The macroscopic and microscopic anatomic features of diabetes, autoimmune development, resistance to insulin, polycystic ovary syndrome, metabolic syndrome. Acute and chronic complications of type diabetes- prevention and treatment. Prevention or Cardiovascular complications in type 2 diabetes. The pharmacokinetic features of insulins, how to establish an insulin treatment. The medications used for type 2 diabetes: treatment effects and adverse effects. The treatment algorithm in type 2 diabetes. Hypoglycemia, prevention and treatment. Non-diabetic hypoglycemia,Macroscopic and microscopic anatomic changes in adrenal disease. Review of hypothalamus, pituitary and adrenal gland axis. Symptoms of adrenal insufficiency, clinical features, laboratory findings, diagnosis and treatment. Review of mineralocorticoid and glucocorticoid actions of steroids. Cushing’s syndrome: screening, diagnosis, identification of the hypersecretion site. Secondary hypertension: primary hyperaldosteronism, pheochromocytoma,Pathology of Pituitary Diseases,Pathology of Thyroid Diseases-1-,Pathology of Parathyroid Diseases and MEN Syndromes ,Pathology of Adrenal Gland Diseases (1) ,Pathology of Adrenal Gland Diseases (2) ,Pathology of Endocrine Pancreatic Diseases (1),Pathology of Endocrine Pancreatic Diseases (2),LAB-Team Based Learning ,History, Physical Examination and Diagnostic Methods in Endocrine Diseases 1-,History, Physical Examination and Diagnostic Methods in Endocrine Diseases 2-,Introduction to Endocrinology Anterior Pituitary and Hypothalamus,Posterior Pituitary and Diabetes Insipidus,Congenital Metabolism Diseases History, Physical Examination and Diagnostic Methods ,Bone Health and Diseases in Children,History, Physical Examination and Diagnostic Methods in Congenital Metabolic Diseases-,Normal Puberty,Type 1 Diabetes Mellitus,Medical Pharmacology- Drugs for treatment of hypothyroid disorders,Medical Pharmacology- Drugs for treatment of hyperthyroid disorders,Medical Pharmacology- Drugs for treatment of diabetes mellitus 1,Medical Pharmacology- Drugs for treatment of diabetes mellitus 2,Medical Pharmacology- Drugs for treatment of diabetes mellitus 3,Medical Pharmacology- Drugs for treatment of osteoporosis 1,Tıbbi Farmakoloji - Osteoporoz tedavisine yönelik ilaçlar 2-,Medical Pharmacology- Drugs for treatment of pituitary disorders,Medical Pharmacology- Adrenal steroids ,Medical Pharmacology- Questions, answers and discussion ,Public Health -Community Nutrition,Public Health -Nutritional Epidemiology,Public Health -Epidemiology of Type 2 Diabetes,Public Health -School Health,Scientific Research-Cross-sectional Studies,Microbiology-Introduction to mycology,Microbiology -Superficial mycoses,Microbiology -LAB (1-2-3)-Clinically important fungi and preparation examination,Radiology-Nuclear Medicine-Nuclear Medicine Applications and Treatments in Endocrine System ,Internal Medicine – Hypothalamic -Pituitary Disorders (2),Internal Medicine – Diseases of Posterior Pituitary,Adrenal Diseases ,Endocrine hypertension,Lipid Disorders,Diseases of calcium metabolism 1-2,Osteoporosis,Hirsutism and Polycystic Ovary Syndrome,Cross-sectional Studies . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Microbiological features of endocrine system disease | ||
| 1. Defines the anatomical structures of the endocrine system. particularly the relation of hypothalamus, pituitary and Target and organs as well as hormonal secretion patterns including positive and negative feedback, stalk and hook effects to explain prolactin elevations | 37, 9 | A |
| 2. At the end of this committee, students list the etiopathogenesis, clinic, laboratory signs and histopathological findings of endocrine system diseases.Specifically includes Hypothyroidism, hyperhyroidism, thyroid nodules and thyroid cancers, thyroiditis, iodine deficiency, pituitary insufficiency, Cushing disease, prolactinoma, acromegaly, approach to pituitary tumors, İmaging modalities to diagnose pityitary disease, diabetes insipidus, hypercalcemia and hypocalcemia, osteoporosis, adrenal insufficiency, differentiation of primary versus secondary adrenal insufficiency, Cushing syndrome differential diagnosis of primary versus secondary or tertiary. Adrenal incidentaloma, hypoglycemia, basics of nutrition and heatly eating, obesity, endocrine hypertension. Endocrine basics of development from childhood to puberty, puberty precox, delayed puberty, endocrine hypertension, pheochromocytoma, Primary hyperaldosteronism | ||
