Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| HORMONES BIOCHEMISTRY I | - | Fall Semester | 2+0 | 2 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Gözde ÜLFER |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Gözde ÜLFER, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI |
| Assistant(s) | Prof.Dr.Nesrin Emekli, Assoc. Prof. Dr.Türkan Yiğitbaşı, Ass. Prof .Dr.Sibel Erdem |
| Aim | To understand biochemical structure and function of hormon and improves the analytical concepts with those knowledge. |
| Course Content | This course contains; Classification of Hormones,Secondary messengers and hormones relationship,Biyochemical structure of hormones,Hormone action mechanism,Action mechanism of hormon on the cell surface,Anterior pituitary hormones,Calcium metabolism, hormones,Pancreatic and gastrointestinal system hormones,Catecholamines,Action mechanism of hormone on the nuclear status,Thyroid hormones,Steroid hormones,Reproduction hormones,Key points on hormone structure and measurements. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1-Describes the classification and molecular structure of hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2-Explains cell signal transmission pathways. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Explains the tyrosine kinase pathway. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Defines the hormone producing organs along with their functions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1.Explains the functions and effects of hormones released from the pituitary and hypothalamus. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2.Describes the effects and functions of hormones released from the adrenal medulla and cortex. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3.Describes the biosynthesis, degradation and effects of catecholamines. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4-Explains replacement therapy related to hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Explains the replacement therapy of gonadal hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5-Explains the laboratory tests used in the evaluation of hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1.Questions the routine tests used for pituitary and hypothalamus hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.Question tests for thyroid evaluation | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.1.Can describe the hormone regulation | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1. Explains hormones according to the organ where they are secreted. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2. Identifies small molecular weight hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3. Identifies large molecular weight hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4. Describes local hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1. Explains cAMP signal transduction. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3. It defines the inositol phosphate pathway. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.4. Questions the effect of calcium on signal transduction pathways. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Describes the effects and functions of thyroid hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.5. Describes the effects and functions of ovarian and testicular hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.6. Analyzes the effect of hormones on pubertal development in males and females. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.7. Describes the control of hormones and anomalies in the menstrual cycle. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.8. Describes the hormonal effect on calcium and phosphate regulation. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2. Explains thyroid hormone replacement therapy. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3. Describes medical treatments that affect calcium metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4. Describes replacement therapy related to other hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2. Questions laboratory measurements regarding growth hormone and prolactin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3. Analyzes laboratory tests related to adrenal insufficiency. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.4. Describes and analyzes catecholamine measurements in urine and plasma. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.5. Questions the diagnosis of hypo and hyper gonadism | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.6. Explains the tests of thyroid hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.2. Questions down regulation in membrane receptors. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.3. Analyzes membrane receptor cycles. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.4. Explains the feedback control of hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Classification of Hormones | 1, 2, 3 |
| 2 | Secondary messengers and hormones relationship | 1, 2, 3 |
| 3 | Biyochemical structure of hormones | 1, 2, 3 |
| 4 | Hormone action mechanism | 1, 2, 3 |
| 5 | Action mechanism of hormon on the cell surface | 1, 2, 3 |
| 6 | Anterior pituitary hormones | 1, 2, 3 |
| 7 | Calcium metabolism, hormones | 1, 2, 3 |
| 8 | Pancreatic and gastrointestinal system hormones | 1, 2, 3 |
| 9 | Catecholamines | 1, 2, 3 |
| 10 | Action mechanism of hormone on the nuclear status | 1, 2, 3 |
| 11 | Thyroid hormones | 1, 2, 3 |
| 12 | Steroid hormones | 1, 2, 3 |
| 13 | Reproduction hormones | 1, 2, 3 |
| 14 | Key points on hormone structure and measurements | 1, 2, 3 |
| Resources |
| Henry's Clinical Diagnosis and Management by Laboratory Methods, |
| Temel ve Uygulamalı Biyokimya(Prof.Dr.Nesrin Emekli),Biyokimya(Prof.Dr.Fiğen Gürdöl,Prof.Dr.Evin Ademoğlu) |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows the biochemical macromolecular metabolism. Applies and advances the knowlegde. | ||||||
| 2 | Knows the principles of routine and research oriented biochemical technologies. | ||||||
| 3 | Practical Laboratory Applications (Sampling conditions of various body fluids and tissue samples in health and disease states, reasons of analytical errors, storage conditions of samples,working principles of technologies used in routine and research based studies, determinig reference values.) | ||||||
| 4 | Knows basic biostatistics methods, applies to experimental study results and evaluates. | ||||||
| 5 | Knows how to use specific instruments in biochemistry | ||||||
| 6 | Can access printeed and electronic literature and able to follow the advancements in biochemistry and related field. | ||||||
| 7 | Can integrate and interpret the knowledge gained in biochemistry with knowledge obtained in other fields and can generate new information. | ||||||
| 8 | Independantly applies his/her theoretical knowledge, critical thinking skills to the area of study, evaluates the results and writes a report. | ||||||
| 9 | Defines a technical or scientific problem either with the helpof an advisor or independently, can come up with proposals and solve when needed. | ||||||
| 10 | Take on responsibility in collborative studies, contributes and work in harmony. | ||||||
| 11 | Follows national and international literature in Biochemistry, presents the work in seminars or publishes in journals. | ||||||
| 12 | Can evaluate and teach biochemical data collection, interpretation, application and decleration recpecting cultural, scientific, social and ethical values. | ||||||
| 13 | Take responsibility in managing, evaluate the results according to the context of quality processes. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 14 | 6 | 84 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 2 | 2 | 4 | |||
| Presentation of Project / Seminar | 2 | 3 | 6 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 3 | 3 | |||
| General Exam | 1 | 4 | 4 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 129 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(129/30) | 4 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| HORMONES BIOCHEMISTRY I | - | Fall Semester | 2+0 | 2 | 5 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Elective |
| Course Coordinator | Assist.Prof. Gözde ÜLFER |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Sultan Sibel ERDEM, Assist.Prof. Gözde ÜLFER, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI |
| Assistant(s) | Prof.Dr.Nesrin Emekli, Assoc. Prof. Dr.Türkan Yiğitbaşı, Ass. Prof .Dr.Sibel Erdem |
| Aim | To understand biochemical structure and function of hormon and improves the analytical concepts with those knowledge. |
| Course Content | This course contains; Classification of Hormones,Secondary messengers and hormones relationship,Biyochemical structure of hormones,Hormone action mechanism,Action mechanism of hormon on the cell surface,Anterior pituitary hormones,Calcium metabolism, hormones,Pancreatic and gastrointestinal system hormones,Catecholamines,Action mechanism of hormone on the nuclear status,Thyroid hormones,Steroid hormones,Reproduction hormones,Key points on hormone structure and measurements. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1-Describes the classification and molecular structure of hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2-Explains cell signal transmission pathways. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.2.Explains the tyrosine kinase pathway. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3-Defines the hormone producing organs along with their functions. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.1.Explains the functions and effects of hormones released from the pituitary and hypothalamus. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.2.Describes the effects and functions of hormones released from the adrenal medulla and cortex. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.3.Describes the biosynthesis, degradation and effects of catecholamines. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4-Explains replacement therapy related to hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.1.Explains the replacement therapy of gonadal hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5-Explains the laboratory tests used in the evaluation of hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.1.Questions the routine tests used for pituitary and hypothalamus hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.Question tests for thyroid evaluation | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.1.Can describe the hormone regulation | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.1. Explains hormones according to the organ where they are secreted. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.2. Identifies small molecular weight hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.3. Identifies large molecular weight hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 1.4. Describes local hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.1. Explains cAMP signal transduction. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.3. It defines the inositol phosphate pathway. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 2.4. Questions the effect of calcium on signal transduction pathways. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.4. Describes the effects and functions of thyroid hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.5. Describes the effects and functions of ovarian and testicular hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.6. Analyzes the effect of hormones on pubertal development in males and females. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.7. Describes the control of hormones and anomalies in the menstrual cycle. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 3.8. Describes the hormonal effect on calcium and phosphate regulation. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.2. Explains thyroid hormone replacement therapy. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.3. Describes medical treatments that affect calcium metabolism. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 4.4. Describes replacement therapy related to other hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.2. Questions laboratory measurements regarding growth hormone and prolactin. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.3. Analyzes laboratory tests related to adrenal insufficiency. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.4. Describes and analyzes catecholamine measurements in urine and plasma. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.5. Questions the diagnosis of hypo and hyper gonadism | 10, 11, 16, 19, 6, 9 | A, D, E |
| 5.6. Explains the tests of thyroid hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.2. Questions down regulation in membrane receptors. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.3. Analyzes membrane receptor cycles. | 10, 11, 16, 19, 6, 9 | A, D, E |
| 6.4. Explains the feedback control of hormones. | 10, 11, 16, 19, 6, 9 | A, D, E |
| Teaching Methods: | 10: Discussion Method, 11: Demonstration Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Classification of Hormones | 1, 2, 3 |
| 2 | Secondary messengers and hormones relationship | 1, 2, 3 |
| 3 | Biyochemical structure of hormones | 1, 2, 3 |
| 4 | Hormone action mechanism | 1, 2, 3 |
| 5 | Action mechanism of hormon on the cell surface | 1, 2, 3 |
| 6 | Anterior pituitary hormones | 1, 2, 3 |
| 7 | Calcium metabolism, hormones | 1, 2, 3 |
| 8 | Pancreatic and gastrointestinal system hormones | 1, 2, 3 |
| 9 | Catecholamines | 1, 2, 3 |
| 10 | Action mechanism of hormone on the nuclear status | 1, 2, 3 |
| 11 | Thyroid hormones | 1, 2, 3 |
| 12 | Steroid hormones | 1, 2, 3 |
| 13 | Reproduction hormones | 1, 2, 3 |
| 14 | Key points on hormone structure and measurements | 1, 2, 3 |
| Resources |
| Henry's Clinical Diagnosis and Management by Laboratory Methods, |
| Temel ve Uygulamalı Biyokimya(Prof.Dr.Nesrin Emekli),Biyokimya(Prof.Dr.Fiğen Gürdöl,Prof.Dr.Evin Ademoğlu) |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows the biochemical macromolecular metabolism. Applies and advances the knowlegde. | ||||||
| 2 | Knows the principles of routine and research oriented biochemical technologies. | ||||||
| 3 | Practical Laboratory Applications (Sampling conditions of various body fluids and tissue samples in health and disease states, reasons of analytical errors, storage conditions of samples,working principles of technologies used in routine and research based studies, determinig reference values.) | ||||||
| 4 | Knows basic biostatistics methods, applies to experimental study results and evaluates. | ||||||
| 5 | Knows how to use specific instruments in biochemistry | ||||||
| 6 | Can access printeed and electronic literature and able to follow the advancements in biochemistry and related field. | ||||||
| 7 | Can integrate and interpret the knowledge gained in biochemistry with knowledge obtained in other fields and can generate new information. | ||||||
| 8 | Independantly applies his/her theoretical knowledge, critical thinking skills to the area of study, evaluates the results and writes a report. | ||||||
| 9 | Defines a technical or scientific problem either with the helpof an advisor or independently, can come up with proposals and solve when needed. | ||||||
| 10 | Take on responsibility in collborative studies, contributes and work in harmony. | ||||||
| 11 | Follows national and international literature in Biochemistry, presents the work in seminars or publishes in journals. | ||||||
| 12 | Can evaluate and teach biochemical data collection, interpretation, application and decleration recpecting cultural, scientific, social and ethical values. | ||||||
| 13 | Take responsibility in managing, evaluate the results according to the context of quality processes. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |