Course Description

Course Description Course Outline Course Contribution to Program Qualifications Assessment Methods ECTS-Workload Detail Informations of the Course Numerical Data

Course Description

Course	Code	Semester	T+P (Hour)	Credit	ECTS
BIOCHEMISTRY	-	Yearly	74+10	-	6

Course Program

Pazartesi 11:00-11:45

Pazartesi 12:00-12:45

Pazartesi 13:30-14:15

Pazartesi 14:30-15:15

Çarşamba 13:30-14:15

Çarşamba 14:30-15:15

Perşembe 09:00-09:45

Perşembe 10:00-10:45

Perşembe 11:00-11:45

Perşembe 12:00-12:45

Cuma 11:00-11:45

Cuma 12:00-12:45

Prerequisites Courses
Recommended Elective Courses

Language of Course	English
Course Level	First Cycle (Bachelor's Degree)
Course Type	Committee Course
Course Coordinator	Assoc.Prof. Sultan Sibel ERDEM
Name of Lecturer(s)	Assoc.Prof. Sultan Sibel ERDEM, Assoc.Prof. Saime BATIREL, Assist.Prof. Nihan VERİMLİ
Assistant(s)	Assoc. Prof. S. Sibel ERDEM
Aim	The aim of this course is Describe the structure, organisation and functions of living matter in molecular terms. How do their interactions lead to the assembly of organized macro molecular structures.
Course Content	This course contains; Moleculer fundamental of life,Bioenergy:carbohydrate metabolism ,Energy storage:Glycogen synthesis and catabolism ,Energy production: Glycolysis ,Energy transformation I: Citric acid cycle ,Pendose phosphate pathway ,Glucose biosynthesis:Glycogenesis,Metabolic control of glucose,Lipids and fatty acids,Oxidation of fatty acids,Blood glucose assay,Lipoproteins,Sphingolipids ,Steroids,Lipogenesis ,Membrane and transport ,Oxidative phosphorylation ,Biologic oxidation and antioxidants ,Enyzmes and enzyme regulations,Signal transduction ,Structure of hormones,Mechanism action of hormone,Structure of vitamins,Mechanism action of vitamins,Inorganic molecules (1),Inorganic molecules (2),Amino acids and properties,Biosynthesis and catabolism of amino acids,Biologic amines,Urea synthesis,Structure of proteins,Clasifications of proteins,Globuler protein (Hemoglobine),Proteins analysis methods,Nutritional biochemistry,Nucleic acids,Buffer systems,Body fluids,Water metabolism.

Dersin Öğrenme Kazanımları	Teaching Methods	Assessment Methods
1.1.Solve structure , digestion and absorption of carbohydrates, lipids and proteins.	16, 17, 19, 9	A, D, E, G
1.2.Categorize and compare the macro and micro minerals.	16, 17, 19, 9	A, D, E, G
1.3.Compare and question the hormones and enzymes.	16, 17, 19, 9	A, D, E, G
1.4.Understand the structure and functions of vitamines.	16, 17, 19, 9	A, D, E, G
2-Question the function of macroromolecules in the cell and understand insufficient dietary quantities of even one vitamin or amino acid can quickly limit the synthesis and lower the body level of many essential proteins.	16, 17, 19, 9	A, D, E, G
2.1.Solve the important of structure of carbohydrates within the cell and cell membrane.	16, 17, 19, 9	A, D, E, G
3-Question the relationship between macromolecules and energy.	16, 17, 19, 9	A, D, E, G
3.1.Question the metabolic fate of glucose.	16, 17, 19, 9	A, D, E, G
3.2.Solve the relationship between biological oxidation and fatty acids breaks down and synthesis.	16, 17, 19, 9	A, D, E, G
3.3.Question the de novo synthesis of glucose and fatty acids.	16, 17, 19, 9	A, D, E, G
3.4.Interpret the proteins in the energy production.	16, 17, 19, 9	A, D, E, G
3.5.Question the electron transport chain.	16, 17, 19, 9	A, D, E, G
4-Compare the relationship of body fluids.	16, 17, 19, 9	A, D, E, G
4.1.Solve the properties of urine and relate the kidney functions.	16, 17, 19, 9	A, D, E, G
4.2.Demonstrate the blood pH and buffer systems.	16, 17, 19, 9	A, D, E, G
4.3.Question the saliva andother body fulids.	16, 17, 19, 9	A, D, E, G
4.4.Interpret the important of water in the metabolism.	16, 17, 19, 9	A, D, E, G
5-Reach the printed and electronic information sources	16, 17, 19, 9	A, D, E, G
6-With these information, develop analytical thinking and concepts.	16, 17, 19, 9	A, D, E, G
1. Compere the structure of macro molecules in the organism.	16, 17, 19, 9	A, D, E, G
2.2. Solve the important lipids within the cell and cell membrane.	16, 17, 19, 9	A, D, E, G
2.3. Question of proteins within the cell and cell membrane.	16, 17, 19, 9	A, D, E, G
2.4. Compare the macrominerals in the metabolism.	16, 17, 19, 9	A, D, E, G
2.5. Compare the effect of hormone, enzyme and vitamins on the proteins, carbohydrates and lipids.	16, 17, 19, 9	A, D, E, G

Teaching Methods:	16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method
Assessment Methods:	A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz

Course Outline

Order	Subjects	Preliminary Work
1	Moleculer fundamental of life	references 1,2,3,4,5
2	Bioenergy:carbohydrate metabolism	references 1,2,3,4,5
3	Energy storage:Glycogen synthesis and catabolism	references 1,2,3,4,5
4	Energy production: Glycolysis	references 1,2,3,4,5
5	Energy transformation I: Citric acid cycle	references 1,2,3,4,5
6	Pendose phosphate pathway	references 1,2,3,4,5
7	Glucose biosynthesis:Glycogenesis	references 1,2,3,4,5
8	Metabolic control of glucose	references 1,2,3,4,5
9	Lipids and fatty acids	references 1,2,3,4,5
10	Oxidation of fatty acids	references 1,2,3,4,5
11	Blood glucose assay	references 1,2,3,4,5
12	Lipoproteins	references 1,2,3,4,5
13	Sphingolipids	references 1,2,3,4,5
14	Steroids	references 1,2,3,4,5
15	Lipogenesis	references 1,2,3,4,5
16	Membrane and transport	references 1,2,3,4,5
17	Oxidative phosphorylation	references 1,2,3,4,5
18	Biologic oxidation and antioxidants	references 1,2,3,4,5
19	Enyzmes and enzyme regulations	references 1,2,3,4,5
20	Signal transduction	references 1,2,3,4,5
21	Structure of hormones	references 1,2,3,4,5
22	Mechanism action of hormone	references 1,2,3,4,5
23	Structure of vitamins	references 1,2,3,4,5
24	Mechanism action of vitamins	References 1,2,3,4,5
25	Inorganic molecules (1)	references 1,2,3,4,5
26	Inorganic molecules (2)	references 1,2,3,4,5
27	Amino acids and properties	references 1,2,3,4,5
28	Biosynthesis and catabolism of amino acids	references 1,2,3,4,5
29	Biologic amines	References 1,2,3,4,5
30	Urea synthesis	references 1,2,3,4,5
31	Structure of proteins	references 1,2,3,4,5
32	Clasifications of proteins	references 1,2,3,4,5
33	Globuler protein (Hemoglobine)	references 1,2,3,4,5
34	Proteins analysis methods	references 1,2,3,4,5
35	Nutritional biochemistry	references 1,2,3,4,5
36	Nucleic acids	references 1,2,3,4,5
37	Buffer systems	references 1,2,3,4,5
38	Body fluids	references 1,2,3,4,5
39	Water metabolism	references 1,2,3,4,5

Resources

1.Experimental Biochemistry for Medical Sciences (Türkan Yiğitbaşı,S.Sibel Erdem,Perinur Bozaykut, Nesrin Emekli), 2.Lippincott Biochemistry, 3.Harper's Biochemistry, 4.Lehninger Principles of Biochemistry, 5.Henry's Clinical Diagnosis and Management by Laboratory Methods.

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
No	Program Qualification	Contribution Level
No	Program Qualification	1	2	3	4	5
1	PQ1: Knows the morphological and functional normal and abnormal structure of human body.
2	PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders.
3	PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health.
4	PQ4: Knows the methods of advancing his/her knowledge about health and its practice.
5	PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health.
6	PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems.
7	PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions.
8	PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health.
9	PQ9: Plans and conducts an advanced study of health independently.
10	PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health.
11	PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment.
12	PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude.
13	PQ13: Evaluates the information gained in the field of health with a critical approach.
14	PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally.
15	PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data.
16	PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates.
17	PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License.
18	PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health.
19	PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes.
20	PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts.
21	PQ21: Has sufficient awareness on occupational health and safety issues.

Assessment Methods

Contribution Level	Absolute Evaluation
Rate of Midterm Exam to Success		40
Rate of Final Exam to Success		60
Total		100

ECTS / Workload Table
Activities	Number of	Duration(Hour)	Total Workload(Hour)
Course Hours	15	3	45
Course Hours	0	0	0
Guided Problem Solving	0	0	0
Guided Problem Solving	8	1	8
Resolution of Homework Problems and Submission as a Report	0	0	0
Term Project	4	2	8
Term Project	0	0	0
Presentation of Project / Seminar	0	0	0
Presentation of Project / Seminar	0	0	0
Quiz	0	0	0
Midterm Exam	15	5	75
Midterm Exam	0	0	0
General Exam	15	5	75
General Exam	0	0	0
Performance Task, Maintenance Plan	0	0	0
Performance Task, Maintenance Plan	0	0	0
Total Workload(Hour)			211
*Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30=(211/30)**			7
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course