| 3. Be able to define imaging methods used for endocrine system. | ||
| 4. Be able to list the treatment methods used in endocrine system diseases.Specifically pharmacokinetic features of insulins nd oral antihyperglycemic agents, treatment algorhytms for Type 2 diabetes, farmacokinetic features of corticosteroids, Thyroid hormones, antithyroid hormones, medications used for treatment of acromegaly, Cushing disease, hypogonadism, contraseption, menopause, osteoporisis, | ||
| 5. Be able to list the effects of drugs used in the treatment of endocrine system diseases, their mechanism of action, pharmacokinetics, side effects and drug interactions. |
| Teaching Methods: | 37: Computer-Internet Supported Instruction, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Pathology of Thyroid disease, Basics of thyroid function testsclinical features and treatment of hypothyroidism, thyroiditis, iodine deficiency, hyperthyroidism, thyroid cancer. Radiological (Ultrasound and scan) features of thyroiditis, thyroid nodules, Graves disease, toxic and non-toxic nodular disease. | none |
| 2 | Macroscopic and microscopic features of pituitary disease, interpretation of anterior and posterior pituitary functions, review of pitruitary hormone changes and correlation with hypothalamic hormones and end hormones, concept of macroprolactinemia, Stalk effect and hook effects for interpretation of prolactin elevation, clinicali lab and MR features of acromegaly, Cushing disease, TSH secreting tumors and prolactinoma. Diagnosis , differential diagnosis of pituitary tumors. Radiological features of Pituitary tumors, empty sella, hypophysitis,Hypopituitarism, diabetes incipitus, clinical features, treatment | none |
| 3 | Macroscopic and microscopic anatomic changes in various parathyroid disease, Approach to hypercalcemia and hypocalcemia. Clinical, lab and radiological features of primary hyperparathyroidism, osteoporosis, hypoparathyroidism, end stage renal disease. Clinical and lab features of MEN syndromes. Interpretation of bone mineral density, Management of vitamin D deficincy | none |
| 4 | Clinical features of type 1 and type 2 diabetes, the importance of diabetes... diagnosİs of diabetes mellitus type 1, type 2 gestational diabetes, the importance of glycosylated hemoglobin and oral glucose tolerance test. The macroscopic and microscopic anatomic features of diabetes, autoimmune development, resistance to insulin, polycystic ovary syndrome, metabolic syndrome. Acute and chronic complications of type diabetes- prevention and treatment. Prevention or Cardiovascular complications in type 2 diabetes. The pharmacokinetic features of insulins, how to establish an insulin treatment. The medications used for type 2 diabetes: treatment effects and adverse effects. The treatment algorithm in type 2 diabetes. Hypoglycemia, prevention and treatment. Non-diabetic hypoglycemia | NONE |
| 5 | Macroscopic and microscopic anatomic changes in adrenal disease. Review of hypothalamus, pituitary and adrenal gland axis. Symptoms of adrenal insufficiency, clinical features, laboratory findings, diagnosis and treatment. Review of mineralocorticoid and glucocorticoid actions of steroids. Cushing’s syndrome: screening, diagnosis, identification of the hypersecretion site. Secondary hypertension: primary hyperaldosteronism, pheochromocytoma | none |
| 7 | Pathology of Pituitary Diseases | none |
| 8 | Pathology of Thyroid Diseases-1- | none |
| 9 | Pathology of Parathyroid Diseases and MEN Syndromes | none |
| 10 | Pathology of Adrenal Gland Diseases (1) | none |
| 11 | Pathology of Adrenal Gland Diseases (2) | none |
| 12 | Pathology of Endocrine Pancreatic Diseases (1) | none |
| 13 | Pathology of Endocrine Pancreatic Diseases (2) | none |
| 14 | LAB-Team Based Learning | |
| 15 | History, Physical Examination and Diagnostic Methods in Endocrine Diseases 1- | none |
| 16 | History, Physical Examination and Diagnostic Methods in Endocrine Diseases 2- | none |
| 17 | Introduction to Endocrinology Anterior Pituitary and Hypothalamus | none |
| 18 | Posterior Pituitary and Diabetes Insipidus | none |
| 18 | Congenital Metabolism Diseases History, Physical Examination and Diagnostic Methods | none |
| 19 | Bone Health and Diseases in Children | none |
| 20 | History, Physical Examination and Diagnostic Methods in Congenital Metabolic Diseases- | none |
| 21 | Normal Puberty | none |
| 22 | Type 1 Diabetes Mellitus | none |
| 23 | Medical Pharmacology- Drugs for treatment of hypothyroid disorders | none |
| 24 | Medical Pharmacology- Drugs for treatment of hyperthyroid disorders | none |
| 25 | Medical Pharmacology- Drugs for treatment of diabetes mellitus 1 | none |
| 26 | Medical Pharmacology- Drugs for treatment of diabetes mellitus 2 | none |
| 27 | Medical Pharmacology- Drugs for treatment of diabetes mellitus 3 | none |
| 28 | Medical Pharmacology- Drugs for treatment of osteoporosis 1 | none |
| 29 | Tıbbi Farmakoloji - Osteoporoz tedavisine yönelik ilaçlar 2- | none |
| 30 | Medical Pharmacology- Drugs for treatment of pituitary disorders | none |
| 31 | Medical Pharmacology- Adrenal steroids | none |
| 32 | Medical Pharmacology- Questions, answers and discussion | none |
| 33 | Public Health -Community Nutrition | none |
| 34 | Public Health -Nutritional Epidemiology | none |
| 35 | Public Health -Epidemiology of Type 2 Diabetes | none |
| 36 | Public Health -School Health | none |
| 37 | Scientific Research-Cross-sectional Studies | none |
| 38 | Microbiology-Introduction to mycology | none |
| 39 | Microbiology -Superficial mycoses | none |
| 40 | Microbiology -LAB (1-2-3)-Clinically important fungi and preparation examination | |
| 41 | Radiology-Nuclear Medicine-Nuclear Medicine Applications and Treatments in Endocrine System | none |
| 42 | Internal Medicine – Hypothalamic -Pituitary Disorders (2) | none |
| 43 | Internal Medicine – Diseases of Posterior Pituitary | none |
| 44 | Adrenal Diseases | none |
| 45 | Endocrine hypertension | none |
| 46 | Lipid Disorders | none |
| 47 | Diseases of calcium metabolism 1-2 | none |
| 48 | Osteoporosis | none |
| 49 | Hirsutism and Polycystic Ovary Syndrome | none |
| 50 | Cross-sectional Studies |
| Resources |
| Patology: Vinay Kumar, Abul K. Abbas, Nelson Fausto, Richard Mitchell: Robbins Basic Pathology. 10 th ed. Saunders/Elsevier Edward C. Klatt: Robbins and Cotran Atlas of Pathology. 2nd ed. Saunders. online websites( Pathology outlines vb) lecture notes:ppt Pharmacology : 1.Kayaalp, SO: Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara. 2.Hardman JG, Limbird LE, Eds.: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, New York. 3.Katzung & Trevor: Farmakoloji, Ankara. Microbiyoloji: Microbiology: An Introduction (11th Edition), Gerard J. Tortora Internal medicine: Harrison Internal Medicine-İç hastalıkları Ders kitabı Uptodate database Greenspan : basiz and clinical endocrinology presentation notes-ppt Surgery: : schwartz principles of general surgery 10th edition Radiology and Pediatrics: Presentation notes-PPT slides |
| none |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | ||||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | ||||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | ||||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | ||||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | ||||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | ||||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | ||||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | ||||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | ||||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | ||||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | ||||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | ||||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | ||||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | ||||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 65 | 1 | 65 | |||
| Guided Problem Solving | 10 | 1 | 10 | |||
| Resolution of Homework Problems and Submission as a Report | 3 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 12 | 2 | 24 | |||
| General Exam | 40 | 3 | 120 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 219 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(219/30) | 7 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| Endocrine & Nutrition | 13. Module | Fall Semester | 75+22 | - | 7 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee |
| Course Coordinator | |
| Name of Lecturer(s) | |
| Assistant(s) | Prof.Dr. Bahar MÜEZZİNOĞLU, Prof.Dr. Sergülen DERVİŞOĞLU, Öğr.Gör. Rukiye Nilgün ERDOĞAN Dr.Öğr.Üye. Çağlar MACİT, Prof.Dr. Recep Serdar ALPAN, Doç.Dr. Mustafa GÜZEL Prof.Dr. Ayhan TAŞTEKİN, Prof.Dr. Seniye Sema ANAK, Prof.Dr. Sedat OKTEM, Prof.Dr. Abdullah ERDEM, Prof.Dr. Celal AKDENİZ, Prof.Dr. Cihangir AKGÜN, Prof.Dr. Gökhan BAYSOY, Doç.Dr. Öznur KÜÇÜK, Prof.Dr. İlke ÖZAHİ İPEK, Doç.Dr. Yasemin TOPÇU, Doç.Dr. Nalan KARABAYIR, Dr.Öğr.Üye. Remzi ERKESİM, Dr.Öğr.Üye. Yöntem YAMAN, Dr.Öğr.Üye. Hülya BİLGEN, Dr.Öğr.Üye. Sevgki CHODZA OGLOU, Prof.Dr. Zeynep ATAY Doç.Dr. Mesut YILMAZ, Dr.Öğr.Üye. Özlem GÜVEN, Dr.Öğr.Üye. Canan SEVER, Dr.Öğr.Üye. Betül GİRAY, Dr.Öğr.Üye. Selda AYDIN, Dr.Öğr.Üye. Okan DERİN Prof.Dr. Özcan YILDIZ, Doç.Dr. Ömür Gökmen SEVİNDİK, Dr.Öğr.Üye. Hüseyin Saffet BEKÖZ,Dr.Öğr.Üye. Ali Timuçin ATAYOĞLU, Prof.Dr. Vedat GÖRAL, Doç.Dr. Meryem CAN Prof.Dr. Tamer ATASEVER, Prof.Dr. Ayşenur CİLA, Prof.Dr. Erol AKGÜL, Prof.Dr. Cengiz EROL, Dr.Öğr.Üye. Tansel ÇAKIR Prof.Dr. Müjgan ÇALIŞKAN EVREN, Prof.Dr. Mustafa ÖNCEL, Prof.Dr. Fazlı Cem GEZEN, Dr.Öğr.Üye. Pelin BASIM, |
| Aim | The aim of this committee is to provide information about the normal structure of the endocrine system, its functions, etiopathogenesis of diseases related to this system, symptoms, basic clinical and laboratory findings, diagnostic methods and drugs used in their treatment. |
| Course Content | This course contains; Pathology of Thyroid disease, Basics of thyroid function testsclinical features and treatment of hypothyroidism, thyroiditis, iodine deficiency, hyperthyroidism, thyroid cancer. Radiological (Ultrasound and scan) features of thyroiditis, thyroid nodules, Graves disease, toxic and non-toxic nodular disease. ,Macroscopic and microscopic features of pituitary disease, interpretation of anterior and posterior pituitary functions, review of pitruitary hormone changes and correlation with hypothalamic hormones and end hormones, concept of macroprolactinemia, Stalk effect and hook effects for interpretation of prolactin elevation, clinicali lab and MR features of acromegaly, Cushing disease, TSH secreting tumors and prolactinoma. Diagnosis , differential diagnosis of pituitary tumors. Radiological features of Pituitary tumors, empty sella, hypophysitis,Hypopituitarism, diabetes incipitus, clinical features, treatment,Macroscopic and microscopic anatomic changes in various parathyroid disease, Approach to hypercalcemia and hypocalcemia. Clinical, lab and radiological features of primary hyperparathyroidism, osteoporosis, hypoparathyroidism, end stage renal disease. Clinical and lab features of MEN syndromes. Interpretation of bone mineral density, Management of vitamin D deficincy,Clinical features of type 1 and type 2 diabetes, the importance of diabetes... diagnosİs of diabetes mellitus type 1, type 2 gestational diabetes, the importance of glycosylated hemoglobin and oral glucose tolerance test. The macroscopic and microscopic anatomic features of diabetes, autoimmune development, resistance to insulin, polycystic ovary syndrome, metabolic syndrome. Acute and chronic complications of type diabetes- prevention and treatment. Prevention or Cardiovascular complications in type 2 diabetes. The pharmacokinetic features of insulins, how to establish an insulin treatment. The medications used for type 2 diabetes: treatment effects and adverse effects. The treatment algorithm in type 2 diabetes. Hypoglycemia, prevention and treatment. Non-diabetic hypoglycemia,Macroscopic and microscopic anatomic changes in adrenal disease. Review of hypothalamus, pituitary and adrenal gland axis. Symptoms of adrenal insufficiency, clinical features, laboratory findings, diagnosis and treatment. Review of mineralocorticoid and glucocorticoid actions of steroids. Cushing’s syndrome: screening, diagnosis, identification of the hypersecretion site. Secondary hypertension: primary hyperaldosteronism, pheochromocytoma,Pathology of Pituitary Diseases,Pathology of Thyroid Diseases-1-,Pathology of Parathyroid Diseases and MEN Syndromes ,Pathology of Adrenal Gland Diseases (1) ,Pathology of Adrenal Gland Diseases (2) ,Pathology of Endocrine Pancreatic Diseases (1),Pathology of Endocrine Pancreatic Diseases (2),LAB-Team Based Learning ,History, Physical Examination and Diagnostic Methods in Endocrine Diseases 1-,History, Physical Examination and Diagnostic Methods in Endocrine Diseases 2-,Introduction to Endocrinology Anterior Pituitary and Hypothalamus,Posterior Pituitary and Diabetes Insipidus,Congenital Metabolism Diseases History, Physical Examination and Diagnostic Methods ,Bone Health and Diseases in Children,History, Physical Examination and Diagnostic Methods in Congenital Metabolic Diseases-,Normal Puberty,Type 1 Diabetes Mellitus,Medical Pharmacology- Drugs for treatment of hypothyroid disorders,Medical Pharmacology- Drugs for treatment of hyperthyroid disorders,Medical Pharmacology- Drugs for treatment of diabetes mellitus 1,Medical Pharmacology- Drugs for treatment of diabetes mellitus 2,Medical Pharmacology- Drugs for treatment of diabetes mellitus 3,Medical Pharmacology- Drugs for treatment of osteoporosis 1,Tıbbi Farmakoloji - Osteoporoz tedavisine yönelik ilaçlar 2-,Medical Pharmacology- Drugs for treatment of pituitary disorders,Medical Pharmacology- Adrenal steroids ,Medical Pharmacology- Questions, answers and discussion ,Public Health -Community Nutrition,Public Health -Nutritional Epidemiology,Public Health -Epidemiology of Type 2 Diabetes,Public Health -School Health,Scientific Research-Cross-sectional Studies,Microbiology-Introduction to mycology,Microbiology -Superficial mycoses,Microbiology -LAB (1-2-3)-Clinically important fungi and preparation examination,Radiology-Nuclear Medicine-Nuclear Medicine Applications and Treatments in Endocrine System ,Internal Medicine – Hypothalamic -Pituitary Disorders (2),Internal Medicine – Diseases of Posterior Pituitary,Adrenal Diseases ,Endocrine hypertension,Lipid Disorders,Diseases of calcium metabolism 1-2,Osteoporosis,Hirsutism and Polycystic Ovary Syndrome,Cross-sectional Studies . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Microbiological features of endocrine system disease | ||
| 1. Defines the anatomical structures of the endocrine system. particularly the relation of hypothalamus, pituitary and Target and organs as well as hormonal secretion patterns including positive and negative feedback, stalk and hook effects to explain prolactin elevations | 37, 9 | A |
| 2. At the end of this committee, students list the etiopathogenesis, clinic, laboratory signs and histopathological findings of endocrine system diseases.Specifically includes Hypothyroidism, hyperhyroidism, thyroid nodules and thyroid cancers, thyroiditis, iodine deficiency, pituitary insufficiency, Cushing disease, prolactinoma, acromegaly, approach to pituitary tumors, İmaging modalities to diagnose pityitary disease, diabetes insipidus, hypercalcemia and hypocalcemia, osteoporosis, adrenal insufficiency, differentiation of primary versus secondary adrenal insufficiency, Cushing syndrome differential diagnosis of primary versus secondary or tertiary. Adrenal incidentaloma, hypoglycemia, basics of nutrition and heatly eating, obesity, endocrine hypertension. Endocrine basics of development from childhood to puberty, puberty precox, delayed puberty, endocrine hypertension, pheochromocytoma, Primary hyperaldosteronism | ||
| 3. Be able to define imaging methods used for endocrine system. | ||
| 4. Be able to list the treatment methods used in endocrine system diseases.Specifically pharmacokinetic features of insulins nd oral antihyperglycemic agents, treatment algorhytms for Type 2 diabetes, farmacokinetic features of corticosteroids, Thyroid hormones, antithyroid hormones, medications used for treatment of acromegaly, Cushing disease, hypogonadism, contraseption, menopause, osteoporisis, | ||
| 5. Be able to list the effects of drugs used in the treatment of endocrine system diseases, their mechanism of action, pharmacokinetics, side effects and drug interactions. |
| Teaching Methods: | 37: Computer-Internet Supported Instruction, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Pathology of Thyroid disease, Basics of thyroid function testsclinical features and treatment of hypothyroidism, thyroiditis, iodine deficiency, hyperthyroidism, thyroid cancer. Radiological (Ultrasound and scan) features of thyroiditis, thyroid nodules, Graves disease, toxic and non-toxic nodular disease. | none |
| 2 | Macroscopic and microscopic features of pituitary disease, interpretation of anterior and posterior pituitary functions, review of pitruitary hormone changes and correlation with hypothalamic hormones and end hormones, concept of macroprolactinemia, Stalk effect and hook effects for interpretation of prolactin elevation, clinicali lab and MR features of acromegaly, Cushing disease, TSH secreting tumors and prolactinoma. Diagnosis , differential diagnosis of pituitary tumors. Radiological features of Pituitary tumors, empty sella, hypophysitis,Hypopituitarism, diabetes incipitus, clinical features, treatment | none |
| 3 | Macroscopic and microscopic anatomic changes in various parathyroid disease, Approach to hypercalcemia and hypocalcemia. Clinical, lab and radiological features of primary hyperparathyroidism, osteoporosis, hypoparathyroidism, end stage renal disease. Clinical and lab features of MEN syndromes. Interpretation of bone mineral density, Management of vitamin D deficincy | none |
| 4 | Clinical features of type 1 and type 2 diabetes, the importance of diabetes... diagnosİs of diabetes mellitus type 1, type 2 gestational diabetes, the importance of glycosylated hemoglobin and oral glucose tolerance test. The macroscopic and microscopic anatomic features of diabetes, autoimmune development, resistance to insulin, polycystic ovary syndrome, metabolic syndrome. Acute and chronic complications of type diabetes- prevention and treatment. Prevention or Cardiovascular complications in type 2 diabetes. The pharmacokinetic features of insulins, how to establish an insulin treatment. The medications used for type 2 diabetes: treatment effects and adverse effects. The treatment algorithm in type 2 diabetes. Hypoglycemia, prevention and treatment. Non-diabetic hypoglycemia | NONE |
| 5 | Macroscopic and microscopic anatomic changes in adrenal disease. Review of hypothalamus, pituitary and adrenal gland axis. Symptoms of adrenal insufficiency, clinical features, laboratory findings, diagnosis and treatment. Review of mineralocorticoid and glucocorticoid actions of steroids. Cushing’s syndrome: screening, diagnosis, identification of the hypersecretion site. Secondary hypertension: primary hyperaldosteronism, pheochromocytoma | none |
| 7 | Pathology of Pituitary Diseases | none |
| 8 | Pathology of Thyroid Diseases-1- | none |
| 9 | Pathology of Parathyroid Diseases and MEN Syndromes | none |
| 10 | Pathology of Adrenal Gland Diseases (1) | none |
| 11 | Pathology of Adrenal Gland Diseases (2) | none |
| 12 | Pathology of Endocrine Pancreatic Diseases (1) | none |
| 13 | Pathology of Endocrine Pancreatic Diseases (2) | none |
| 14 | LAB-Team Based Learning | |
| 15 | History, Physical Examination and Diagnostic Methods in Endocrine Diseases 1- | none |
| 16 | History, Physical Examination and Diagnostic Methods in Endocrine Diseases 2- | none |
| 17 | Introduction to Endocrinology Anterior Pituitary and Hypothalamus | none |
| 18 | Posterior Pituitary and Diabetes Insipidus | none |
| 18 | Congenital Metabolism Diseases History, Physical Examination and Diagnostic Methods | none |
| 19 | Bone Health and Diseases in Children | none |
| 20 | History, Physical Examination and Diagnostic Methods in Congenital Metabolic Diseases- | none |
| 21 | Normal Puberty | none |
| 22 | Type 1 Diabetes Mellitus | none |
| 23 | Medical Pharmacology- Drugs for treatment of hypothyroid disorders | none |
| 24 | Medical Pharmacology- Drugs for treatment of hyperthyroid disorders | none |
| 25 | Medical Pharmacology- Drugs for treatment of diabetes mellitus 1 | none |
| 26 | Medical Pharmacology- Drugs for treatment of diabetes mellitus 2 | none |
| 27 | Medical Pharmacology- Drugs for treatment of diabetes mellitus 3 | none |
| 28 | Medical Pharmacology- Drugs for treatment of osteoporosis 1 | none |
| 29 | Tıbbi Farmakoloji - Osteoporoz tedavisine yönelik ilaçlar 2- | none |
| 30 | Medical Pharmacology- Drugs for treatment of pituitary disorders | none |
| 31 | Medical Pharmacology- Adrenal steroids | none |
| 32 | Medical Pharmacology- Questions, answers and discussion | none |
| 33 | Public Health -Community Nutrition | none |
| 34 | Public Health -Nutritional Epidemiology | none |
| 35 | Public Health -Epidemiology of Type 2 Diabetes | none |
| 36 | Public Health -School Health | none |
| 37 | Scientific Research-Cross-sectional Studies | none |
| 38 | Microbiology-Introduction to mycology | none |
| 39 | Microbiology -Superficial mycoses | none |
| 40 | Microbiology -LAB (1-2-3)-Clinically important fungi and preparation examination | |
| 41 | Radiology-Nuclear Medicine-Nuclear Medicine Applications and Treatments in Endocrine System | none |
| 42 | Internal Medicine – Hypothalamic -Pituitary Disorders (2) | none |
| 43 | Internal Medicine – Diseases of Posterior Pituitary | none |
| 44 | Adrenal Diseases | none |
| 45 | Endocrine hypertension | none |
| 46 | Lipid Disorders | none |
| 47 | Diseases of calcium metabolism 1-2 | none |
| 48 | Osteoporosis | none |
| 49 | Hirsutism and Polycystic Ovary Syndrome | none |
| 50 | Cross-sectional Studies |
| Resources |
| Patology: Vinay Kumar, Abul K. Abbas, Nelson Fausto, Richard Mitchell: Robbins Basic Pathology. 10 th ed. Saunders/Elsevier Edward C. Klatt: Robbins and Cotran Atlas of Pathology. 2nd ed. Saunders. online websites( Pathology outlines vb) lecture notes:ppt Pharmacology : 1.Kayaalp, SO: Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara. 2.Hardman JG, Limbird LE, Eds.: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, New York. 3.Katzung & Trevor: Farmakoloji, Ankara. Microbiyoloji: Microbiology: An Introduction (11th Edition), Gerard J. Tortora Internal medicine: Harrison Internal Medicine-İç hastalıkları Ders kitabı Uptodate database Greenspan : basiz and clinical endocrinology presentation notes-ppt Surgery: : schwartz principles of general surgery 10th edition Radiology and Pediatrics: Presentation notes-PPT slides |
| none |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | ||||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | ||||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | ||||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | ||||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | ||||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | ||||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | ||||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | ||||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | ||||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | ||||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | ||||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | ||||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | ||||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | ||||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |