Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CELL BIOLOGY and BIOCHEMISTRY | - | Spring Semester | 4+0 | 4 | 9 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Esra Nur YİĞİT |
| Name of Lecturer(s) | Prof.Dr. Gürkan ÖZTÜRK, Prof.Dr. Türkan YİĞİTBAŞI, Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. Sultan Sibel ERDEM, Prof.Dr. Süleyman YILDIRIM, Assist.Prof. Salih GENCER, Assist.Prof. Neşe AYŞİT, Assist.Prof. Berrak ÇAĞLAYAN |
| Assistant(s) | |
| Aim | The aim of this course is to examine biochemical reactions occurring within the cell and the molecules used in these reactions, providing information about the structure and functioning of prokaryotic and eukaryotic cells. |
| Course Content | This course contains; Carbohydrates,Lipids,Proteins,Energy Metabolism,Hormones,Vitamins and minerals,Endomembrane System and Organels 1,Endomembrane System and Organels 2,Cytoskeleton and Extracellular environment,Signal transduction mechanisms,Cell Nucleus and DNA,Protein Synthesis,Prokaryotic Cell,Microbial reproduction and metabolism. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Lists the structures and functions of carbohydrates, fats, and proteins. | 10, 16, 9 | E |
| Describes the principles of energy metabolism in eukaryotic cells. | 10, 16, 9 | E |
| Associates the roles of basic biomolecules in cell metabolism with energy production processes. | 10, 16, 9 | E |
| Defines the production, functions, and roles of hormones in signal transduction processes. | 10, 16, 9 | E |
| Evaluates the biochemical functions of vitamins and minerals and their effects on cellular health. | 10, 16, 9 | E |
| Describes the roles of phospholipids, cholesterol, and glycolipids in the cell membrane. | 10, 16, 9 | A |
| Distinguishes membranous structures and organelles within the cell. | 10, 16, 9 | A |
| Establishes cause-and-effect relationships between interactions of organelles within the cell. | 10, 16, 9 | A |
| Associates cytoskeleton elements and motor proteins with their functions. | 10, 16, 9 | A |
| Interprets the effects of changes occurring in the extracellular environment on the intracellular environment. | 10, 16, 9 | A |
| Describes the types of receptors present in the cell membrane and their activation processes. | 10, 16, 9 | A |
| Explains the molecular principles of intercellular and intracellular signal transduction. | 10, 16, 9 | A |
| Analyzes the processes of DNA replication, transcription, and translation. | 10, 16, 9 | A |
| Compares the structure and characteristics of prokaryotic cells with eukaryotic cells. | 10, 16, 9 | A |
| Defines the fundamental characteristics of microbial metabolism. | 10, 16, 9 | A |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Carbohydrates | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 2 | Lipids | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 3 | Proteins | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 4 | Energy Metabolism | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 5 | Hormones | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 74: Introduction to Endocrinology |
| 6 | Vitamins and minerals | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 72: Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals |
| 7 | Endomembrane System and Organels 1 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 10: Membrane Structure |
| 8 | Endomembrane System and Organels 2 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 11: Intracellular Compartments and Protein Sorting |
| 9 | Cytoskeleton and Extracellular environment | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 16: The Cytoskeleton |
| 10 | Signal transduction mechanisms | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 15: Cell Signalling |
| 11 | Cell Nucleus and DNA | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 12 | Protein Synthesis | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 13 | Prokaryotic Cell | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control |
| 14 | Microbial reproduction and metabolism | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control , Part III: Microbial Metabolism |
| Resources |
| Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell Willey J., Sandman K., Wood D., Prescott Microbiology Nelson D., Cox M. Lehninger Principles of Biochemistry Nesrin Emekli, Temel ve Uygulamalı Biyokimya |
| Lecture notes and lecturer's presentations |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows the biochemical macromolecular metabolism. Applies and advances the knowlegde. | X | |||||
| 2 | Knows the principles of routine and research oriented biochemical technologies. | X | |||||
| 3 | Practical Laboratory Applications (Sampling conditions of various body fluids and tissue samples in health and disease states, reasons of analytical errors, storage conditions of samples,working principles of technologies used in routine and research based studies, determinig reference values.) | ||||||
| 4 | Knows basic biostatistics methods, applies to experimental study results and evaluates. | ||||||
| 5 | Knows how to use specific instruments in biochemistry | ||||||
| 6 | Can access printeed and electronic literature and able to follow the advancements in biochemistry and related field. | ||||||
| 7 | Can integrate and interpret the knowledge gained in biochemistry with knowledge obtained in other fields and can generate new information. | X | |||||
| 8 | Independantly applies his/her theoretical knowledge, critical thinking skills to the area of study, evaluates the results and writes a report. | ||||||
| 9 | Defines a technical or scientific problem either with the helpof an advisor or independently, can come up with proposals and solve when needed. | ||||||
| 10 | Take on responsibility in collborative studies, contributes and work in harmony. | ||||||
| 11 | Follows national and international literature in Biochemistry, presents the work in seminars or publishes in journals. | ||||||
| 12 | Can evaluate and teach biochemical data collection, interpretation, application and decleration recpecting cultural, scientific, social and ethical values. | ||||||
| 13 | Take responsibility in managing, evaluate the results according to the context of quality processes. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 4 | 56 | |||
| Guided Problem Solving | 14 | 8 | 112 | |||
| Resolution of Homework Problems and Submission as a Report | 2 | 10 | 20 | |||
| Term Project | 1 | 5 | 5 | |||
| Presentation of Project / Seminar | 1 | 5 | 5 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 30 | 30 | |||
| General Exam | 1 | 36 | 36 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 264 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(264/30) | 9 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| CELL BIOLOGY and BIOCHEMISTRY | - | Spring Semester | 4+0 | 4 | 9 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Esra Nur YİĞİT |
| Name of Lecturer(s) | Prof.Dr. Gürkan ÖZTÜRK, Prof.Dr. Türkan YİĞİTBAŞI, Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. Sultan Sibel ERDEM, Prof.Dr. Süleyman YILDIRIM, Assist.Prof. Salih GENCER, Assist.Prof. Neşe AYŞİT, Assist.Prof. Berrak ÇAĞLAYAN |
| Assistant(s) | |
| Aim | The aim of this course is to examine biochemical reactions occurring within the cell and the molecules used in these reactions, providing information about the structure and functioning of prokaryotic and eukaryotic cells. |
| Course Content | This course contains; Carbohydrates,Lipids,Proteins,Energy Metabolism,Hormones,Vitamins and minerals,Endomembrane System and Organels 1,Endomembrane System and Organels 2,Cytoskeleton and Extracellular environment,Signal transduction mechanisms,Cell Nucleus and DNA,Protein Synthesis,Prokaryotic Cell,Microbial reproduction and metabolism. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Lists the structures and functions of carbohydrates, fats, and proteins. | 10, 16, 9 | E |
| Describes the principles of energy metabolism in eukaryotic cells. | 10, 16, 9 | E |
| Associates the roles of basic biomolecules in cell metabolism with energy production processes. | 10, 16, 9 | E |
| Defines the production, functions, and roles of hormones in signal transduction processes. | 10, 16, 9 | E |
| Evaluates the biochemical functions of vitamins and minerals and their effects on cellular health. | 10, 16, 9 | E |
| Describes the roles of phospholipids, cholesterol, and glycolipids in the cell membrane. | 10, 16, 9 | A |
| Distinguishes membranous structures and organelles within the cell. | 10, 16, 9 | A |
| Establishes cause-and-effect relationships between interactions of organelles within the cell. | 10, 16, 9 | A |
| Associates cytoskeleton elements and motor proteins with their functions. | 10, 16, 9 | A |
| Interprets the effects of changes occurring in the extracellular environment on the intracellular environment. | 10, 16, 9 | A |
| Describes the types of receptors present in the cell membrane and their activation processes. | 10, 16, 9 | A |
| Explains the molecular principles of intercellular and intracellular signal transduction. | 10, 16, 9 | A |
| Analyzes the processes of DNA replication, transcription, and translation. | 10, 16, 9 | A |
| Compares the structure and characteristics of prokaryotic cells with eukaryotic cells. | 10, 16, 9 | A |
| Defines the fundamental characteristics of microbial metabolism. | 10, 16, 9 | A |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Carbohydrates | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 2 | Lipids | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 3 | Proteins | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 4 | Energy Metabolism | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 2: Cell Chemistry and Bioenergetics |
| 5 | Hormones | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 74: Introduction to Endocrinology |
| 6 | Vitamins and minerals | John E. Hall - Guyton and Hall Textbook of Medical Physiology, Chapter 72: Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals |
| 7 | Endomembrane System and Organels 1 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 10: Membrane Structure |
| 8 | Endomembrane System and Organels 2 | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 11: Intracellular Compartments and Protein Sorting |
| 9 | Cytoskeleton and Extracellular environment | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 16: The Cytoskeleton |
| 10 | Signal transduction mechanisms | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 15: Cell Signalling |
| 11 | Cell Nucleus and DNA | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 12 | Protein Synthesis | Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell, Chapter 6: How Cells Read the Genome:From DNA to Protein |
| 13 | Prokaryotic Cell | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control |
| 14 | Microbial reproduction and metabolism | Willey J., Sandman K., Wood D., Prescott Microbiology, Part II: Microbial Nutrition Growth and Control , Part III: Microbial Metabolism |
| Resources |
| Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P., Molecular Biology of the Cell Willey J., Sandman K., Wood D., Prescott Microbiology Nelson D., Cox M. Lehninger Principles of Biochemistry Nesrin Emekli, Temel ve Uygulamalı Biyokimya |
| Lecture notes and lecturer's presentations |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows the biochemical macromolecular metabolism. Applies and advances the knowlegde. | X | |||||
| 2 | Knows the principles of routine and research oriented biochemical technologies. | X | |||||
| 3 | Practical Laboratory Applications (Sampling conditions of various body fluids and tissue samples in health and disease states, reasons of analytical errors, storage conditions of samples,working principles of technologies used in routine and research based studies, determinig reference values.) | ||||||
| 4 | Knows basic biostatistics methods, applies to experimental study results and evaluates. | ||||||
| 5 | Knows how to use specific instruments in biochemistry | ||||||
| 6 | Can access printeed and electronic literature and able to follow the advancements in biochemistry and related field. | ||||||
| 7 | Can integrate and interpret the knowledge gained in biochemistry with knowledge obtained in other fields and can generate new information. | X | |||||
| 8 | Independantly applies his/her theoretical knowledge, critical thinking skills to the area of study, evaluates the results and writes a report. | ||||||
| 9 | Defines a technical or scientific problem either with the helpof an advisor or independently, can come up with proposals and solve when needed. | ||||||
| 10 | Take on responsibility in collborative studies, contributes and work in harmony. | ||||||
| 11 | Follows national and international literature in Biochemistry, presents the work in seminars or publishes in journals. | ||||||
| 12 | Can evaluate and teach biochemical data collection, interpretation, application and decleration recpecting cultural, scientific, social and ethical values. | ||||||
| 13 | Take responsibility in managing, evaluate the results according to the context of quality processes. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |