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Course Description

CourseCodeSemesterT+P (Hour)CreditECTS
RESEARCH TECHNIQUES in BIOCHEMISTY II-Spring Semester2+236
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of CourseTurkish
Course LevelThird Cycle (Doctorate Degree)
Course TypeElective
Course Coordinator
Name of Lecturer(s)Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Gözde ÜLFER, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI
Assistant(s)
AimDetailed information about the methods and devices used in biochemical research
Course ContentThis course contains; Creative thinking and research ethics in basic health sciences,National, international studies and resources on the production and transmission of information,Preparation of scientific publications and project examples and protection of the right of intellectual property,Methods of panda and cell purification,Electrophoresis differentiation methods (I),Electrophoresis differentiation methods (II),Chromotographic methods according to separation mechanisms (I),Chromotographic methods according to separation methods (II),Immunological methods,Immunohistochemical differentiation methods,Radioactive labeled immunological methods,Methods of protein separation by chemical methods,Methods of separation and measurement of lipids by chemical methods,Quality management in laboratories.
Dersin Öğrenme KazanımlarıTeaching MethodsAssessment Methods
1-Evaluate creative thinking and research ethics in biochemistry and basic health sciences10, 11, 16, 19, 6, 9A, D, E
1.1Analyze creative thinking about vital events in and out of the cell10, 11, 16, 19, 6, 9A, D, E
3-To prepare the scientific publications and project examples and to know explains the legislation on the protection of the right of intellectual property10, 11, 16, 19, 6, 9A, D, E
3.1.Abstract, introduction and purpose in the scientific publication, methods used, explains and rules that should be considered in the discussion10, 11, 16, 19, 6, 9A, D, E
3.2.Provides national and international project support applications10, 11, 16, 19, 6, 9A, D, E
3.3.Explain the concept of protection of copyrights, copyright, patent10, 11, 16, 19, 6, 9A, D, E
4-Apply the methods of purification and cell purification10, 11, 16, 19, 6, 9A, D, E
4.1.Applies to preparative and analytical purification methods of enzymes and proteins10, 11, 16, 19, 6, 9A, D, E
4.3.Excraction, precipitation, definition of separation rules in ultracentrifuge10, 11, 16, 19, 6, 9A, D, E
4.4.Explains how to make molecules of various sizes in dialysis10, 11, 16, 19, 6, 9A, D, E
4.5.What conditions will the molecule be stored in question?10, 11, 16, 19, 6, 9A, D, E
5-Discuss electrophoretic separation methods10, 11, 16, 19, 6, 9A, D, E
5.1.Explains Electrophoresis varieties10, 11, 16, 19, 6, 9A, D, E
6-Explains chromatographic separation methods10, 11, 16, 19, 6, 9A, D, E
6.1.Discuss the difference between several chromatographic methods10, 11, 16, 19, 6, 9A, D, E
7-Immunological and immunohistochemical methods questions10, 11, 16, 19, 6, 9A, D, E
7.1.Inquire the principles of immunelectrophoresis10, 11, 16, 19, 6, 9A, D, E
7.2.Analyze various types of immunoelectrophoresis10, 11, 16, 19, 6, 9A, D, E
7.3.Explains Immunohistochemical methods used in body fluids10, 11, 16, 19, 6, 9A, D, E
7.4.Discuss the use of immunohistochemical methods in diagnosis and treatment, may develop creative ideas10, 11, 16, 19, 6, 9A, D, E
8-Analyzes the various differentiation methods related to macromolecules10, 11, 16, 19, 6, 9A, D, E
8.1.Analyze chemical separation methods related to proteins10, 11, 16, 19, 6, 9A, D, E
8.2.Analyze the chemical separation methods related to nucleic acids10, 11, 16, 19, 6, 9A, D, E
8.3.Analyze chemical separation methods related to lipids10, 11, 16, 19, 6, 9A, D, E
8.4.Describe chemical separation methods related to carbohydrates10, 11, 16, 19, 6, 9A, D, E
9-Questions about laboratory quality management10, 11, 16, 19, 6, 9A, D, E
9.1.Explains labor quality management performance evaluation criteria 10, 11, 16, 19, 6, 9A, D, E
9.2.Questions the requirements for laboratory security10, 11, 16, 19, 6, 9A, D, E
1.2. Establishes technology relationship with creative thinking10, 11, 16, 6, 9A, D, E
1.3. Define research ethics and apply them10, 11, 16, 19, 6, 9A, D, E
2. Describe national, international studies and resources related to the production and transmission of information10, 11, 16, 19, 6, 9A, D, E
2.1. Bologna Process, Lisbon strategy, opens Oslo declaration10, 11, 16, 19, 6, 9A, D, E
2.2. Analyzes the effects of this declaration and strategies on innovation in our country10, 11, 16, 19, 6, 9A, D, E
2.3. It makes brainstorming about innovation in the field of biochemistry which is the most basic scientific area of ​​life10, 11, 16, 19, 6, 9A, D, E
2.4. Explain national and international resources for scientific project10, 11, 16, 19, 6, 9A, D, E
2.4.1. The European Union recognizes its support10, 11, 16, 19, 6, 9A, D, E
2.4.2. ARDEP, BİDEB .. knows about TÜBİTAK and Industry supports10, 11, 16, 19, 6, 9A, D, E
4.2 Questions about which way to follow for transportation10, 11, 16, 19, 6, 9A, D, E
5.2 Electrophoresis sample loading implements dyeing and imaging10, 11, 16, 19, 6, 9A, D, E
5.3. Questions Isoelectric focusing in electrophoresis10, 11, 16, 19, 6, 9A, D, E
5.4. Applying two dimensional electrophoresis10, 11, 16, 19, 6, 9A, D, E
5.5. Brainstorming for creative thinking in electrophoretic practice10, 11, 16, 19, 6, 9A, D, E
6.2. Describe the difference according to phase types in chromatographical analyzes10, 11, 16, 19, 6, 9A, D, E
6.3. Brainstorming for creativity in chromatographical analyzes10, 11, 16, 19, 6, 9A, D, E
7.5. Explains the radioactive labeled immunoassays10, 11, 16, 19, 6, 9A, D, E
8.5. Apply creative ideas when applying these methods10, 11, 16, 19, 6, 9A, D, E
9.3. Questions Test performance competence questions10, 11, 16, 19, 6, 9A, D, E
Teaching Methods:10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method
Assessment Methods:A: Traditional Written Exam, D: Oral Exam, E: Homework

