Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CELL BIOLOGY and BIOCHEMISTRY | - | Fall Semester | 4+0 | 4 | 9 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Esra Nur YİĞİT |
| Name of Lecturer(s) | Prof.Dr. Gürkan ÖZTÜRK, Prof.Dr. Ahmet Zeki ŞENGİL, Prof.Dr. Türkan YİĞİTBAŞI, Prof.Dr. Süleyman YILDIRIM, Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. Sultan Sibel ERDEM, Assoc.Prof. Bilal Ersen KERMAN, Assist.Prof. Salih GENCER |
| Assistant(s) | |
| Aim | The aim of this course is to examine biochemical reactions occurring within the cell and the molecules used in these reactions, providing information about the structure and functioning of prokaryotic and eukaryotic cells. |
| Course Content | This course contains; Carbohydrates,Lipids,Proteins,Energy Metabolism,Hormones,Vitamins and minerals,Endomembrane System and Organels 1,Endomembrane System and Organels 2,Cytoskeleton and Extracellular environment,Signal transduction mechanisms,Cell Nucleus and DNA,Protein Synthesis,Prokaryotic Cell,Microbial reproduction and metabolism. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Lists the structures and functions of carbohydrates, fats, and proteins. | 10, 16, 9 | E |
| Describes the principles of energy metabolism in eukaryotic cells. | 10, 16, 9 | E |
| Associates the roles of basic biomolecules in cell metabolism with energy production processes. | 10, 16, 9 | E |
| Defines the production, functions, and roles of hormones in signal transduction processes. | 10, 16, 9 | E |
| Evaluates the biochemical functions of vitamins and minerals and their effects on cellular health. | 10, 16, 9 | E |
| Describes the roles of phospholipids, cholesterol, and glycolipids in the cell membrane. | 10, 16, 9 | A |
| Distinguishes membranous structures and organelles within the cell. | 10, 16, 9 | A |
| Establishes cause-and-effect relationships between interactions of organelles within the cell. | 10, 16, 9 | A |
| Associates cytoskeleton elements and motor proteins with their functions. | 10, 16, 9 | A |
| Interprets the effects of changes occurring in the extracellular environment on the intracellular environment. | 10, 16, 9 | A |
| Describes the types of receptors present in the cell membrane and their activation processes. | 10, 16, 9 | A |
| Explains the molecular principles of intercellular and intracellular signal transduction. | 10, 16, 9 | A |
| Analyzes the processes of DNA replication, transcription, and translation. | 10, 16, 9 | A |
| Compares the structure and characteristics of prokaryotic cells with eukaryotic cells. | 10, 16, 9 | A |
| Defines the fundamental characteristics of microbial metabolism. | 10, 16, 9 | A |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Carbohydrates | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 2 | Lipids | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 3 | Proteins | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 4 | Energy Metabolism | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 5 | Hormones | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 74: Introduction to Endocrinology |
| 6 | Vitamins and minerals | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 72: Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals |
| 7 | Endomembrane System and Organels 1 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 10: Membrane Structure |
| 8 | Endomembrane System and Organels 2 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 11: Intracellular Compartments and Protein Sorting |
| 9 | Cytoskeleton and Extracellular environment | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 16: The Cytoskeleton |
| 10 | Signal transduction mechanisms | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 15: Cell Signalling |
| 11 | Cell Nucleus and DNA | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 12 | Protein Synthesis | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 13 | Prokaryotic Cell | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control |
| 14 | Microbial reproduction and metabolism | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control , Part III: Microbial Metabolism |
| Resources |
| Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell Willey J., Sandman K., Wood D., Prescott Microbiology Nelson D., Cox M. Lehninger Principles of Biochemistry Nesrin Emekli, Temel ve Uygulamalı Biyokimya |
| Lecture notes and lecturer's presentations |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | - Defines cell structure, functions and different cell types. | X | |||||
| 2 | Defines the organelles of the cell, their functions and their communication with each other. | X | |||||
| 3 | Explains the basic structure and function of the cell. | X | |||||
| 4 | Explains laboratory equipment and their use. | ||||||
| 5 | Defines the use of basic laboratory devices. | ||||||
| 6 | Explains the rules and safety issues to be followed in the laboratory. | ||||||
| 7 | Can develop a hypothesis for a scientific study based ona scientific question. | ||||||
| 8 | Can participate in a clinical or non-clinical study and suggest methodological strategy. | X | |||||
| 9 | Can explore advanced biological application and develop laboratory skills to implements and teach them effectively when necessary. | ||||||
| 10 | Can plan scientific research. | ||||||
| 11 | Can use scientific databases. | ||||||
| 12 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | ||||||
| 13 | Evaluates the basic level of knowledge and skills acquired in the field with a critical approach; identifies learning needs and directs learning. | ||||||
| 14 | He/she can exchange information and ideas by communicating with others about his/her field and scientific research issues. | ||||||
| 15 | Follows the literature with advanced foreign language and computer skills. | ||||||
| 16 | Acts in accordance with the laws, regulations, legislation and professional ethical rules regarding his duties, rights and responsibilities as a Medical Biology Master degree holder. | ||||||
| 17 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 4 | 56 | |||
| Guided Problem Solving | 14 | 8 | 112 | |||
| Resolution of Homework Problems and Submission as a Report | 2 | 10 | 20 | |||
| Term Project | 1 | 5 | 5 | |||
| Presentation of Project / Seminar | 1 | 5 | 5 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 30 | 30 | |||
| General Exam | 1 | 36 | 36 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 264 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(264/30) | 9 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CELL BIOLOGY and BIOCHEMISTRY | - | Fall Semester | 4+0 | 4 | 9 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Esra Nur YİĞİT |
| Name of Lecturer(s) | Prof.Dr. Gürkan ÖZTÜRK, Prof.Dr. Ahmet Zeki ŞENGİL, Prof.Dr. Türkan YİĞİTBAŞI, Prof.Dr. Süleyman YILDIRIM, Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. Sultan Sibel ERDEM, Assoc.Prof. Bilal Ersen KERMAN, Assist.Prof. Salih GENCER |
| Assistant(s) | |
| Aim | The aim of this course is to examine biochemical reactions occurring within the cell and the molecules used in these reactions, providing information about the structure and functioning of prokaryotic and eukaryotic cells. |
| Course Content | This course contains; Carbohydrates,Lipids,Proteins,Energy Metabolism,Hormones,Vitamins and minerals,Endomembrane System and Organels 1,Endomembrane System and Organels 2,Cytoskeleton and Extracellular environment,Signal transduction mechanisms,Cell Nucleus and DNA,Protein Synthesis,Prokaryotic Cell,Microbial reproduction and metabolism. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Lists the structures and functions of carbohydrates, fats, and proteins. | 10, 16, 9 | E |
| Describes the principles of energy metabolism in eukaryotic cells. | 10, 16, 9 | E |
| Associates the roles of basic biomolecules in cell metabolism with energy production processes. | 10, 16, 9 | E |
| Defines the production, functions, and roles of hormones in signal transduction processes. | 10, 16, 9 | E |
| Evaluates the biochemical functions of vitamins and minerals and their effects on cellular health. | 10, 16, 9 | E |
| Describes the roles of phospholipids, cholesterol, and glycolipids in the cell membrane. | 10, 16, 9 | A |
| Distinguishes membranous structures and organelles within the cell. | 10, 16, 9 | A |
| Establishes cause-and-effect relationships between interactions of organelles within the cell. | 10, 16, 9 | A |
| Associates cytoskeleton elements and motor proteins with their functions. | 10, 16, 9 | A |
| Interprets the effects of changes occurring in the extracellular environment on the intracellular environment. | 10, 16, 9 | A |
| Describes the types of receptors present in the cell membrane and their activation processes. | 10, 16, 9 | A |
| Explains the molecular principles of intercellular and intracellular signal transduction. | 10, 16, 9 | A |
| Analyzes the processes of DNA replication, transcription, and translation. | 10, 16, 9 | A |
| Compares the structure and characteristics of prokaryotic cells with eukaryotic cells. | 10, 16, 9 | A |
| Defines the fundamental characteristics of microbial metabolism. | 10, 16, 9 | A |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Carbohydrates | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 2 | Lipids | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 3 | Proteins | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 4 | Energy Metabolism | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 5 | Hormones | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 74: Introduction to Endocrinology |
| 6 | Vitamins and minerals | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 72: Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals |
| 7 | Endomembrane System and Organels 1 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 10: Membrane Structure |
| 8 | Endomembrane System and Organels 2 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 11: Intracellular Compartments and Protein Sorting |
| 9 | Cytoskeleton and Extracellular environment | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 16: The Cytoskeleton |
| 10 | Signal transduction mechanisms | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 15: Cell Signalling |
| 11 | Cell Nucleus and DNA | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 12 | Protein Synthesis | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 13 | Prokaryotic Cell | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control |
| 14 | Microbial reproduction and metabolism | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control , Part III: Microbial Metabolism |
| Resources |
| Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell Willey J., Sandman K., Wood D., Prescott Microbiology Nelson D., Cox M. Lehninger Principles of Biochemistry Nesrin Emekli, Temel ve Uygulamalı Biyokimya |
| Lecture notes and lecturer's presentations |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | - Defines cell structure, functions and different cell types. | X | |||||
| 2 | Defines the organelles of the cell, their functions and their communication with each other. | X | |||||
| 3 | Explains the basic structure and function of the cell. | X | |||||
| 4 | Explains laboratory equipment and their use. | ||||||
| 5 | Defines the use of basic laboratory devices. | ||||||
| 6 | Explains the rules and safety issues to be followed in the laboratory. | ||||||
| 7 | Can develop a hypothesis for a scientific study based ona scientific question. | ||||||
| 8 | Can participate in a clinical or non-clinical study and suggest methodological strategy. | X | |||||
| 9 | Can explore advanced biological application and develop laboratory skills to implements and teach them effectively when necessary. | ||||||
| 10 | Can plan scientific research. | ||||||
| 11 | Can use scientific databases. | ||||||
| 12 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | ||||||
| 13 | Evaluates the basic level of knowledge and skills acquired in the field with a critical approach; identifies learning needs and directs learning. | ||||||
| 14 | He/she can exchange information and ideas by communicating with others about his/her field and scientific research issues. | ||||||
| 15 | Follows the literature with advanced foreign language and computer skills. | ||||||
| 16 | Acts in accordance with the laws, regulations, legislation and professional ethical rules regarding his duties, rights and responsibilities as a Medical Biology Master degree holder. | ||||||
| 17 | Carries out a given task independently by using the basic knowledge he/she has in his/her field. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |