Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY | - | Fall Semester | 4+2 | 5 | 10 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Esra ÇAĞAVİ |
| Name of Lecturer(s) | Prof.Dr. Kürşat ÖZDİLLİ, Prof.Dr. Esra ÇAĞAVİ, Assist.Prof. Neşe AYŞİT, Assoc.Prof. Nihal KARAKAŞ, Assist.Prof. İlyas ÖZÇİÇEK, Assist.Prof. Berrak ÇAĞLAYAN, Assist.Prof. Elif Zeynep YILMAZ, Assist.Prof. Salih GENCER, Assist.Prof. Sven Pierre L. VILAIN |
| Assistant(s) | n/a |
| Aim | It is aimed to provide students with advanced knowledge and interpretation skills at the master's level by explaining the relationship between human cell structure and function, defining various disease types especially related to organelle pathologies, explaining the cytoskeleton and cells signaling pathways, and interpreting cellular processes related to DNA and RNA. |
| Course Content | This course contains; Procaryotic and eucaryotic cellular structures and functions,Chromatin, genes and DNA structure andfunction,DNA replication and repair,RNA world, transcription and translation,Organelles and clinical relevance of organelle pathologies,Gene expression regulation and epigenetics,Plasma membrane and endomembrane systems,Cellular protein trafficking, exocytosis, endocytosis and receptor-mediated endocytosis,Cytoskeleton, cellular adhesion and extracellular matrix,Stem cell biology,Cell surface and intracellular receptors and signaling pathways,Cell division, cell senescence and cell death mechanisms,Cancer biology and genetics,Current topic and therapies of cancer. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explain the cell structure and function | 10, 14, 2 | A, E, F |
| Report current scientific literature in medical biology in English at high level | 14, 2 | A |
| Define organelle structure, function and pathologies | 10 | A, E |
| Explain cell cycle, cell death and cancer progression. | 10, 14 | A |
| Define DNA, RNA and associated transcription and translation mechanisms in humans. | 14 | A, E |
| Express cellular signaling mechanisms. | 13, 14 | A, E |
| Teaching Methods: | 10: Discussion Method, 13: Case Study Method, 14: Self Study Method, 2: Project Based Learning Model |
| Assessment Methods: | A: Traditional Written Exam, E: Homework, F: Project Task |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Procaryotic and eucaryotic cellular structures and functions | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 2 should be read before class. |
| 2 | Chromatin, genes and DNA structure andfunction | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 5 should be read before class. |
| 3 | DNA replication and repair | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 8 should be read before class. |
| 4 | RNA world, transcription and translation | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 8 should be read before class. |
| 5 | Organelles and clinical relevance of organelle pathologies | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 4 should be read before class. |
| 6 | Gene expression regulation and epigenetics | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 5 and 8 should be read before class. |
| 7 | Plasma membrane and endomembrane systems | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 3 should be read before class. |
| 8 | Cellular protein trafficking, exocytosis, endocytosis and receptor-mediated endocytosis | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 9 ve 12 should be read before class. |
| 9 | Cytoskeleton, cellular adhesion and extracellular matrix | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 6 and 7 should be read before class. |
| 10 | Stem cell biology | The 6th edition of "Stem Cells" book by Prof. Dr. Alp CAN's Chapter 1 and 2 should be read before class. |
| 11 | Cell surface and intracellular receptors and signaling pathways | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 10 should be read before class. |
| 12 | Cell division, cell senescence and cell death mechanisms | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 11 should be read before class. |
| 13 | Cancer biology and genetics | The 8th edition (Turkish translation) of "Cell: Molecular Approach" book by Prof. Dr. Geoffrey M. Cooper's Chapter 20 should be read before class. |
| 14 | Current topic and therapies of cancer | The 8th edition (Turkish translation) of "Cell: Molecular Approach" book by Prof. Dr. Geoffrey M. Cooper's Chapter 20 should be read before class. |
| Resources |
| 1) 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ 2) 8th edition of "Cell: Molecular approach" Prof. Dr. Geoffrey M. Cooper (Turkish translation) |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | - Defines cell structure, functions and different cell types. | X | |||||
| 2 | Defines the organelles of the cell, their functions and their communication with each other. | X | |||||
| 3 | Explains the basic structure and function of the cell. | X | |||||
| 4 | Explains laboratory equipment and their use. | X | |||||
| 5 | Defines the use of basic laboratory devices. | X | |||||
| 6 | Explains the rules and safety issues to be followed in the laboratory. | X | |||||
| 7 | Can develop a hypothesis for a scientific study based ona scientific question. | X | |||||
| 8 | Can participate in a clinical or non-clinical study and suggest methodological strategy. | X | |||||
| 9 | Can explore advanced biological application and develop laboratory skills to implements and teach them effectively when necessary. | X | |||||
| 10 | Can plan scientific research. | X | |||||
| 11 | Can use scientific databases. | X | |||||
| 12 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | X | |||||
| 13 | Evaluates the basic level of knowledge and skills acquired in the field with a critical approach; identifies learning needs and directs learning. | X | |||||
| 14 | He/she can exchange information and ideas by communicating with others about his/her field and scientific research issues. | X | |||||
| 15 | Follows the literature with advanced foreign language and computer skills. | X | |||||
| 16 | Acts in accordance with the laws, regulations, legislation and professional ethical rules regarding his duties, rights and responsibilities as a Medical Biology Master degree holder. | ||||||
| 17 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 4 | 56 | |||
| Guided Problem Solving | 14 | 3 | 42 | |||
| Resolution of Homework Problems and Submission as a Report | 6 | 10 | 60 | |||
| Term Project | 14 | 4 | 56 | |||
| Presentation of Project / Seminar | 2 | 5 | 10 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 3 | 10 | 30 | |||
| General Exam | 4 | 10 | 40 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 294 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(294/30) | 10 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY | - | Fall Semester | 4+2 | 5 | 10 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Esra ÇAĞAVİ |
| Name of Lecturer(s) | Prof.Dr. Kürşat ÖZDİLLİ, Prof.Dr. Esra ÇAĞAVİ, Assist.Prof. Neşe AYŞİT, Assoc.Prof. Nihal KARAKAŞ, Assist.Prof. İlyas ÖZÇİÇEK, Assist.Prof. Berrak ÇAĞLAYAN, Assist.Prof. Elif Zeynep YILMAZ, Assist.Prof. Salih GENCER, Assist.Prof. Sven Pierre L. VILAIN |
| Assistant(s) | n/a |
| Aim | It is aimed to provide students with advanced knowledge and interpretation skills at the master's level by explaining the relationship between human cell structure and function, defining various disease types especially related to organelle pathologies, explaining the cytoskeleton and cells signaling pathways, and interpreting cellular processes related to DNA and RNA. |
| Course Content | This course contains; Procaryotic and eucaryotic cellular structures and functions,Chromatin, genes and DNA structure andfunction,DNA replication and repair,RNA world, transcription and translation,Organelles and clinical relevance of organelle pathologies,Gene expression regulation and epigenetics,Plasma membrane and endomembrane systems,Cellular protein trafficking, exocytosis, endocytosis and receptor-mediated endocytosis,Cytoskeleton, cellular adhesion and extracellular matrix,Stem cell biology,Cell surface and intracellular receptors and signaling pathways,Cell division, cell senescence and cell death mechanisms,Cancer biology and genetics,Current topic and therapies of cancer. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explain the cell structure and function | 10, 14, 2 | A, E, F |
| Report current scientific literature in medical biology in English at high level | 14, 2 | A |
| Define organelle structure, function and pathologies | 10 | A, E |
| Explain cell cycle, cell death and cancer progression. | 10, 14 | A |
| Define DNA, RNA and associated transcription and translation mechanisms in humans. | 14 | A, E |
| Express cellular signaling mechanisms. | 13, 14 | A, E |
| Teaching Methods: | 10: Discussion Method, 13: Case Study Method, 14: Self Study Method, 2: Project Based Learning Model |
| Assessment Methods: | A: Traditional Written Exam, E: Homework, F: Project Task |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Procaryotic and eucaryotic cellular structures and functions | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 2 should be read before class. |
| 2 | Chromatin, genes and DNA structure andfunction | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 5 should be read before class. |
| 3 | DNA replication and repair | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 8 should be read before class. |
| 4 | RNA world, transcription and translation | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 8 should be read before class. |
| 5 | Organelles and clinical relevance of organelle pathologies | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 4 should be read before class. |
| 6 | Gene expression regulation and epigenetics | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 5 and 8 should be read before class. |
| 7 | Plasma membrane and endomembrane systems | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 3 should be read before class. |
| 8 | Cellular protein trafficking, exocytosis, endocytosis and receptor-mediated endocytosis | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 9 ve 12 should be read before class. |
| 9 | Cytoskeleton, cellular adhesion and extracellular matrix | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 6 and 7 should be read before class. |
| 10 | Stem cell biology | The 6th edition of "Stem Cells" book by Prof. Dr. Alp CAN's Chapter 1 and 2 should be read before class. |
| 11 | Cell surface and intracellular receptors and signaling pathways | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 10 should be read before class. |
| 12 | Cell division, cell senescence and cell death mechanisms | The 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ's Chapter 11 should be read before class. |
| 13 | Cancer biology and genetics | The 8th edition (Turkish translation) of "Cell: Molecular Approach" book by Prof. Dr. Geoffrey M. Cooper's Chapter 20 should be read before class. |
| 14 | Current topic and therapies of cancer | The 8th edition (Turkish translation) of "Cell: Molecular Approach" book by Prof. Dr. Geoffrey M. Cooper's Chapter 20 should be read before class. |
| Resources |
| 1) 6th edition of "Molecular Cell Biology" book by Prof. Dr. Hasan Veysi GÜNEŞ 2) 8th edition of "Cell: Molecular approach" Prof. Dr. Geoffrey M. Cooper (Turkish translation) |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | - Defines cell structure, functions and different cell types. | X | |||||
| 2 | Defines the organelles of the cell, their functions and their communication with each other. | X | |||||
| 3 | Explains the basic structure and function of the cell. | X | |||||
| 4 | Explains laboratory equipment and their use. | X | |||||
| 5 | Defines the use of basic laboratory devices. | X | |||||
| 6 | Explains the rules and safety issues to be followed in the laboratory. | X | |||||
| 7 | Can develop a hypothesis for a scientific study based ona scientific question. | X | |||||
| 8 | Can participate in a clinical or non-clinical study and suggest methodological strategy. | X | |||||
| 9 | Can explore advanced biological application and develop laboratory skills to implements and teach them effectively when necessary. | X | |||||
| 10 | Can plan scientific research. | X | |||||
| 11 | Can use scientific databases. | X | |||||
| 12 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | X | |||||
| 13 | Evaluates the basic level of knowledge and skills acquired in the field with a critical approach; identifies learning needs and directs learning. | X | |||||
| 14 | He/she can exchange information and ideas by communicating with others about his/her field and scientific research issues. | X | |||||
| 15 | Follows the literature with advanced foreign language and computer skills. | X | |||||
| 16 | Acts in accordance with the laws, regulations, legislation and professional ethical rules regarding his duties, rights and responsibilities as a Medical Biology Master degree holder. | ||||||
| 17 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |