Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| From Molecule to Cell | 02. Module | Fall Semester | 94+24 | - | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee |
| Course Coordinator | Assist.Prof. Kıvanç KÖK |
| Name of Lecturer(s) | Assist.Prof. Kıvanç KÖK |
| Assistant(s) | |
| Aim | The aim of this committee is to introduce biologically important molecules acting in the structure and function of the cell and the chemical reactions taking place in the cell for the survival of the cell. It also aims to provide understanding the important biochemical molecules (such as DNA, RNA, ATP, cAMP, proteins, peptides, amino acids, major hormones etc.) and their functions in living systems and comprehend biochemical transformations of these important molecules. |
| Course Content | This course contains; Medical Biology and Genetics: Basic structure and functions of proteins, Genetic material of the cell, DNA, chromosomes and genome, DNA replication, repair and recombination, Transfer of genetic information from DNA to protein, Control mechanisms of gene expression and cellular genetic switches, Advanced molecular techniques, Molecular fundamental biology and clinical applications of techniques,Physiology: An overview of physiology, including definitions and applications. Functions of the cell membrane,Transport of substances across the cell membrane, Cell volume regulation, Mechanics of the cell,Principles of Scientific Research and Access to Information: Definition and principles of scientific research, Types and stages of scientific research, Definition of scientific publication, Types of scientific publication, Access to electronic data sources, Scientific data analysis,Biophysics: Physics and its branches, physical quantities, SI unit system and general equations, Introduction to biophysics, definition of biophysics, differences and common points between physics and biophysics,Organic Chemistry: Alkyl halides, nucleophilic substitution reactions, organic compounds containing CO and CS, Acidity-basicity, carboxylic acids, organic compounds containing C=O, organic compounds containing N, Aromatic compounds, Biomolecules: carbohydrates, lipids, Biomolecules: amino acids, peptides, Biomolecules: proteins and enzymes, enzyme kinetics,Biochemistry: the molecular meaning of life. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Learns the chemical reactions occurring in living organisms and the properties of organic compounds. | 12, 14, 17, 9 | A, D |
| Learn about structural molecular cell biology, medical biology, and genetic concepts, as well as molecular mechanisms of cellular functioning, which will serve as the foundation for clinical studies. | 14, 16, 9 | A |
| It provides a general understanding of physiological mechanisms, structure-function relationships in the cell membrane, and basic principles of cell mechanics. | 14, 16, 9 | A |
| Learns about scientific research, its general principles and methods, and how to access scientific information. | 10, 12, 13, 14, 19, 23, 9 | A |
| Learns the fundamental concepts and methods of biophysics. | 14, 16, 9 | A |
| Can describe the chemical reactions in the cell at the molecular level and explain the changes that occur in these reactions in pathological conditions. | 12, 17, 9 | A, D |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 13: Case Study Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 23: Concept Map Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Medical Biology and Genetics: Basic structure and functions of proteins, Genetic material of the cell, DNA, chromosomes and genome, DNA replication, repair and recombination, Transfer of genetic information from DNA to protein, Control mechanisms of gene expression and cellular genetic switches, Advanced molecular techniques, Molecular fundamental biology and clinical applications of techniques | |
| 2 | Physiology: An overview of physiology, including definitions and applications. Functions of the cell membrane,Transport of substances across the cell membrane, Cell volume regulation, Mechanics of the cell | |
| 3 | Principles of Scientific Research and Access to Information: Definition and principles of scientific research, Types and stages of scientific research, Definition of scientific publication, Types of scientific publication, Access to electronic data sources, Scientific data analysis | |
| 4 | Biophysics: Physics and its branches, physical quantities, SI unit system and general equations, Introduction to biophysics, definition of biophysics, differences and common points between physics and biophysics | |
| 5 | Organic Chemistry: Alkyl halides, nucleophilic substitution reactions, organic compounds containing CO and CS, Acidity-basicity, carboxylic acids, organic compounds containing C=O, organic compounds containing N, Aromatic compounds, Biomolecules: carbohydrates, lipids, Biomolecules: amino acids, peptides, Biomolecules: proteins and enzymes, enzyme kinetics | |
| 6 | Biochemistry: the molecular meaning of life |
| Resources |
| 1. Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter “Essential Cell Biology” Fourth Edition, Garland Science Publishers, USA, 2013 2. Nesrin Emekli, Temel ve Uygulamalı Biyokimya 3. Guyton, Tıbbi Fizyoloji 4. Zeynel Dinler, Bilimsel Araştırma ve E- Kaynaklar 5. Roland Glaser, Biophysics 6. Paula Y. Bruice. Organic Chemistry 7. ed., Pearson, 2013. ISBN: 10-0-321-69768-5 |
| Course presentations and notes |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | ||||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | ||||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | ||||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | ||||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | ||||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | ||||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | ||||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | ||||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | ||||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | ||||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | ||||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | ||||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | ||||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | ||||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 5 | 23 | 115 | |||
| Guided Problem Solving | 10 | 3 | 30 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 30 | 30 | |||
| General Exam | 2 | 30 | 60 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 235 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(235/30) | 8 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| From Molecule to Cell | 02. Module | Fall Semester | 94+24 | - | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee |
| Course Coordinator | Assist.Prof. Kıvanç KÖK |
| Name of Lecturer(s) | Assist.Prof. Kıvanç KÖK |
| Assistant(s) | |
| Aim | The aim of this committee is to introduce biologically important molecules acting in the structure and function of the cell and the chemical reactions taking place in the cell for the survival of the cell. It also aims to provide understanding the important biochemical molecules (such as DNA, RNA, ATP, cAMP, proteins, peptides, amino acids, major hormones etc.) and their functions in living systems and comprehend biochemical transformations of these important molecules. |
| Course Content | This course contains; Medical Biology and Genetics: Basic structure and functions of proteins, Genetic material of the cell, DNA, chromosomes and genome, DNA replication, repair and recombination, Transfer of genetic information from DNA to protein, Control mechanisms of gene expression and cellular genetic switches, Advanced molecular techniques, Molecular fundamental biology and clinical applications of techniques,Physiology: An overview of physiology, including definitions and applications. Functions of the cell membrane,Transport of substances across the cell membrane, Cell volume regulation, Mechanics of the cell,Principles of Scientific Research and Access to Information: Definition and principles of scientific research, Types and stages of scientific research, Definition of scientific publication, Types of scientific publication, Access to electronic data sources, Scientific data analysis,Biophysics: Physics and its branches, physical quantities, SI unit system and general equations, Introduction to biophysics, definition of biophysics, differences and common points between physics and biophysics,Organic Chemistry: Alkyl halides, nucleophilic substitution reactions, organic compounds containing CO and CS, Acidity-basicity, carboxylic acids, organic compounds containing C=O, organic compounds containing N, Aromatic compounds, Biomolecules: carbohydrates, lipids, Biomolecules: amino acids, peptides, Biomolecules: proteins and enzymes, enzyme kinetics,Biochemistry: the molecular meaning of life. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Learns the chemical reactions occurring in living organisms and the properties of organic compounds. | 12, 14, 17, 9 | A, D |
| Learn about structural molecular cell biology, medical biology, and genetic concepts, as well as molecular mechanisms of cellular functioning, which will serve as the foundation for clinical studies. | 14, 16, 9 | A |
| It provides a general understanding of physiological mechanisms, structure-function relationships in the cell membrane, and basic principles of cell mechanics. | 14, 16, 9 | A |
| Learns about scientific research, its general principles and methods, and how to access scientific information. | 10, 12, 13, 14, 19, 23, 9 | A |
| Learns the fundamental concepts and methods of biophysics. | 14, 16, 9 | A |
| Can describe the chemical reactions in the cell at the molecular level and explain the changes that occur in these reactions in pathological conditions. | 12, 17, 9 | A, D |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 13: Case Study Method, 14: Self Study Method, 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 23: Concept Map Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Medical Biology and Genetics: Basic structure and functions of proteins, Genetic material of the cell, DNA, chromosomes and genome, DNA replication, repair and recombination, Transfer of genetic information from DNA to protein, Control mechanisms of gene expression and cellular genetic switches, Advanced molecular techniques, Molecular fundamental biology and clinical applications of techniques | |
| 2 | Physiology: An overview of physiology, including definitions and applications. Functions of the cell membrane,Transport of substances across the cell membrane, Cell volume regulation, Mechanics of the cell | |
| 3 | Principles of Scientific Research and Access to Information: Definition and principles of scientific research, Types and stages of scientific research, Definition of scientific publication, Types of scientific publication, Access to electronic data sources, Scientific data analysis | |
| 4 | Biophysics: Physics and its branches, physical quantities, SI unit system and general equations, Introduction to biophysics, definition of biophysics, differences and common points between physics and biophysics | |
| 5 | Organic Chemistry: Alkyl halides, nucleophilic substitution reactions, organic compounds containing CO and CS, Acidity-basicity, carboxylic acids, organic compounds containing C=O, organic compounds containing N, Aromatic compounds, Biomolecules: carbohydrates, lipids, Biomolecules: amino acids, peptides, Biomolecules: proteins and enzymes, enzyme kinetics | |
| 6 | Biochemistry: the molecular meaning of life |
| Resources |
| 1. Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter “Essential Cell Biology” Fourth Edition, Garland Science Publishers, USA, 2013 2. Nesrin Emekli, Temel ve Uygulamalı Biyokimya 3. Guyton, Tıbbi Fizyoloji 4. Zeynel Dinler, Bilimsel Araştırma ve E- Kaynaklar 5. Roland Glaser, Biophysics 6. Paula Y. Bruice. Organic Chemistry 7. ed., Pearson, 2013. ISBN: 10-0-321-69768-5 |
| Course presentations and notes |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | ||||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | ||||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | ||||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | ||||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | ||||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | ||||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | ||||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | ||||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | ||||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | ||||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | ||||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | ||||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | ||||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | ||||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |