Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| APPLIED BIOCHEMISTRY | - | Fall Semester | 1+6 | 4 | 10 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Çağrı ÇAKICI |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Derya CANSIZ, Assist.Prof. Çağrı ÇAKICI, Assist.Prof. Gözde ÜLFER |
| Assistant(s) | Prof.Dr.Nesrin Emekli, Assoc. Prof. Dr.Türkan Yiğitbaşı, Ass. Prof .Dr.Sibel Erdem |
| Aim | Teaching theoretical and practical work in the laboratory rules, concepts and techniques in an advanced level |
| Course Content | This course contains; Laboratory accidents and precautions ,Laboratrory materials and cleaning methods,Distilled, deionized water, weighing,cleaning in laboratory ,Density and concentration of solutions ,Molarity, normality and osmolarity ,Acids, bases, and pH concepts, buffer systems,Laboratory tests using light intensity ,Laboratory tests for low concentrations of substances,Protein electrophoresis,Biochemical tests per-patient,Sample collection and storage from body fluids,Anticoagulants in laboratory tests ,Blood proteins, separation and measurement methods,Blood lipids separation and measurement methods. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1-Analyzes the working conditions of the clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explains the rules of working in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Compares individual safety rules. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3.Defines the points to be considered when working with chemicals. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4.Compares carcinogenic substances and special extra hazardous substances. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.5.Explains ways to protect against fire and other harmful substances. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2- Can compare the materials used in the clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Defines the cleaning materials used in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3.Laboratuarda kullanılan metal malzemeleri tanımlar. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Can compare the concepts of solution and concentration. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1.% explains how the solutions are prepared. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2.Explains how to prepare Molar and Normal solutions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.6.Discuss preanalytical, analytical and postanalytical errors. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.Explains phylebotomy and sample collection. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Applies phylebotomy and explains the relevant vascular anatomy. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2.Discuss infection control during phylebotomy. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3.Defines venous collection materials. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4.Defines what procedures can be performed on blood samples. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.5.Defines hemolysis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.6.Defines the storage and transportation conditions of blood. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5-Can compare the instruments used in the biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2.Can use precision scales and desiccators. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.1.Can perform measurements of carbohydrates in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.2.Makes measurements of lipids in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.3.Proteinlerin laboratuvarda ölçümlerini ve elektroforezini tanımlar. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.4.Discuss the measurement principles of enzymes. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7-You can access printed and electronic information sources and learn about biochemistry and related fields. follows the developments. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1 defines the glass materials used in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.4. Defines filter papers and pH paper used in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3. Define isotonic and osmolar solutions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Defines buffer solutions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.5. Discusses pH measurement and its importance. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1. Can use distilled water device. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3. Applies spectrophotometric, colorimetric and photometric measurements. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.4. Explains the principle of the autoanalyzer used in clinical chemistry. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6. Can compare measurements of macromolecules in clinical biochemistry. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Laboratory accidents and precautions | 1, 2, 3, 4, 5 |
| 2 | Laboratrory materials and cleaning methods | 1, 2, 3, 4, 5 |
| 3 | Distilled, deionized water, weighing,cleaning in laboratory | 1, 2, 3, 4, 5 |
| 4 | Density and concentration of solutions | 1, 2, 3, 4, 5 |
| 5 | Molarity, normality and osmolarity | 1, 2, 3, 4, 5 |
| 6 | Acids, bases, and pH concepts, buffer systems | 1, 2, 3, 4, 5 |
| 7 | Laboratory tests using light intensity | 1, 2, 3, 4, 5 |
| 8 | Laboratory tests for low concentrations of substances | 1, 2, 3, 4, 5 |
| 9 | Protein electrophoresis | 1, 2, 3, 4, 5 |
| 10 | Biochemical tests per-patient | 1, 2, 3, 4, 5 |
| 11 | Sample collection and storage from body fluids | 1, 2, 3, 4, 5 |
| 12 | Anticoagulants in laboratory tests | 1, 2, 3, 4, 5 |
| 13 | Blood proteins, separation and measurement methods | 1, 2, 3, 4, 5 |
| 14 | Blood lipids separation and measurement methods | 1, 2, 3, 4, 5 |
| Resources |
| 1) Temel ve Uygulamalı Biyokimya Prof. Dr. Nesrin Emekli Academi Kitapevi Yayınları , 2) Öğrenciler için Biyokimya Laboratuarı Doç. Dr. Türkan Yiğitbaşı ve Prof.Dr.Nesrin Emekli , 3) Klinik Biyokimya Prof. Dr. Nesrin Emekli ve Doç. Dr. Türkan Yiğitbaşı Medipol Üniversitesi Yayınları, 4) Harper Biochemistry (Son Baskı), 5) Kolay Biyokimya (Batırel ve ark.) |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows the biochemical macromolecular metabolism. Applies and advances the knowlegde. | X | |||||
| 2 | Knows the principles of routine and research oriented biochemical technologies. | X | |||||
| 3 | Practical Laboratory Applications (Sampling conditions of various body fluids and tissue samples in health and disease states, reasons of analytical errors, storage conditions of samples,working principles of technologies used in routine and research based studies, determinig reference values.) | X | |||||
| 4 | Knows basic biostatistics methods, applies to experimental study results and evaluates. | ||||||
| 5 | Knows how to use specific instruments in biochemistry | X | |||||
| 6 | Can access printeed and electronic literature and able to follow the advancements in biochemistry and related field. | ||||||
| 7 | Can integrate and interpret the knowledge gained in biochemistry with knowledge obtained in other fields and can generate new information. | X | |||||
| 8 | Independantly applies his/her theoretical knowledge, critical thinking skills to the area of study, evaluates the results and writes a report. | X | |||||
| 9 | Defines a technical or scientific problem either with the helpof an advisor or independently, can come up with proposals and solve when needed. | X | |||||
| 10 | Take on responsibility in collborative studies, contributes and work in harmony. | X | |||||
| 11 | Follows national and international literature in Biochemistry, presents the work in seminars or publishes in journals. | X | |||||
| 12 | Can evaluate and teach biochemical data collection, interpretation, application and decleration recpecting cultural, scientific, social and ethical values. | X | |||||
| 13 | Take responsibility in managing, evaluate the results according to the context of quality processes. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 4 | 56 | |||
| Guided Problem Solving | 14 | 4 | 56 | |||
| Resolution of Homework Problems and Submission as a Report | 5 | 10 | 50 | |||
| Term Project | 5 | 10 | 50 | |||
| Presentation of Project / Seminar | 2 | 10 | 20 | |||
| Quiz | 1 | 5 | 5 | |||
| Midterm Exam | 1 | 25 | 25 | |||
| General Exam | 1 | 35 | 35 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 297 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(297/30) | 10 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| APPLIED BIOCHEMISTRY | - | Fall Semester | 1+6 | 4 | 10 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Assist.Prof. Çağrı ÇAKICI |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Derya CANSIZ, Assist.Prof. Çağrı ÇAKICI, Assist.Prof. Gözde ÜLFER |
| Assistant(s) | Prof.Dr.Nesrin Emekli, Assoc. Prof. Dr.Türkan Yiğitbaşı, Ass. Prof .Dr.Sibel Erdem |
| Aim | Teaching theoretical and practical work in the laboratory rules, concepts and techniques in an advanced level |
| Course Content | This course contains; Laboratory accidents and precautions ,Laboratrory materials and cleaning methods,Distilled, deionized water, weighing,cleaning in laboratory ,Density and concentration of solutions ,Molarity, normality and osmolarity ,Acids, bases, and pH concepts, buffer systems,Laboratory tests using light intensity ,Laboratory tests for low concentrations of substances,Protein electrophoresis,Biochemical tests per-patient,Sample collection and storage from body fluids,Anticoagulants in laboratory tests ,Blood proteins, separation and measurement methods,Blood lipids separation and measurement methods. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1-Analyzes the working conditions of the clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1.Explains the rules of working in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2.Compares individual safety rules. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3.Defines the points to be considered when working with chemicals. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4.Compares carcinogenic substances and special extra hazardous substances. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.5.Explains ways to protect against fire and other harmful substances. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2- Can compare the materials used in the clinical biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Defines the cleaning materials used in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3.Laboratuarda kullanılan metal malzemeleri tanımlar. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Can compare the concepts of solution and concentration. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1.% explains how the solutions are prepared. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2.Explains how to prepare Molar and Normal solutions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.6.Discuss preanalytical, analytical and postanalytical errors. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.Explains phylebotomy and sample collection. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Applies phylebotomy and explains the relevant vascular anatomy. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2.Discuss infection control during phylebotomy. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3.Defines venous collection materials. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4.Defines what procedures can be performed on blood samples. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.5.Defines hemolysis. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.6.Defines the storage and transportation conditions of blood. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5-Can compare the instruments used in the biochemistry laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2.Can use precision scales and desiccators. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.1.Can perform measurements of carbohydrates in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.2.Makes measurements of lipids in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.3.Proteinlerin laboratuvarda ölçümlerini ve elektroforezini tanımlar. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.4.Discuss the measurement principles of enzymes. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 7-You can access printed and electronic information sources and learn about biochemistry and related fields. follows the developments. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1 defines the glass materials used in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.4. Defines filter papers and pH paper used in the laboratory. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3. Define isotonic and osmolar solutions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Defines buffer solutions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.5. Discusses pH measurement and its importance. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1. Can use distilled water device. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3. Applies spectrophotometric, colorimetric and photometric measurements. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.4. Explains the principle of the autoanalyzer used in clinical chemistry. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6. Can compare measurements of macromolecules in clinical biochemistry. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Laboratory accidents and precautions | 1, 2, 3, 4, 5 |
| 2 | Laboratrory materials and cleaning methods | 1, 2, 3, 4, 5 |
| 3 | Distilled, deionized water, weighing,cleaning in laboratory | 1, 2, 3, 4, 5 |
| 4 | Density and concentration of solutions | 1, 2, 3, 4, 5 |
| 5 | Molarity, normality and osmolarity | 1, 2, 3, 4, 5 |
| 6 | Acids, bases, and pH concepts, buffer systems | 1, 2, 3, 4, 5 |
| 7 | Laboratory tests using light intensity | 1, 2, 3, 4, 5 |
| 8 | Laboratory tests for low concentrations of substances | 1, 2, 3, 4, 5 |
| 9 | Protein electrophoresis | 1, 2, 3, 4, 5 |
| 10 | Biochemical tests per-patient | 1, 2, 3, 4, 5 |
| 11 | Sample collection and storage from body fluids | 1, 2, 3, 4, 5 |
| 12 | Anticoagulants in laboratory tests | 1, 2, 3, 4, 5 |
| 13 | Blood proteins, separation and measurement methods | 1, 2, 3, 4, 5 |
| 14 | Blood lipids separation and measurement methods | 1, 2, 3, 4, 5 |
| Resources |
| 1) Temel ve Uygulamalı Biyokimya Prof. Dr. Nesrin Emekli Academi Kitapevi Yayınları , 2) Öğrenciler için Biyokimya Laboratuarı Doç. Dr. Türkan Yiğitbaşı ve Prof.Dr.Nesrin Emekli , 3) Klinik Biyokimya Prof. Dr. Nesrin Emekli ve Doç. Dr. Türkan Yiğitbaşı Medipol Üniversitesi Yayınları, 4) Harper Biochemistry (Son Baskı), 5) Kolay Biyokimya (Batırel ve ark.) |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows the biochemical macromolecular metabolism. Applies and advances the knowlegde. | X | |||||
| 2 | Knows the principles of routine and research oriented biochemical technologies. | X | |||||
| 3 | Practical Laboratory Applications (Sampling conditions of various body fluids and tissue samples in health and disease states, reasons of analytical errors, storage conditions of samples,working principles of technologies used in routine and research based studies, determinig reference values.) | X | |||||
| 4 | Knows basic biostatistics methods, applies to experimental study results and evaluates. | ||||||
| 5 | Knows how to use specific instruments in biochemistry | X | |||||
| 6 | Can access printeed and electronic literature and able to follow the advancements in biochemistry and related field. | ||||||
| 7 | Can integrate and interpret the knowledge gained in biochemistry with knowledge obtained in other fields and can generate new information. | X | |||||
| 8 | Independantly applies his/her theoretical knowledge, critical thinking skills to the area of study, evaluates the results and writes a report. | X | |||||
| 9 | Defines a technical or scientific problem either with the helpof an advisor or independently, can come up with proposals and solve when needed. | X | |||||
| 10 | Take on responsibility in collborative studies, contributes and work in harmony. | X | |||||
| 11 | Follows national and international literature in Biochemistry, presents the work in seminars or publishes in journals. | X | |||||
| 12 | Can evaluate and teach biochemical data collection, interpretation, application and decleration recpecting cultural, scientific, social and ethical values. | X | |||||
| 13 | Take responsibility in managing, evaluate the results according to the context of quality processes. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |