Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ADVANCED MICROSCOPIC PRINCIPLES | - | Fall Semester | 2+4 | 4 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. İlknur KESKİN |
| Name of Lecturer(s) | Prof.Dr. İlknur KESKİN |
| Assistant(s) | |
| Aim | The aim of this course is to teach the optical and electronic designs of microscopes and imaging techniques by choosing the appropriate microscope in experimental studies. |
| Course Content | This course contains; Microscope basics,Light and color,Lighting, filtering and display tools,Geometric optical design,Diffraction and interference,Bright-field, phase-contrast, and dark-field imaging,MIDTERM WEEK,polarized microscopy,fluorescent microscopy,Scanning confocal microscopy,Advanced microscopy techniques,New microscopy techniques,Image processing for microscopy,Final exam. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Defines the optical elements and sensors used in light microscope optical design. | 9 | A, E |
| Defines the basic terms of diffraction and reflection used in microscopes. | 14, 9 | A, E |
| Explains the working principle of the fluorescence microscope. | 17, 6, 9 | A |
| Evaluates patents/articles describing advanced microscope techniques. | 9 | A, E |
| Explains the working principle of polarizing microscope. | 14, 9 | A, E |
| Explains the working principle of confocal microscopy. | 14, 17, 6, 9 | A |
| Explains the working principle of the dark field microscope. | 14, 9 | A, E |
| Explains the working principle of phase contrast microscope. | 17, 6, 9 | A |
| Defines the concept of optical resolution. | 14, 9 | A, E |
| Explains the working principle of bright field microscope. | 14, 9 | A |
| Teaching Methods: | 14: Self Study Method, 17: Experimental Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Microscope basics | Reading the relevant course presentation |
| 2 | Light and color | Reading the relevant course presentation |
| 3 | Lighting, filtering and display tools | Reading the relevant course presentation |
| 4 | Geometric optical design | Reading the relevant course presentation |
| 5 | Diffraction and interference | Reading the relevant course presentation |
| 6 | Bright-field, phase-contrast, and dark-field imaging | Microscopy from A to Z in Life Sciences. Alp Can. Reading page: 87-107. |
| 7 | MIDTERM WEEK | |
| 8 | polarized microscopy | Microscopy from A to Z in Life Sciences .Alp Can. Reading page:108-113. |
| 9 | fluorescent microscopy | Microscopy from A to Z in Life Sciences .Alp Can. Reading page:129-149. |
| 10 | Scanning confocal microscopy | Reading the relevant course presentation |
| 11 | Advanced microscopy techniques | Reading the relevant course presentation |
| 12 | New microscopy techniques | Reading the relevant course presentation |
| 13 | Image processing for microscopy | Reading the relevant course presentation |
| 14 | Final exam |
| Resources |
| Microscopy in Life Sciences from A to Z- Alp Can- Nobel Tıp Kitabevleri, lecture notes |
| Fundamentals of light microscopy and electronic imaging, D.B. Murphyö Willey 2001 Optical nanoscopy and novel microscopy techniques, P.Xi, CRC Press, 2014 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Develops and deepens current and advanced knowledge in the field of histology with original thought and research at the level of expertise and reaches original definitions that will bring innovation to the field. | X | |||||
| 2 | Defines cell and tissue at an advanced level (ultrastructural). | X | |||||
| 3 | Knows the embryological details about the development of systems at an advanced level. | ||||||
| 4 | Comprehends the interdisciplinary interaction that the field is related to; reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | X | |||||
| 5 | Develops a new idea, method, design or application that brings innovation to the field, or applies a known idea, method, design or application to a different field, researches, comprehends, designs, adapts and applies an original subject. | X | |||||
| 6 | He/she writes the report of the research he/she participated in. It publishes in a national/internationally accepted peer-reviewed journal and presents it at scientific meetings. | ||||||
| 7 | It contributes to the progress in its field by independently carrying out an original work that brings innovations to its field, develops a new idea, method, design or application, or applies a known idea, method, design or application to a different field. | ||||||
| 8 | Develops new thoughts and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. | ||||||
| 9 | Participates in meetings related to the field of histology, presents papers, participates in discussions, gives conferences, and publishes his studies in reputable journals specific to the field. | ||||||
| 10 | Collects, interprets, applies and announces data related to histology and embryology. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 5 | 70 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 6 | 15 | 90 | |||
| Term Project | 3 | 10 | 30 | |||
| Presentation of Project / Seminar | 2 | 10 | 20 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 15 | 15 | |||
| General Exam | 1 | 15 | 15 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 240 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(240/30) | 8 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| ADVANCED MICROSCOPIC PRINCIPLES | - | Fall Semester | 2+4 | 4 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Third Cycle (Doctorate Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. İlknur KESKİN |
| Name of Lecturer(s) | Prof.Dr. İlknur KESKİN |
| Assistant(s) | |
| Aim | The aim of this course is to teach the optical and electronic designs of microscopes and imaging techniques by choosing the appropriate microscope in experimental studies. |
| Course Content | This course contains; Microscope basics,Light and color,Lighting, filtering and display tools,Geometric optical design,Diffraction and interference,Bright-field, phase-contrast, and dark-field imaging,MIDTERM WEEK,polarized microscopy,fluorescent microscopy,Scanning confocal microscopy,Advanced microscopy techniques,New microscopy techniques,Image processing for microscopy,Final exam. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Defines the optical elements and sensors used in light microscope optical design. | 9 | A, E |
| Defines the basic terms of diffraction and reflection used in microscopes. | 14, 9 | A, E |
| Explains the working principle of the fluorescence microscope. | 17, 6, 9 | A |
| Evaluates patents/articles describing advanced microscope techniques. | 9 | A, E |
| Explains the working principle of polarizing microscope. | 14, 9 | A, E |
| Explains the working principle of confocal microscopy. | 14, 17, 6, 9 | A |
| Explains the working principle of the dark field microscope. | 14, 9 | A, E |
| Explains the working principle of phase contrast microscope. | 17, 6, 9 | A |
| Defines the concept of optical resolution. | 14, 9 | A, E |
| Explains the working principle of bright field microscope. | 14, 9 | A |
| Teaching Methods: | 14: Self Study Method, 17: Experimental Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Microscope basics | Reading the relevant course presentation |
| 2 | Light and color | Reading the relevant course presentation |
| 3 | Lighting, filtering and display tools | Reading the relevant course presentation |
| 4 | Geometric optical design | Reading the relevant course presentation |
| 5 | Diffraction and interference | Reading the relevant course presentation |
| 6 | Bright-field, phase-contrast, and dark-field imaging | Microscopy from A to Z in Life Sciences. Alp Can. Reading page: 87-107. |
| 7 | MIDTERM WEEK | |
| 8 | polarized microscopy | Microscopy from A to Z in Life Sciences .Alp Can. Reading page:108-113. |
| 9 | fluorescent microscopy | Microscopy from A to Z in Life Sciences .Alp Can. Reading page:129-149. |
| 10 | Scanning confocal microscopy | Reading the relevant course presentation |
| 11 | Advanced microscopy techniques | Reading the relevant course presentation |
| 12 | New microscopy techniques | Reading the relevant course presentation |
| 13 | Image processing for microscopy | Reading the relevant course presentation |
| 14 | Final exam |
| Resources |
| Microscopy in Life Sciences from A to Z- Alp Can- Nobel Tıp Kitabevleri, lecture notes |
| Fundamentals of light microscopy and electronic imaging, D.B. Murphyö Willey 2001 Optical nanoscopy and novel microscopy techniques, P.Xi, CRC Press, 2014 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Develops and deepens current and advanced knowledge in the field of histology with original thought and research at the level of expertise and reaches original definitions that will bring innovation to the field. | X | |||||
| 2 | Defines cell and tissue at an advanced level (ultrastructural). | X | |||||
| 3 | Knows the embryological details about the development of systems at an advanced level. | ||||||
| 4 | Comprehends the interdisciplinary interaction that the field is related to; reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | X | |||||
| 5 | Develops a new idea, method, design or application that brings innovation to the field, or applies a known idea, method, design or application to a different field, researches, comprehends, designs, adapts and applies an original subject. | X | |||||
| 6 | He/she writes the report of the research he/she participated in. It publishes in a national/internationally accepted peer-reviewed journal and presents it at scientific meetings. | ||||||
| 7 | It contributes to the progress in its field by independently carrying out an original work that brings innovations to its field, develops a new idea, method, design or application, or applies a known idea, method, design or application to a different field. | ||||||
| 8 | Develops new thoughts and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. | ||||||
| 9 | Participates in meetings related to the field of histology, presents papers, participates in discussions, gives conferences, and publishes his studies in reputable journals specific to the field. | ||||||
| 10 | Collects, interprets, applies and announces data related to histology and embryology. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |