Course Description

Course Description Course Outline Course Contribution to Program Qualifications Assessment Methods ECTS-Workload Detail Informations of the Course Numerical Data

Course Description

Course	Code	Semester	T+P (Hour)	Credit	ECTS
From Cell to Human Body	05. Module	Spring Semester	67+22	-	7

Course Program

Prerequisites Courses
Recommended Elective Courses

Language of Course	English
Course Level	First Cycle (Bachelor's Degree)
Course Type	Committee
Course Coordinator	Assist.Prof. Ali Behram SALAR
Name of Lecturer(s)	Assist.Prof. Ali Behram SALAR
Assistant(s)
Aim	The aim of this committee is to enable students to acquire cellular, molecular, biological and genetic, histological, anatomical and biochemical concepts that will form the basis of clinical studies, and to get to know the human body in the light of this information.
Course Content	This course contains; MEDICAL GENETICS: Basic structure and functions of proteins, Genetic material of the cell: DNA, chromosomes and genome, DNA replication, repair and recombination, Transfer of genetic information from DNA to protein, Control mechanisms of gene expression, Epigenetics,HISTOLOGY AND EMBRYOLOGY: Introduction to histology and introduction to microscope, Microscopes and Microscopy techniques, Immunohistochemistry, Using Lab-Microscope and Observation of Cells, Cell Types and Cell Membrane, Golgi-ER-Lysosome, Mitochondria-Ribosome, Nucleus and Nucleolus, Introduction to Cell epithelium, connective-support, muscle and nerve tissue), Covering Epithelium, Glandular Epithelium, Lab-epithelial, Connective Tissue, Adipose Tissue, Lab-Connective Tissue-fatty tissue, Cartilage Tissue, lab-cartilage, Bone Tissue, Neurohistology, lab-bone ,striated muscle, smooth muscle, cardiac muscle, Lab-muscle, Introduction to General Embryology and Terminology, Oogenesis, Spermatogenesis, Fertilization, Implantation, 2nd Week of Embryonic Development, 3rd Week of Embryonic Development, Neurogenesis, Organogenesis, Extraembryonic Structures,BIOCHEMISTRY: Molecular meaning of life, Bioenergy: Carbohydrate metabolism, Energy storage: Glycogen production and destruction, Energy production: Glycolysis, Energy conversion I: Citric acid cycle, Energy conversion II: Pentose phosphate pathway, Glucose biosynthesis: Gluconeogenesis, Metabolic control of glucose, Lipids and Fatty acids, Oxidation of fatty acids, Ketogenesis, Lipoproteins, Sphingolipids, Steroids, Lipogenesis, Membranes and transport, Oxidative phosphorylation, Biological oxidation-antioxidants, Enzymes, Signal transmission, Hormones and their structure, The mechanism of action of hormones, the mechanism of action of hormones, Vita molecules (1),Inorganic molecules (2),Amino acids and properties,Amino acid synthesis and degradation,Biological amines,Urea synthesis,Structure of proteins,Classification of proteins,Globular proteins (Hemoglobin),Protein analysis methods,Nutritional biochemistry acids,Nucleic Buffer systems ,Body fluids ,Water metabolism,ANATOMY: Introduction to anatomy and general concepts, upper extremity bones and joints, lower extremity bones and joints, columna vertebralis and joints, cranium bones and joints, mimic muscles.

Dersin Öğrenme Kazanımları	Teaching Methods	Assessment Methods
Evaluates proteins in terms of their structure and functions, explains the purpose of analysis methods.	10, 16, 9	A
Explains the clinical meaning of protein denaturation, comprehends the events that occur in intracellular protein degradation.	10, 16, 9	A
Comprehends buffer systems, acid-base balance, acidosis and alkalosis	10, 16, 9	A
Explains the basic concepts and principles of heredity in medical genetics, comprehends genetic diseases and diagnostic methods.	16, 9	A
Describes general first aid concepts.	16, 9	A
Describes the first aid to be applied in traumas, environmental emergencies and poisonings.	9	D
Describes patient and injured transport techniques.	10, 9
Distinguishes structures in a healthy human body at the level of microscopic anatomy.	16, 6	D
Compares morphology and function at molecular, cellular, tissue and organ level.	10, 9	A, D
Explains the changes in basic organ structures and functions that occur at different stages of the embryonic process.	10	A
Distinguishes the skull bones and the formations on them.	10, 16	A
Distinguishes head, neck and trunk muscles.	16, 6	A
Examines the reproductive cells under the microscope.	17, 6	D
Gains the ability to transport the sick and injured.	10, 16, 6, 9
Gains protein analysis skills.	17	A, D
Shows head, neck and trunk muscles.	16, 6	D
Discerns the skull bones and the formations on them.	16, 9	D
Understands the importance of first aid in emergency situations.	10, 13, 16	A
Acts responsibly and shows respect while working on human tissue samples such as bone cadavers.	10, 9	D

Teaching Methods:	10: Discussion Method, 13: Case Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 6: Experiential Learning, 9: Lecture Method
Assessment Methods:	A: Traditional Written Exam, D: Oral Exam

Course Outline

Order	Subjects	Preliminary Work
1	MEDICAL GENETICS: Basic structure and functions of proteins, Genetic material of the cell: DNA, chromosomes and genome, DNA replication, repair and recombination, Transfer of genetic information from DNA to protein, Control mechanisms of gene expression, Epigenetics
2	HISTOLOGY AND EMBRYOLOGY: Introduction to histology and introduction to microscope, Microscopes and Microscopy techniques, Immunohistochemistry, Using Lab-Microscope and Observation of Cells, Cell Types and Cell Membrane, Golgi-ER-Lysosome, Mitochondria-Ribosome, Nucleus and Nucleolus, Introduction to Cell epithelium, connective-support, muscle and nerve tissue), Covering Epithelium, Glandular Epithelium, Lab-epithelial, Connective Tissue, Adipose Tissue, Lab-Connective Tissue-fatty tissue, Cartilage Tissue, lab-cartilage, Bone Tissue, Neurohistology, lab-bone ,striated muscle, smooth muscle, cardiac muscle, Lab-muscle, Introduction to General Embryology and Terminology, Oogenesis, Spermatogenesis, Fertilization, Implantation, 2nd Week of Embryonic Development, 3rd Week of Embryonic Development, Neurogenesis, Organogenesis, Extraembryonic Structures
3	BIOCHEMISTRY: Molecular meaning of life, Bioenergy: Carbohydrate metabolism, Energy storage: Glycogen production and destruction, Energy production: Glycolysis, Energy conversion I: Citric acid cycle, Energy conversion II: Pentose phosphate pathway, Glucose biosynthesis: Gluconeogenesis, Metabolic control of glucose, Lipids and Fatty acids, Oxidation of fatty acids, Ketogenesis, Lipoproteins, Sphingolipids, Steroids, Lipogenesis, Membranes and transport, Oxidative phosphorylation, Biological oxidation-antioxidants, Enzymes, Signal transmission, Hormones and their structure, The mechanism of action of hormones, the mechanism of action of hormones, Vita molecules (1),Inorganic molecules (2),Amino acids and properties,Amino acid synthesis and degradation,Biological amines,Urea synthesis,Structure of proteins,Classification of proteins,Globular proteins (Hemoglobin),Protein analysis methods,Nutritional biochemistry acids,Nucleic Buffer systems ,Body fluids ,Water metabolism
4	ANATOMY: Introduction to anatomy and general concepts, upper extremity bones and joints, lower extremity bones and joints, columna vertebralis and joints, cranium bones and joints, mimic muscles

Resources

1. Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter “Essential Cell Biology” Fourth Edition, Garland Science Publishers, USA, 2013. 2. Kierzsenbaum A.L., Histology and Cell Biology, An Introduction to Pathology, Third ed. SAUNDERS. 3. Gartner L.P., Hiatt J.L.: Color Text Book of Histology. Second ed. SAUNDERS. 4. Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP 5. Sadler T.W: Langman's Medical Embryology, Eleventh Edition. Lippincott Williams & Wilkins, USA Schoenwolf G.C.: Larsen’s Human Embryology. 4. Ed. CHURCHILL LIVINGSTONE ELSEVIER 6. Clinical Chemistry Pillincott Williams and Wilkins,Bishop,Fody, Schoeff, 2013 7.Henry's Clinical Diagnosis and Managemen by Laboratory Methods, McPherson and Pincus, Elsevier Saunders, 2011. 3.Basic and Appliend Biochemisty, Nesrin Emekli, Nobel Tıp Kitapevleri Clinical Chemistry Pillincott Williams and Wilkins,Bishop,Fody, Schoeff, 2013 Henry's Clinical Diagnosis and Managemen by Laboratory Methods, McPherson and Pincus, Elsevier Saunders, 2011. 3.Basic and Appliend Biochemisty, Nesrin Emekli, Nobel Tıp Kitapevleri

1. Stevens A., Human Histology, Third Ed. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP 2. Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. 3. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA 4. Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
No	Program Qualification	Contribution Level
No	Program Qualification	1	2	3	4	5
1	PQ1: Knows the morphological and functional normal and abnormal structure of human body.
2	PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders.
3	PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health.
4	PQ4: Knows the methods of advancing his/her knowledge about health and its practice.
5	PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health.
6	PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems.
7	PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions.
8	PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health.
9	PQ9: Plans and conducts an advanced study of health independently.
10	PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health.
11	PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment.
12	PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude.
13	PQ13: Evaluates the information gained in the field of health with a critical approach.
14	PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally.
15	PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data.
16	PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates.
17	PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License.
18	PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health.
19	PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes.
20	PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts.
21	PQ21: Has sufficient awareness on occupational health and safety issues.

Assessment Methods

Contribution Level	Absolute Evaluation
Rate of Midterm Exam to Success		60
Rate of Final Exam to Success		40
Total		100

ECTS / Workload Table
Activities	Number of	Duration(Hour)	Total Workload(Hour)
Course Hours	109	1	109
Guided Problem Solving	0	0	0
Resolution of Homework Problems and Submission as a Report	24	1	24
Term Project	30	2	60
Presentation of Project / Seminar	0	0	0
Quiz	0	0	0
Midterm Exam	0	0	0
General Exam	60	1	60
Performance Task, Maintenance Plan	0	0	0
Total Workload(Hour)			253
*Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30=(253/30)**			8
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course