Course Outline

OrderSubjectsPreliminary Work
1Creative thinking and research ethics in basic health sciences1,2,3,4,5,6,7,8,9,10
2National, international studies and resources on the production and transmission of information1,2,3,4,5,6,7,8,9,10
3Preparation of scientific publications and project examples and protection of the right of intellectual property1,2,3,4,5,6,7,8,9,10
4Methods of panda and cell purification1,2,3,4,5,6,7,8,9,10
5Electrophoresis differentiation methods (I)1,2,3,4,5,6,7,8,9,10
6Electrophoresis differentiation methods (II)1,2,3,4,5,6,7,8,9,10
7Chromotographic methods according to separation mechanisms (I)1,2,3,4,5,6,7,8,9,10
8Chromotographic methods according to separation methods (II)1,2,3,4,5,6,7,8,9,10
9Immunological methods1,2,3,4,5,6,7,8,9,10
10Immunohistochemical differentiation methods1,2,3,4,5,6,7,8,9,10
11Radioactive labeled immunological methods1,2,3,4,5,6,7,8,9,10
12Methods of protein separation by chemical methods1,2,3,4,5,6,7,8,9,10
13Methods of separation and measurement of lipids by chemical methods1,2,3,4,5,6,7,8,9,10
14Quality management in laboratories1,2,3,4,5,6,7,8,9,10
Resources
1) Clinical Chemistry Techniques,Prınciples,Correlations(M.Bishop,Fody E,Schoeff LE) 2) Clinical chemistry ; Theory , analysis , correlation ed.Lawrence A.Kaplan, Amadeo J.Pesce , Mosby Elsevier 5. Baskı, 2010 3) Cryer P. The research students guide to success 4) Whimster WF. Biomedical research:How to plan, publis and presented 5) Oglen TE, Goldberg IA. Research proposal: A guide to success 6) Yalın R. Bilimsel makale nasıl yazılır ve yayınlanır? Turkish journal of surgery 24(2):100-103, 2008. 7) İmamoğlu SZ, Açıkgöz A.Milli yenilik sistemleri ve Türkiye için öneriler. Girişimcilik ve İnovasyon Yönetimi Dergisi Journal of Entrepreneurship and Innovation Management ) 1 (1): 69-96, 2012. 8) Kaynak. Ali Riza Erdem Bilimsel etik Yükseköğretim ve Bilim Dergisi 2:1:25-32,2012 9)Gülbaş SY. İnovasyon:Teknopark Modeli . ANKEM Derg 2011;25(Ek 2):139-145 10) Demir M ve Geyik O. Türkiye’de AR-GE ve inovasyon harcamalarının gelişim süreci ve ekonomik etkileri. Journal of Life Economics 2: 171-186, 2014.

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
NoProgram QualificationContribution Level
12345
1
Defines macro and micromolecules in cell and body fluids at an advanced level.
X
2
Knows how to store and protect the material to be analyzed.
X
3
Knows how to identify molecules found in cells and body fluids.
X
4
Knows the principles of technologies to be used for routine and research purposes.
X
5
Knows how to evaluate the results of the study, interprets and questions.
X
6
Knows how to use field-specific tools and equipment
X
7
Knows how to access and interpret field-specific resources and information
X
8
Shares information with disciplines related to the field
X
9
Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals.
X
10
Solves a scientific and technical problem, knows where to get help.
X
11
Takes responsibility in joint scientific studies, contributes and works in harmony.
X
12
Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field.
X
13
Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially.
X
14
Can take part in management activities, evaluate the results obtained to improve quality
X

Assessment Methods

Contribution LevelAbsolute Evaluation
Rate of Midterm Exam to Success 50
Rate of Final Exam to Success 50
Total 100
ECTS / Workload Table
ActivitiesNumber ofDuration(Hour)Total Workload(Hour)
Course Hours14228
Guided Problem Solving14456
Resolution of Homework Problems and Submission as a Report000
Term Project4520
Presentation of Project / Seminar2510
Quiz000
Midterm Exam12525
General Exam13030
Performance Task, Maintenance Plan000
Total Workload(Hour)169
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(169/30)6
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.

Detail Informations of the Course

Course Description

CourseCodeSemesterT+P (Hour)CreditECTS
RESEARCH TECHNIQUES in BIOCHEMISTY II-Spring Semester2+236
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of CourseTurkish
Course LevelThird Cycle (Doctorate Degree)
Course TypeElective
Course Coordinator
Name of Lecturer(s)Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Gözde ÜLFER, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI
Assistant(s)
AimDetailed information about the methods and devices used in biochemical research
Course ContentThis course contains; Creative thinking and research ethics in basic health sciences,National, international studies and resources on the production and transmission of information,Preparation of scientific publications and project examples and protection of the right of intellectual property,Methods of panda and cell purification,Electrophoresis differentiation methods (I),Electrophoresis differentiation methods (II),Chromotographic methods according to separation mechanisms (I),Chromotographic methods according to separation methods (II),Immunological methods,Immunohistochemical differentiation methods,Radioactive labeled immunological methods,Methods of protein separation by chemical methods,Methods of separation and measurement of lipids by chemical methods,Quality management in laboratories.
Dersin Öğrenme KazanımlarıTeaching MethodsAssessment Methods
1-Evaluate creative thinking and research ethics in biochemistry and basic health sciences10, 11, 16, 19, 6, 9A, D, E
1.1Analyze creative thinking about vital events in and out of the cell10, 11, 16, 19, 6, 9A, D, E
3-To prepare the scientific publications and project examples and to know explains the legislation on the protection of the right of intellectual property10, 11, 16, 19, 6, 9A, D, E
3.1.Abstract, introduction and purpose in the scientific publication, methods used, explains and rules that should be considered in the discussion10, 11, 16, 19, 6, 9A, D, E
3.2.Provides national and international project support applications10, 11, 16, 19, 6, 9A, D, E
3.3.Explain the concept of protection of copyrights, copyright, patent10, 11, 16, 19, 6, 9A, D, E
4-Apply the methods of purification and cell purification10, 11, 16, 19, 6, 9A, D, E
4.1.Applies to preparative and analytical purification methods of enzymes and proteins10, 11, 16, 19, 6, 9A, D, E
4.3.Excraction, precipitation, definition of separation rules in ultracentrifuge10, 11, 16, 19, 6, 9A, D, E
4.4.Explains how to make molecules of various sizes in dialysis10, 11, 16, 19, 6, 9A, D, E
4.5.What conditions will the molecule be stored in question?10, 11, 16, 19, 6, 9A, D, E
5-Discuss electrophoretic separation methods10, 11, 16, 19, 6, 9A, D, E
5.1.Explains Electrophoresis varieties10, 11, 16, 19, 6, 9A, D, E
6-Explains chromatographic separation methods10, 11, 16, 19, 6, 9A, D, E
6.1.Discuss the difference between several chromatographic methods10, 11, 16, 19, 6, 9A, D, E
7-Immunological and immunohistochemical methods questions10, 11, 16, 19, 6, 9A, D, E
7.1.Inquire the principles of immunelectrophoresis10, 11, 16, 19, 6, 9A, D, E
7.2.Analyze various types of immunoelectrophoresis10, 11, 16, 19, 6, 9A, D, E
7.3.Explains Immunohistochemical methods used in body fluids10, 11, 16, 19, 6, 9A, D, E
7.4.Discuss the use of immunohistochemical methods in diagnosis and treatment, may develop creative ideas10, 11, 16, 19, 6, 9A, D, E
8-Analyzes the various differentiation methods related to macromolecules10, 11, 16, 19, 6, 9A, D, E
8.1.Analyze chemical separation methods related to proteins10, 11, 16, 19, 6, 9A, D, E
8.2.Analyze the chemical separation methods related to nucleic acids10, 11, 16, 19, 6, 9A, D, E
8.3.Analyze chemical separation methods related to lipids10, 11, 16, 19, 6, 9A, D, E
8.4.Describe chemical separation methods related to carbohydrates10, 11, 16, 19, 6, 9A, D, E
9-Questions about laboratory quality management10, 11, 16, 19, 6, 9A, D, E
9.1.Explains labor quality management performance evaluation criteria 10, 11, 16, 19, 6, 9A, D, E
9.2.Questions the requirements for laboratory security10, 11, 16, 19, 6, 9A, D, E
1.2. Establishes technology relationship with creative thinking10, 11, 16, 6, 9A, D, E
1.3. Define research ethics and apply them10, 11, 16, 19, 6, 9A, D, E
2. Describe national, international studies and resources related to the production and transmission of information10, 11, 16, 19, 6, 9A, D, E
2.1. Bologna Process, Lisbon strategy, opens Oslo declaration10, 11, 16, 19, 6, 9A, D, E
2.2. Analyzes the effects of this declaration and strategies on innovation in our country10, 11, 16, 19, 6, 9A, D, E
2.3. It makes brainstorming about innovation in the field of biochemistry which is the most basic scientific area of ​​life10, 11, 16, 19, 6, 9A, D, E
2.4. Explain national and international resources for scientific project10, 11, 16, 19, 6, 9A, D, E
2.4.1. The European Union recognizes its support10, 11, 16, 19, 6, 9A, D, E
2.4.2. ARDEP, BİDEB .. knows about TÜBİTAK and Industry supports10, 11, 16, 19, 6, 9A, D, E
4.2 Questions about which way to follow for transportation10, 11, 16, 19, 6, 9A, D, E
5.2 Electrophoresis sample loading implements dyeing and imaging10, 11, 16, 19, 6, 9A, D, E
5.3. Questions Isoelectric focusing in electrophoresis10, 11, 16, 19, 6, 9A, D, E
5.4. Applying two dimensional electrophoresis10, 11, 16, 19, 6, 9A, D, E
5.5. Brainstorming for creative thinking in electrophoretic practice10, 11, 16, 19, 6, 9A, D, E
6.2. Describe the difference according to phase types in chromatographical analyzes10, 11, 16, 19, 6, 9A, D, E
6.3. Brainstorming for creativity in chromatographical analyzes10, 11, 16, 19, 6, 9A, D, E
7.5. Explains the radioactive labeled immunoassays10, 11, 16, 19, 6, 9A, D, E
8.5. Apply creative ideas when applying these methods10, 11, 16, 19, 6, 9A, D, E
9.3. Questions Test performance competence questions10, 11, 16, 19, 6, 9A, D, E
Teaching Methods:10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method
Assessment Methods:A: Traditional Written Exam, D: Oral Exam, E: Homework

Course Outline

OrderSubjectsPreliminary Work
1Creative thinking and research ethics in basic health sciences1,2,3,4,5,6,7,8,9,10
2National, international studies and resources on the production and transmission of information1,2,3,4,5,6,7,8,9,10
3Preparation of scientific publications and project examples and protection of the right of intellectual property1,2,3,4,5,6,7,8,9,10
4Methods of panda and cell purification1,2,3,4,5,6,7,8,9,10
5Electrophoresis differentiation methods (I)1,2,3,4,5,6,7,8,9,10
6Electrophoresis differentiation methods (II)1,2,3,4,5,6,7,8,9,10
7Chromotographic methods according to separation mechanisms (I)1,2,3,4,5,6,7,8,9,10
8Chromotographic methods according to separation methods (II)1,2,3,4,5,6,7,8,9,10
9Immunological methods1,2,3,4,5,6,7,8,9,10
10Immunohistochemical differentiation methods1,2,3,4,5,6,7,8,9,10
11Radioactive labeled immunological methods1,2,3,4,5,6,7,8,9,10
12Methods of protein separation by chemical methods1,2,3,4,5,6,7,8,9,10
13Methods of separation and measurement of lipids by chemical methods1,2,3,4,5,6,7,8,9,10
14Quality management in laboratories1,2,3,4,5,6,7,8,9,10
Resources
1) Clinical Chemistry Techniques,Prınciples,Correlations(M.Bishop,Fody E,Schoeff LE) 2) Clinical chemistry ; Theory , analysis , correlation ed.Lawrence A.Kaplan, Amadeo J.Pesce , Mosby Elsevier 5. Baskı, 2010 3) Cryer P. The research students guide to success 4) Whimster WF. Biomedical research:How to plan, publis and presented 5) Oglen TE, Goldberg IA. Research proposal: A guide to success 6) Yalın R. Bilimsel makale nasıl yazılır ve yayınlanır? Turkish journal of surgery 24(2):100-103, 2008. 7) İmamoğlu SZ, Açıkgöz A.Milli yenilik sistemleri ve Türkiye için öneriler. Girişimcilik ve İnovasyon Yönetimi Dergisi Journal of Entrepreneurship and Innovation Management ) 1 (1): 69-96, 2012. 8) Kaynak. Ali Riza Erdem Bilimsel etik Yükseköğretim ve Bilim Dergisi 2:1:25-32,2012 9)Gülbaş SY. İnovasyon:Teknopark Modeli . ANKEM Derg 2011;25(Ek 2):139-145 10) Demir M ve Geyik O. Türkiye’de AR-GE ve inovasyon harcamalarının gelişim süreci ve ekonomik etkileri. Journal of Life Economics 2: 171-186, 2014.

Course Contribution to Program Qualifications

Course Contribution to Program Qualifications
NoProgram QualificationContribution Level
12345
1
Defines macro and micromolecules in cell and body fluids at an advanced level.
X
2
Knows how to store and protect the material to be analyzed.
X
3
Knows how to identify molecules found in cells and body fluids.
X
4
Knows the principles of technologies to be used for routine and research purposes.
X
5
Knows how to evaluate the results of the study, interprets and questions.
X
6
Knows how to use field-specific tools and equipment
X
7
Knows how to access and interpret field-specific resources and information
X
8
Shares information with disciplines related to the field
X
9
Combines theoretical and factual knowledge with critical thoughts, conducts independent studies, evaluates the results, compares them with the literature, and gets them accepted by authors and scientific journals.
X
10
Solves a scientific and technical problem, knows where to get help.
X
11
Takes responsibility in joint scientific studies, contributes and works in harmony.
X
12
Participates in meetings related to the field of biochemistry, presents papers, participates in discussions and congresses, publishes studies in reputable journals specific to the field.
X
13
Collects, interprets, applies, announces data related to the field of biochemistry, conducts social and cultural studies, and supervises these studies scientifically and socially.
X
14
Can take part in management activities, evaluate the results obtained to improve quality
X

Assessment Methods

Contribution LevelAbsolute Evaluation
Rate of Midterm Exam to Success 50
Rate of Final Exam to Success 50
Total 100

Numerical Data

Student Success

Ekleme Tarihi: 27/11/2023 - 02:24Son Güncelleme Tarihi: 27/11/2023 - 02:25