Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CLINICAL BIOCHEMISTRY | - | Fall Semester | 2+0 | 2 | 6 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assoc.Prof. Ozan Emre EYUPOĞLU |
| Name of Lecturer(s) | Assist.Prof. Adnan HAŞİMİ |
| Assistant(s) | |
| Aim | To describe and teach all the chemical reactions in the cell at the molecular level, to understand the changes that occur in these reactions in pathological situations, to identify the biochemical parameters used in the diagnosis, treatment and prevention of diseases. |
| Course Content | This course contains; 1-General concepts in biochemistry,2- Energy metabolisms,3- Energy metabolisms,4. How does the clinical biochemistry laboratory work?,5-Interpretation of carbohydrate metabolism and related tests,6-Liver function tests,7-Kidney function tests,8-Atherosclerosis and lipid metabolism,9-Anemiler, laboratory analysis and interpretation,10-Cardiac markers and clinical approach,11. Hormones and approach to clinical diagnosis,12-Vitamins,13-Works and ultraeser elements,14- Clinical interpretation of biochemical tests with pharmacist perspective. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course the student; | ||
| 1-It can compare the structure of macro and micro molecules important for the organism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explain carbohydrates, lipids, proteins structures, digestion and absorption. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Compares and classifies micro and micro minerals. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2-Question the functions of macromolecules in organism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Inquires the importance of micro and micro minerals and vitamins in metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3.Compares the functions of hormone, enzyme, carbohydrate, protein and fat in metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-It can question the laboratory results of normal and disease state of macro and micro molecules. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4-Recognise the clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Explain workflow in clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3. Structurally question hormones and enzymes. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4. Summarize the structure and function of vitamins and minerals. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1. Compare the pathways used for energy from macromolecules and the metabolism of macromolecules . | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1. The tests used to evaluate carbohydrate metabolism (AKG, OGTT, HbA1C) are categorized. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2. Interferes with laboratory results of atherosclerosis and blood lipids | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3. In the laboratory, the liver questions how kidney functions and anemia are interpreted. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Discuss the differences and clinical uses of cardiac markers. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.5. How hormones are affected in diseases | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2. Comments the test result relationship of clinical biochemistry with the pharmacist perspective. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3. Comments laboratory quality concepts and laboratory errors. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1-General concepts in biochemistry | 1, 2, 3, 4 |
| 2 | 2- Energy metabolisms | 1, 2, 3, 4 |
| 3 | 3- Energy metabolisms | 1, 2, 3, 4 |
| 4 | 4. How does the clinical biochemistry laboratory work? | 1, 2, 3, 4 |
| 5 | 5-Interpretation of carbohydrate metabolism and related tests | 1, 2, 3, 4 |
| 6 | 6-Liver function tests | 1, 2, 3, 4 |
| 7 | 7-Kidney function tests | 1, 2, 3, 4 |
| 8 | 8-Atherosclerosis and lipid metabolism | 1, 2, 3, 4 |
| 9 | 9-Anemiler, laboratory analysis and interpretation | 1, 2, 3, 4 |
| 10 | 10-Cardiac markers and clinical approach | 1, 2, 3, 4 |
| 11 | 11. Hormones and approach to clinical diagnosis | 1, 2, 3, 4 |
| 12 | 12-Vitamins | 1, 2, 3, 4 |
| 13 | 13-Works and ultraeser elements | 1, 2, 3, 4 |
| 14 | 14- Clinical interpretation of biochemical tests with pharmacist perspective | 1, 2, 3, 4 |
| Resources |
| 1-Biyokimya Laboratuvarı,Türkan Yiğitbaşı,Nesrin Emekli,Medipol Üniversitesi Yayınları 004,İstanbul,2013. 2-Harper’s Illustrated Bio chemistry, R.K. Murray, D.A. Bender, K.M. Botham, V.W. Rodwell,P.A. Weil, McGrawHill, 2009. 3- Lippincot’s Illustrated Reviews, Biochemistry, P.C. Champ, R.A. Harvey, D.R. Ferrier, LWW, 2008 4.Biyokimya (2. Baskı) Figen Gürdöl, Evin Ademoğlu, Nobel Tıp Kitabevleri, İstanbul, 2010 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PY-1. Knows about accessing the scientific information in the field of clinical pharmacy, monitoring, evaluating, and implementing the current literature | X | |||||
| 2 | PY-2. Has the advanced knowledge of creating patient profiles, patient education, and medication counseling. | X | |||||
| 3 | PY-3. Cooperates with persons in relevant disciplines at the stages of collecting, interpreting, implementing, and announcing results of data related to the clinical pharmacy field | ||||||
| 4 | PY-4. Uses the knowledge and equipment related to administering medicine to patients and the use of the drug. Gives pharmaceutical care service by providing rational and safe drug use with the duty of observance and supervision. | ||||||
| 5 | PY-5. Acquires administrative and technical stand-by equipment in the areas where the clinical pharmacy is responsible for and achieves hospital pharmacy practices properly. | ||||||
| 6 | PY-6. Produces solutions to the problems in the field of clinical pharmacy in the direction of scientific data/ scientific evidence. | ||||||
| 7 | PY-7. Plans, manages, watches the process, and evaluates activities that oriented improvements of employees as part of a project. | X | |||||
| 8 | PY-8. Carries out a study independently by using advanced level knowledge about the field of clinical pharmacy and takes responsibility as a team member in cooperation with other occupational groups working in this field. | X | |||||
| 9 | PY-9. Demonstrates embarking on lifelong learning, open for improvement, and continue this behavior. | ||||||
| 10 | PY-10. Follows and evaluates national and international developments in the field of clinical pharmacy. | ||||||
| 11 | PY-11. Safely documents and keeps track of professional activities and practices. | ||||||
| 12 | PY-12. Provides information to the patience, healthcare personnel, and society on every drug-related issue. | ||||||
| 13 | PY-13. Informs relevant persons and institutions in the fields of quality assurance of pharmaceutical products | ||||||
| 14 | PY-14. Behaves according to the legislation and professional ethics related to duty, right, and responsibilities as an individual. | ||||||
| 15 | PY-15. Has sufficient consciousness in the field of individual and public health, environmental protection, and job security and applies it. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 14 | 4 | 56 | |||
| Resolution of Homework Problems and Submission as a Report | 10 | 2 | 20 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 10 | 2 | 20 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 14 | 2 | 28 | |||
| General Exam | 14 | 2 | 28 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 180 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(180/30) | 6 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CLINICAL BIOCHEMISTRY | - | Fall Semester | 2+0 | 2 | 6 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assoc.Prof. Ozan Emre EYUPOĞLU |
| Name of Lecturer(s) | Assist.Prof. Adnan HAŞİMİ |
| Assistant(s) | |
| Aim | To describe and teach all the chemical reactions in the cell at the molecular level, to understand the changes that occur in these reactions in pathological situations, to identify the biochemical parameters used in the diagnosis, treatment and prevention of diseases. |
| Course Content | This course contains; 1-General concepts in biochemistry,2- Energy metabolisms,3- Energy metabolisms,4. How does the clinical biochemistry laboratory work?,5-Interpretation of carbohydrate metabolism and related tests,6-Liver function tests,7-Kidney function tests,8-Atherosclerosis and lipid metabolism,9-Anemiler, laboratory analysis and interpretation,10-Cardiac markers and clinical approach,11. Hormones and approach to clinical diagnosis,12-Vitamins,13-Works and ultraeser elements,14- Clinical interpretation of biochemical tests with pharmacist perspective. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course the student; | ||
| 1-It can compare the structure of macro and micro molecules important for the organism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explain carbohydrates, lipids, proteins structures, digestion and absorption. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Compares and classifies micro and micro minerals. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2-Question the functions of macromolecules in organism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Inquires the importance of micro and micro minerals and vitamins in metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3.Compares the functions of hormone, enzyme, carbohydrate, protein and fat in metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-It can question the laboratory results of normal and disease state of macro and micro molecules. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4-Recognise the clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Explain workflow in clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3. Structurally question hormones and enzymes. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4. Summarize the structure and function of vitamins and minerals. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1. Compare the pathways used for energy from macromolecules and the metabolism of macromolecules . | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1. The tests used to evaluate carbohydrate metabolism (AKG, OGTT, HbA1C) are categorized. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2. Interferes with laboratory results of atherosclerosis and blood lipids | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3. In the laboratory, the liver questions how kidney functions and anemia are interpreted. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Discuss the differences and clinical uses of cardiac markers. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.5. How hormones are affected in diseases | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2. Comments the test result relationship of clinical biochemistry with the pharmacist perspective. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3. Comments laboratory quality concepts and laboratory errors. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | 1-General concepts in biochemistry | 1, 2, 3, 4 |
| 2 | 2- Energy metabolisms | 1, 2, 3, 4 |
| 3 | 3- Energy metabolisms | 1, 2, 3, 4 |
| 4 | 4. How does the clinical biochemistry laboratory work? | 1, 2, 3, 4 |
| 5 | 5-Interpretation of carbohydrate metabolism and related tests | 1, 2, 3, 4 |
| 6 | 6-Liver function tests | 1, 2, 3, 4 |
| 7 | 7-Kidney function tests | 1, 2, 3, 4 |
| 8 | 8-Atherosclerosis and lipid metabolism | 1, 2, 3, 4 |
| 9 | 9-Anemiler, laboratory analysis and interpretation | 1, 2, 3, 4 |
| 10 | 10-Cardiac markers and clinical approach | 1, 2, 3, 4 |
| 11 | 11. Hormones and approach to clinical diagnosis | 1, 2, 3, 4 |
| 12 | 12-Vitamins | 1, 2, 3, 4 |
| 13 | 13-Works and ultraeser elements | 1, 2, 3, 4 |
| 14 | 14- Clinical interpretation of biochemical tests with pharmacist perspective | 1, 2, 3, 4 |
| Resources |
| 1-Biyokimya Laboratuvarı,Türkan Yiğitbaşı,Nesrin Emekli,Medipol Üniversitesi Yayınları 004,İstanbul,2013. 2-Harper’s Illustrated Bio chemistry, R.K. Murray, D.A. Bender, K.M. Botham, V.W. Rodwell,P.A. Weil, McGrawHill, 2009. 3- Lippincot’s Illustrated Reviews, Biochemistry, P.C. Champ, R.A. Harvey, D.R. Ferrier, LWW, 2008 4.Biyokimya (2. Baskı) Figen Gürdöl, Evin Ademoğlu, Nobel Tıp Kitabevleri, İstanbul, 2010 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PY-1. Knows about accessing the scientific information in the field of clinical pharmacy, monitoring, evaluating, and implementing the current literature | X | |||||
| 2 | PY-2. Has the advanced knowledge of creating patient profiles, patient education, and medication counseling. | X | |||||
| 3 | PY-3. Cooperates with persons in relevant disciplines at the stages of collecting, interpreting, implementing, and announcing results of data related to the clinical pharmacy field | ||||||
| 4 | PY-4. Uses the knowledge and equipment related to administering medicine to patients and the use of the drug. Gives pharmaceutical care service by providing rational and safe drug use with the duty of observance and supervision. | ||||||
| 5 | PY-5. Acquires administrative and technical stand-by equipment in the areas where the clinical pharmacy is responsible for and achieves hospital pharmacy practices properly. | ||||||
| 6 | PY-6. Produces solutions to the problems in the field of clinical pharmacy in the direction of scientific data/ scientific evidence. | ||||||
| 7 | PY-7. Plans, manages, watches the process, and evaluates activities that oriented improvements of employees as part of a project. | X | |||||
| 8 | PY-8. Carries out a study independently by using advanced level knowledge about the field of clinical pharmacy and takes responsibility as a team member in cooperation with other occupational groups working in this field. | X | |||||
| 9 | PY-9. Demonstrates embarking on lifelong learning, open for improvement, and continue this behavior. | ||||||
| 10 | PY-10. Follows and evaluates national and international developments in the field of clinical pharmacy. | ||||||
| 11 | PY-11. Safely documents and keeps track of professional activities and practices. | ||||||
| 12 | PY-12. Provides information to the patience, healthcare personnel, and society on every drug-related issue. | ||||||
| 13 | PY-13. Informs relevant persons and institutions in the fields of quality assurance of pharmaceutical products | ||||||
| 14 | PY-14. Behaves according to the legislation and professional ethics related to duty, right, and responsibilities as an individual. | ||||||
| 15 | PY-15. Has sufficient consciousness in the field of individual and public health, environmental protection, and job security and applies it. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |