Course Program
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY & GENETICS | - | Yearly | 38+10 | - | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Esra ÇAĞAVİ |
| Name of Lecturer(s) | Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. İlyas ÖZÇİÇEK, Assist.Prof. Neşe AYŞİT, Prof.Dr. Kürşat ÖZDİLLİ, Assist.Prof. Elif Zeynep YILMAZ, Assist.Prof. Sven Pıerre L. VILAIN, Assist.Prof. Behnaz KARADOĞAN |
| Assistant(s) | |
| Aim | The aim of this course is to evaluate the concepts of medical biology and genetics at the cellular, molecular and functional levels that will form the basis of clinical and scientific studies in medicine, to establish a connection between homeostasis and intracellular molecular mechanisms in various pathologies, and to evaluate the biology and genetics information at an interpretative level towards student competence and learning objectives for medical education. |
| Course Content | This course contains; Fundamentals of Life: The cell and biosynthesis,Proteins: Structure and function ,Genetic material of the cell: DNA, chromosomes, genome,DNA replication and repair ,RNA structure and functions, transcription,Genetic code and translation,Gen anlatımının kontröl mekanizmaları ve Epigenetik,Lab-1: The laboratory guidelines, micropipette practice, practice in SDS-PAGE ,Lab-2: DNA isolation from blood and Polimerase Chain Reaction (PCR),Lab-3: DNA restriction digestion and Agarose gel electrophoresis,Membrane Structures and Functions,Intracellular compartments: Organelles,Intracellular protein transport and vesicular transport,Endocytosis, exocytosis and membrane trafficking,Cell signaling- I,Cell signaling-II,Cytoskeleton and Motor Proteins,Lab-4: Floresans Microscopy: Immunocytochemical observation of the cell ,Cell Adhesion and Extracellular Matrix,Cell cycle,Cell senescence and Cell death,Stem cell and regeneration,Cancer biology and molecular basis of cancer,Lab-5: Cell culture applications. |
| Course Learning Outcomes | Teaching Methods | Assessment Methods |
| 3 | C |
| Teaching Methods: | 3: Problem Baded Learning Model |
| Assessment Methods: | C: Multiple-Choice Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Fundamentals of Life: The cell and biosynthesis | |
| 2 | Proteins: Structure and function | |
| 3 | Genetic material of the cell: DNA, chromosomes, genome | |
| 4 | DNA replication and repair | |
| 5 | RNA structure and functions, transcription | |
| 6 | Genetic code and translation | |
| 7 | Gen anlatımının kontröl mekanizmaları ve Epigenetik | |
| 8 | Lab-1: The laboratory guidelines, micropipette practice, practice in SDS-PAGE | |
| 9 | Lab-2: DNA isolation from blood and Polimerase Chain Reaction (PCR) | |
| 10 | Lab-3: DNA restriction digestion and Agarose gel electrophoresis | |
| 11 | Membrane Structures and Functions | |
| 12 | Intracellular compartments: Organelles | |
| 13 | Intracellular protein transport and vesicular transport | |
| 14 | Endocytosis, exocytosis and membrane trafficking | |
| 15 | Cell signaling- I | |
| 16 | Cell signaling-II | |
| 17 | Cytoskeleton and Motor Proteins | |
| 18 | Lab-4: Floresans Microscopy: Immunocytochemical observation of the cell | |
| 19 | Cell Adhesion and Extracellular Matrix | |
| 20 | Cell cycle | |
| 21 | Cell senescence and Cell death | |
| 22 | Stem cell and regeneration | |
| 23 | Cancer biology and molecular basis of cancer | |
| 24 | Lab-5: Cell culture applications |
| Resources |
| 1. Essential Cell Biology, Fifth Edition, Alberts et al, Garland Science Publishing, 2019 2. Molecular Biology of the Cell, Sixth Edition; Alberts et al, Garland Science Publishing, 2017 |
| Lecture notes, shared slides and animations. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | ||||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | ||||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | ||||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | ||||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | ||||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | ||||||
| 9 | Plans and conducts an advanced study on health independently. | ||||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | ||||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | ||||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | ||||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | ||||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | ||||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | ||||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | ||||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 24 | 2 | 48 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 20 | 20 | |||
| General Exam | 0 | 0 | 0 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 68 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(68/30) | 2 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| MEDICAL BIOLOGY & GENETICS | - | Yearly | 38+10 | - | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Esra ÇAĞAVİ |
| Name of Lecturer(s) | Prof.Dr. Esra ÇAĞAVİ, Assoc.Prof. İlyas ÖZÇİÇEK, Assist.Prof. Neşe AYŞİT, Prof.Dr. Kürşat ÖZDİLLİ, Assist.Prof. Elif Zeynep YILMAZ, Assist.Prof. Sven Pıerre L. VILAIN, Assist.Prof. Behnaz KARADOĞAN |
| Assistant(s) | |
| Aim | The aim of this course is to evaluate the concepts of medical biology and genetics at the cellular, molecular and functional levels that will form the basis of clinical and scientific studies in medicine, to establish a connection between homeostasis and intracellular molecular mechanisms in various pathologies, and to evaluate the biology and genetics information at an interpretative level towards student competence and learning objectives for medical education. |
| Course Content | This course contains; Fundamentals of Life: The cell and biosynthesis,Proteins: Structure and function ,Genetic material of the cell: DNA, chromosomes, genome,DNA replication and repair ,RNA structure and functions, transcription,Genetic code and translation,Gen anlatımının kontröl mekanizmaları ve Epigenetik,Lab-1: The laboratory guidelines, micropipette practice, practice in SDS-PAGE ,Lab-2: DNA isolation from blood and Polimerase Chain Reaction (PCR),Lab-3: DNA restriction digestion and Agarose gel electrophoresis,Membrane Structures and Functions,Intracellular compartments: Organelles,Intracellular protein transport and vesicular transport,Endocytosis, exocytosis and membrane trafficking,Cell signaling- I,Cell signaling-II,Cytoskeleton and Motor Proteins,Lab-4: Floresans Microscopy: Immunocytochemical observation of the cell ,Cell Adhesion and Extracellular Matrix,Cell cycle,Cell senescence and Cell death,Stem cell and regeneration,Cancer biology and molecular basis of cancer,Lab-5: Cell culture applications. |
| Course Learning Outcomes | Teaching Methods | Assessment Methods |
| 3 | C |
| Teaching Methods: | 3: Problem Baded Learning Model |
| Assessment Methods: | C: Multiple-Choice Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Fundamentals of Life: The cell and biosynthesis | |
| 2 | Proteins: Structure and function | |
| 3 | Genetic material of the cell: DNA, chromosomes, genome | |
| 4 | DNA replication and repair | |
| 5 | RNA structure and functions, transcription | |
| 6 | Genetic code and translation | |
| 7 | Gen anlatımının kontröl mekanizmaları ve Epigenetik | |
| 8 | Lab-1: The laboratory guidelines, micropipette practice, practice in SDS-PAGE | |
| 9 | Lab-2: DNA isolation from blood and Polimerase Chain Reaction (PCR) | |
| 10 | Lab-3: DNA restriction digestion and Agarose gel electrophoresis | |
| 11 | Membrane Structures and Functions | |
| 12 | Intracellular compartments: Organelles | |
| 13 | Intracellular protein transport and vesicular transport | |
| 14 | Endocytosis, exocytosis and membrane trafficking | |
| 15 | Cell signaling- I | |
| 16 | Cell signaling-II | |
| 17 | Cytoskeleton and Motor Proteins | |
| 18 | Lab-4: Floresans Microscopy: Immunocytochemical observation of the cell | |
| 19 | Cell Adhesion and Extracellular Matrix | |
| 20 | Cell cycle | |
| 21 | Cell senescence and Cell death | |
| 22 | Stem cell and regeneration | |
| 23 | Cancer biology and molecular basis of cancer | |
| 24 | Lab-5: Cell culture applications |
| Resources |
| 1. Essential Cell Biology, Fifth Edition, Alberts et al, Garland Science Publishing, 2019 2. Molecular Biology of the Cell, Sixth Edition; Alberts et al, Garland Science Publishing, 2017 |
| Lecture notes, shared slides and animations. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | ||||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | ||||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | ||||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | ||||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | ||||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | ||||||
| 9 | Plans and conducts an advanced study on health independently. | ||||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | ||||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | ||||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | ||||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | ||||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | ||||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | ||||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | ||||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |