Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHYSIOPATHOLOGY | - | Yearly | 54+0 | - | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assoc.Prof. Ali Timuçin ATAYOĞLU |
| Name of Lecturer(s) | Assoc.Prof. Ali Timuçin ATAYOĞLU, Lect.Dr. Zeyneb TUZCU |
| Assistant(s) | |
| Aim | To have a knowledge about the structures and functions of the different organ system, to understand the basic function of the organ systems and to have knowledge about the common diseases related to the nervous system with a multidisciplinary point of view. |
| Course Content | This course contains; Pathophysiology of the musculoskeletal system: Bone development and function. Cell types in bone. Osteogenesis imperfecta. Achondroplasia. Osteopetrosis. Osteoporosis. Osteomalasia. Rickets. Hyperparathyroidism. Pagets disease. Fracture, development, types, complications and repair. Avascular necrosis. Osteomyelitis. Bone tumors. ,Pathophysiology of the musculoskeletal system: Osteoarthritis. Arthritis. Gout. Septic arthritis. Rheumatoid arthritis. ,Pathophysiology of the musculoskeletal system: synovial sarcoma. Ganglion. Synovial cyst. Muscle atrophy and dystrophy. Becker and Duchenne. Dystrophia myotonica. Myasthenia gravis. Myositis. ,Pathophysiology of the musculoskeletal system: Rhabdomyosarcoma. Ehler Danlos syndromes. Marfan syndrome. ,Pathophysiology of the musculoskeletal system: Soft tissue tumors. Fibromatosis. Fibrosarcoma. Leiomyoma, leiomyosarcoma, Fibrous histocytoma. ,Pathophysiology of the nervous system: Purpose of the nervous Primary motor cortex. Corticospinal tract. Lower motor neuron and skeletal muscle. Nerve roots, plexi and peripheral nerves. Lowor motor neuron reflexes. Difference between upper- and lower motor neuron damage. ALS. ,Pathophysiology of the nervous system: Somatosensory system. Dorsal column/medial leminiscus tract. Anteriolateral-/spinothalamic tract. Sensory loss. Pain pathways. Mechanisms of neuropathic pain. Dermatomes. Referred pain/visceral pain. ,Pathophysiology of the nervous system: cerebrovascular disease. Blood supply to the brain/autoregulation. Global cerebral ischemia. Watershed infarctions. Focal cerebral ischemia. Thrombus. Embolus. ,Pathophysiology of the nervous system: Aphasia. Dysphasia. Dysarthria. Neglect. Brochas area. Wernickes area. Stroke syndromes. Subclavian steal syndrome. Locked in syndrome. Different types of intracranial hemorrhage: intraparenchymal, subarachnoid, epidural hematoma, subdural hematoma. ,Pathophysiology of the nervous system: Extrapyramidal tracts. Parkinsonism and Parkinsons disease. Huntington disease. Dementia and Alzheimers disease. Epilepsy. Cerebellum and Ataxia. ,Pathophysiology of the nervous system: Brain trauma. Cerebral edema. Hydrocephalus. Herniations. Coup/counter coup lesions. Concussions. Diffuse Axonal injury. Laceration. CNS tumors. ,Pathophysiology of the circulatory and respiratory system: Pulmonary and systemic circulation. Vessel types. Blood flow in Vessels. Korotkoff sounds. Pressures in the different parts of the circulatory system. Systemic blood pressure. Pulse pressure. Mean Arterial Pressure. Atherosclerosis. Hypertension. ,Pathophysiology of the circulatory and respiratory systems: Aneurisms and dissections. Vasculitis, infective and non-infective. Raynaud phenomenon. Varicous veins. Deep vein thrombosis. Superior and inferior vena cava syndromes. Lymphangitis. Lymphedema. Chylosis. Arterial and venous leg ulcers. Tumors of the vascular system. ,Pathophysiology of the circulatory and respiratory systems: Basic heart anatomy and physiology. Pericardial development, anatomy and physiology. Blood supply to the heart. Contraction of the heart, pacemaker cells. Cardiac cycle in relation to pressure/time. Cardiac cycle in relation to pressure/volume. Increasing afterload/preload and contractile state as compensation. Arrythmias; brady- and tachy. ,Pathophysiology of the circulatory and respiratory systems: Heart failure; right sided/left sided. Forward/backward. Systolic/Diastolic. Frank/Starling effect. Jugular venous pressure. Valvular heart diseses; stenosis/regurgitation of mitral and aortic valve and their murmurs. ,Pathophysiology of the circulatory and respiratory systems: pericarditis. Tamponade. Coronary artery disease. Spasm of coronary arteries, atherosclerosis. Angina pectoris; stable and unstable. Myocardial infarction. Hearts energy supply. Hibernating. Stunning. Circulatory shock. ,Pathophysiology of the circulatory and respiratory systems: primary function of the respiratory system. Components of normal lung. Surfactant. Airway generation and resistance to airflow and cross-section. Lung function tests.Static properties of the lung: Elastic recoil and compliance. Dynamic properties: resistance to airflow. Equal pressure point. Ventilation/perfusion ratio; shunting and dead-space. ,Pathophysiology of the circulatory and respiratory systems: Asthma. COPD: emphysema and chronic bronchitis. Restrictive lung diseases. Pulmonary edema. ARDS. Pulmonary embolism. . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Pathophysiology | 10, 12, 14, 16, 19, 3, 4, 5, 6, 9 | A |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 3: Problem Baded Learning Model, 4: Inquiry-Based Learning, 5: Cooperative Learning, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Pathophysiology of the musculoskeletal system: Bone development and function. Cell types in bone. Osteogenesis imperfecta. Achondroplasia. Osteopetrosis. Osteoporosis. Osteomalasia. Rickets. Hyperparathyroidism. Pagets disease. Fracture, development, types, complications and repair. Avascular necrosis. Osteomyelitis. Bone tumors. | - |
| 2 | Pathophysiology of the musculoskeletal system: Osteoarthritis. Arthritis. Gout. Septic arthritis. Rheumatoid arthritis. | - |
| 3 | Pathophysiology of the musculoskeletal system: synovial sarcoma. Ganglion. Synovial cyst. Muscle atrophy and dystrophy. Becker and Duchenne. Dystrophia myotonica. Myasthenia gravis. Myositis. | |
| 4 | Pathophysiology of the musculoskeletal system: Rhabdomyosarcoma. Ehler Danlos syndromes. Marfan syndrome. | |
| 5 | Pathophysiology of the musculoskeletal system: Soft tissue tumors. Fibromatosis. Fibrosarcoma. Leiomyoma, leiomyosarcoma, Fibrous histocytoma. | |
| 6 | Pathophysiology of the nervous system: Purpose of the nervous Primary motor cortex. Corticospinal tract. Lower motor neuron and skeletal muscle. Nerve roots, plexi and peripheral nerves. Lowor motor neuron reflexes. Difference between upper- and lower motor neuron damage. ALS. | |
| 7 | Pathophysiology of the nervous system: Somatosensory system. Dorsal column/medial leminiscus tract. Anteriolateral-/spinothalamic tract. Sensory loss. Pain pathways. Mechanisms of neuropathic pain. Dermatomes. Referred pain/visceral pain. | |
| 8 | Pathophysiology of the nervous system: cerebrovascular disease. Blood supply to the brain/autoregulation. Global cerebral ischemia. Watershed infarctions. Focal cerebral ischemia. Thrombus. Embolus. | |
| 9 | Pathophysiology of the nervous system: Aphasia. Dysphasia. Dysarthria. Neglect. Brochas area. Wernickes area. Stroke syndromes. Subclavian steal syndrome. Locked in syndrome. Different types of intracranial hemorrhage: intraparenchymal, subarachnoid, epidural hematoma, subdural hematoma. | |
| 10 | Pathophysiology of the nervous system: Extrapyramidal tracts. Parkinsonism and Parkinsons disease. Huntington disease. Dementia and Alzheimers disease. Epilepsy. Cerebellum and Ataxia. | |
| 11 | Pathophysiology of the nervous system: Brain trauma. Cerebral edema. Hydrocephalus. Herniations. Coup/counter coup lesions. Concussions. Diffuse Axonal injury. Laceration. CNS tumors. | |
| 12 | Pathophysiology of the circulatory and respiratory system: Pulmonary and systemic circulation. Vessel types. Blood flow in Vessels. Korotkoff sounds. Pressures in the different parts of the circulatory system. Systemic blood pressure. Pulse pressure. Mean Arterial Pressure. Atherosclerosis. Hypertension. | |
| 13 | Pathophysiology of the circulatory and respiratory systems: Aneurisms and dissections. Vasculitis, infective and non-infective. Raynaud phenomenon. Varicous veins. Deep vein thrombosis. Superior and inferior vena cava syndromes. Lymphangitis. Lymphedema. Chylosis. Arterial and venous leg ulcers. Tumors of the vascular system. | |
| 14 | Pathophysiology of the circulatory and respiratory systems: Basic heart anatomy and physiology. Pericardial development, anatomy and physiology. Blood supply to the heart. Contraction of the heart, pacemaker cells. Cardiac cycle in relation to pressure/time. Cardiac cycle in relation to pressure/volume. Increasing afterload/preload and contractile state as compensation. Arrythmias; brady- and tachy. | |
| 15 | Pathophysiology of the circulatory and respiratory systems: Heart failure; right sided/left sided. Forward/backward. Systolic/Diastolic. Frank/Starling effect. Jugular venous pressure. Valvular heart diseses; stenosis/regurgitation of mitral and aortic valve and their murmurs. | |
| 16 | Pathophysiology of the circulatory and respiratory systems: pericarditis. Tamponade. Coronary artery disease. Spasm of coronary arteries, atherosclerosis. Angina pectoris; stable and unstable. Myocardial infarction. Hearts energy supply. Hibernating. Stunning. Circulatory shock. | |
| 17 | Pathophysiology of the circulatory and respiratory systems: primary function of the respiratory system. Components of normal lung. Surfactant. Airway generation and resistance to airflow and cross-section. Lung function tests.Static properties of the lung: Elastic recoil and compliance. Dynamic properties: resistance to airflow. Equal pressure point. Ventilation/perfusion ratio; shunting and dead-space. | |
| 18 | Pathophysiology of the circulatory and respiratory systems: Asthma. COPD: emphysema and chronic bronchitis. Restrictive lung diseases. Pulmonary edema. ARDS. Pulmonary embolism. |
| Resources |
| Clinical neuroanatomy. Snell, Richard S. Lippincott Williams & Wilkins, 2010. Gray's clinical neuroanatomyMancall, Elliott L., and David G. Brock. . Elsevier Health Sciences, 2011. Pathophysiology: Concepts of Altered Health States - Carol Mattson Porth Essential Concepts in Molecular Pathology - William B. Coleman Pathophysiology - FUunctional Alterations in Human Health, Carie A. Braun..Tıbbi Fizyoloji – Guyton, Ganong’s Review of Medical Physiology, Molecular Biology of the cell – Alberts, Principles of Neural Science.......Biyofizik, Ferit Pehlivan, Hacettepe Taş Kitapevi. Nörobiyofizik, Ferhan Esen-Hamza Esen, Ankara Nobel Tıp Kitapevi, Biopysics Roland Glaser.....Gartner L.P., Hiatt J.L.: Color Text Book of Histology. Second ed. SAUNDERS. Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Sadler T.W: Langman's Medical Embryology, Eleventh Edition. Lippincott Williams & Wilkins, USA Schoenwolf G.C.: Larsen’s Human Embryology. 4. Ed. CHURCHILL LIVINGSTONE ELSEVIER Stevens A., Human Histology, Third Ed. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Power Point slides |
| Medical Physiology – Guyton Ganong’s Review of Medical Physiology Molecular Biology of the cell - Alberts Principles of Neurological Sciences - Kandel Color Atlas of Physiology Color Atlas of Pathophysiology -Moore K, AF. Dalley: Clinically oriented anatomy. Seventh ed. Lippincot Williams &Wilkins Company, Philadelphia, 2013- Drake, Richard, A. Wayne Vogl, and Adam WM Mitchell. Gray's anatomy for students. Elsevier Health Sciences, 2014. -Netter FH. Atlas of human anatomy (second edition). USA, Novartis, 1997: 268. -Putz R, Pabst R. Sobotta atlas of human anatomy Volume 2 12th English Ed. Munich, Urban & Schwarzenberg 1994: 165. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Pathophysiology: Concepts of Altered Health States - Carol Mattson Porth 2. Essential Concepts in Molecular Pathology - William B. Coleman 3. Pathophysiology - FUunctional Alterations in Human Health, Carie A. Braun 4. Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty, 6th ed. Leonard S. Lilly (ed). Wolters Kluver, 2016. 5. Guyton and Hall Textbook of Medical Physiology, 13th ed. John E. Hall (ed). Elsevier, 2016. Power Point slides |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | ||||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | ||||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | ||||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | ||||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | ||||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | ||||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | ||||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | ||||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | ||||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | ||||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | ||||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | ||||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | ||||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | ||||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 0 | 0 | 0 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 0 | 0 | 0 | |||
| General Exam | 0 | 0 | 0 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 0 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(0/30) | 0 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHYSIOPATHOLOGY | - | Yearly | 54+0 | - | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assoc.Prof. Ali Timuçin ATAYOĞLU |
| Name of Lecturer(s) | Assoc.Prof. Ali Timuçin ATAYOĞLU, Lect.Dr. Zeyneb TUZCU |
| Assistant(s) | |
| Aim | To have a knowledge about the structures and functions of the different organ system, to understand the basic function of the organ systems and to have knowledge about the common diseases related to the nervous system with a multidisciplinary point of view. |
| Course Content | This course contains; Pathophysiology of the musculoskeletal system: Bone development and function. Cell types in bone. Osteogenesis imperfecta. Achondroplasia. Osteopetrosis. Osteoporosis. Osteomalasia. Rickets. Hyperparathyroidism. Pagets disease. Fracture, development, types, complications and repair. Avascular necrosis. Osteomyelitis. Bone tumors. ,Pathophysiology of the musculoskeletal system: Osteoarthritis. Arthritis. Gout. Septic arthritis. Rheumatoid arthritis. ,Pathophysiology of the musculoskeletal system: synovial sarcoma. Ganglion. Synovial cyst. Muscle atrophy and dystrophy. Becker and Duchenne. Dystrophia myotonica. Myasthenia gravis. Myositis. ,Pathophysiology of the musculoskeletal system: Rhabdomyosarcoma. Ehler Danlos syndromes. Marfan syndrome. ,Pathophysiology of the musculoskeletal system: Soft tissue tumors. Fibromatosis. Fibrosarcoma. Leiomyoma, leiomyosarcoma, Fibrous histocytoma. ,Pathophysiology of the nervous system: Purpose of the nervous Primary motor cortex. Corticospinal tract. Lower motor neuron and skeletal muscle. Nerve roots, plexi and peripheral nerves. Lowor motor neuron reflexes. Difference between upper- and lower motor neuron damage. ALS. ,Pathophysiology of the nervous system: Somatosensory system. Dorsal column/medial leminiscus tract. Anteriolateral-/spinothalamic tract. Sensory loss. Pain pathways. Mechanisms of neuropathic pain. Dermatomes. Referred pain/visceral pain. ,Pathophysiology of the nervous system: cerebrovascular disease. Blood supply to the brain/autoregulation. Global cerebral ischemia. Watershed infarctions. Focal cerebral ischemia. Thrombus. Embolus. ,Pathophysiology of the nervous system: Aphasia. Dysphasia. Dysarthria. Neglect. Brochas area. Wernickes area. Stroke syndromes. Subclavian steal syndrome. Locked in syndrome. Different types of intracranial hemorrhage: intraparenchymal, subarachnoid, epidural hematoma, subdural hematoma. ,Pathophysiology of the nervous system: Extrapyramidal tracts. Parkinsonism and Parkinsons disease. Huntington disease. Dementia and Alzheimers disease. Epilepsy. Cerebellum and Ataxia. ,Pathophysiology of the nervous system: Brain trauma. Cerebral edema. Hydrocephalus. Herniations. Coup/counter coup lesions. Concussions. Diffuse Axonal injury. Laceration. CNS tumors. ,Pathophysiology of the circulatory and respiratory system: Pulmonary and systemic circulation. Vessel types. Blood flow in Vessels. Korotkoff sounds. Pressures in the different parts of the circulatory system. Systemic blood pressure. Pulse pressure. Mean Arterial Pressure. Atherosclerosis. Hypertension. ,Pathophysiology of the circulatory and respiratory systems: Aneurisms and dissections. Vasculitis, infective and non-infective. Raynaud phenomenon. Varicous veins. Deep vein thrombosis. Superior and inferior vena cava syndromes. Lymphangitis. Lymphedema. Chylosis. Arterial and venous leg ulcers. Tumors of the vascular system. ,Pathophysiology of the circulatory and respiratory systems: Basic heart anatomy and physiology. Pericardial development, anatomy and physiology. Blood supply to the heart. Contraction of the heart, pacemaker cells. Cardiac cycle in relation to pressure/time. Cardiac cycle in relation to pressure/volume. Increasing afterload/preload and contractile state as compensation. Arrythmias; brady- and tachy. ,Pathophysiology of the circulatory and respiratory systems: Heart failure; right sided/left sided. Forward/backward. Systolic/Diastolic. Frank/Starling effect. Jugular venous pressure. Valvular heart diseses; stenosis/regurgitation of mitral and aortic valve and their murmurs. ,Pathophysiology of the circulatory and respiratory systems: pericarditis. Tamponade. Coronary artery disease. Spasm of coronary arteries, atherosclerosis. Angina pectoris; stable and unstable. Myocardial infarction. Hearts energy supply. Hibernating. Stunning. Circulatory shock. ,Pathophysiology of the circulatory and respiratory systems: primary function of the respiratory system. Components of normal lung. Surfactant. Airway generation and resistance to airflow and cross-section. Lung function tests.Static properties of the lung: Elastic recoil and compliance. Dynamic properties: resistance to airflow. Equal pressure point. Ventilation/perfusion ratio; shunting and dead-space. ,Pathophysiology of the circulatory and respiratory systems: Asthma. COPD: emphysema and chronic bronchitis. Restrictive lung diseases. Pulmonary edema. ARDS. Pulmonary embolism. . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Pathophysiology | 10, 12, 14, 16, 19, 3, 4, 5, 6, 9 | A |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 14: Self Study Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 3: Problem Baded Learning Model, 4: Inquiry-Based Learning, 5: Cooperative Learning, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Pathophysiology of the musculoskeletal system: Bone development and function. Cell types in bone. Osteogenesis imperfecta. Achondroplasia. Osteopetrosis. Osteoporosis. Osteomalasia. Rickets. Hyperparathyroidism. Pagets disease. Fracture, development, types, complications and repair. Avascular necrosis. Osteomyelitis. Bone tumors. | - |
| 2 | Pathophysiology of the musculoskeletal system: Osteoarthritis. Arthritis. Gout. Septic arthritis. Rheumatoid arthritis. | - |
| 3 | Pathophysiology of the musculoskeletal system: synovial sarcoma. Ganglion. Synovial cyst. Muscle atrophy and dystrophy. Becker and Duchenne. Dystrophia myotonica. Myasthenia gravis. Myositis. | |
| 4 | Pathophysiology of the musculoskeletal system: Rhabdomyosarcoma. Ehler Danlos syndromes. Marfan syndrome. | |
| 5 | Pathophysiology of the musculoskeletal system: Soft tissue tumors. Fibromatosis. Fibrosarcoma. Leiomyoma, leiomyosarcoma, Fibrous histocytoma. | |
| 6 | Pathophysiology of the nervous system: Purpose of the nervous Primary motor cortex. Corticospinal tract. Lower motor neuron and skeletal muscle. Nerve roots, plexi and peripheral nerves. Lowor motor neuron reflexes. Difference between upper- and lower motor neuron damage. ALS. | |
| 7 | Pathophysiology of the nervous system: Somatosensory system. Dorsal column/medial leminiscus tract. Anteriolateral-/spinothalamic tract. Sensory loss. Pain pathways. Mechanisms of neuropathic pain. Dermatomes. Referred pain/visceral pain. | |
| 8 | Pathophysiology of the nervous system: cerebrovascular disease. Blood supply to the brain/autoregulation. Global cerebral ischemia. Watershed infarctions. Focal cerebral ischemia. Thrombus. Embolus. | |
| 9 | Pathophysiology of the nervous system: Aphasia. Dysphasia. Dysarthria. Neglect. Brochas area. Wernickes area. Stroke syndromes. Subclavian steal syndrome. Locked in syndrome. Different types of intracranial hemorrhage: intraparenchymal, subarachnoid, epidural hematoma, subdural hematoma. | |
| 10 | Pathophysiology of the nervous system: Extrapyramidal tracts. Parkinsonism and Parkinsons disease. Huntington disease. Dementia and Alzheimers disease. Epilepsy. Cerebellum and Ataxia. | |
| 11 | Pathophysiology of the nervous system: Brain trauma. Cerebral edema. Hydrocephalus. Herniations. Coup/counter coup lesions. Concussions. Diffuse Axonal injury. Laceration. CNS tumors. | |
| 12 | Pathophysiology of the circulatory and respiratory system: Pulmonary and systemic circulation. Vessel types. Blood flow in Vessels. Korotkoff sounds. Pressures in the different parts of the circulatory system. Systemic blood pressure. Pulse pressure. Mean Arterial Pressure. Atherosclerosis. Hypertension. | |
| 13 | Pathophysiology of the circulatory and respiratory systems: Aneurisms and dissections. Vasculitis, infective and non-infective. Raynaud phenomenon. Varicous veins. Deep vein thrombosis. Superior and inferior vena cava syndromes. Lymphangitis. Lymphedema. Chylosis. Arterial and venous leg ulcers. Tumors of the vascular system. | |
| 14 | Pathophysiology of the circulatory and respiratory systems: Basic heart anatomy and physiology. Pericardial development, anatomy and physiology. Blood supply to the heart. Contraction of the heart, pacemaker cells. Cardiac cycle in relation to pressure/time. Cardiac cycle in relation to pressure/volume. Increasing afterload/preload and contractile state as compensation. Arrythmias; brady- and tachy. | |
| 15 | Pathophysiology of the circulatory and respiratory systems: Heart failure; right sided/left sided. Forward/backward. Systolic/Diastolic. Frank/Starling effect. Jugular venous pressure. Valvular heart diseses; stenosis/regurgitation of mitral and aortic valve and their murmurs. | |
| 16 | Pathophysiology of the circulatory and respiratory systems: pericarditis. Tamponade. Coronary artery disease. Spasm of coronary arteries, atherosclerosis. Angina pectoris; stable and unstable. Myocardial infarction. Hearts energy supply. Hibernating. Stunning. Circulatory shock. | |
| 17 | Pathophysiology of the circulatory and respiratory systems: primary function of the respiratory system. Components of normal lung. Surfactant. Airway generation and resistance to airflow and cross-section. Lung function tests.Static properties of the lung: Elastic recoil and compliance. Dynamic properties: resistance to airflow. Equal pressure point. Ventilation/perfusion ratio; shunting and dead-space. | |
| 18 | Pathophysiology of the circulatory and respiratory systems: Asthma. COPD: emphysema and chronic bronchitis. Restrictive lung diseases. Pulmonary edema. ARDS. Pulmonary embolism. |
| Resources |
| Clinical neuroanatomy. Snell, Richard S. Lippincott Williams & Wilkins, 2010. Gray's clinical neuroanatomyMancall, Elliott L., and David G. Brock. . Elsevier Health Sciences, 2011. Pathophysiology: Concepts of Altered Health States - Carol Mattson Porth Essential Concepts in Molecular Pathology - William B. Coleman Pathophysiology - FUunctional Alterations in Human Health, Carie A. Braun..Tıbbi Fizyoloji – Guyton, Ganong’s Review of Medical Physiology, Molecular Biology of the cell – Alberts, Principles of Neural Science.......Biyofizik, Ferit Pehlivan, Hacettepe Taş Kitapevi. Nörobiyofizik, Ferhan Esen-Hamza Esen, Ankara Nobel Tıp Kitapevi, Biopysics Roland Glaser.....Gartner L.P., Hiatt J.L.: Color Text Book of Histology. Second ed. SAUNDERS. Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Sadler T.W: Langman's Medical Embryology, Eleventh Edition. Lippincott Williams & Wilkins, USA Schoenwolf G.C.: Larsen’s Human Embryology. 4. Ed. CHURCHILL LIVINGSTONE ELSEVIER Stevens A., Human Histology, Third Ed. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Power Point slides |
| Medical Physiology – Guyton Ganong’s Review of Medical Physiology Molecular Biology of the cell - Alberts Principles of Neurological Sciences - Kandel Color Atlas of Physiology Color Atlas of Pathophysiology -Moore K, AF. Dalley: Clinically oriented anatomy. Seventh ed. Lippincot Williams &Wilkins Company, Philadelphia, 2013- Drake, Richard, A. Wayne Vogl, and Adam WM Mitchell. Gray's anatomy for students. Elsevier Health Sciences, 2014. -Netter FH. Atlas of human anatomy (second edition). USA, Novartis, 1997: 268. -Putz R, Pabst R. Sobotta atlas of human anatomy Volume 2 12th English Ed. Munich, Urban & Schwarzenberg 1994: 165. Junqueira L.C., Carneiro J. Çev. Ed: Aytekin Y, Solakoğlu S.: Temel Histoloji. NOBEL TIP Gartner L.P., Hiatt J.L.: Color Atlas of Histology, Fifth Edition. Lippincott Williams & Wilkins, USA Welsch U. Çev. Ed.: Tekelioğlu M.: Sobotta Histoloji Atlası. BETA Moore K.M., Persaud T.V.N. Çev. Ed: Yıldırım M., Okar İ., Dalçık H. Klinik Yönleri ile İnsan Embriyolojisi. 6. Ed. NOBEL TIP Pathophysiology: Concepts of Altered Health States - Carol Mattson Porth 2. Essential Concepts in Molecular Pathology - William B. Coleman 3. Pathophysiology - FUunctional Alterations in Human Health, Carie A. Braun 4. Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty, 6th ed. Leonard S. Lilly (ed). Wolters Kluver, 2016. 5. Guyton and Hall Textbook of Medical Physiology, 13th ed. John E. Hall (ed). Elsevier, 2016. Power Point slides |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | ||||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | ||||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | ||||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | ||||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | ||||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | ||||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | ||||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | ||||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | ||||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | ||||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | ||||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | ||||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | ||||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | ||||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |