Course Description

Course Description Course Outline Course Contribution to Program Qualifications Assessment Methods ECTS-Workload Detail Informations of the Course Numerical Data

Course Description

Course	Code	Semester	T+P (Hour)	Credit	ECTS
PHARMACOLOGY	-	Yearly	90+0	-	5

Course Program

Prerequisites Courses
Recommended Elective Courses

Language of Course	English
Course Level	First Cycle (Bachelor's Degree)
Course Type	Committee Course
Course Coordinator	Prof.Dr. Emine SALLAM
Name of Lecturer(s)	Prof.Dr. Emine SALLAM, Volkan AYDIN
Assistant(s)
Aim	To teach the general pharmacology subjects and the pharmacological properties of drugs that affect body systems.
Course Content	This course contains; Introduction to Pharmacology, Pharmacological Evaluation of New Drugs, Drug Absorbtion & Distribution & Metabolism, Histamine, Serotonin, Autacoids, Clinical Evaluation of New Drugs.,Toxic Effects of Drugs, Pharmacogenetic, Eicosanoids, Peptide Autacoids, Nitric Oxide, Drug Administration Routes, Traditional and Complementary Medicine Applications.,Drug Excreation, Factors Modifying the Effects of Drugs in Individuals, Dosage Forms of the Drugs, Drug-Receptor Relationship, Principles of Rational Drug Use.,Dose-concentration-effect Relationship, Mechanisms of drug actions.,Antianemic Drugs, Immunomodulator Drugs, Antineoplastic Agents,Antimicrobial Agents, Pharmacodynamic and pharmacokinetic drug interactions.,Monobactams, Beta Lactamase Inhibitors, Carbapenems, Vancomycin, Penicillins, Cephalosporins.,Anti-anaerobic Drugs, Aminoglycosides.,Sulfonamides & Cotrimoxazole, Tetracycline, Chloramphenicol, Fluoroquinolones, Macrolides, Antiviral Agents, Antifungal Agents.,Antiprotozoal Agents, Antihelmintic Agents, Pharmacotherapy of Ectoparasitic Infections.,Endocrin System Pharmacology., Agents That Affect Bone Mineral Homeostasis, Pancreatic Hormones, Antidiabetic Drugs.,ACTH, Adrenocorticosteroids, Adrenocortical Antagonists.,Antihypertensive Agents, Introduction to Autonomic Pharmacology, Drugs Used in Disorders of Coagulation, Antiplatelet Drugs, Anticoagulants and Fibrinolytic Agents.,Antianginal Drugs, Cholinoceptor-Activating & Cholinoceptor-Blocking Drugs, Muscarinic Receptor Agonists, Symphatomimetics, Symphatolytics, Nicotine, Ganglion-stimulating Agents, Ganglion Blocking Agents, Drugs used in acid-base and electrolyte imbalance.,Vasodilators, Drugs Used in Heart Failure, Hemostatic Agents, Plasma Volume Expanders, Blood and Plasma Products, Agents Used in Dyslipidemia.,Antiarrhythmic Drugs, Antihistamines, Antitussive Agents, Cold.,Bronchodilators, Expectorants & Surfactans, Vitamins, Therapeutic Use of Oxygen and Other Medical Gases.,The Gonadal Hormones & Inhibitors, Contraceptive Agents.,Diuretics.,Laxatives & Purgatives, Pharmacovigilance, Introduction to Clinical Pharmacology.,Emetics & Antiemetics.,Drugs used in the treatment of peptic ulcer.,Introduction to Central Nervous System Pharmacology, Antipsychotics & Antidepressants, General Anesthetics.,Central Nervous Systen Stimulants & Hallucinations, Narcotic Analgesis, Antiepilepic Drugs, Drug addiction and drugs of abuse.,Sedative-Hypnotic Drugs, The Alcohols, The Drugs Used in the Treatment of Headache.,The Treatment of Alzheimer's Disease, Antiparkinsonian Drugs.,Anti-inflammatory Drugs, Neuromuscular Blocking Drugs, Centrally Acting Muscle Relaxants, Local Anesthetics.,Medical Pharmacology (1,2) - Analgesics, anti-inflammatory and management of OA ,DMARDs and Pharmacotherapy of RA ,Pharmacotherapy of gout and hyperuricemia ,Principles of Neuropharmacology ,Hypnotics & Sedatives ,General & Local Anesthetics ,Pharmacotherapy of Degenerative Disorders ,Pharmacotherapy in Epilepsy,Pharmacotherapy of Depressive & Anxiety Disorders ,Pharmacotherapy of Psychosis & Mania ,Opioids & Abused Drugs ,- Drugs affecting kidney and electrolytes,- Drugs used in CKD, immunosuppression in transplantation, drug-induced nephrotoxicity ,- Drugs used for acid peptic disease ,- Drugs used for emesis ,Laxatives, antidiarrheal agents and drugs for IBS ,- Drugs used for inflammatory bowel disease ,Drugs used in arrythmia ,Drugs used in heart failure ,COPD and cough medications ,Antihyperlipidemic agents ,Drugs used in angina ,- Treatment of hypertension ,Drugs used in bronchial asthma ,Sympathomimetics and sympathetic depressants ,Introduction to cardiovascular medications ,Corticosteroids Pharmacology ,Drugs for treatment of pituitary disorders,Drugs for treatment of diabetes mellitus 1-2-3,Drugs for treatment of hypothyroid disorders.

Dersin Öğrenme Kazanımları	Teaching Methods	Assessment Methods
1. evaluate the basic subjects of the pharmacology. 1.1. identify the functions of the drug pharmacokinetics and pharmacodynamics. 1.2. explain the functions of drug pharmacokinetics and pharmacodynamics. 1.3. summarize the drugs pharmacokinetics and pharmacodynamics.	12, 16, 19, 4, 9	A
2. evaluate the drug toxicity and addiction. 2.1. identify the drug toxicity and abuse. 2.2. explain the drug toxicity and their mechanism. 2.3. give examples of drug toxicity, and drug abuse.	16, 19, 4, 9	A
3. evaluate the central nervous stystem (CNS) drugs. 3.1. identify the pharmacokinetics and pharmacodynamics of CNS drugs. 3.2. explain the functions such as pharmacokinetics and pharmacodynamics of CNS drugs. 3.3. give examples of CNS drugs.	12, 16, 19, 4, 9	A
4. evaluate the analgesics, anti-inflammatories and anesthetics. 4.1. identify the characteristics such as pharmacokinetics and pharmacodynamics of the analgesic, anti-inflammatory and anesthetic drugs. 4.2. interpret the mechanisms of analgesic, anti-inflammatory and anesthetic drugs action. 4.3. give examples of analgesic, anti-inflammatory and anesthetic drugs.	12, 16, 19, 4, 9	A
5. explain pharmacokinetics and pharmacodynamics of autonom drugs. They can also discuss their advers effect profiles and drug interactions. 5.1. summarize the pharmacokinetics, pharmacodynamics, adverse effects, contraindications and drug interactions of the autonom drugs. 5.2. interpret the mechanisms of autonom drugs. 5.3. give examples of autonomic drugs.	12, 13, 16, 19, 4, 9	A
6. explain the pharmacokinetics and pharmacodynamics of endocrin, cardiovascular, respiratuar and gastrointestinal system drugs. They can also discuss their advers effect profiles and drug interactions. 6.1. summarize the pharmacokinetic, pharmacodynamics, adverse effects, contraindications and drug interactions of the endocrin, cardiovascular, respiratuar and gastrointestinal system drugs. 6.2. interpret the mechanisms of endocrin, cardiovascular, respiratuar and gastrointestinal system drugs. 6.3. give examples of endocrin, cardiovascular, respiratuar and gastrointestinal system drugs.	12, 13, 16, 19, 4, 9	A

Teaching Methods:	12: Problem Solving Method, 13: Case Study Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 4: Inquiry-Based Learning, 9: Lecture Method
Assessment Methods:	A: Traditional Written Exam

Course Outline

Order	Subjects	Preliminary Work
1	Introduction to Pharmacology, Pharmacological Evaluation of New Drugs, Drug Absorbtion & Distribution & Metabolism, Histamine, Serotonin, Autacoids, Clinical Evaluation of New Drugs.	Preparation for the lecture notes previously issued.
2	Toxic Effects of Drugs, Pharmacogenetic, Eicosanoids, Peptide Autacoids, Nitric Oxide, Drug Administration Routes, Traditional and Complementary Medicine Applications.	Preparation for the lecture notes previously issued.
3	Drug Excreation, Factors Modifying the Effects of Drugs in Individuals, Dosage Forms of the Drugs, Drug-Receptor Relationship, Principles of Rational Drug Use.	Preparation for the lecture notes previously issued.
4	Dose-concentration-effect Relationship, Mechanisms of drug actions.	Preparation for the lecture notes previously issued.
5	Antianemic Drugs, Immunomodulator Drugs, Antineoplastic Agents	Preparation for the lecture notes previously issued.
6	Antimicrobial Agents, Pharmacodynamic and pharmacokinetic drug interactions.	Preparation for the lecture notes previously issued.
7	Monobactams, Beta Lactamase Inhibitors, Carbapenems, Vancomycin, Penicillins, Cephalosporins.	Preparation for the lecture notes previously issued.
8	Anti-anaerobic Drugs, Aminoglycosides.	Preparation for the lecture notes previously issued.
9	Sulfonamides & Cotrimoxazole, Tetracycline, Chloramphenicol, Fluoroquinolones, Macrolides, Antiviral Agents, Antifungal Agents.	Preparation for the lecture notes previously issued.
10	Antiprotozoal Agents, Antihelmintic Agents, Pharmacotherapy of Ectoparasitic Infections.	Preparation for the lecture notes previously issued.
11	Endocrin System Pharmacology.	Preparation for the lecture notes previously issued.
12	Agents That Affect Bone Mineral Homeostasis, Pancreatic Hormones, Antidiabetic Drugs.	Preparation for the lecture notes previously issued.
13	ACTH, Adrenocorticosteroids, Adrenocortical Antagonists.	Preparation for the lecture notes previously issued.
14	Antihypertensive Agents, Introduction to Autonomic Pharmacology, Drugs Used in Disorders of Coagulation, Antiplatelet Drugs, Anticoagulants and Fibrinolytic Agents.	Preparation for the lecture notes previously issued.
15	Antianginal Drugs, Cholinoceptor-Activating & Cholinoceptor-Blocking Drugs, Muscarinic Receptor Agonists, Symphatomimetics, Symphatolytics, Nicotine, Ganglion-stimulating Agents, Ganglion Blocking Agents, Drugs used in acid-base and electrolyte imbalance.	Preparation for the lecture notes previously issued.
16	Vasodilators, Drugs Used in Heart Failure, Hemostatic Agents, Plasma Volume Expanders, Blood and Plasma Products, Agents Used in Dyslipidemia.	Preparation for the lecture notes previously issued.
17	Antiarrhythmic Drugs, Antihistamines, Antitussive Agents, Cold.	Preparation for the lecture notes previously issued.
18	Bronchodilators, Expectorants & Surfactans, Vitamins, Therapeutic Use of Oxygen and Other Medical Gases.	Preparation for the lecture notes previously issued.
19	The Gonadal Hormones & Inhibitors, Contraceptive Agents.	Preparation for the lecture notes previously issued.
20	Diuretics.	Preparation for the lecture notes previously issued.
21	Laxatives & Purgatives, Pharmacovigilance, Introduction to Clinical Pharmacology.	Preparation for the lecture notes previously issued.
22	Emetics & Antiemetics.	Preparation for the lecture notes previously issued.
23	Drugs used in the treatment of peptic ulcer.	Preparation for the lecture notes previously issued.
24	Introduction to Central Nervous System Pharmacology, Antipsychotics & Antidepressants, General Anesthetics.	Preparation for the lecture notes previously issued.
25	Central Nervous Systen Stimulants & Hallucinations, Narcotic Analgesis, Antiepilepic Drugs, Drug addiction and drugs of abuse.	Önceden verilen ders notuna hazırlık.Preparation for the lecture notes previously issued.
26	Sedative-Hypnotic Drugs, The Alcohols, The Drugs Used in the Treatment of Headache.	Preparation for the lecture notes previously issued.
27	The Treatment of Alzheimer's Disease, Antiparkinsonian Drugs.	Preparation for the lecture notes previously issued.
28	Anti-inflammatory Drugs, Neuromuscular Blocking Drugs, Centrally Acting Muscle Relaxants, Local Anesthetics.	Preparation for the lecture notes previously issued.
29	Medical Pharmacology (1,2) - Analgesics, anti-inflammatory and management of OA
30	DMARDs and Pharmacotherapy of RA
31	Pharmacotherapy of gout and hyperuricemia
32	Principles of Neuropharmacology
33	Hypnotics & Sedatives
34	General & Local Anesthetics
35	Pharmacotherapy of Degenerative Disorders
36	Pharmacotherapy in Epilepsy
37	Pharmacotherapy of Depressive & Anxiety Disorders
38	Pharmacotherapy of Psychosis & Mania
39	Opioids & Abused Drugs
40	- Drugs affecting kidney and electrolytes
41	- Drugs used in CKD, immunosuppression in transplantation, drug-induced nephrotoxicity
42	- Drugs used for acid peptic disease
43	- Drugs used for emesis
44	Laxatives, antidiarrheal agents and drugs for IBS
45	- Drugs used for inflammatory bowel disease
46	Drugs used in arrythmia
47	Drugs used in heart failure
48	COPD and cough medications
49	Antihyperlipidemic agents
50	Drugs used in angina
51	- Treatment of hypertension
52	Drugs used in bronchial asthma
53	Sympathomimetics and sympathetic depressants
54	Introduction to cardiovascular medications
55	Corticosteroids Pharmacology
56	Drugs for treatment of pituitary disorders
57	Drugs for treatment of diabetes mellitus 1-2-3
58	Drugs for treatment of hypothyroid disorders

Resources

1. Kayaalp, SO: Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara. 2. Hardman JG, Limbird LE, Eds.: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, New York. 3. Katzung & Trevor: Farmakoloji, Ankara.

Goodman & Gilman's Pharmacological Basis of Treatment - / Laurence L.Brunton - John S.Lazo - Keith L.Parker Nobel Medical Bookstores Publications, Istanbul, 2008 Katzung & Trevor's Pharmacology Examination and Board Review: Eighth Edition McGraw-Hill Medical Publishing USA, 2008. Medical Pharmacology in the Direction of Rational Treatment 13th Edition - Prof.Dr. Oğuz Kayaalp, Pelikan Publications, 2012. Pharmacology for Health Sciences - Asist. Prof. A. Arzu SAYIN ŞAKUL, Istanbul Medical Publications, 2021

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
No	Program Qualification	Contribution Level
No	Program Qualification	1	2	3	4	5
1	PQ1: Knows the morphological and functional normal and abnormal structure of human body.		X
2	PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders.
3	PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health.
4	PQ4: Knows the methods of advancing his/her knowledge about health and its practice.	X
5	PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health.		X
6	PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems.	X
7	PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions.		X
8	PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health.
9	PQ9: Plans and conducts an advanced study of health independently.			X
10	PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health.			X
11	PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment.	X
12	PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude.			X
13	PQ13: Evaluates the information gained in the field of health with a critical approach.	X
14	PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally.			X
15	PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data.		X
16	PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates.		X
17	PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License.		X
18	PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health.			X
19	PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes.					X
20	PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts.
21	PQ21: Has sufficient awareness on occupational health and safety issues.

Assessment Methods

Contribution Level	Absolute Evaluation
Rate of Midterm Exam to Success		40
Rate of Final Exam to Success		60
Total		100

ECTS / Workload Table
Activities	Number of	Duration(Hour)	Total Workload(Hour)
Course Hours	0	0	0
Guided Problem Solving	0	0	0
Resolution of Homework Problems and Submission as a Report	0	0	0
Term Project	0	0	0
Presentation of Project / Seminar	0	0	0
Quiz	0	0	0
Midterm Exam	0	0	0
General Exam	0	0	0
Performance Task, Maintenance Plan	0	0	0
Total Workload(Hour)			0
*Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30=(0/30)**			0
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course