Course Description

Course Description Course Outline Course Contribution to Program Qualifications Assessment Methods ECTS-Workload Detail Informations of the Course Numerical Data

Course Description

Course	Code	Semester	T+P (Hour)	Credit	ECTS
Nervous System	07. Module	Fall Semester	127+22	-	10

Course Program

Prerequisites Courses
Recommended Elective Courses

Language of Course	English
Course Level	First Cycle (Bachelor's Degree)
Course Type	Committee
Course Coordinator	Assoc.Prof. Ali Timuçin ATAYOĞLU
Name of Lecturer(s)	Assoc.Prof. Ali Timuçin ATAYOĞLU
Assistant(s)
Aim	To have a knowledge about the structures and functions of the central nervous system, to understand the basic function of the nervous system and to have knowledge about the common diseases related to the nervous system with a multidisciplinary point of view
Course Content	This course contains; PHYSIOLOGY: Physiology of musculoskeletal system, Physiology of blood and circulatory system, Physiology of respiratory and digestive system, Physiology of nervous system and sensory system, Endocrine and urogenital system physiology.,ANATOMİ: Sinir sistemi hakında genel bilgi, Fossa axillaris, Plexus brachialis about nervous ,Sinir sistemine giriş, Medulla spinalis, Çıkan-İnen yollar, Medulla spinalis sendromları, Brakiyal pleksusun klinik anatomisi, Lumbal ve sakral pleksus, Plexus lumbalis ve plexus sacralis’in klinik anatomisi, Plexus cervicalis, Beyin sapı, Kranial sinirler 1-6 Kranial sinirler 7-12, Diencephalon, Cerebellum, Limbik sistem, Telencephalon diencephalon, cerebellum, limbic system, telecephalon , Beyin ventrikülleri, BOS, MSS zarları Beyin venöz sinüsleri, Serebrovasküler hastalıklar, Beyin sapı sendromları, MSS damarları, Otonom sinir sistemi., HISTOLOGY: Congenital malformations, Histopathology, Body cavities, Diaphragm and embryonic development of body cavities, Head and neck embryology, Musculoskeletal system embryology, Extremity development, Blood histology, Hematopoiesis, Cardiovascular system histology, Skin histology, Skin and appendix development, Cardiovascular system embryology histology of lymphoid system, embryology of lymphoid system, histology of respiratory system, respiratory system embryology, digestive system histology: digestive tract digestive system histology: digestive tract, embryology, integumental system embryology, nervous system histology and embryology, histology and embryology of specialized senses , Digestive System Histology, Digestive Glands Histology, Digestive System Embryology, Endocrine System Histology, Endocrine System Embryology, Urinary System Histology, Urinary System Embryology, Female Genital System em histology, Male genital system histology., Physiopathology Physiopathology of the musculoskeletal system Physiopathology of the blood and circulation Physiopathology of the respiratory and digestive system Physiopathology of the nervous system and sensory organs Physiopathology of the endocrine and urogenital system., Biophysics: General structure of nerve cells, membrane structure and properties of nerve cells, action potential in neurons, signal transduction, neurotransmitter materials and their effects on cells directly and indirectly, muscle biophysics and dynamics, structure of skeletal muscle cells, Nerve system, Nerst equation, Goldman equation, Vision biophysics and optic laws, Hearing biophysics and sound waves, Radiation biophysics: Radiation biopsy (particle and wave), Radiation biophysics, X-ray working principles, MR, fMRI, PET working principles, EEG, Olay Potentials, EEG, microwave and radio waves, ultrasound, visible rays, cosmic rays, Gamma rays, , Oscillations related to Olay..

Dersin Öğrenme Kazanımları	Teaching Methods	Assessment Methods
Counts the differences between thick and thin skin histology.
Explains the histological structure of the epidermis and counts its layers.
Explain the morphological features of keratinocytes.
Explain the structural features and functions of cells in the epidermis.
Explain the histological structure and vascularization of the dermis.
Explains the dermis innervation (nervous stimulation).
Explain the histological structures and functions of eccrine and apocrine sweat glands.
Counts the locations and properties of Sabese glands.
Explain the histology of the erector pili muscle.
Explain the histological structure of the hair follicle.
Explain the nail histology.
Explain the histological structure of the mammary gland.
Establishes the characteristics of the skin and its appendages and their relations with the clinic.
Interprets the preparations and images about the skin and its appendages.
Explain the development of the skin and its appendages.
Counts the clinical conditions related to the skin and its appendages.
Histologically distinguish the brain, cerebellum and spinal cord.
Explain the cerebellum cortex and its layers.
It explains the cells in the cerebellar cortex and the synapses they make.
Explain the histological structure of the cerebellum medulla.
Explain the histological structure of cerebral cortex and medulla.
Counts the types and characteristics of neurons in the brain and explains them together with their synapses.
Describe the cellular features of the choroid plexus.
Explain the histological structure of the medulla spinalis cortex and medulla.
Explain the locations of motor and sensory neurons.
Defines the histological structure of the central canal.
Defines the blood nerve barrier.
Explain the histological features and differences of meninges.
Interprets preparations and images related to the central nervous system.
Explain the organization of peripheral nerves.
Defines ganglia.
Counts the differences of cranio-spinal and autonomic (motor) ganglia.
Interprets preparations and images related to peripheral nerves.
Explain the differentiation of neural ectoderm.
Explain the formation of the neural tube.
Explain the formation of different brain regions from the neural tube.
Explain the origin and differentiation of neurons and glial cells.
Explain the origin, differentiation and embryonic development of medulla spinalis, pons, medulla, cerebrum and cerebellum.
Explain the origins and embryonic development of meninges and choroid plexus.
Explain the origin and embryonic development of peripheral nerve ganglia.
Explain the origin and embryonic development of peripheral nerves.
Counts the names of the layers of the eye and explains histological features.
Counts the names of the layers of the sclera and explains the histological features.
Counts the names of the layers of the cornea and explains the histological features.
Explains the structure of the limbus cornea and interprets the clinical significance of the shim duct.
Counts the layers of the choroid, ciliary body and iris and explains the histological features.
Counts the layers of the retina and explains the organization of its cells.
Explains the names and histological features of cells in the retina.
Explain the histological features and functions of specialized regions in the retina.
Explain the histological structure of the lens and interpret its clinical significance.
Explain the histological structure of the conjunctiva.
Explain the layers and histological structures of the eyelids.
Defines glands located on eyelids.
Explain the function of eyelid muscles and tarsal plate.
Explains the organization of tear glands and ducts and explains the histology of structures in the tear system.
Interprets eye preparations and images.
Counts the ear parts and structures.
Explain the histological structure of the outer ear, ear canal and eardrum.
Explain the histological structure of the middle ear.
Explain the histological structure of the Eustachian tube.
Defines the bony and membranous labyrinth structures in the inner ear.
Explain the histology of structures found in the bony and membranous labyrinth.
Explain the cells in the organ of Corti and the histology of the organ of Corti.
Interprets preparations and images related to the ear.
Counts the tissues from which the eye originates.
Explains eye development.
Defines the malformations seen in the eye.
Explain the structures from which the inner ear, middle ear and outer ear originate.
Explain the development of inner ear, middle ear and outer ear.
Defines congenital anomalies related to ear.

Teaching Methods:
Assessment Methods:

Course Outline

Order	Subjects	Preliminary Work
1	PHYSIOLOGY: Physiology of musculoskeletal system, Physiology of blood and circulatory system, Physiology of respiratory and digestive system, Physiology of nervous system and sensory system, Endocrine and urogenital system physiology.	-
2	ANATOMİ: Sinir sistemi hakında genel bilgi, Fossa axillaris, Plexus brachialis about nervous ,Sinir sistemine giriş, Medulla spinalis, Çıkan-İnen yollar, Medulla spinalis sendromları, Brakiyal pleksusun klinik anatomisi, Lumbal ve sakral pleksus, Plexus lumbalis ve plexus sacralis’in klinik anatomisi, Plexus cervicalis, Beyin sapı, Kranial sinirler 1-6 Kranial sinirler 7-12, Diencephalon, Cerebellum, Limbik sistem, Telencephalon diencephalon, cerebellum, limbic system, telecephalon , Beyin ventrikülleri, BOS, MSS zarları Beyin venöz sinüsleri, Serebrovasküler hastalıklar, Beyin sapı sendromları, MSS damarları, Otonom sinir sistemi.	-
3	HISTOLOGY: Congenital malformations, Histopathology, Body cavities, Diaphragm and embryonic development of body cavities, Head and neck embryology, Musculoskeletal system embryology, Extremity development, Blood histology, Hematopoiesis, Cardiovascular system histology, Skin histology, Skin and appendix development, Cardiovascular system embryology histology of lymphoid system, embryology of lymphoid system, histology of respiratory system, respiratory system embryology, digestive system histology: digestive tract digestive system histology: digestive tract, embryology, integumental system embryology, nervous system histology and embryology, histology and embryology of specialized senses , Digestive System Histology, Digestive Glands Histology, Digestive System Embryology, Endocrine System Histology, Endocrine System Embryology, Urinary System Histology, Urinary System Embryology, Female Genital System em histology, Male genital system histology.	-
4	Physiopathology Physiopathology of the musculoskeletal system Physiopathology of the blood and circulation Physiopathology of the respiratory and digestive system Physiopathology of the nervous system and sensory organs Physiopathology of the endocrine and urogenital system.	-
5	Biophysics: General structure of nerve cells, membrane structure and properties of nerve cells, action potential in neurons, signal transduction, neurotransmitter materials and their effects on cells directly and indirectly, muscle biophysics and dynamics, structure of skeletal muscle cells, Nerve system, Nerst equation, Goldman equation, Vision biophysics and optic laws, Hearing biophysics and sound waves, Radiation biophysics: Radiation biopsy (particle and wave), Radiation biophysics, X-ray working principles, MR, fMRI, PET working principles, EEG, Olay Potentials, EEG, microwave and radio waves, ultrasound, visible rays, cosmic rays, Gamma rays, , Oscillations related to Olay.	-

Resources

Clinical neuroanatomy. Snell, Richard S. Lippincott Williams & Wilkins, 2010. Gray's clinical neuroanatomyMancall, Elliott L., and David G. Brock. . Elsevier Health Sciences, 2011. Pathophysiology: Concepts of Altered Health States - Carol Mattson Porth Essential Concepts in Molecular Pathology - William B. Coleman Pathophysiology - FUunctional Alterations in Human Health, Carie A. Braun..Tıbbi Fizyoloji – Guyton, Ganong’s Review of Medical Physiology, Molecular Biology of the cell – Alberts, Principles of Neural Science.......Biyofizik, Ferit Pehlivan, Hacettepe Taş Kitapevi. Nörobiyofizik, Ferhan Esen-Hamza Esen, Ankara Nobel Tıp Kitapevi, Biopysics Roland Glaser.....Gartner L.P., Hiatt J.L.: Color Text Book of Histology. Second ed. SAUNDERS. Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Sadler T.W: Langman's Medical Embryology, Eleventh Edition. Lippincott Williams & Wilkins, USA Schoenwolf G.C.: Larsen’s Human Embryology. 4. Ed. CHURCHILL LIVINGSTONE ELSEVIER Stevens A., Human Histology, Third Ed. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Power Point slides

Medical Physiology – Guyton Ganong’s Review of Medical Physiology Molecular Biology of the cell - Alberts Principles of Neurological Sciences - Kandel Color Atlas of Physiology Color Atlas of Pathophysiology -Moore K, AF. Dalley: Clinically oriented anatomy. Seventh ed. Lippincot Williams &Wilkins Company, Philadelphia, 2013- Drake, Richard, A. Wayne Vogl, and Adam WM Mitchell. Gray's anatomy for students. Elsevier Health Sciences, 2014. -Netter FH. Atlas of human anatomy (second edition). USA, Novartis, 1997: 268. -Putz R, Pabst R. Sobotta atlas of human anatomy Volume 2 12th English Ed. Munich, Urban & Schwarzenberg 1994: 165. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Pathophysiology: Concepts of Altered Health States - Carol Mattson Porth 2. Essential Concepts in Molecular Pathology - William B. Coleman 3. Pathophysiology - FUunctional Alterations in Human Health, Carie A. Braun 4. Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty, 6th ed. Leonard S. Lilly (ed). Wolters Kluver, 2016. 5. Guyton and Hall Textbook of Medical Physiology, 13th ed. John E. Hall (ed). Elsevier, 2016. Power Point slides

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
No	Program Qualification	Contribution Level
No	Program Qualification	1	2	3	4	5
1	PQ1: Knows the morphological and functional normal and abnormal structure of human body.
2	PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders.
3	PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health.
4	PQ4: Knows the methods of advancing his/her knowledge about health and its practice.
5	PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health.
6	PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems.
7	PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions.
8	PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health.
9	PQ9: Plans and conducts an advanced study of health independently.
10	PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health.
11	PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment.
12	PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude.
13	PQ13: Evaluates the information gained in the field of health with a critical approach.
14	PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally.
15	PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data.
16	PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates.
17	PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License.
18	PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health.
19	PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes.
20	PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts.
21	PQ21: Has sufficient awareness on occupational health and safety issues.

Assessment Methods

Contribution Level	Absolute Evaluation
Rate of Midterm Exam to Success		60
Rate of Final Exam to Success		40
Total		100

ECTS / Workload Table
Activities	Number of	Duration(Hour)	Total Workload(Hour)
Course Hours	27	5	135
Course Hours	10	2	20
Guided Problem Solving	0	0	0
Guided Problem Solving	0	0	0
Resolution of Homework Problems and Submission as a Report	0	0	0
Term Project	6	3	18
Term Project	0	0	0
Presentation of Project / Seminar	0	0	0
Presentation of Project / Seminar	0	0	0
Quiz	0	0	0
Midterm Exam	15	5	75
General Exam	15	5	75
General Exam	0	0	0
Performance Task, Maintenance Plan	0	0	0
Total Workload(Hour)			323
*Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30=(323/30)**			11
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course