Course Program
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| EVIDENCE BASED MEDICINE | TP5015577 | Yearly | 40+45 | - | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Practice |
| Course Coordinator | Assoc.Prof. Perihan TORUN |
| Name of Lecturer(s) | Assist.Prof. Ömer ATAÇ, Assist.Prof. Ayşe Nur BALCI, Assist.Prof. Ayşe Zülal TOKAÇ FARIMAZ, Assoc.Prof. Perihan TORUN, Assist.Prof. Ayşe Gül YÜCESAN |
| Assistant(s) | |
| Aim | To learn the methods of finding and using the current best evidence in decision-making in medicine in conjunction (together) with expertise of the decision-makers and expectations and values of the patients/people. |
| Course Content | This course contains; Meeting and expectations Evidence-Based Medicine: Introduction Data, Information-Knowledge and Evidence concepts,Producing Evidence: Observational Studies,Producing Evidence: Experimental Studies,Evidence Finding: International Data and Information Sources,Systematic Reviews,Meta-Analysis,Risk Calculations,Sensitivity, Selectivity, Predictive Value Calculations,Validity, Reliability calculations, Research errors. |
| Course Learning Outcomes | Teaching Methods | Assessment Methods |
| Defines the Evidence-Based Medicine. | 10, 16, 5, 6, 9 | A, D |
| Explains the difference between evidence, data, information, knowledge. | 10, 16, 5, 6, 9 | A, D |
| Lists the ways of production of and access to evidence. | 10, 16, 5, 6, 9 | A, D |
| Understands the importance of following the literature while practicing medicine. | 10, 16, 5, 6, 9 | A, D |
| Sorts different types of studies by the value of the evidence they provide. | 10, 16, 5, 6, 9 | A, D |
| Compares the advantages and disadvantages of different types of research. | 10, 16, 5, 6, 9 | A, D |
| Counts the types of observational studies used to produce evidence. | 10, 16, 5, 6, 9 | A, D |
| Plans an observational study. | 10, 16, 5, 6, 9 | A, D |
| Lists the types of experimental research used to produce evidence. | 10, 16, 5, 6, 9 | A, D |
| Plans an experimental study. | 10, 16, 5, 6, 9 | A, D |
| Accesses and uses international evidence-based medical databases. | 10, 16, 5, 6, 9 | A, D |
| Finds the most up-to-date evidence needed during medical practice. | 10, 16, 5, 6, 9 | A, D |
| Describes the logic of the systematic review. | 10, 16, 5, 6, 9 | A, D |
| Interprets systematic review articles. | 10, 16, 5, 6, 9 | A, D |
| Describes meta-analysis logic. | 10, 16, 5, 6, 9 | A, D |
| Interprets meta-analysis articles. | 10, 16, 5, 6, 9 | A, D |
| Defines related measures related to health and disease. | 10, 16, 5, 6, 9 | A, D |
| Interprets related measures related to health and disease. | 10, 16, 5, 6, 9 | A, D |
| Performs common risk calculations. | 10, 16, 5, 6, 9 | A, D |
| Defines sensitivity, specificity, and predictive value. | 10, 16, 5, 6, 9 | A, D |
| Interprets sensitivity, specificity, and predictive value. | 10, 16, 5, 6, 9 | A, D |
| Calculates the accuracy values of diagnostic tests. | 10, 16, 5, 6, 9 | A, D |
| Critically appraises research methods. | 10, 16, 5, 6, 9 | A, D |
| Identifies biases in the studies. | 10, 16, 5, 6, 9 | A, D |
| Explains the meaning of the scientific terms in medical studies. | 10, 16, 5, 6, 9 | A, D |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 5: Cooperative Learning, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Meeting and expectations Evidence-Based Medicine: Introduction Data, Information-Knowledge and Evidence concepts | |
| 2 | Producing Evidence: Observational Studies | |
| 3 | Producing Evidence: Experimental Studies | |
| 4 | Evidence Finding: International Data and Information Sources | |
| 5 | Systematic Reviews | |
| 6 | Meta-Analysis | |
| 7 | Risk Calculations | |
| 8 | Sensitivity, Selectivity, Predictive Value Calculations | |
| 9 | Validity, Reliability calculations, Research errors |
| Resources |
| 1. Cochrane Collaboration. Cochrane Library, 2021. http://www.cochranelibrary.com 2. Hayran O, Özbek H. Sağlık Bilimlerinde Araştırma ve İstatistik Yöntemler (SPSS Uygulama Örnekleri ile Genişletilmiş 2. Baskı) Nobel Tıp Kitabevleri, İstanbul, 2017 3. Palmas WR. Pocket Evidence Based Medicine: A Survival Guide for Clinicians and Students. Springer, New York, 2023. https://doi.org/10.1007/978-3-031-19471-9 4. Straus SE, Glasziou P, Richardson WS, Haynes RB. Evidence-Based Medicine: How to Practice and Teach EBM. 5th ed., 2018. 5. Goodman MS. Biostatistics for Clinical and Public Health Research. Routledge, New York, 2017. 6. Bruce N. Quantitative Methods for Health Research: a practical interactive guide to epidemiology and statistics. Second ed., NJ:Wiley, 2018. 7. Greenhalgh T. How to read a paper: the basics of evidence-based medicine. Wiley, 2014. 8. Egger M, Higgins JPT, Smith GD (editors). Systematic Reviews in Health ResearchMeta-Analysis in Context. Third ed., BMJ Books, John Wiley & Sons, 2022. 9. Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ. 1996 Jan 13;312(7023):71-2. doi:10.1136/bmj.312.7023.71. 10. https://researchguides.dartmouth.edu/c.php?g=944702&p=6833672 11.Prasad K. Fundamentals of Evidence-Based Medicine. 2nd edition. Springer, India, 2013. 12. Goldstein NE, Morrison RS. Evidence-Based Practice of Palliative Medicine. Elsevier Saunders, 2013. 13. Khan K, Kunz R, Kleijnen J, Antes G. Systematic reviews to support evidence-based medicine. 2nd edition, Hodder Arnold an Hachette UK Company, 2011. 14. Mayer D. Essentials evidence-based medicine. 2nd edition, Cambridge University Press, 2010. 15. Hayran O. Güncel Epidemiyoloji. Medipol Üniversiteis Yayınları, İstanbul, 2023. 16. STROBE Checklists (von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet. 2007 Oct 20;370(9596):1453-7. doi: 10.1016/S0140-6736(07)61602-X. PMID: 18064739.) 17. CONSORT checklist of information to include when reporting a randomised trial. (Schulz KF, Altman DG, Moher D; CONSORT Group. CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med. 2010 Jun 1;152(11):726-32. doi: 10.7326/0003-4819-152-11-201006010-00232. Epub 2010 Mar 24. PMID: 20335313.) 18. PRISMA - Preferred Reporting Items for Systematic Reviews and Meta-Analyses (Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021 Mar 29;372:n71. doi: 10.1136/bmj.n71. PMID: 33782057; PMCID: PMC8005924.) |
| Lecture notes, Powerpoint presentations, Relevant web pages |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | X | |||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | X | |||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | X | |||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | X | |||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | X | |||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | X | |||||
| 21 | Has adequate awareness on occupational health and safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 30 | 1 | 30 | |||
| Guided Problem Solving | 4 | 2 | 8 | |||
| Resolution of Homework Problems and Submission as a Report | 1 | 34 | 34 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 0 | 0 | 0 | |||
| General Exam | 48 | 1 | 48 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 120 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(120/30) | 4 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| EVIDENCE BASED MEDICINE | TP5015577 | Yearly | 40+45 | - | 4 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Practice |
| Course Coordinator | Assoc.Prof. Perihan TORUN |
| Name of Lecturer(s) | Assist.Prof. Ömer ATAÇ, Assist.Prof. Ayşe Nur BALCI, Assist.Prof. Ayşe Zülal TOKAÇ FARIMAZ, Assoc.Prof. Perihan TORUN, Assist.Prof. Ayşe Gül YÜCESAN |
| Assistant(s) | |
| Aim | To learn the methods of finding and using the current best evidence in decision-making in medicine in conjunction (together) with expertise of the decision-makers and expectations and values of the patients/people. |
| Course Content | This course contains; Meeting and expectations Evidence-Based Medicine: Introduction Data, Information-Knowledge and Evidence concepts,Producing Evidence: Observational Studies,Producing Evidence: Experimental Studies,Evidence Finding: International Data and Information Sources,Systematic Reviews,Meta-Analysis,Risk Calculations,Sensitivity, Selectivity, Predictive Value Calculations,Validity, Reliability calculations, Research errors. |
| Course Learning Outcomes | Teaching Methods | Assessment Methods |
| Defines the Evidence-Based Medicine. | 10, 16, 5, 6, 9 | A, D |
| Explains the difference between evidence, data, information, knowledge. | 10, 16, 5, 6, 9 | A, D |
| Lists the ways of production of and access to evidence. | 10, 16, 5, 6, 9 | A, D |
| Understands the importance of following the literature while practicing medicine. | 10, 16, 5, 6, 9 | A, D |
| Sorts different types of studies by the value of the evidence they provide. | 10, 16, 5, 6, 9 | A, D |
| Compares the advantages and disadvantages of different types of research. | 10, 16, 5, 6, 9 | A, D |
| Counts the types of observational studies used to produce evidence. | 10, 16, 5, 6, 9 | A, D |
| Plans an observational study. | 10, 16, 5, 6, 9 | A, D |
| Lists the types of experimental research used to produce evidence. | 10, 16, 5, 6, 9 | A, D |
| Plans an experimental study. | 10, 16, 5, 6, 9 | A, D |
| Accesses and uses international evidence-based medical databases. | 10, 16, 5, 6, 9 | A, D |
| Finds the most up-to-date evidence needed during medical practice. | 10, 16, 5, 6, 9 | A, D |
| Describes the logic of the systematic review. | 10, 16, 5, 6, 9 | A, D |
| Interprets systematic review articles. | 10, 16, 5, 6, 9 | A, D |
| Describes meta-analysis logic. | 10, 16, 5, 6, 9 | A, D |
| Interprets meta-analysis articles. | 10, 16, 5, 6, 9 | A, D |
| Defines related measures related to health and disease. | 10, 16, 5, 6, 9 | A, D |
| Interprets related measures related to health and disease. | 10, 16, 5, 6, 9 | A, D |
| Performs common risk calculations. | 10, 16, 5, 6, 9 | A, D |
| Defines sensitivity, specificity, and predictive value. | 10, 16, 5, 6, 9 | A, D |
| Interprets sensitivity, specificity, and predictive value. | 10, 16, 5, 6, 9 | A, D |
| Calculates the accuracy values of diagnostic tests. | 10, 16, 5, 6, 9 | A, D |
| Critically appraises research methods. | 10, 16, 5, 6, 9 | A, D |
| Identifies biases in the studies. | 10, 16, 5, 6, 9 | A, D |
| Explains the meaning of the scientific terms in medical studies. | 10, 16, 5, 6, 9 | A, D |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 5: Cooperative Learning, 6: Experiential Learning, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Meeting and expectations Evidence-Based Medicine: Introduction Data, Information-Knowledge and Evidence concepts | |
| 2 | Producing Evidence: Observational Studies | |
| 3 | Producing Evidence: Experimental Studies | |
| 4 | Evidence Finding: International Data and Information Sources | |
| 5 | Systematic Reviews | |
| 6 | Meta-Analysis | |
| 7 | Risk Calculations | |
| 8 | Sensitivity, Selectivity, Predictive Value Calculations | |
| 9 | Validity, Reliability calculations, Research errors |
| Resources |
| 1. Cochrane Collaboration. Cochrane Library, 2021. http://www.cochranelibrary.com 2. Hayran O, Özbek H. Sağlık Bilimlerinde Araştırma ve İstatistik Yöntemler (SPSS Uygulama Örnekleri ile Genişletilmiş 2. Baskı) Nobel Tıp Kitabevleri, İstanbul, 2017 3. Palmas WR. Pocket Evidence Based Medicine: A Survival Guide for Clinicians and Students. Springer, New York, 2023. https://doi.org/10.1007/978-3-031-19471-9 4. Straus SE, Glasziou P, Richardson WS, Haynes RB. Evidence-Based Medicine: How to Practice and Teach EBM. 5th ed., 2018. 5. Goodman MS. Biostatistics for Clinical and Public Health Research. Routledge, New York, 2017. 6. Bruce N. Quantitative Methods for Health Research: a practical interactive guide to epidemiology and statistics. Second ed., NJ:Wiley, 2018. 7. Greenhalgh T. How to read a paper: the basics of evidence-based medicine. Wiley, 2014. 8. Egger M, Higgins JPT, Smith GD (editors). Systematic Reviews in Health ResearchMeta-Analysis in Context. Third ed., BMJ Books, John Wiley & Sons, 2022. 9. Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ. 1996 Jan 13;312(7023):71-2. doi:10.1136/bmj.312.7023.71. 10. https://researchguides.dartmouth.edu/c.php?g=944702&p=6833672 11.Prasad K. Fundamentals of Evidence-Based Medicine. 2nd edition. Springer, India, 2013. 12. Goldstein NE, Morrison RS. Evidence-Based Practice of Palliative Medicine. Elsevier Saunders, 2013. 13. Khan K, Kunz R, Kleijnen J, Antes G. Systematic reviews to support evidence-based medicine. 2nd edition, Hodder Arnold an Hachette UK Company, 2011. 14. Mayer D. Essentials evidence-based medicine. 2nd edition, Cambridge University Press, 2010. 15. Hayran O. Güncel Epidemiyoloji. Medipol Üniversiteis Yayınları, İstanbul, 2023. 16. STROBE Checklists (von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet. 2007 Oct 20;370(9596):1453-7. doi: 10.1016/S0140-6736(07)61602-X. PMID: 18064739.) 17. CONSORT checklist of information to include when reporting a randomised trial. (Schulz KF, Altman DG, Moher D; CONSORT Group. CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med. 2010 Jun 1;152(11):726-32. doi: 10.7326/0003-4819-152-11-201006010-00232. Epub 2010 Mar 24. PMID: 20335313.) 18. PRISMA - Preferred Reporting Items for Systematic Reviews and Meta-Analyses (Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021 Mar 29;372:n71. doi: 10.1136/bmj.n71. PMID: 33782057; PMCID: PMC8005924.) |
| Lecture notes, Powerpoint presentations, Relevant web pages |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | X | |||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | X | |||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | X | |||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | X | |||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | X | |||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | X | |||||
| 21 | Has adequate awareness on occupational health and safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |