Geri
AKADEMİK

(Liste, ünvan ve isme göre alfabetik olarak sıralanmıştır.)

Kurum İçi Görevlendirme

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Adı Soyadı Prof.Dr. Lütfü HANOĞLU
E-Posta lhanoglu@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Prof.Dr. Gürkan ÖZTÜRK
E-Posta gozturk@medipol.edu.tr
Detay Öz Geçmiş
Medya

Hacettepe Üniversitesi 1993 King's College London

Daha Önce Görev Yaptığı Yerler

Yüzüncü Yıl Üniversitesi

Araştırma Alanları

Nörodejeneratif ve nörorejeneratif süreçlerde etkin olan moleküler ve hücresel mekanizmaların anlaşılmasında hücre kültürü ve hayvan modelleriyle araştırmalar yapmaktadır. Bir başka uzmanlık alanı ileri mikroskopik görüntüleme ve manipülasyon teknikleridir.

Seçili Yayınları / Tüm Yayınları

Aydin, M.S., Yigit, E.N., Vatandaslar, E., Erdogan, E. & Ozturk, G. (2018) Transfer and Integration of Breast Milk Stem Cells to the Brain of Suckling Pups. Sci Rep, 8, 14289.
Aysit-Altuncu, N., Ulusoy, C., Ozturk, G. & Tuzun, E. (2018) Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study. Neuroreport, 29, 932-938.
Bal, R., Ozturk, G., Etem, E.O., Him, A., Cengiz, N., Kuloglu, T., Tuzcu, M., Yildirim, C. & Tektemur, A. (2018) Modulation of Excitability of Stellate Neurons in the Ventral Cochlear Nucleus of Mice by ATP-Sensitive Potassium Channels. J Membr Biol, 251, 163-178.
Demircan, T., Ovezmyradov, G., Yildirim, B., Keskin, I., Ilhan, A.E., Fescioglu, E.C., Ozturk, G. & Yildirim, S. (2018) Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota. Sci Rep, 8, 10974.
Kuter, N., Aysit-Altuncu, N., Ozturk, G. & Ozek, E. (2018) The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in vitro. Neonatology, 113, 360-365.
Caglayan, B., Caglayan, A.B., Beker, M.C., Yalcin, E., Beker, M., Kelestemur, T., Sertel, E., Ozturk, G., Kilic, U., Sahin, F. & Kilic, E. (2017) Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice. Experimental neurology, 296, 23-31.
Demircan, T., Keskin, I., Dumlu, S.N., Ayturk, N., Avsaroglu, M.E., Akgun, E., Ozturk, G. & Baykal, A.T. (2017) Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database. Proteomics, 17.
Shahbazi, R., Ozcicek, I., Ozturk, G. & Ulubayram, K. (2017) Functionalized gold nanoparticles manifested as potent carriers for nucleolar targeting. Nanotechnology, 28, 025103.
Demircan, T., Ilhan, A.E., Ayturk, N., Yildirim, B., Ozturk, G. & Keskin, I. (2016) A histological atlas of the tissues and organs of neotenic and metamorphosed axolotl. Acta Histochem, 118, 746-759.
Kilic, E., Reitmeir, R., Kilic, U., Caglayan, A.B., Beker, M.C., Kelestemur, T., Ethemoglu, M.S., Ozturk, G. & Hermann, D.M. (2014) HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia. Front Cell Neurosci, 8, 422.
Bektas, S. & Ozturk, G. (2013) Enhancement of cultured adult motor neuron survival with cold pre-incubation. Neurosci Lett, 533, 23-27.
Ozturk, G., Cengiz, N., Erdogan, E., Him, A., Oguz, E.K., Yenidunya, E. & Aysit, N. (2013) Two distinct types of dying back axonal degeneration in vitro. Neuropathol Appl Neurobiol, 39, 362-376.
Cengiz, N., Ozturk, G., Erdogan, E., Him, A. & Oguz, E.K. (2012) Consequences of neurite transection in vitro. J Neurotrauma, 29, 2465-2474.
Demir, O., Aysit, N., Onder, Z., Turkel, N., Ozturk, G., Sharrocks, A.D. & Kurnaz, I.A. (2011) ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target. Biochimica et biophysica acta, 1812, 652-662.

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Adı Soyadı Prof.Dr. Ahmet Zeki ŞENGİL
E-Posta asengil@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Nozokomial infeksiyonlar, hepaptitis serolojisi, paramagnetic substanslar ve immun modulasyon, resistan tuberculoz ve immunite, nanopartiküller ve antimikrobiyal aktivity,

Seçili Yayınları / Tüm Yayınları

Sengil AZ, Akkaya H, Gonenc M, Gonenc D, Ozkan D. Species composition and monthly distribution of mosquito (Culicidae) larvae in the Istanbul metropolitan area, Turkey. Int J Biol Med Res. 2011; 2(1): 415-424

Valério P, Góes AM, Karacayli U, Gunduz O, Salman S, Sengil AZ, Yilmaz S, Agathopoulos S, Oktar FN. Influence of boroxide bioactive bioglasses (BBB) on osteoblast viability. RMN. Jorge, SM. Santos, JMRS. Tavares, MAP. Vaz and JCR Capos (Eds.). Biodental Engineering, CRC Press, London, 2009, pp 99-103

Karacayli U, Gunduz O, Salman S, Ozyegin LS, Sengil AZ, Agathopoulos S, Oktar FN. ‘’Effect of sintering temperature on mechanical and microstructural properties of zeolite (clinoptilolite) reinforced bovine hydroxyapatite (BHA) composites’’ . RMN. Jorge, SM. Santos, JMRS. Tavares, MAP. Vaz and JCR Capos (Eds.). Biodental Engineering, CRC Press, London, 2009, pp 105-108

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Adı Soyadı Prof.Dr. Türkan YİĞİTBAŞI
E-Posta tyigitbasi@medipol.edu.tr
Detay Öz Geçmiş
Medya

Eğe Üniversitesi 1988 Erciyes Üniversitesi Tıbbi Biyokimya

Daha Önce Görev Yaptığı Yerler

Erciyes Üniversitesi,Kayseri Devlet Hastanesi,Analiz Tanı Merkezi,Baylor College of Medicine,İzmir Bölge Hıfzısıhha Enstitüsü,İzmir Katip Çelebi Atatürk Eğitim ve Araştırma Hastanesi

Araştırma Alanları

Üreme ve Obesite Biyokimyası,Çoklu Yöntemlerin Klinik Uygulamaları,Oksijen Radikalleri,Klinik biyokimya

Seçili Yayınları / Tüm Yayınları

1.A new method in systemic autoimmune diseases diagnosis: Multiplex test system and method performances” Y.BASKIN, G. AFACAN, S.S. ERKUNT, T. YİĞİTBAŞI Turkish Journal of Biochemistry 2008; 33 (1):19-24.
2.Type 2 diabetes mellitus patients with good or poor glycaemic management: relationship between nitric oxide, growth hormone, lipid profile and HbA1c levels” Y. BASKIN, T. YİĞİTBAŞI, G. AFACAN Türkiye Klinikleri Journal of Cardiovascular Sciences 2009; 21 (2):153-9.
3.Relationship Between The Levels of Growth Hormone, Leptin, Amylin, Glucagon Like Peptide-1 and Insulin Resistance in Obese Patients” Türkan Yiğitbaşı, Yasemin Baskın, Gökhan Afacan,Ayşın Harmanda Turkish Journal of Biochemistry–Turk J Biochem 2010; 35 (3) ; 177–182.
4.Eotaxin and Interleukin-4 Levels and Their Relation to Sperm Parameters in Infertile Men". Turkan Yigitbasi, Yasemin Baskin, Gokan Afacan ,Fusun Karaarslan, Cevat Taheri, Dilek Aslan Turkısh Journal Of Medıcal Scıences, 2010; Cilt: 30, No: 5, Sf: 1441-1447.
5.Reference Intervals For Serum Immunoglobulın (Iga, Igg, Igm) And Igg Subclasses In Healthy Subjects” Yasemin Baskın, Türkan Yiğitbaşı, Gökhan Afacan, Filiz Akgün, Rabia Dere. Turkish Journal of Biochemistry,2010; Cilt: 35, No: 4, Sf: 325-332.
6.Clinical Proteomics of Breast Cancer” Yasemin Baskın, Türkan Yiğitbaşı Current Genomics, 2010, 11,528-536.
7.The Evaluatıon Of Total Antıoxıdant And Oxıdant Response In Semınal Plasma From Fertıle And Infertıle Men Usıng A Novel Automated Method” Türkan Yiğitbaşı, Yasemin Baskın, Hakim Çelik, Füsun Karaarslan, Cevat Taheri, Gökhan Afacan, Dilek Aslan ,Özcan Erel. Turkısh Journal Of Medıcal Scıences, 2011,31 (1); 61-67.
8.The value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer” K Atahan, H. Küpeli, S. Gür, T. Yiğitbaşı, Y. Baskın, S. Yiğit, M. Deniz, A. Çökmez, E. Tarcan. Int. J. Med. Sci, 2011;8(2):148-155

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Adı Soyadı Prof.Dr. Bayram Ufuk ŞAKUL
E-Posta usakul@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Nöroanatomi, Hafıza ve Öğrenme, Columna vertebralis, Kalp, Karaciğer mimarisi, Paranasal sinüsler, Cone-Beam Tomografi

Seçili Yayınları / Tüm Yayınları

KİTAPLAR

1. Şakul, U.: Baş ve Boynun Topografik Anatomisi. Ankara Üniversitesi Basımevi, 1999. (ISBN 975-94242-0-7)
2. Şakul, U.: TUS için Anatomi. Ankara Üniversitesi Basımevi, 2001. (ISBN 975-94242-1-5)
3. Şakul, U.: (Bölüm Yazarlığı) Wolf-Heidegger’in İnsan Anatomisi Atlası, Güneş Kitabevi Ltd. Şti. 2001. (ISBN 975-8531-13-1)
4. Şakul, U.: (Bölüm Yazarlığı) Korrelatif Nöroanatomi, Nobel Tıp Kitapevleri, 2002. (ISBN 975-420-216-6)
5. Şakul, U.: (Bölüm Yazarlığı) Göğüs Cerrahisi, Sim Matbaacılık Ltd.Şti, 2003. (ISBN 975-92200-0-8)
6. Şakul, U.: (Bölüm Yazarlığı) Netter İnsan Anatomi Atlası, 3. baskı, Nobel Tıp Kitapevleri, 2005. (ISBN 1-929007-11-6)
7. Şakul, B.U.: (Bölüm Yazarlığı) Temel Klinik Anatomi, 2. Baskı, Güneş Kitapevi, 2006. (ISBN 975-277-074-6)
8. Şakul, U.: Anatomi. Melike Ofset Basımevi, 2007. (ISBN 978-9424-22-0)
9. Şakul, U., Bilecenoğlu, B. : (Bölüm Yazarlığı) Pelvis ve Perine Anatomisi, Prostat Hastalıkları Kitabı, Güneş Tıp Kitapevleri, 2008. (ISBN 978-975-277-184-0).
10. Şakul, U., Bilecenoğlu, B. : (Bölüm Yazarlığı) Prostat Bezi Anatomisi, Prostat Hastalıkları Kitabı, Güneş Tıp Kitapevleri, 2008. (ISBN 978-975-277-184-0).
11. Şakul, U., Bilecenoğlu, B. : Baş ve Boynun Klinik Bölgesel Anatomisi. Özkan Matbaacılık, 2009. (ISBN 978-975-94242-2-0).
12. Şakul, U.: (Bölüm Yazarlığı) Woelfel’in Diş Anatomisi-Diş Hekimliği ile İlişkisi, Güneş Tıp Kitapevleri, 2010. (ISBN 978-0-7817-6860-3)

MAKALELER

1. İslam, C., Şakul, U., Güzel, B.: Real minimal diameter of the lower thoracic and lumbar vertebral pedicles. Clinical Anatomy, 7:271-274, 1994.
2. Güzel, B., Şakul, U., İslam, C., Köse, K.: A new method for differentiation of lumbar vertebrae. The Jikeikai Medical Journal, 41(2):111-116, 1994.
3. Şakul, U., İslam, C., Güzel, B.: The location and the number of nutrient foramina on the shafts of the upper limb bones. The Jikeikai Medical Journal, 41(2):117-122, 1994.
4. Şakul, U., Güzel, B., İslam, C.: The location and the number of nutrient foramina on the shafts of the lower limb bones. Acta Anatomica Nipponica, 69(4):410-411, 1994.
5. İslam, C., Güzel, B., Şakul, U.: Clinical importance of the minimal cancellous diameter of lower thoracic and lumbar vertebral pedicles. Clinical Anatomy, 9:151-154, 1996.
6. Aydınlıoğlu, A., Şakul, U., Diyarbakırlı, S.: A rare insertion site for abductor pollicis longus and extensor pollicis brevis muscles. Acta Anatomica, 163: 229-232, 1998.
7. Orhan. K., İçen. M., Bilecenoğlu, B., Şakul, BU,: Effect of third molar on the morphology of the pterygopalatine canal: a cone beam computed tomography study. Int J of Computer Assisted Radiol and Surgery, 5 (Suppl):S235-S240, 2010.
8.Orhan. K., Aksoy, S., Bilecenoğlu, B., Şakul, BU, Paksoy, CS.: Evaluation of bifid mandibular canals with cone-beam computed tomography in a Turkish adult population: a retrospective study. Surg Radiol Anat, 33:501-507, 2011.
9.Orhan. K., Şakul, BU, Öz, U., Bilecenoğlu, B.: “Investigation of pterygoid hamulus morphology using cone beam CT: preliminary results.”, Int J of Computer Assisted Radiol and Surg., 6 (Suppl 1): 382-383, 2011.
10. Orhan K, Icen M, Bilecenoglu B, Sakul BU, Kose SK.: The effect of posterior wall of maxillary sinus thickness on the morphology of the pterygopalatine canal.”, Int J of Computer Assisted Radiol and Surgery, 6 (Suppl 1): 383-384, 2011.
11. Orhan. K., Şakul, BU, Öz, U., Bilecenoğlu, B.: “Evaluation of pterygoid hamulus morphology using cone beam computed tomography.”, Oral Surg Oral Med Orak Pathol Oral Radiol Endod, 112:e48-e55, 2011.
12. Ozan, O., Orhan, K., Aksoy, S., İçen, M., Bilecenoğlu, B., Sakul, B.U.: The effect of removable partial dentures on alveolar bone resorption: A retrospective study with cone-beam computed tomography. Journal of Prosthodontics, 00:1-7, 2012.
13. Bilecenoglu, B., Onul, M., Altay, O.T., Sakul B.U: Cervicofacial emphysema after dental treatment with emphasis on the anatomy of the cervical fascia. The Journal of Craniofacial Surgery, Vol.23, Number 6, 544-548, Nov. 2012.
14. Şakul, U., Güzel, B., İslam, C., Köse, K.: Morphometry of lower thoracic and lumbar vertebrae (A clinicoanatomical study). The Italian Journal of Orthopaedics and Traumatology, 22(2):253-260, 1996.
15. Arıncı, K., Şakul, U., Elhan, A., Karan, O.: Brodmann'a göre cortex cerebri'nin topografik haritası (1-6. sahaların önem ve fonksiyonları). Optimal Tıp Dergisi, 1(1):33-39, 1989.
16. Arıncı, K., Şakul, U., Elhan, A., Karan, O.: Brodmann'a göre cortex cerebri'nin topografik haritası (7-52. sahaların önem ve fonksiyonları). Optimal Tıp Dergisi, 2(1):27-33, 1989.
17. Şakul, U., Elhan, A., Karan, O.: Dominant subkortikal yapıların lisandaki rolü. Nöroloji, 18(1):87-104, 1991.
18. Şakul, U., Türkaslan, K.: Variations of the median and the musculocutaneous nerves. Journal of Ankara Medical School, 13(3):259-262, 1991.
19. Şakul, U., Akbay, C., Acar, R.: Globus pallidus nöronlarının morfolojik tanımlanması: Işık mikroskobik bir çalışma. Optimal Tıp Dergisi, 4(4):183-188, 1991.
20. Acar, R., Şakul, U., Türkaslan, K., Ercan, A.: Fissura pterygomaxillaris'in şekil varyasyonları ve bunun klinik önemi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 44:537-544, 1991.
21. İslam, C., Şakul, U., Güzel, B.: Ön arka ve Mortis filmlerinde ayak bileği eklemi eksenlerinin karşılaştırılması. Van Tıp Dergisi, 1(2):19-22, 1994.
22. Şakul, U., Acar, R., Erdemli, E.: Erişkin insanlarda nervus trigeminus ve dallarının akson sayıları. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 1:39-41, 1994.
23. Aydınlıoğlu, A., Diyarbakırlı, S., Şakul, U., Keleş, P., Kırış, M., Erdoğan, A.: Burun dış duvarı anatomisinin sinus cerrahisi açısından incelenmesi. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 2:89-94, 1996.
24. Aydınlıoğlu, A., Diyarbakırlı, S., Şakul, U., Keleş, P., Arslan, H., Kırış, M.: Paranasal sinuslerin cerrahi anatomisi: Kadavra ve CT araştırması. I- Sinus maxillaris ve frontalis. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 3:6-11, 1997.
25. Aydınlıoğlu, A., Diyarbakırlı, S., Şakul, U., Keleş, P., Arslan, H., Kırış, M.: Paranasal sinuslerin cerrahi anatomisi: Kadavra ve CT araştırması. II- Sinus ethmoidales ve sphenoidalis. Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, 3:71-78, 1997.
26. Aydınlıoğlu, A., Şakul, U., Anadolu, Y., Diyarbakırlı, S., Keleş, P.: Morphometric evaluation of endoscopic endonasal dacryocystorhinostomy in human male cadavers. The Medicine and Health Journal, 3:9 - 13, 1999.
27. Aka, S., Şakul, B.U. : Kimliği bilinmeyen bir olgunun anatomik yeniden yüzlendirme tekniği ile kimliklendirilmesi. Adli Bilimler Dergisi, Cilt:6, Sayı:1,65-70, 2007.
28. Uzun, M., Şakul, BU.: Genital organların anatomik ve histolojik gelişimi. Türkiye Klin. Jinekoloji Obstetrik Özel Derg., Cilt:3, Sayı:2, 4-8, 2010.

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Adı Soyadı Prof.Dr. Alper ATASEVER
E-Posta aatasever@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Oküler motor sistem, trase izleme

Seçili Yayınları / Tüm Yayınları

Lipid peroxid level increase in experimental hydrocephalus

H. Caner, A. Atasever, K. Kilinc, B. Durgun, S. Peker, O.E. Ozcan

Acta Neurochirurgica 1993; 121: 68-71

Unrotated left kidney associated with an accessory renal artery

A. Atasever, H.H. Çelik, B. Durgun, E. Yılmaz

Journal of Anatomy 1992; 181: 507

The peripheral course of the axons innervating the medial rectus muscle within the subarachnoid portion of the oculomotor nerve

A. Atasever, B. Durgun, T. Kansu, M. Cumhur

Journal of Anatomy 1992; 181: 499-501

Somatotopic organization of the axons innervating the superior rectus muscle in the oculomotor nerve of the rat

A. Atasever, B. Durgun, E. Yilmaz, H.H. Celik

Acta Anatomica 1993; 146: 251-254

Evaluation by angiography of the lateral dominance of the drainage of the dural venous sinuses.

B. Durgun, E.T.Ilgit , M.O. Cizmeli, A. Atasever

Surgical and Radiologic Anatomy 1993; 15: 125-130

Arteria thyroidea ima arising from the brachiocephalic trunk with bilateral absence of inferior thyroid arteries.

E. Yilmaz, H.H. Celik, B. Durgun, A. Atasever, S. Ilgi

Surgical and Radiologic Anatomy 1993; 15: 197-199

Labelling of the neurons in the rat superior cervical ganglion after injection of wheat-germ agglutinin-horseradish peroxidase into the contralateral ganglion: Evidence of transneuronal labelling

A. Atasever, S. Palaoglu, A. Erbengi, H.H. Celik

Journal of Anatomy 1994, 184: 93-97

Morphological assessment in pinealectomy and foetal pineal gland transplantation in rats: Part I

S. Palaoglu, A. Sungur, A. Atasever, S. Ruacan, S. Akalin, T. Ozgen, A. Erbengi

Acta Neurochirurgica 1994, 128: 1-7

Comparison of silk sutures and n-butyl-2-cyanoacrylate on the healing of skin wounds. A pilot study

C.B. Giray, A. Sungur, A. Atasever, K. Araz

Australian Dental Journal 1995; 40(1): 43-45

Clinical and electron microscope comparison of silk sutures and n-butyl-2- cyanoacrylate in human mucosa.

C.B. Giray, A. Atasever, B. Durgun, K. Araz

Australian Dental Journal 1997, 42(4): 255-8

Transient bone loss of distal radius and ulna following clean-cut tendon injuries, repair and passive mobilisation

E Kekilli, K Ertem, C Yagmur, A Atasever, N Elmalı, F Ceylan

Journal of Hand Surgery (European Volume) 2007, 32E: 3: 320-325

Melatonin Prevents Cyclosporine-Induced Hepatotoxicity in Rats

M Kurus, M Esrefoglu, G Sogutlu, A Atasever

Medical Principles and Practice 2009, 18: 407-410

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Adı Soyadı Prof.Dr. Ertuğrul KILIÇ
E-Posta ekilic@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Beyin Felci; Nörobiyoloji

Seçili Yayınları / Tüm Yayınları

1. Elibol-Can B, Kilic E, Yuruker S, Jakubowska-Dogru E. Investigation into the effects of prenatal alcohol exposure on postnatal spine development andexpression of synaptophysin and PSD95 in rat hippocampus. Int J Dev Neurosci. 2014;33:106-14. doi: 10.1016/j.ijdevneu.2013.12.003. Epub 2013 Dec 21.

2. Elibol-Can B, Dursun I, Telkes I, Kilic E, Canan S, Jakubowska-Dogru E. Examination of Age- dependent effects of fetal ethanol exposure on behavior, hippocampal cellcounts, and doublecortin immunoreactivity in rats. Dev Neurobiol. 2013 Oct 29. doi: 10.1002/dneu.22143. [Epub ahead of print]

3. Karadeli HH, Aktekin B, Yilmaz B, Kilic E, Uzar E, Aci A, Bingol CA. Effects of melatonin on behavioral changes of neonatal rats in a model of cortical dysplasia. Eur Rev Med Pharmacol Sci. 2013 ;17(15):2080-4

4. Sehirli AO, Koyun D, Tetik S, Ozsavcı D, Yiğiner O, Cetinel S, Tok OE, Kaya Z, Akkiprik M, Kilic E, Sener G. Melatonin protects against ischemic heart failure in rats. J Pineal Res. (2013) 55(2):138-48

5. Kilic U, Yilmaz B, Reiter RJ, Yüksel A, Kilic E. Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice. Neuroscience. (2013) May 1;237:268-76

6. Kilic U, Kilic E, Tuzcu Z, Tuzcu M, Ozercan IH, Yilmaz O, Sahin F, Sahin K. Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond). (2013) 12;10(1):7

7. Kilic U, Yilmaz B, Ugur M, Yüksel A, Reiter RJ, Hermann DM, Kilic E. Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia (2012) Journal of Pineal Research, 52: 228-35. (I.F.: 5.85)

8. Kelestemur S, Kilic E, Uslu U, Cumbul A, Ugur M, Akman S, Culha M. Wound Healing Properties of Modified Silver Nanoparticles and their Distribution in Mouse Organs after Topical Application. (2012) Nano Biomedicine and Engineering, 4: 170-176.

9. Herz J, Reitmeir R, Hagen SI, Reinboth BS, Guo Z, Zechariah A, Elali A, Doeppner TR, Bacigaluppi M, Pluchino S, Kilic U, Kilic E, Hermann DM.Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. (2012) Neurobiology of Diseases, 45:1077-85 (I.F.: 4.9)

10. Reitmeir R, Kilic E, Reinboth BS, Guo Z, ElAli A, Zechariah A, Kilic U, Hermann DM. Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain.. (2012) Acta Neuropathologica. 123: 273-84 (I.F.: 7.5)

11. Mete F, Kilic E, Somay A, Yilmaz B. Effects of heat stress on endocrine functions & behaviour in the pre-pubertal rat. Indian J Med Res. 2012;135:233-9.

12. Reitmeir R., Kilic E, Kilic U, Bacigaluppi, M, ElAli A, Salani G, Pluchino S, Gassmann M, Hermann DM. Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodeling and contralesional pyramidal tract plasticity. (2011) Brain, 134:84-99 (I.F.: 9.603)

13. Kilic E, Elali A, Kilic U, Guo Z, Ugur M, Uslu U, Bassetti CL, Hermann DM. Role of Nogo-A in neuronal survival in the reperfused ischemic brain (2010) Journal of Cerebral Blood Flow and Metabolism, 30 (5), pp. 969-984. (I.F.: 5.741)

14. Tug, N., Kilic, U., Karateke, A., Yilmaz, B., Ugur, M., Kilic, E. Erythropoietin receptor-like immunostaining on human spermatozoa. (2010) Reproductive BioMedicine Online 21 (5):718-720. (I.F.: 2.380)

15. Yulug B, Erkol G, Kilic E. An interesting link between microgravity and psychiatric diseases. (2010) J Neuropsychiatry Clin Neurosci. 22: 451-g.e12-451.e12. . (I.F.: 2.362)

16. Yulug B, Ozan E, Kilic E. Brain-derived neurotrophic factor polymorphism as a genetic risk for depression? A short review of the literature. (2010) J Neuropsychiatry Clin Neurosci. Winter;22(1):123d.e5-123.e6

17. Muammer R, Kilic E, Hayran O. The effect of physiotherapy treatment on saliva decrease in children with cerebral palsy. Indian Journal of Physiotherapy and Occupational Therapy—An International Journal. (2010) 4: 129-131

18. Sahin K, Akdemir F, Tuzcu M, Sahin N, Onderci M, Ozercan R, Ilhan N, Kilic E, Seren S, Kucuk O. Genistein suppresses spontaneous oviduct tumorigenesis in quail. (2009) Nutr Cancer. 2009 Nov;61(6):799-806. (I.F.: 2.360)

19. Yalvac, M.E., Rizvanov, A.A., Kilic, E., Sahin, F., Mukhamedyarov, M.A., Islamov, R.R., Palotás, A. Potential role of dental stem cells in the cellular therapy of cerebral ischemia (2009) Current Pharmaceutical Design, 15 (33), pp. 3908-3916. (I.F.: 4.399)

20. Yulug B, Kilic E. Olanzapine does not aggrevate ischemic neuronal injury by focal cerebral ischemia: A dose related restriction of the neuroprotective effect? (2009) Medicinal Chemistry, 5 (3), pp. 279-282. (I.F.: 2.362)

21. Bacigaluppi M, Pluchino S, Peruzzotti-Jametti L, Kilic E, Kilic U, Salani G, Brambilla E, West MJ, Comi G, Martino G, Hermann DM. Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms (2009) Brain, 132 (8), pp. 2239-2251. (I.F.: 9.603)

22. Aydin O. Kahraman M. Kilic E. Çulha M. Surface-enhanced raman scattering of rat tissues (2009) Applied Spectroscopy, 63 (6), pp. 662-668. (I.F.: 2.062)

23. Yildirim G, Attar R, Ficicioglu C, Karateke A, Ozkan F, Kilic E, Yilmaz B, Yesildaglar N. Kombine letrozol ve melatonin tedavisinin deneysel rat endometriosis modelinde lezyon boyutları ve histopatolojik skorlar üzerine etkisi J Turkish German Gynecol Assoc. Year: 2009 Volume: 10 Issue: 4 199-204

24. Yulug B, Ozan E, Gönül AS, Kilic E. Brain-derived neurotrophic factor, stress and depression: A minireview (2009) Brain Research Bulletin, 78 (6), pp. 267-269. (I.F.: 2.281) X

25. Hermann DM, Kilic E. Therapeutic potential and possible risks of pleiotropic growth factors in ischemic stroke (2008) Stroke, 39 (11), p. e182. (I.F.: 6.499)

26. Cam E, Yulug B, Cengiz N, Poelkin E, Isik D, Bakar M, Ozan E, Kilic E. Melatonin: A suitable agent for depression associated with stroke? (2008) Journal of Neuropsychiatry and Clinical Neurosciences, 20 (4), pp. 498-500. (I.F.: 2.362)

27. Kilic E, Hermann DM, Spudich A, Kilic Ü, Rentsch KM, Vig R, Matter CM, Bassetti CL. ABCC1: A gateway for pharmacological compounds to the ischaemic brain (2008) Brain, 131 (10), pp. 2679-2689. (I.F.: 9.603)

28. Gao B, Kilic E, Baumann CR, Hermann DM, Bassetti CL. Gamma-hydroxybutyrate accelerates functional recovery after focal cerebral ischemia (2008) Cerebrovascular Diseases, 26 (4), pp. 413-419. (I.F.: 3.041)

29. Kilic E, Kilic U, Bacigaluppi M, Guo Z, Abdallah NB, Wolfer DP, Reiter RJ, Bassetti CL. Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice (2008) Journal of Pineal Research, 45 (2), pp. 142-148. (I.F.: 5.056)

30. Kilic U, Kilic E, Matter CM, Bassetti CL, Hermann DM. TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration (2008) Neurobiology of Disease, 31 (1), pp. 33-40. (I.F.: 4.852)

31. Bacigaluppi M, Pluchino S, Martino G, Kilic E, Hermann DM. Neural stem/precursor cells for the treatment of ischemic stroke (2008) Journal of the Neurological Sciences, 265 (1-2), pp. 73-77. (I.F.: 2.359)

32. Hédou GF, Koshibu K, Farinelli M, Kilic E, Gee CE, Kilic U, Baumgärtel K, Mansuy IM. Protein phosphatase 1-dependent bidirectional synaptic plasticity controls ischemic recovery in the adult brain (2008) Journal of Neuroscience, 28 (1), pp. 154-162. (I.F.: 7.452)

33. Kilic E, Hermann DM, Wippel A, Kilic Ü, Vogel P, Kim M, van der Putten H, Böttiger BW. Poxvirus-derived cytokine response modifier A (CrmA) does not protect against focal cerebral ischemia in mice (2007) Brain Research, 1185 (1), pp. 293-300. (I.F.: 2.494)

34. Yulug B, Cam E, Yildiz A, Kilic E. Buprenorphine does not aggrevate ischemic neuronal injury in experimental focal cerebral ischemia (2007) Journal of Neuropsychiatry and Clinical Neurosciences, 19 (3), pp. 331-334. (I.F.: 2.362)

35. Kilic Ü, Hermann DM, Kilic E, Järve, A, Guo, Z, Spudich, A, Bieber, K, Marti HH. Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways (2006) Journal of Neuroscience, 26 (48), pp. 12439-12446. (I.F.: 7.452)

36. Hermann DM, Kilic E, Spudich A, Krämer SD, Wunderli-Allenspach H, Bassetti CL. Role of drug efflux carriers in the healthy and diseased brain (2006) Annals of Neurology, 60 (5), pp. 489-498. (I.F.: 9.935)

37. Baumann CR, Kilic E, Petit B, Werth E, Hermann DM, Tafti M, Bassetti CL. Sleep EEG changes after middle cerebral artery infarcts in mice: Different effects of striatal and cortical lesions (2006) Sleep, 29 (10), pp. 1339-1344. (I.F.: 4.475)

38. Kilic E, Kilic Ü, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia (2006) FASEB Journal, 20 (8), pp. E307-E314. (I.F.: 7.049)

39. Kilic E, Kilic U, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. (2006) The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (8), pp. 1185-1187. (I.F.: 7.049)

40. Yulug B, Yildiz A, Güzel O, Kilic E, Schäbitz WR, Kilic E. Risperidone attenuates brain damage after focal cerebral ischemia in vivo (2006) Brain Research Bulletin, 69 (6), pp. 656-659. (I.F.:2.281)

41. Spudich A, Kilic E, Xing H, Kilic Ü, Rentsch KM, Wunderli-Allenspach H, Bassetti CL, Hermann DM. Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia (2006) Nature Neuroscience, 9 (4), pp. 487-488. (I.F.: 14.164)

42. Kilic E, Kilic U, Hermann DM. TAT fusion proteins against ischemic stroke: Current status and future perspectives (2006) Frontiers in Bioscience, 11 (2), pp. 1716-1721. (I.F.: 3.308)

43. Kilic E, Kilic Ü, Soliz J, Bassetti CL, Gassmaim M, Hermann DM. Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways (2005) FASEB Journal, 19 (14), pp. 2026-2028. (I.F.: 7.049)

44. Kilic, E, Kilic Ü, Hermann DM. TAT-GDNF in neurodegeneration and ischemic stroke (2005) CNS Drug Reviews, 11 (4), pp. 369-378. (I.F.: 4.432)

45. Kilic E, Kilic Ü, Bähr M, Hermann DM. Tissue plasminogen activator-induced ischemic injury is reversed by NMDA antagonist MK-801 in vivo (2005) Neurodegenerative Diseases, 2 (2), pp. 49-55. (I.F.: 2.989)

46. Spudich A, Frigg R, Kilic E, Kilic U, Oesch B, Raeber A, Bassetti CL, Hermann DM. Aggravation of ischemic brain injury by prion protein deficiency: Role of ERK-1/-2 and STAT-1 (2005) Neurobiology of Disease, 20 (2), pp. 442-449. (I.F.: 4.852)

47. Kilic E, Kilic Ü, Reiter RJ, Bassetti CL, Hermann DM. Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: Role of iNOS and Akt (2005) Journal of Pineal Research, 39 (2), pp. 151-155. (I.F.: 5.056)

48. Kilic Ü, Bassetti CL, Kilic E, Xing H, Wang Z, Hermann DM. Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2 (2005) Neuroscience, 134 (3), pp. 901-906. (I.F.: 3.556)

49. Grimm C, Hermann DM, Bogdanova A, Hotop S, Kilic Ü, Wenzel A, Kilic E, Gassmann M. Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration (2005) Seminars in Cell and Developmental Biology, 16 (4-5), pp. 531-538. (I.F.: 4.528)

50. Reiter RJ, Tan DX, Leon J, Kilic Ü, Kilic E. When melatonin gets on your nerves: Its beneficial actions in experimental models of stroke (2005) Experimental Biology and Medicine, 230 (2), pp. 104-117. (I.F.: 2.202)

51. Kilic Ü, Kilic E, Soliz J, Bassetti CL, Gassmann M, Hermann DM. Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2 (2005) FASEB Journal, 19 (2), pp. 249-251. (I.F.: 7.049)

52. Kilic E, Kilic Ü, Matter CM, Lüscher TF, Bassetti CL, Hermann DM. Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase (2005) Stroke, 36 (2), pp. 332-336. (I.F.: 6.499)

53. Kilic Ü, Kilic E, Reiter RJ, Bassetti CL, Hermann DM. Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice (2005) Journal of Pineal Research, 38 (1), pp. 67-71. (I.F.: 5.056)

54. Wang Y, Kilic E, Kilic Ü, Weber B, Bassetti CL, Marti HH, Hermann DM. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena (2005) Brain, 128 (1), pp. 52-63. (I.F.: 9.603)

55. Kilic E, Kilic Ü, Reiter RJ, Bassetti CL, Hermann DM. Prophylactic use of melatonin protects against focal cerebral ischemia in mice: Role of endothelin converting enzyme-1 (2004) Journal of Pineal Research, 37 (4), pp. 247-251. (I.F.: 5.056)

56. Kilic E, Weishaupt JH, Kilic Ü, Rohde G, Yulug B, Peters K, Hermann DM, Bähr M. The superoxide dismutase1 (SOD1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice (2004) Neuroscience, 128 (2), pp. 359-364. (I.F.: 3.556)

57. Reiter RJ, Kilic Ü, Tan DX, Gitto E, Sainz RM, Mayo JC, Leon J, Kilic E. Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage (2004) Polish Journal of Pharmacology, 56 (2), pp. 159-170. (I.F.: 2.167, The Pharmacological Reports)

58. Kilic Ü, Kilic E, Lingor P, Yulug B, Bähr M. Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro (2004) Acta Neuropathologica, 108 (1), pp. 65-68. (I.F.: 5.310)

59. Kilic Ü, Kilic E, Dietz GPH, Bähr M. The TAT protein transduction domain enhances the neuroprotective effect of glial-cell-line-derived neurotrophic factor after optic nerve transection (2004) Neurodegenerative Diseases, 1 (1), pp. 44-49. (I.F.: 2.989)

60. Kilic E, Kilic Ü, Yulug B, Hermann DM, Reiter RJ. Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator (2004) Journal of Pineal Research, 36 (3), pp. 171-176. (I.F.: 5.056)

61. Kilic E, Kilic Ü, Bassetti CL, Hermann DM. Intravenously administered recombinant tissue-plasminogen activator attenuates neuronal injury after mild focal cerebral ischemia in mice (2004) NeuroReport, 15 (4), pp. 687-689. (I.F.: 1.904)

62. Yulug B, Kilic U, Kilic E, Bähr M. Rifampicin attenuates brain damage in focal ischemia (2004) Brain Research, 996 (1), pp. 76-80. (I.F.: 2.494)

63. Kilic Ü, Kilic E, Dietz GPH, Bähr M. Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice (2003) Stroke, 34 (5), pp. 1304-1310. (I.F.: 6.499)

64. Kügler S, Kilic E, Bähr M. Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area (2003) Gene Therapy, 10 (4), pp. 337-347. (I.F.: 4.492)

65. Kilic E, Hermann DM, Kügler S, Kilic Ü, Holzmüller H, Schmeer C, Bähr M. Adenovirus-mediated Bcl-XL expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice (2002) Neurobiology of Disease, 11 (2), pp. 275-284. (I.F.: 4.852)

66. Kilic E, Dietz GPH, Hermann DM, Bähr M. Intravenous TAT-Bcl-XL is protective after middle cerebral artery occlusion in mice (2002) Annals of Neurology, 52 (5), pp. 617-622. (I.F.: 9.935)

67. Dietz GPH, Kilic E, Bähr M. Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction (2002) Molecular and Cellular Neuroscience, 21(1), pp. 29-37. (I.F.: 3.934)

68. Kilic E, Hermann DM, Isenmann S, Bähr M. Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice (2002) Journal of Pineal Research, 32 (2), pp. 106-111. (I.F.: 5.056)

69. Hermann DM, Kilic E, Kügler S, Isenmann S, Bähr M. Adenovirus-mediated glial cell line-derived neurotrophic factor (GDNF) expression protects against subsequent cortical cold injury in rats (2001) Neurobiology of Disease, 8 (6), pp. 964-973. (I.F.: 4.852)

70. Kilic E, Bähr M, Hermann DM. Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: Role of hemodynamic alterations (2001) Stroke, 32 (11), pp. 2641-2647. (I.F.: 6.499)

71. Dietz GPH, Kilic E, Bähr M, Isenmann S. Bcl-2 is not required in retinal ganglion cells surviving optic nerve axotomy (2001) NeuroReport, 12 (15), pp. 3353-3356. (I.F.: 1.904)

72. Hermann DM, Kilic E, Kügler S, Isenmann S, Bähr M. Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice (2001) Neurobiology of Disease, 8 (4), pp. 655-666. (I.F.: 4.852)

73. Knöll B, Isenmann S, Kilic E, Walkenhorst J, Engel S, Wehinger J, Bähr M, Drescher U. Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve (2001) Mechanisms of Development, 106 (1-2), pp. 119-127. (I.F.: 2.534)

74. Hermann DM, Kilic E, Hata R, Hossmann K-A, Mies G. Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice (2001) Neuroscience, 104 (4), pp. 947-955. (I.F.: 3.556)

75. Sönmez AS, Birincio?lu M, Aydin A, Kiliç E, Şahin N. Effects of misoprostol on the endometrium of ovariectomized rats (2000) Turkish Journal of Medical Sciences, 30(2),pp. 115-118.

76. Kilic E, Hermann DM, Hossmann KA. Recombinant tissue-plasminogen adivator-induced thrombolysis after cerebral thromboembolism in mice (2000) Acta Neuropathologica, 99 (3), pp. 219-222. (I.F.: 5.310)

77. Kilic E, Özdemir YG, Bolay H, Keleştimur H, Dalkara T. Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia (1999) Journal of Cerebral Blood Flow and Metabolism, 19 (5), pp. 511-516. (I.F.: 5.741)

78. Kilic E, Hermann DM, Hossmann KA. Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice
(1999) NeuroReport, 10 (1), pp. 107-111. (I.F.: 1.904)

79. Kilic E, Hermann DM, Hossmann KA. A reproducible model of thromboembolic stroke in mice (1998) NeuroReport, 9 (13), pp. 2967-2970. (I.F.: 1.904)








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Adı Soyadı Prof.Dr. Süleyman YILDIRIM
E-Posta suleymanyildirim@medipol.edu.tr
Detay Öz Geçmiş
Medya

Hacettepe Üniversitesi 1994 Mikrobiyal Genomik Bilimler/Gıda Mikrobiyolojisi/North Carolina State Unıversity

Daha Önce Görev Yaptığı Yerler

-Misafir Bilim İnsanı - J. Craig Venter Institute, Rockville, MD, USA -Baş uzman araştırmacı - Walter Reed Army Institute of Research, Silver Spring, MD, USA -Doktora sonrası araştırmacı- University of Illinois, Urbana, USA -Doktora sonrası araştırmacı- Yale University School of Medicine, New Haven, CT, USA -Doktora (araştırma asistanı)- NC State University, Raleigh, NC, USA -Yüksek Lisans (araştırma asistanı) – Iowa State University, Ames, IA, USA

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

Yildirim, S., Yeoman, CJ., Chandra, SJ., Thomas, SM., Ho, M., Leigh, SR., White, BA., Wilson, BA., and Stumpf, RM. 2014. Primate vaginal microbiota exhibit species specificity without phylogenetic congruence or universal Lactobacillus dominance (ISME J. 2014 Jul 18. doi: 10.1038/ismej.2014.90. [Epub ahead of print]).

Stumpf RM, Wilson BA, Rivera A, Yildirim S, Yeoman CJ, Polk JD, White BA, Leigh SR. 2013. The primate vaginal microbiome: comparative context and implications for human health and disease. Am J Phys Anthropol. 57:119-34
Thompson, MG, Black, CC, Pavlicek, RL, Honnold, CL, Wise, MC, Alamneh, YA, Williams, R, Kirkup, BC, Yildirim, S, Si, Y, Green, RK, Kessler, JL, Moon, JK, Palys, TJ, Zurawski, DV. 2013. Validation of a Novel Murine Wound Model of Acinetobacter baumannii Infection. Antimicrob. Agents Chemother. Antomicrob. Agents Chemotherap. 58:1332-42

Amato KR, Yeoman CJ, Kent A, Righini N, Carbonero F, Estrada A, Gaskins HR, Stumpf RM, Yildirim S, Torralba M, Gillis M, Wilson BA, Nelson KE, White BA and Leigh SR*. 2013. Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes. J. ISME. 7:1344-53

Broadway M, Rogers E, Chang C., Huang I, Dwivedi P, Yildirim S, Schmitt S, Das A., and Ton-That H*. 2013. Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode. J. Bacteriology. 195:3774-83
Ratani SS, Siletzky RM, Dutta V, Yildirim S, Osborne JA, Lin W, Hitchins AD, Ward TJ, Kathariou S*. 2012. Heavy metal and disinfectant resistance of Listeria monocytogenes from foods and food processing plants. Appl Environ Microbiol. 78:6938-45

Yildirim, S. (2012). Terrestrial Vertebrate Animal Metagenomics, Non-domesticated Primates: Prosimians. In, Encyclopedia of Metagenomics, Animals. Ed. Karen E Nelson (Editor in Chief), Bryan A. White, Sarah Highlander, Francisco Rodriguez-Valera (Volume editors). Springer.

Yeoman CJ, Chia N., Yildirim S., Miller MEB., Kent A., Stumpf R., Leigh S.R., Nelson KE., White BA*., Wilson BA. 2011. Towards an Evolutionary Model of Animal-Associated Microbiomes. J. Entropy. 13:570-594.

Yildirim S, Yeoman, CJ., Sipos, M., Wilson, BA., Goldberg, TL., Stumpf, R, Leigh, SL., White, BA*, and Nelson, KE. 2010. Characterization of the Fecal Microbiome from Non-Human Wild Primates Reveals Species Specific Microbial Communities. PLoS ONE 5: e13963.
Yeoman CJ, Yildirim S, Thomas SM, Durkin AS, Torralba M, Sutton, G., Buhay, CJ., Ding, Y., Dugan-Rocha, SP., Muzny,DM., Qin, X., Gibbs, RA., Leigh, SR.,

Stumpf, R., White, BA., Highlander, SK., Nelson, JE., and Wilson, BA*. 2010. Comparative Genomics of Gardnerella vaginalis Strains Reveals Substantial Differences in Metabolic and Virulence Potential. PLoS ONE 5: e12411
Yildirim S., ElHanefi, D., Lin W, Hitchins AD, RM, Siletzky, and Kathariou, S*. 2010. Conserved genomic localization and sequence content of Sau3AI-like restriction-modification gene cassettes between Listeria monocytogenes Epidemic Clone I and selected strains of serotype 1/2a. Appl. Envir. Microb, 76:5577

Attardo, GM, Lohs, C., Alam, UH., Yildirim, S., and Aksoy, S*. 2008. Analysis of milk gland structure and function in Glossina morsitans: Milk protein production, symbiont populations and fecundity. J Insect Physiol. 54:1236-42
Yildirim S., Lin W, Hitchins AD, Jaykus LA, Altermann E, Klaenhammer TR, Kathariou S*. 2004. Epidemic clone-I specific genetic markers in strains of Listeria monocytogenes serotype 4b from foods. Appl Env. Microbiology. 70:4158-64

Johnson J, Jinneman K, Stelma G, Smith BG, Lye D, Messer J, Ulaszek J, Evsen L, Gendel S, Bennett RW, Swaminathan B, Pruckler J, Steigerwalt A, Kathariou S, Yildirim S, Volokhov D, Rasooly A, Chizhikov V, Wiedmann M, Fortes E, Duvall RE, Hitchins AD*. 2004. Natural atypical Listeria innocua strains with Listeria monocytogenes pathogenicity island-I genes. Appl Env. Microbiol. 70:4256-66
Yildirim S, Fuentes RG, Evangelista R, and Nikolov ZL*. 2002. Fractionation of Transgenic Corn for Optimal Recovery of Recombinant Enzymes. JAOCS. 79:809-814

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Adı Soyadı Prof.Dr. Cafer MARANGOZ
E-Posta cmarangoz@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Doç.Dr. İlknur KESKİN
E-Posta ilknurkeskin@medipol.edu.tr
Detay Öz Geçmiş
Medya

Samsun Ondokuz Mayıs Üniversitesi 1999 Selçuk Üniversitesi

Daha Önce Görev Yaptığı Yerler

Samsun 14 nolu MSO Selçuk Üniversitesi

Araştırma Alanları

Hücre kültürü, axolotl, rejenerasyon, stereoloji, periferik sinir, deri, yara iyileşmesi, beyin travması, üreme biyolojisi, histoloji eğitimi

Seçili Yayınları / Tüm Yayınları

Uluslararası hakemli dergilerde yayımlanan makaleler :
A.1 AYDIN KERAMETTIN,ÇOKLUK CENGIZ,AYAS BÜLENT,ÖNGER MEHMET EMIN,KESKIN ILKNUR,ÖZYASAR ALI FARUK,ASLAN HÜSEYIN,KAPLAN SÜLEYMAN (2011). Hippocampal cell loss
after an anterior and posterior anastomotic vein occlusion model in rats. International Journal of Developmental Neuroscience, 29(7), 717-722., Doi: 10.1016/j.ijdevneu.2011.05.013,
A.2 KESKIN ILKNUR,KAPLAN SÜLEYMAN,KALKAN SABIHA SERPIL,SÜTÇÜ MUSTAFA,ULKAY MUZAFFER BASAK,ESENER OSMAN BEHZAT BURAK (2015). Evaluation of neuroprotection by melatonin
against adverse effects of prenatal exposure to a nonsteroidal anti-inflammatory drug during peripheral nerve development. International Journal of Developmental Neuroscience, 41(41), 1-7., Doi: 10.1016/j.ijdevneu.2014.12.002,
A.3 ÜSTÜNDAG ÜNSAL VELI,SAHIN SADIK,AK KORAY,KESKIN ILKNUR,ALTURFAN EBRU ISIK (2015). The effects of tacrolimus on the activity and expression of tissue factor in the rat ovary with ischemia–reperfusion induced injury. Reproductive Biology, 15(3), 139-145., Doi: 10.1016/j.repbio.2015.07.002,
A.4 DEMIRCAN TURAN,ILHAN AYSE ELIF,AYTÜRK NILÜFER,YILDIRIM BERNA,ÖZTÜRK GÜRKAN,KESKIN ILKNUR (2016). A histological atlas of the tissues and organs of neotenic and metamorphosed
axolotl. Acta Histochemica, 118(7), 746-759., Doi: 10.1016/j.acthis.2016.07.006,
A.5 KESKIN ILKNUR,AYTÜRK NILÜFER,SÜTÇÜ MUSTAFA,KESKIN MUSTAFA,MÜDOK TANGÜL (2017). The use of platelet-rich plasma for storage of surplus harvested skin grafts. Plastic Surgery, 24(4), 1-8., Doi: 10.1177/2292550317693819,
A.6 KESKIN ILKNUR,SÜTÇÜ MUSTAFA,EREN HILAL,KESKIN MUSTAFA (2017). Exposure to Tumescent Solution Significantly Increases Phosphorylation of Perilipin in Adipocytes. Aesthetic Surgery Journal, 37(2), 239-245., Doi: 10.1093/asj/sjw156,
A.7 KESKIN ILKNUR,GÜNAL MEHMET YALÇIN,AYLA SULE,KOLBASI BIRCAN,SAKUL AYSE ARZU,KILIÇ ÜLKAN,GÖK ÖZLEM,ÖZBEK HANEFI (2017). Effects of Foeniculum vulgare essential oil compounds,
fenchone and limonene, on experimental wound healing. Biotechnic & Histochemistry , 1-9., Doi: 10.1080/10520295.2017.1306882,
A.8 ÖZBEK HANEFI,Bahadır Acıkara Özlem,KESKIN ILKNUR,Kirmizi Neriman Ipek,Ozbilgin Serkan,ERGENE ÖZ BURÇIN,KURTUL EKIN,Ozrenk Bade Cevriye,TEKIN MEHMET,SALTAN HAYRIYE
GÜLÇIN (2017). Evaluation of hepatoprotective and antidiabetic activity of Alchemilla mollis. Biomedicine & Pharmacotherapy, 86, 172-176., Doi: 10.1016/j.biopha.2016.12.005,
A.9 DEMIRCAN TURAN,KESKIN ILKNUR,DUMLU SEDA NILGÜN,AYTÜRK NILÜFER,AVSAROGLU MAHMUT ERHAN,akgün emel,ÖZTÜRK GÜRKAN,BAYKAL AHMET TARIK (2017). Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database. PROTEOMICS, 17(1-2), 1-5., Doi: 10.1002/pmic.201600338,
A.10 KESKIN ILKNUR,YILDIRIM BERNA,KOLBASI BIRCAN,ÖZTÜRK GÜRKAN,DEMIRCAN TURAN (2017). A Comparative Study of Fixatives for Axolotl Blastema Tissue. International Journal of Morphology, 35(1), 47-51., Doi: 10.4067/S0717-95022017000100009 ,
A.11 KARABULUT SEDA,KESKIN ILKNUR,Sagıroglu Yusuf Relationship between semen parameters in samples obtained from subfertile patients. Andrology-Open Access
A.12 KESKIN ILKNUR,GÜNAL MEHMET YALÇIN,AYTÜRK NILÜFER,KILIÇ ÜLKAN,OZANSOY MEHMET,KILIÇ ERTUGRUL Dose dependent neuroprotective effect of enoxaparın after cold induced traumatIc
braIn Injury. Neural Regeneration Research
A.13 ÖZBEK HANEFI,BAHADIR ACIKARA ÖZLEM,KESKIN ILKNUR,KIRMIZI NERIMAN IPEK,YIGITBASI TÜRKAN,SAKUL AYSE ARZU,SALTAN HAYRIYE GÜLÇIN Evaluation of Scorzonera sp. Root Extracts
and Major Compounds against Acute Hepatotoxicity Induced by Carbon Tetrachloride. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 79(4)
Uluslararası bilimsel toplantılarda sunulan ve bildiri kitaplarında (proceedings) basılan bildiriler :
B.1 SÜTÇÜ MUSTAFA,KESKIN ILKNUR,AKDAG OSMAN,KESKIN MUSTAFA,TOSUN ZEKERIYA,SAVACI NEDIM (2011). The Investigation of Repair Time and The Effect of Melatonine in Healing of Repaired Peripheral Nerve Injury. Plastic Surgery Special Joint Meeting, 263-264.
B.2 KESKIN ILKNUR,KAPLAN SÜLEYMAN,KALKAN SABIHA SERPIL,SÜTÇÜ MUSTAFA,ULKAY MUZAFFER BASAK,ESENER OSMAN BEHZAT BURAK (2012). An Evaluation of Neuroprotective Effects of
Melatonin Against Adverse Effects of Prenatal Exposure to a Non steroidal Anti Inflammatory Drug During The Peripheral Nerve Development. Asian and African Stereology Congress, 416 (Özet bildiri),
B.3 ALTURFAN EBRU ISIK,KESKIN ILKNUR,SÜTÇÜ MUSTAFA,YIGITBASI TÜRKAN,EMEKLI NESLIN (2014). Tissue Factor expression of adipose tissue in obesity. Fourth International Meeting on
Pharmacy &Pharmaceutical Sciences
B.4 KESKIN ILKNUR,AYTÜRK NILÜFER,SÜTÇÜ MUSTAFA,KESKIN MUSTAFA (2015). The Use of Platelet- Rich -Plasma for Storage of Surplus Harvested Skin Grafts. 12. Multional Congress on
MICROSCOPY, 313-316.
B.5 MÜDOK TANGÜL,KESKIN ILKNUR (2015). Geleneksel Mikroskop Egitiminden Dijital Mikroskop Egitimine Geçis Histoloji Egitiminde Globallesmenin Anahtarı mıdır?. Uluslararası Egitim Bilimleri ve Tıp Egitimi Sempozyumu (Özet bildiri),
B.6 ÖZBEK HANEFI,BAHADIR ACIKARA ÖZLEM,KESKIN ILKNUR,KIRMIZI NERIMAN IPEK,SAKUL AYSE ARZU,YIGITBASI TÜRKAN,SALTAN HAYRIYE GÜLÇIN (2016). Hepatoprotective Effects of Scorzonera L. Species on Carbon Tetrachloride-induced Liver Toxicity in Rats. 7. European Congress of Pharmacology, 566
B.7 KESKIN ILKNUR,DEMIRCAN TURAN,YILDIRIM BERNA,KOLBASI BIRCAN,ÖZTÜRK GÜRKAN (2016). A comparative study of fixatives for axolotl blastema tissue. 1. International Mediterranean Science and Engineering Congress, 3705 (Özet bildiri)
B.8 KESKIN ILKNUR,BEDRI NEJDA,MÜDOK TANGÜL (2016). Histoloji ve Embriyoloji Anabilim Dalında Yapılan Tezlerin Genel Profili. International Conference on Quality in Higher Education, 404-405. (Özet bildiri),
C. Ulusal hakemli dergilerde yayımlanan makaleler :
C.1 EKICI FATIH,KESKIN ILKNUR,ASLAN HÜSEYIN,ERISGIN ZÜLEYHA,ALTUNKAYNAK BERRIN ZÜHAL,GÖKÇIMEN ALPASLAN,ODACI ERSAN,KAPLAN SÜLEYMAN (2012). Does prenatal exposure to diclofenac sodium affect the total number of cerebellar granule cells in male juvenile and adult rats?. Journal of Experimental and Clinical Medicine, 29(1), 52-57., Doi: 10.5835/jecm.omu.29.01.013,
C.2 KESKIN ILKNUR,ÖZBEK HANEFI,AYTÜRK NILÜFER,MÜDOK TANGÜL (2015). Geleneksel Mikroskop Egitiminden Dijital Mikroskop Egitimine Geçis. Tıp Egitimi Dünyası, 14(42), 27-32.,
C.3 KESKIN ILKNUR,DEMIRCAN TURAN,BEDRI NEJDA,KÖROGLU NADIYE (2016). Fare Östrus Siklusu'nun Farklı Fazlarında PLIN2 ve PLIN3 Ekspresyonu. Haydarpasa Numune Egitim ve Arastırma Hastanesi Tıp Dergisi, 56(3), 131-142.,
C.4 DELILBASI BARIS ÇAGRI,AYTÜRK NILÜFER,AYDIN KADER,AKKOYUNLU MURAT,KESKIN ILKNUR (2016). Lateral Sinus Ogmentasyonunda Allojen Kemik Grefti ve Lökosit ve Plateletten Zengin
Fibrin (L-PRF) Kullanımının Mikroskobik ve Radyolojik Olarak Incelenmesi. Turkiye Klinikleri Journal of Oral and Maxillofacial Surgery-Special Topics, 2(3), 33-39.,
C.5 KESKIN ILKNUR,BEDRI NEJDA (2016). Yüksek Fruktoz Içerikli Beslenmenin Overlerde Perilipin Ekspresyonu ve Polikistik Over Gelisimi Ile Iliskisi. Zeynep Kamil Tıp Bülteni, 47(4), 106-110., Doi: 10.16948/zktipb.257211,
C.6 KESKIN ILKNUR,MÜDOK TANGÜL (2016). Kimerizm. Ibni Sina Tıp Bilimleri Dergisi, 2(1), 1-6.,
C.7 KESKIN ILKNUR (2017). accreditted by. Saglık Düsüncesi ve Tıp Kültürü Dergisi(27), 88-93.,
C.8 DEMIRCAN TURAN,KESKIN ILKNUR,GÜNAL MEHMET YALÇIN,ILHAN AYSE ELIF,KOLBASI BIRCAN,ÖZTÜRK GÜRKAN Axolotl cells and tissues enhances cutaneous wound healing in mice.
Journal of Experimental and Clinical Medicine, 33(4), Doi: 10.5835/jecm.omu.33.04.010,
C.9 AYLA SULE,KESKIN ILKNUR,Varlı Yelke Tuba,ÖNEL TUGÇE,KARAHÜSEYINOGLU SERÇIN ErkekInfertilitesinde Seminal Leptin Seviyelerinin Semen Parametreleri ve DNA Fragmantasyonu Ile Iliskisi. ZEYNEP KAMIL TIP BÜLTENI, 48(2), Doi: 10.16948/zktipb.288940,
C.10 KESKIN ILKNUR,KARABULUT SEDA Effects of density gradient sperm preparation on semen parameters and acrosomal status. Haydarpasa Numune Egitim ve Arastırma Hastanesi Tıp Dergisi, 57(2)
C.11 KESKIN ILKNUR,KOLBASI BIRCAN,AKHAN ASLI,ÇELIK HASAN,HANCI MUSTAFA,KESKIN MUSTAFA Hipermastinin eslik ettigi Bilateral Elastofibroma Dorsi Olgusu: Olası bir Iliskinin Sorgulanması. Türk Plastik Rekonstrüktif ve Estetik Cerrahi Dergisi

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Adı Soyadı Doç.Dr. Esra ÇAĞAVİ
E-Posta ecagavi@medipol.edu.tr
Detay Öz Geçmiş
Medya

Boğaziçi Üniversitesi 2002 Kalifornia Üniversitesi Los Angeles Kampüsü

Daha Önce Görev Yaptığı Yerler

Gebze Yüksek Teknoloji Enstitüsü

Araştırma Alanları

Araştırmalarımda genel ilgi alanım: embriyonik ve indüklenmiş kök hücre sistemi kullanarak kalp-damar gelişimi ve hastalıklarının moleküler temellerinin araştırması ve tedavi yöntemleri geliştirilmesidir. Özel alt başlıklar ise: • Embriyonik kök hücrelerden kalp kök hücresi ve kardiyomiyosit elde edilmesi • Kalp kök hücrelerinin farklılaşma ve kendini yenilemesinde gerekli sinyal ileti mekanizmalarının tanımlanması • Kalp ve damar hastalıkları tedavisinde kullanılmak üzere yeni kalp doku mühendisliği uygulamalarının geliştirilmesi • Hastaların deri dokusundan uyarılmış pluripotent kök hücre elde edilmesi ve in vitro modelleme yapılarak hastalık mekanizmasının araştırılmasıdır.

Seçili Yayınları / Tüm Yayınları

1) Cagavi E., Bartulos O., Suh C. Y., Sun B., Yue Z., Jiang Z., Yue L., Qyang Y. “Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation” Plos One (2014). DOI: 10.1371/journal.pone.0110752.

2) Dunworth W. P., Cardona-Costa J., Cagavi E., Kim J. D., Meadows S., Fisher J. C., Wang Y., Cleaver O., Qyang Y., Ober E. A., and Jin S. W. “Bone Morphogenetic Protein 2 Signaling Negatively Modulates Lymphatic Development in Vertebrate Embryos” Circ Res 114 (1) :56-66 (2014).

3) Ge X., Ren Y., Bartulos O., Lee M. Y., Yue Z, Kim K. Y., Li W., Amos P. J., Cagavi Bozkulak E., Iyer A., Zheng W., Zhao H., Martin K. A., Kotton D. N., Tellides G., Park I. H., Yue L., Qyang Y. “Modeling Supravalvular Aortic Stenosis Syndrome Using Human Induced Pluripotent Stem Cells” Circulation 126(14):1695-704 (2012).

4) Alcon A., Cagavi Bozkulak E., Qyang Y. “Regenerating Functional Heart Tissue for Myocardial Repair” Cell Mol Life Sci 69(16):2635-56 (2012).

5) Amos P. J., Cagavi Bozkulak E., Qyang Y. “Methods of Cell Purification: A Critical Juncture for Laboratory Research and Translational Science” Cells Tissues Organs 195(1-2):26-40 (2012).

6) Lee M. Y., Cagavi Bozkulak E., Schliffke S., Amos P. J., Ren Y., Ge X., Ehrlich B. E., Qyang Y. “High Density Cultures of Embryoid Bodies Enhanced Cardiac Differentiation of Murine Embryonic Stem Cells” Biochem Biophys Res Commun 416, 51-57 (2011).

7) Lee M. Y., Sun B., Schliffke S., Yue Z., Ye M., Paavola J, Cagavi Bozkulak E., Amos P.J., Ren Y., Ju R., Jung Y. W., Ge X., Yue L., Ehrlich B. E., Qyang Y. “Derivation of Functional Ventricular Cardiomyocytes Using Endogenous Promoter Sequence from Murine Embryonic Stem Cells” Stem Cell Res 8, 49–57 (2011).

8) Bozkulak E. C., Weinmaster G. “Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling” Mol Cell Bio 29(21), 5679–5695 (2009).

9) Rooke N., Vadim M., Cagavi E., Black D. L. “Roles for SR Proteins and hnRNP A1 in the Regulation of c-src Exon N1” Mol Cell Bio 23(6), 1874-1884 (2003).

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Adı Soyadı Doç.Dr. Mustafa GÜZEL
E-Posta mguzel@medipol.edu.tr
Detay Öz Geçmiş
Medya

Hacettepe Üniversitesi 1987 Clemson Üniversitesi Mühendislik ve Doğal Bilimler Fakültesi Medisinal Kimya Anabilim Dalı

Daha Önce Görev Yaptığı Yerler

MEB (Kimya Öğretmenliği, 1988-1993, İzmir Yüksek Teknoloji Enstitüsü (Araştırma Görevlisi (1993-2000), Clemson Üniversitesi (Öğretim Görevlisi 1997-1998), Northeastern Üniversitesi (Misafir Araştırma Görevlisi ve Organik Kimya Lab. Koordinatörü, 1998-2000), ArQule Inc. (Senyör. Sentetik Organik Kimyacı, 2000), TransTech Pharma Inc. (Proje sorumlusu, uzman bilim insanı, medisinal kimya lab. direktörü, 2001-2014).

Araştırma Alanları

• Yenilikçi ilaç Ar-Ge çalışmaları, ilaç keşif ve geliştirme özellikle kanser, kinaz inhibitörleri, Tip-2 şeker hastalığının tedavisi için G Proteinle Çiftleşmiş Reseptörlerinin incelenmesi, obezlik, merkezi sinir sistemi hastalıkları (Alzheimer ve Parkinson gibi), römatoit artiritis gibi inflammasyonla ilgili ilaç geliştirilmesi. • Yeni ilaç moleküllerini geliştirmek üzere simetrik veya asimetrik moleküllerin dizayni ve senteziyle ilgili Ar-Ge çalişmaları. Doğal bileşiklerin aktif maddelerinin izolasyon, sentezleme metodları ve teknikleri. • Katalitik asimetrik indüksiyon reaksiyonlarının mekanizmalarının incelenmesi ve bunlardan çıkarak biyoljik sistemlerde aktif olabilecek ilaçlarin geliştirilip sentezleme yöntemleri.

Seçili Yayınları / Tüm Yayınları

1. "Gender Satisfaction among Type 2 Diabetes Patients: A Comparison between Intensive Diets, Lifestyle Intervention with Medication Controlled Management"; Abdulbari Bener, Abdulla O. A. A. Al-Hamaq, Funda Çatan, Kaleem U. Rajput and Mustafa Guzel; British Journal of Medicine & Medical Research, volume: 18, number: 7, page:1-13, 2016. DOI: 10.9734/BJMMR/2016/29418.
2. "Medisinal Kimyanın Yeni İlaç Keşif ve Geliştirmedeki Rolü ve Önemi:The Role and Importance of Medicinal Chemistry in Novel Drug Discovery and Development"; Mustafa Güzel, ve Sezgin Kiren; Turkish Clinics, Turkiye Klinikleri J Pharm Sci 2016;5(1):36-45, 2016. DOI: 10.5336/pharmsci.2015-48211.
3. "Synthesis of Substituted Pyridines from 1,2-Nucleophilic Addition Products of Functionalized N-Acyl-2,3-dihydropyridones"; Mustafa Guzel, Joshua Watts, Matthew McGilvary, Marcus Wright, and Sezgin Kiren; Tetrahedron Letters, volume: 56, number: 38, (2015), p:5872. doi:10.1016/j.tetlet.2015.07.045.
4. “Estimation of Octanol-Water Partition Coefficient Using Cationic Gemini Surfactants by Micellar Electrokinetic Chromatography’; Mustafa Guzel, Cevdet Akbay, Yatzka Hoyos , David H. Ahlstrom; Journal of Chromatography and Separation Techniques, volume: 6, number: 4, (2015), p-. doi:10.4172/2157- 7064.1000275.
5. "Induction of Heme Oxygenase I (HMOX1) by HPP-4382: A novel modulator of Bach-1 activity”; Otis Attucks, Kimberly Jasmer, Mark Hannink, Jareer Kassis, Zhenping Zhong, Suparna Gupta, Sam Victory, Mustafa Guzel, Dharma Polisetti, Robert Andrews, Adnan Mjalli, and Matthew Kostura; PLoSOne, 9, 7, (2014), p:1-12, e101044.
6. "Substituted Pyran Derivatives Useful as Antitumor Agents"; Mustafa Guzel, Devi Reddy, Rongyuan Xie, Dharma R. Polisetti, Stephen Davis, Soumya Sahoo, Hassan El Abdelloui, and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent #US 61/892,053, 2013.
7. "Substituted Fused Oxazoline Derivatives Useful as Antitumor Agents"; Mustafa Guzel, Devi Reddy, Rongyuan Xie, Dharma R. Polisetti, Soumya Sahoo, Stephen Davis, Mohan Rao, Kalpathy Santhosh, and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent #US 61/892,018, 2013.
8. "Characterization and application of molecular binary mixed molecular micelles of sodium10-undecenyl sulfate and sodium N-undecenyl leucinate as pseudostationary phases in micellar electrokinetic chromatography"; Cevdet Akbay, Hamid H. Ahmed, Hakan Arslan, Brittany Graham, and Mustafa Guzel; Talanta, 99, (2012), 441-449.
9. " Study of chemical selectivity of binary mixed micelles of sodium 10-undecenyl sulfate and sodium N-undecenyl leucinate using linear solvation energy reletionships model"; Hamid H. Ahmed, David M. Ahlstrom, Hakan Arslan, Mustafa Guzel, and Cevdet Akbay; Journal of Chromatography A, 1236, (2012), 207-214.
10. “Novel Anticancer agents for hexokinase inhibition-Substituted cyclic-3-indole derivatives”; Mustafa Guzel, Rongyuan Xie, Dharma R. Polisetti, Robert C. Andrews, Adnan M. M. Mjalli, and Stephen Davis; High Point Pharmaceuticals Inc., High Point, NC, Application No: HPP 3018.001 US; patent manuscript submitted, 2013.
11. “Substituted Benzimidazole Derivatives and Methods of Use to Treat Oxidative Stress”; Mustafa Guzel, Sam Victory, Dharma R. Polisetti, Mathew Kostura, Adnan M. M. Mjalli, Otis Attucks, and Jareer Kassis; High Point Pharmaceuticals Inc., High Point, NC, Application No: HPP 3007.000 US; patent manuscript submitted, 2012.
12. “Substituted Pyridine derivatives, Pharmaceutical Compositions, and Methods of Use to Treat Oxidative Stress”; Mustafa Guzel, Sam Victory, Bapu Gaddam, Dharma R. Polisetti, Mathew Kostura and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent # WO 2011/022216, (02, 24, 2011).
13. “Oxadiazoanthracene Compounds, for Treatments of Diabetes”; Scott T. Yokum, Mustafa Guzel, Kalpathy C. Santhosh, Dharma R. Polisetti, Daniel P. Christen, Adnan M. Mjalli, and Stephen T. Davis; TransTech Pharma Inc., High Point, NC, , Patent # US 2011/7906507 (03, 15, 2011).
14. “In Silico Ligand-Receptor Docking of Potentially Selective Butyrylcholinesterase Inhibitors Structurally Related to the Marine Natural Product Debromoflustramine B”; Miguel O. Mitchell, Robert W. Figliozzi and Mustafa Guzel; Medicinal Chemistry, Volume 6, Number 3, 2010, Pp. 141-143.
15. “Substituted Pyridine derivatives, Pharmaceutical Compositions, and Methods of Use to Treat Oxidative Stress”; Mustafa Guzel, Sam Victory, Bapu Gaddam, Dharma R. Polisetti, Mathew Kostura and Adnan M. M. Mjalli; High Point Pharmaceuticals Inc., High Point, NC, Patent # US 2010/044508, (05, 08, 2010).
16. “Mandelic Acid Derivatives and Preparation Thereof”; Mustafa Guzel, Scott T. Yokum, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # US 2010/0036150, (02,11, 2010).
17. “Oxadiazoanthracene Compounds, Compositions of Oxadiazoanthracene Compounds and Methods of Treatment Using the Same”; Scott T. Yokum, Mustafa Guzel, Kalpathy C. Santhosh, Dharma R. Polisetti, Daniel P. Christen, Adnan M. Mjalli, and Stephen T. Davis; TransTech Pharma Inc., High Point, NC, , Patent # US 2010/0324033 (12, 23, 2010).
18. “Substituted Azoanthracene Derivatives, Pharmaceutical Compositions, and Methods of Use Thereof”; Mustafa Guzel, Scott T. Yokum, Kalpathy C. Santhosh, Dharma R. Polisetti, Chris Behme, Adnan M. Mjalli, and Stephen T. Davis”; TransTech Pharma Inc., High Point, NC, Patent # WO 2010/4824 (07, 10, 2010).
19. “Tricyclic Compounds as Modulators of TNF-? Synthesis”; Mustafa Guzel, Mathew Kostura, Adnan M. Mjalli, Bapu Gaddam, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # US 2010/0190808 (07, 29, 2010).
20. “Oxadiazoanthracene Compounds, for Treatments of Diabetes”; Scott T. Yokum, Mustafa Guzel, Kalpathy C. Santhosh, Dharma R. Polisetti, Daniel P. Christen, Adnan M. Mjalli, and Stephen T. Davis; TransTech Pharma Inc., High Point, NC, , Patent # WO 2009/111700 (11, 09, 2009).
21. “Aryl Carbonyl Derivatives as Therapeutic Agents-Part-II”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2009/7541373 (06, 02, 2009).
22. “Tricyclic Compounds as Modulators of TNF-? Synthesis as PDE4 Inhibitors”; Mustafa Guzel, Mathew Kostura, Adnan M. Mjalli, Bapu Gaddam, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # WO 2009/094528, (07, 30, 2009).
23. “Aryl, and Hetoroaryl Compounds, Compositions, and Methods of Use”; Mustafa Guzel, Murty Arimilli, Muralidhar Bundlela, Elizabeth Guo, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2008/7459472 (12, 02, 2008).
24. “Aryl Carbonyl Derivatives as Therapeutic Agents-Part-I”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2008/7384967 (06, 10, 2008).
25. “Mandelic Acid Derivatives and Preparation Thereof”; Mustafa Guzel, Scott T. Yokum, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC, Patent # WO 2008/051563, (05, 02, 2008).
26. “Exploiting ?-Shielding Interactions of ?6 Arene Chromium (0) Complexes: New Auxiliaries derived from the Biogenic Chiral Pool”; Jane Li, Longfei Xie, Mustafa Guzel, Steven B. Heaton, Dong Ma, Amy E. Kallmerten, and Graham B. Jones; Journal of Organometallic Chem., 2007,. 692, 5459-5473.
27. “Aryl, and Hetoroaryl Compounds, Compositions, and Methods of Use”; Mustafa Guzel, Murty Arimilli, Muraldhar Bundlela, Elizabeth Guo, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2005/0059713 (03, 17, 2005).
28. “Novel Aryl Compounds for Antiviral Activity: Amide Derivatives as Therapeutic Agents”; Mustafa Guzel, Murty Arimilli, Muraldhar Bundle, Elizabeth Guo, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # WO 2005/014534 (02, 17, 2005).
29. “Aryl Carbonyl Derivatives as Therapeutic Agents”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2004/0122235 (06, 24, 2004).
30. “Aryl Carbonyl Derivatives as Therapeutic Agents”; Kalpaty C. Santhosh, Mustafa Guzel, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # WO 2004/002481 (01, 08, 2004).
31. “Novel GlucoKinase Activators: Amide Derivatives as Therapeutic Agents-Part-II”; Mustafa Guzel, Kalpaty C. Santhosh, Dharma R. Polisetti, Adnan M. Mjalli, and Robert C. Andrews; TransTech Pharma Inc., High Point, NC, Patent # US 2003/0171411 (09,11, 2003).
32. “Novel GlucoKinase Activators: Amide Derivatives as Therapeutic Agents-Part-I”; Mustafa Guzel, Kalpaty C. Santhosh, Adnan M. Mjalli, Robert C. Andrews, and Dharma R. Polisetti; TransTech Pharma Inc., High Point, NC; Patent # WO 03/055482 (07, 10, 2003).
33. “Enantioselective Catalysis Using Planar Chiral ?6 Arene Chromium Complexes: 1,2-Diols as Cycloaddition Catalysts”; Graham B. Jones, Mustafa Guzel and Steven B. Heaton; Tetrahedron: Asymmetry, 2000, 11, 4303-4320.
34. “Exploiting ?-Shielding Interactions in a ?6 Arene Complexes Chiral Auxiliary”; Graham B. Jones, and Mustafa Guzel; Tetrahedron Letters, 2000, 41, 4695-4699.
35. “Catalytic Enantioselective Cycloaddtions: A readily Available Diels-Alder Catalyst”; Graham B. Jones, and Mustafa Guzel; Tetrahedron: Asymmetry, 2000, 11, 1267-1271.
36. “Stereoselective Route to Mitosenes via Tricarbonyl ?6 Arene Chromium (0) Complexes”; Graham B. Jones, Mustafa Guzel, and Jude E. Mathews; Tetrahedron Letters, 2000, 41, 1123-1126.
37. “Enantioselective Cycloadditions Catalyzed by Face Resolved Arene Chromium (0) Carbonyl Complexes”; Graham B. Jones, and Mustafa Guzel; Tetrahedron: Asymmetry, 1998, 9, 2023-2026.
38. “Refined Enantioselective Methylation Catalysts: Improved Routes to Bifunctional C5 Synthons”; Graham B. Jones, Mustafa Guzel, and Brant J. Chapman; Tetrahedron: Asymmetry, 1998, 9, 901-905.
39. “On the Origins of Enantioselectivity in Oxazaborolidine Mediated Carbonyl Reductions”; Graham B. Jones, Steven B. Heaton, Brant J. Chapman, and Mustafa Guzel; Tetrahedron: Asymmetry, 1997, 8, 3625-3636.

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Adı Soyadı Doç.Dr. Zübeyir BAYRAKTAROĞLU
E-Posta zbayraktaroglu@medipol.edu.tr
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi, İstanbul Tıp Fakültesi 2003 Fizyoloji, İstanbul Üniversitesi, İstanbul Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Fizyoloji Anabilim Dalı 2012 - 2016 Charite, Universitaetmedizin Berlin, Nöroloji ve Psikiyatri Bölümü, Nörofizik Grubu 2010 - 2012

Araştırma Alanları

Nörogörüntüleme, Biyoinformatik

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Doç.Dr. Bilal Ersen KERMAN
E-Posta bekerman@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Dr.Öğr.Üye. İlker KÖSE
E-Posta ikose@medipol.edu.tr
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi 1999 Gebze Teknik Üniversitesi, Bilgisayar Mühendisliği

Daha Önce Görev Yaptığı Yerler

Ar-Ge Direktörü, CompuGroup Medical A.Ş. (2009-2014) Proje Yöneticisi, Dünya Bankası, Sağlık Bakanlığı (2003-2009) Bilgi İşlem Şefi, İstanbul Ulaşm A.Ş. (1999-2003)

Araştırma Alanları

Sağlıkta veri madenciliği ve yapay sinir ağları uygulamaları, klinik ve yönetimsel karar destek sistemleri, elektronik sağlık kaydının anlamlı kullanımı, sağlık sistem mühendisliği

Seçili Yayınları / Tüm Yayınları

Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities)
1. Ilker Kose, Mehmet Gokturk, Kemal Kilic, An interactive machine-learning-based electronic fraud and abuse detection system in healthcare insurance, Applied Soft Computing, Volume 36, November 2015, Pages 283–299
2. Ilker kose, B. Ozge Elmas, The Correlation Analysis of Relative Values of DRGs and The National Public Health Service Tarrifs in Turkey, Journal of Health Systems and Policies 1 (1), 2018, Pages 53-71

Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında (Proceedings)basılan bildiriler
1. Ilker Kose, Seyma Guner, Bahadir Isguzerer, Muzaffer Ekin Sisli, A Case Study of the Extended Interactive Innovation Management Model in Insurance Company, European Conference on Innovation and Entrepreneurship 1, 375, 20-21 September 2018, Aveiro, Portugal
2. İlker KÖSE, Nihat AKPINAR, Murat GÜREL, Yakup ARSLAN, Hakan ÖZER, Nihat YURT, Yıldıray KABAK, Prof. Dr. Asuman DOĞAÇ, “Turkey’s National Health Information System (NHIS)” e-Challenges, 22-24 October 2008, Stokholm, Sweden
3. Yildiray KABAK, Prof. Dr. Asuman DOĞAÇ, İlker KÖSE, Nihat AKPINAR, Murat GÜREL, Yakup ARSLAN, Hakan ÖZER, Dr. Nihat YURT, Ahmet ÖZÇAM, “The Use of HL7 CDA in the National Health Information System (NHIS) of Turkey”, 9th International HL7 Interoperability Conference IHIC October 2008, Greece
4. Namli T., Aluc G., Sinaci A., Kose I., Akpinar N., Gurel M., Arslan Y., Ozer H., Yurt N., Kirici S., Sabur E., Ozcam A., Dogac A. “Testing the Conformance and Interoperability of NHIS to Turkey’s HL7 Profile” 9th International HL7 Interoperability Conference (IHIC) October 2008, Greece, pp. 63-68.
5. İ. Köse, Natalia Shvets, “Molecular Modeling in the ETOSAR Software”, International Modelling & Stability Conference, May 27-30 2003, Kiev
6. İ. Köse, N. Shvets, İ. Soğukpınar, “A Problem-Oriented Database as a Tool for the Data on the Structure-Activity Relationships Accumulation, Integration and Exchange”, 12th International Symposium on Artificial Intelligence and Neural Networks July 02-04, 2003, Çanakkale Turkey.

Yazılan uluslararası kitaplar veya kitaplarda bölümler
1. Kose, Ilker. 2017. “Science And Technology Policies In Turkey.” pp. 1759–74 in Researches on Science And Art in 21st Century Turkey, edited by H. ARAPGIRLIOGLU, A. ATIK, R. L. ELLIOT, and E. TURGEON. Ankara: Gece Kitaplığı
2. Kose, Ilker. 2018. "Veri Madenciliği, Teori, Uygulama ve Felsefesi", edited by Gökhan Silahtaroglu, Papatya Bilim, Istanbul
3. Kose, Ilker and Kemal Kilic. 2017. “Büyük Veri Bilimi Ile Sahteciliğin ve Suitsimalin Önlenmesi.” pp. 233–50 in Büyük Veri ve Açık Veri Analitiği: Yöntemler ve Uygulamalar, edited by Ş. Sağıroğlu and O. Koç. Ankara.

Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler
1. İlker KÖSE, Mehmet GÖKTÜRK, Kemal KILIÇ, "Sağlık Geri Ödeme Sistemlerinde Kural Dışı Davranış Tespitinde Aktör-Metâ Odaklı Yaklaşım", VII. Ulusal Tıp Bilişimi Kongresi, 2010, KKTC
2. İlker KÖSE, Mehmet GÖKTÜRK, Kemal KILIÇ, "Sağlık Sigortası Geri Ödemelerinde Kuraldışı Davranış Tespiti", YAEM 30. Ulusal Kongresi, 2010, İstanbul
Diğer yayınlar

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Adı Soyadı Dr.Öğr.Üye. Neşe ALTUNCU
E-Posta naysit@medipol.edu.tr
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Nörodejeneratif ve nörorejeneratif süreçlerde etkin olan moleküler ve hücresel mekanizmaların anlaşılmasında hücre kültürü ile araştırmalar yapmaktadır.

Seçili Yayınları / Tüm Yayınları

Demir O, Aysit N, Onder Z, Turkel N, Ozturk G, Sharrocks AD, Kurnaz IA. ETS-domain transcription factor Elk-1 mediates neuronal survival: SMN as a potential target. Biochem Biophys Acta, 1812:6, 652-66, 2011

Ozturk G., Cengiz N., Erdoğan E., Him A., Kaval Oğuz E., Yenidunya E., Aysit N.Two Distinct Types of Dying Back Axonal Degeneration In Vitro. Neuropathology and Applied Neurobiology 2012

Kurtuncu M., Kaya D., Zuliani L., Erdağ E., İçöz S., Uğurel E., Çavuş F., Aysit N., Biris O., Vincent A., Eraksoy M., Vural B., Akman-Demir G., and Tüzün. E. CACNA1H antibodies associated with headache with neurological deficits and cerebrospinal fluid lymphocytosis HANDL. Cephalalgia 33(2) 123–129! International Headache Society 2013.

Kuter N. · Aysit-Altuncu N. · Ozturk G. · Ozek E. The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in vitro.Neonatology 2018;113:360–365

Ayşit-Altuncu N, Ulusoy C, Öztürk G, Tüzün E. Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study. NeuroReport. 29(11):932–938, 2018

Kuter N., Aysit Altuncu N., Ozturk G., Ozek E. The Neuroprotective Effects of Hypothermia on Bilirubin Induced Neurotoxicity in Neuronal Cell Cultures. Pediatric Academic Societies Meeting 2017.USA poster presentation

M. Ozansoy, N. Altuncu, F. I. Aydınlı, E. N. Ekmekcioğlu & G. Öztürk ,Application of Axolotl Cell Suspension for the Treatment of Mouse Spinal Cord Injury, 15. National Neuroscience Convention 7-10 May 2017 Sakarya TURKEY oral presentation

Aysit N., Tuzun E.,Ozturk G. Ion Channels Antibody Role in the Neuron’s Survival. Neuroscience Society For Neuroscience 2015.USA poster presentation

Aysit N., Bahceci B., Ozturk G. The Role Of FGF, B 27 and FCS İn Neuron’s Survival in Newborn Cerebral Kortex National Neuroscience Convention 2015. Konya TURKEY poster presentation

Ayşit N. The Role of Elk-1 and Pea-3 Proteins in Axon Regeneration and Degeneration 6.Cellular Neuroscience Days , 2013. Gaziantep TURKEY. poster presentation

Ozturk R.I, Aysit N. Nodose Ganglion Culture Protocol in Adult Mice. National Neuroscience Convention 2013 İzmir TURKEY poster presentation

Aysit N., Ozturk G., The Role Of FGF, B 27 and FCS İn Neuron’s Survival in Newborn Hippocampus 4th International Conference on Cell Membranes and Oxidative Stress: Calcium Signaling and TRP Channels 2012. Isparta TURKEY poster presentation.

Soysal Z. B. Aysit N. Culture of Mouse Hippocampus2sc Annual Science Fair, Medipol University, 2012. Istanbul TURKEY poster presentation.

Yıldız A. Aysit N. Culture of Mouse Cerebellum. 2sc Annual Science Fair, Medipol University, May 2012. Istanbul TURKEY poster presentation

Kabakcı M.R, Aysit N..Comparison of cerebellum tissue explant and cell culture. 2sc Annual Science Fair, Medipol University, May 2012 . Istanbul TURKEY poster presentatio.

Ödemiş H., Aysit N. Comparison of cortex tissue explant and cell culture 2sc Annual Science Fair, Medipol University,May 2012 . Istanbul TURKEY poster presentation.

Budak E. Aysit N..Comparison of liver tissue explant and cell culture2scAnnual Science Fair, Medipol University, May 2012 . Istanbul TURKEY poster presentation

Haksever F.P., Aysit N.. Comparison of olfactor bulb tissue explant and cell culture açıklaması2sc Annual Science Fair, Medipol University, May 2012 . Istanbul TURKEY poster presentation

Ates B., Aysit N..Comparison of lung tissue explant and cell culture 2sc Annual Science Fair, Medipol University, May 2012 . Istanbul TURKEY poster presentation

Bayraktar M , Aysit N.. Adult Axolotls Brain 4.th Annual Science Fair, Medipol University, May 2015. Istanbul TURKEY poster presentation


Öztürk G., Him A. Cengiz N., Kaval Oğuz E. Yenidunya E. ,Aysit N.. Evidence Of Transneuronal Degeneration in Vitro Neuroscience SOCİETY FOR NEUROSCİENCE 2011 USA . poster presentation

Ayşit, N., Öztürk, G., Aksan Kurnaz, I., The role of SRF, Elk 1, Elk p, Pea 3 SAP 1 and proteins in axon regeneration, 10th National Neuroscience Congress, , 2011. İstanbul TURKEY poster presentation.

Oztürk, G., Ayşit, N., Kurnaz, I.A, Demir, Ö. ETS Transcription Factors Relate to Axotomy and Neuronal Death. 8th National Congress of Neuroscience, 2009 Bolu TURKEY poster presentation.

Öztürk, G., Ayşit, N., Yardım, Y. E. Three Dimensional Primer Sense Neuron-Epidermis Co-Culture. 8th National Congress of Neuroscience, 2009. Bolu, TURKEY inveted talk.




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Adı Soyadı Dr.Öğr.Üye. Ayşe İSTANBULLU TOSUN
E-Posta atosun@medipol.edu.tr
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi 1992-1998 İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Mikrobiyoloji ABD

Daha Önce Görev Yaptığı Yerler

Amerikan Hastanesi, Synlab Laboratuvarı, Alman Hastanesi, Ahenk Laboratuvarı

Araştırma Alanları

1.Antimikrobiyal direnç 2.Moleküler testler 3.Hastane infeksiyonları

Seçili Yayınları / Tüm Yayınları

Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities)
7.1.

7.1.1.Effect of a moustache on nasal Staphylococcus aureus colonisation and nasal cytology results in men E Soylu, I Orhan, A Cakir, A Istanbullu, G Altin, R Yilmazer, O F Calim, The Journal of Laryngology & Otology 01/2015; 129(02):1-4. DOI:10.1017/S002221511400334X · 0.67 Impact Factor

7.1.2.Spread of NDM-1-Producing Enterobacteriaceae in a Neonatal Intensive Care Unit in Istanbul, Turkey,Laurent Poirel, Mesut Yilmaz, Ayse Istanbullu, Ferhat Arslan, Ali Mert, Sandrine Bernabeu, Patrice Nordmann,Antimicrobial Agents and Chemotherapy 02/2014; 58(5). DOI:10.1128/AAC.02047-13 · 4.48 Impact Factor

7.1.3.OP5-7 Diversification of HIV1 subtypes in Turkey – a country with a low HIV endemicity,K. Midilli, G. Yilmaz, M. A. Kuşkucu,S. Ergin, A. İstanbullu, S. Türkoğlu, A. Kaygusuz, K. Altaş,Journal of Clinical Virology 09/2009; 46. DOI:10.1016/S1386-6532(09)70071-X · 3.02 Impact Factor

7.1.4.Phylogenetic analysis of human influenza viruses in three consecutive seasons in Istanbul, K. Midilli, G. Yilmaz, S. Ergin, G. Aygun, A. Istanbullu, S. Turkoglu, K. Altas, Journal of Clinical Virology 08/2006; 36. DOI:10.1016/S1386-6532(06)80771-7 · 3.02 Impact Factor

7.2. Uluslararası diğer hakemli dergilerde yayınlanan makaleler

7.3. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında (Proceedings)basılan bildiriler

Diversification of HIV-1 subtypes in Turkey- a country with a low HIV endemicity K Midilli, G Yılmaz ,MA Kuşkucu, S Ergin, A. İstanbullu, S. Türkoğlu, A Kaygusuz, K Altaş 12th ESCV, İstanbul- Journal of Clinical Virology Suppl. 1 (2009) OP-5-7

Phylogenetic analysis of human influenza viruses in three consecutive seasons in İstanbul K Midilli, G Yılmaz , S Ergin, G.Aygün, A. İstanbullu, S. Türkoğlu, K Altaş Journal of Clinical Virology (2006) Vol 36(Suppl 2)

7.4. Yazılan uluslararası kitaplar veya kitaplarda bölümler

7.5. Ulusal hakemli dergilerde yayınlanan makaleler

ÇOCUK HASTALARIN ABSE MATERYALLERİNDEN İZOLE EDİLEN ANAEROB BAKTERİLER VE ANTİMİKROBİK DİRENÇ DURUMLARI. H Bahar, M Mamal Torun, M Demirci, N Sever, A İstanbullu. ANKEM Dergisi 16:4. 2002:486-91

7.6. Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler

7.6.1.
Demir Eksikliği Anemisinin HbA1c Düzeylerine Etkisi. G. Ülfer, Y.Baskın, O.Olmuşçelik, A.İstanbullu Tosun, N.Emekli, KBUD Kongresi, 2014, Antalya

HIV ile infekte, tedavi altındaki hastalarda antiretroviral direncin araştırılması. K Midilli, G Yılmaz, A. İstanbullu, S. Ergin, M Kuşkucu, R.Öztürk, V Korten, S. Çalangu, A. Çağatay, K. Altaş. 2. Ulusal viroloji Kongresi Sözel Sunum 012005 Antalya-Kemer

Türkiye'de ilk kez saptanan rekombinant HIV-1 ile infekte iki olgu. G Yılmaz ,K Midilli, A. İstanbullu, S. Türkoğlu, S. Çalangu, K Altaş 2. Ulusal AIDS Sempozyumu 2004 İzmir-Foça

HIV ile infekte naif hastalarda genotipik yöntemle anteretrovirallere direncin araştırılması G Yılmaz ,K Midilli, A. İstanbullu, S. Türkoğlu, Ö Nazlıcan,S. Çalangu, K Altaş 2. Ulusal AIDS Sempozyumu 2004 İzmir-Foça

ÜROLOJİ POLİKLİNİĞİNDE TAKİP EDİLEN HASTALARIN İDRAR ÖRNEKLERİNDEN İZOLE EDİLEN BAKTERİLER VE BU BAKTERİLERİN TEDAVİDE SIK KULLANILAN BAZI ANTİBİYOTİKLERE KARŞI DİRENÇ ORANLARI. Aygün G, İstanbullu A, Özdamar M, Yanık S, Yaşar H, Parlakgül D, Aşırdizer S, Özbek C, Ergüven O, Altaş K. XI. KLİMİK Kongresi, İstanbul-2003;s:302

TOPLUM VE HASTANE KAYNAKLI ÜRİNER SİSTEM İNFEKSİYONLARINDAN İZOLE EDİLEN ESCHERİCHİA COLİ KÖKENLERİNDE ANTİBİYOTİK DİRENCİ. Gökhan AYGÜN, Sema YANIK, Funda KOÇAK, Melda ÖZDAMAR, Serpil AŞIRDİZER, Deniz PARLAKGÜL, Hatice YAŞAR, Ayşe İSTANBULLU, Oray ERGÜVEN, Günay CAN, Kemal ALTAŞ. XI. KLİMİK Kongresi, İstanbul-2003;s:344

2003 CERRAHPAŞA TIP FAKÜLTESİ HASTANE İNFEKSİYONLARI PREVALANS ÇALIŞMASI. Günay Can, Gökhan Aygün, Pakize Aygün, Serpil Erol, Nazan Küçük, Selahattin Aydınlı, Mücahit Yemişen, Birgül Mete, Aslı Demirel, Sema Yanık, Asuman Sıdan, Ayşe İstanbullu, Melda Özdamar, Recep Öztürk, Yaşar Bağdatlı. Hastane İnfeksiyonları Dergisi 2004:8 ek 2; Hastane İnfeksiyonları Kongresi Ankara-2004;s:54

PEDİYATRİK NOZOKOMİYAL İSHALLERDE VİRAL ETKENLERİN SAPTANMASI. M Özdamar, K Midilli, A İstanbullu, M Samastı, S Türkoglu, K Altaş. XXXI. Türk Mikrobiyoloji kongresi Kuşadası 2004

HASTANEMİZ KLİNİK MİKROBİYOLOJİ LABORATUVARINDA 2002 YILINDA İDRAR ÖRNEKLERİNDEN ÜRETİLEN HAEMOPHİLUS CİNSİ BAKTERİLER Aygün G. Yücel N. İstanbullu A. Yanık S. Karatoka B. Aşırdizer S. Parlakgül D. Altaş K. XI.KLİMİK Kongresi, İstanbul-2003;s:344

SALGIN DÖNEMİNDE HASTANEMİZ LABORATUVARINDA PCR YÖNTEMİYLE İZOLE EDİLEN İNFLUENZA VİRUSLARI. K Midilli, A İstanbullu, G Yılmaz, S Türkoğlu

SÖZLÜ SUNUM

1.Tam İdrar Tetkikine Mikrobiyolojik Yaklaşım, İdrar Değerlendirmesi Bilgi Güncelleme Kursu, Medipol Üniversitesi Sürekli Eğitim Merkezi, İstanbul Türkiye; 01/2015

2.Bir vaka dolayısı ile; nadir bir mikroorganizmada NDM-1, A.İ.Tosun, M.Özdamar, M.Yılmaz, XXXVI.Türk Mikrobiyoloji Kongresi Konuşma Özetleri ve Bildirileri Kitabı SS03 s392, Belek-Antalya Türkiye; 10/2014

3.İstanbul'da Karbapenemaz(NDM-1 ve KPC) Tehdidi:Çok Geç Olmadan Durdurulmalı, M.Yılmaz, A.İstanbullu, F.Arslan, L.Poirel, P.Nordmann, A.Mert 21-25 Mayıs 2014, Antalya, Türkiye

4. 2004-2005 yılları arasında saptanan Influenza A Virus kökenlerinin moleküler analizi 2005 Antalya-Kemer

5. HASTANEMİZDE İZOLE EDİLEN ESCHERİCHİA COLİ VE KLEBSİELLA PNEUMONİAE KÖKENLERİNİN PLAZMİD KÖKENLİ AMPC BETA-LAKTAMAZ VARLIĞI YÖNÜNDEN ARAŞTIRILMASI. A İstanbullu, K Midilli, M Özdamar, S Yanık, G Aygün, K
Altaş. XXXI. Türk Mikrobiyoloji Kongresi Kuşadası 2004


7.7. Diğer yayınlar

8. Ödüller
5.Türkiye EKMUD Kongresi Sözel Bildiri 3.lük Ödülü, İstanbul'da Karbapenemaz(NDM-1 ve KPC) Tehdidi:Çok Geç Olmadan Durdurulmalı, M.Yılmaz, A.İstanbullu, F.Arslan, L.Poirel, P.Nordmann, A.Mert 21-25 Mayıs 2014, Antalya, Türkiye

2. Ulusal Viroloji Kongresi Sözel sunum 1. lik ödülü "2004-2005 yılları arasında saptanan Influenza A Virus kökenlerinin moleküler analizi"2005 Antalya-Kemer

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Adı Soyadı Dr.Öğr.Üye. Taha KELEŞTEMUR
E-Posta tkelestemur@medipol.edu.tr
Detay Öz Geçmiş
Medya

Istanbul Universitesi 2009 İstanbul Medipol Üniversitesi, Necmettin Erbakan Üniversitesi

Daha Önce Görev Yaptığı Yerler

Yeditepe Üniversitesi

Araştırma Alanları

Travmatik Beyin Hasarı, Epilepsi, Hipoksi

Seçili Yayınları / Tüm Yayınları

Kelestemur T “A Reproducible Model of Traumatic Brain Injury in Rats: The Roles of Phosphorylated JNK-1/2” FEPS September 2012 / Santiago de Compostela / Spain

Keleştemur T “Investigation of the Pathophysiological Changes in the Signalling Pathway and Sensory and Motor Behavioral Changes after Traumatic Brain Injury in Rats” TFBD 38 th. National Physiology Meeting September 2012 / Trabzon / Turkey

Keleştemur T “Investigation the Effects of Memantine and Melatonin Treatment after Traumatic Brain Injury in Mice” 11th National Neuroscience Meeting April 2013 /Izmir / Turkey

Keleştemur T “P2x7 Reseptör Baskılanması Ve Aktivasyonunun Beyin- Epileptiform Aktivitesi, Mikrodolaşımı Ve Hücre İçi Sinyal İletim Molekülleri Üzerine Olan Etkileri" 40. Ulusal Fizyoloji Kongresi Eylül 2014 Kayseri / Türkiye

Keleştemur T "Inhibition but not activation of P2X7 receptors improves brain epileptiform activity in mice: Role of NOS activity" 44th Annual Meeting of the Society for Neuroscience November 2014 / Washington D.C. / USA

Kilic E, Reitmeir R, Kilic U, Caglayan AB, Beker MC et al. : HMG-CoA Redcutase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Conta-Lesional Pyramidal Tract Plasticity After Focal Cerebral Ischemia. Fron. Cell. Neurosci.. (8) : 422-432, 2014

Beker M.C., Caglayan A.B., Kelestemur T., Caglayan B., Yalcin E. : Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation. Oncotarget. 6 (29) : 1-11, 2015

Taha Kelestemur,Burak Yulug,Ahmet Burak Caglayan,Mustafa Caglar Beker,Ulkan Kilic,Berrak Caglayan,Esra Yalcin,Reyhan Zeynep Gundogdu,Ertugrul Kilic : Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine. Neuroscience Letters. 0 (0) : 0-0, 2015

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Adı Soyadı Dr.Öğr.Üye. Mustafa Çağlar BEKER
E-Posta mcbeker@medipol.edu.tr
Detay Öz Geçmiş
Medya

Yeditepe Üniversitesi 2012 İstanbul Medipol Üniversitesi

Daha Önce Görev Yaptığı Yerler

-

Araştırma Alanları

Beyin Felci, Deney Hayvanlarında Davranış Testleri, Plastisite

Seçili Yayınları / Tüm Yayınları

SCI, SSCI, AHCI indekslerine giren dergilerde yayınlanan makaleler

1. Caglayan B, Caglayan AB, Beker MC, Yalcin E, Beker M, Kelestemur T, Sertel E, Ozturk G, Sahin F, Kilic E, (2017) “Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice” Exp. Neurol. 29;296:23-31. doi: 10.1016/j.expneurol.2017.06.024.
2. Demirci S, Dogan A, Basak Turkmen N, Telci D, Caglayan AB, Beker MC, Kilic E, Ozkan F, Dede B, Sahin F, (2017) “Poloxamer P85 increases anticancer activity of Schiff base against prostate cancer in vitro and in vivo” Anticancer Drugs. doi: 10.1097/CAD.0000000000000528.
3. Beker MC, Caglayan B, Yalcin E, Caglayan AB, Turkseven S, Gurel B, Kelestemur T, Sertel E, Sahin Z, Kutlu S, Kilic U, Baykal AT, Kilic E, (2017) “Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT” Mol Neurobiol. doi: 10.1007/s12035-017-0524-4.
4. Kilic U, Caglayan AB, Beker MC, Gunal MY, Caglayan B, Yalcin E, Kelestemur T, Gundogdu RZ, Yulug B, Yilmaz B, Kerman BE, Kilic E, (2017) “Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice” Redox Biol. 12:657-665. doi: 10.1016/j.redox.2017.04.006.
5. Eren Z, Gunal MY, Ari E, Coban J, Cakalagaoglu F, Caglayan B, Beker MC, Akdeniz T, Yanikkaya G, Kilic E, Kantarci G, (2016) “Pleiotropic and Renoprotective Effects of Erythropoietin Beta on Experimental Diabetic Nephropathy Model”. Nephron 132:292-300. doi: 10.1159/000444649.
6. Kartal O, Aydinoz S, Kartal AT, Kelestemur T, Caglayan AB, Beker MC, Karademir F, Suleymanoglu S, Kul M, Yulug B, Kilic E (2016) “Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3”. Metabolic brain disease. 31(4):827-35. doi: 10.1007/s11011-016-9816-z.
7. Kelestemur T, Yulug B, Caglayan AB, Beker MC, Kilic U, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E (2016) “Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine”. Neuroscience letters 612:92-97. doi: 10.1016/j.neulet.2015.11.043.
8. Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Yulug B, Kilic U, Hermann DM, Kilic E (2015) “Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation”. Oncotarget 6:30604-30614. doi: 10.18632/oncotarget.5773.
9. Kilic E, Reitmeir R, Kilic U, Caglayan AB, Beker MC, Kelestemur T, Ethemoglu MS, Ozturk G, Hermann DM (2014) “HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia”. Frontiers in cellular neuroscience 8:422. doi: 10.3389/fncel.2014.00422.

Uluslararası hakemli konferans/sempozyumların bildiri kitaplarında yer alan yayınlar

1. Poster- Beker MC, Caglayan AB, Yalcin E, Kilic U, Baykal AT, Gurel B, Kilic E, “Proteomic Approach To Circadian Rhythm After Brain Injury”, 7th EMBO Meeting, Germany, 2016.
2. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Sarma M, Kilic E, “The role of cerebral dopamine neurotrophic factor (CDNF) in the development of brain plasticity and repair: Role of axonal outgrowth inhibitors and cell signaling”, 7th EMBO Meeting, Germany, 2016.
3. Poster- Caglayan B, Caglayan AB, Beker MC, Kilic U, Yalcin E, Altunay S, Kelestemur T, Gunal MY, Hanoglu L, Yulug B, Kilic E, “Repetitive transcranial magnetic stimulation promotes neuronal survival in the acute phase and stroke- recovery in the sub-acute phase of focal cerebral ischemia” 7th EMBO Meeting, Germany, 2016.
4. Poster- Kilic U, Caglayan AB, Beker MC, Elibol B, Beker M, Altug-Tasa B, Ozcicek I, Ozen M, Yilmaz B, Kilic E, “Melatonin Promotes Stroke Recovery By Stimulating Axonal Projections And Neurogenesis”, 7th EMBO Meeting, Germany, 2016.
5. Poster- Yalcin E, Caglayan AB, Beker MC, Gurel B, Kelestemur T, Caglayan B, Dalay A, Dilden A, Altunay S, Sertel E, Yulug B, Kilic U, Kilic E, “Oatp1a5 transporter is a gateway for pharmacological compounds to the ischemic brain” 7th EMBO Meeting, Germany, 2016.
6. Poster- Kilic U, Beker MC, Caglayan AB, Elibol B, Karakas M, Altug B, Gok O, Kelestemur T, Kilic E, “Melatonin promotes neurological recovery, peri-lesional tissue remodeling, and contralesional pyramidal tract plasticity after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
7. Poster- Kelestemur T, Caglayan AB, Beker MC, Kilic U, Altunay S, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E, “Effects of normobaric oxygen treatment on brain injury after hypoxia-ischemia in newborn mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
8. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Ozturk G, Kilic E “The role of neuronal expression of P2X7 receptors in the processes of brain injury in mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
9. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “Inhibition but not activation of P2X7 receptors improves brain epileptiform activity in mice: Role of iNOS activation” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
10. Poster- Beker MC, Caglayan AB Kelestemur T, Yalcin E, Ozturk G, Kilic E, “Roles of oxygen treatment in the development of ischemic brain injury, signal transduction and brain microcirculation after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
11. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “The phosphatidylinositol-3 kinase/Akt pathway mediates melatonin’s neuroprotective activity after focal cerebral ischemia” The 5th EMBO Meeting, 2013.
12. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Gundogdu RZ, Kilic E “Roles of P2X7 receptors in neuronal injury after optic nerve transaction and focal cerebral ischemia” The 5th EMBO Meeting, 2013.

Ulusal hakemli konferans/sempozyumların bildiri kitaplarında yer alan yayınlar

1. Sözlü Sunum- Keleştemur T, Çağlayan AB, Beker MC, Çağlayan B, Yalçın E, Sertel E, Kılıç E, “Beyin Felci Sonrası Gelişen Patofizyolojik Süreçlerin İleri Mikroskopi Teknikleri ile İncelenmesi” 15. Ulusal Sinirbilim Kongresi, Sakarya, 2017.
2. Sözlü Sunum- Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Dalay A, Altunay A, Sertel E, Kilic E, “Effects of Circadian Rhythm on Brain Injury and Related Molecular Mechanisms” 42. Ulusal Fizyoloji Kongresi, 20/32, Düzce, 2016.
3. Sözlü Sunum- Kelestemur T, Beker MC, Caglayan AB, Yalcin E, Altunay S, Dalay A, Sertel E, Dilden A, Caglayan B, Kilic E, “Role of Normobaric Oxygen Treatment on Newborn Hypoxia –Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, OC23, Düzce/ Turkey, 2016.
4. Poster- Yalcin E, Caglayan AB, Beker MC, Kelestemur T, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kilic E, “The role of solute carrier Oatp1a4 in brain injury pharmacotherapy” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress , PC108, Düzce/Turkey, 2016.
5. Poster- Kilic U, Elibol B, Beker MC, Caglayan AB, Tasa-Altug B, Beker M, Ozen B, Yilmaz B, Kilic E, “Plasticity-Promoting Effect of Melatonin After Experimental Cerebral Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC112, Düzce/Turkey, 2016.
6. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Saarma M, Kilic E, “Effect of Neurotrophic factors CDNF and MANF Brain Plasticity and Repair After Brain Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC118, Düzce/ Turkey, 2016.
7. Sözlü Sunum- Caglayan AB, Yalcin E, Beker MC, Caglayan B, Kelestemur T, Ozturk G, Kilic E “In vivo ve in vitro P2X7 receptörü aracılı nöronal sağkalım mekanizması” 13. Ulusal Sinirbilim Kongresi, 2015.
8. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptörünün farede epilepsi sonrası rolü” 13. Ulusal Sinirbilim Kongresi, 2015.
9. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Caglayan B, Kilic E “Melatonin ve normobarik oksijen tedavisinin reperfüzyon hasarına etkileri” 13. Ulusal Sinirbilim Kongresi, 2015.
10. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptör baskılanması ve aktivasyonunun beyin epileptiform aktivitesi, mikrodolaşımı ve hücre içi sinyal iletim molekülleri üzerine olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014.
11. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Ozturk G, Kilic E “Normobarik oksijen tedavisinin beyin felci sonrası gelişen hasar, sinyal mekanizmaları ve beyin kan dolaşımına olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014
12. Sözlü sunum- Kilic U, Gok O, Karakas M, Elibol B, Beker MC, Caglayan AB, Kilic E “İskemi sonrası fonksiyonel iyileşmeyi sağlayan plastisiteye bağlı moleküler mekanizmalarda melatoninin etkinliğinin araştırılması” 40. Ulusal Fizyoloji Kongresi, 2014.
13. Sözlü sunum- Kelestemur T, Caglayan AB, Beker MC, Yilmaz B, Kilic E “Sıçanlarda memantin ve melatonin tedavisinin travmatik beyin hasarı sonrası etkilerinin araştırılması” 11. Ulusal Sinirbilim Kongresi, 2013.
14. Poster- Caglayan AB, Beker MC, Kilic E, Kilic U “P2X7 reseptörlerinin fare optik kesisi ve fokal iskemi modelleriyle oluşturulan nöronal hasar üzerine etkisi” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
15. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “Fosfatidil inozitol-3 kinaz/AKT sinyal yolağının Melatoninin iskemi sonrası nöroprotektif etkisinde rolü” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
16. Sözlü sunum- Seker FB, Kilic U, Caglayan AB, Ekimci N, Cevreli B, Beker MC, Demirci S, Dogan A, Yilmaz B, Kilic E “Profiklaktik olarak uygulanan 3-Hidroksi-3-Metilglutaril Koenzim A Redüktaz İnhibitörlerinin penisilinle indüklenen beyin epileptik aktivitesine etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.
17. Sözlü-sunum- Kilic U, Caglayan B, Ethemoglu, Caglayan AB, Beker MC, Ekimci N, Kilic E “3-Hydroxy-Methykgkutaryl Coenzyme A reductase inhibitörü rosuvastatinin beyin felci sonrası beyin plastisitesi ve onarım üzerine olan etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.






text
Adı Soyadı Dr.Öğr.Üye. Ahmet Burak ÇAĞLAYAN
E-Posta abcaglayan@medipol.edu.tr
Detay Öz Geçmiş
Medya

Yeditepe Üniversitesi 2011 Sinirbilim / İstanbul Medipol Üniversitesi

Daha Önce Görev Yaptığı Yerler

Yeditepe Üniversitesi, Bezmialem Vakıf Üniversitesi

Araştırma Alanları

Beyin Felci sonrası Plastisite ve Fonksiyonel Geri Kazanım

Seçili Yayınları / Tüm Yayınları

Uluslararası Yayınlar
1. Kilic U, Caglayan AB, Beker MC, Gunal MY, Caglayan B, Yalcin E, Kelestemur T, Gundogdu RZ, Yulug B, Yılmaz B, Kerman BE, Kilic E. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol. 2017 Aug;12:657-665. doi: 10.1016/j.redox.2017.04.006. Epub 2017 Apr 5.
2. Caglayan B, Caglayan AB, Beker MC, Yalcin E, Beker M, Kelestemur T, Sertel E, Ozturk G, Kilic U, Sahin F, Kilic E. Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice. Exp Neurol. 2017 Jun 29;296:23-31. doi: 10.1016/j.expneurol.2017.06.024.
3. Demirci S, Doğan A, Başak Türkmen N, Telci D, Çağlayan AB, Beker MÇ, Kiliç E, Özkan F, Dede B, Şahin F. Poloxamer P85 increases anticancer activity of Schiff base against prostate cancer in vitro and in vivo. Anticancer Drugs. 2017 Jun 13. doi: 10.1097/CAD.0000000000000528.
4. Beker MC, Caglayan B, Yalcin E, Caglayan AB, Turkseven S, Gurel B, Kelestemur T, Sertel E, Sahin Z, Kutlu S, Kilic U, Baykal AT, Kilic E. Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT. Mol Neurobiol. 2017 Apr 18. doi: 10.1007/s12035-017-0524-4.
5. Doeppner TR, Kaltwasser B, Sanchez-Mendoza EH, Caglayan AB, Bähr M, Hermann DM. Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3ß inhibition-independent pathways. J Cereb Blood Flow Metab. 2017 Mar;37(3):914-926. doi: 10.1177/0271678X16647738.
6. Eren Z, Gunal MY, Ari E, Coban J, Cakalagaoglu F, Caglayan AB, Beker MC, Akdeniz T, Yanikkaya G, Kilic E, Kantarci G. Pleiotropic and Renoprotective Effects of Erythropoietin Beta on Experimental Diabetic Nephropathy Model. Nephron. 2016 132:292-300. doi: 10.1159/000444649.
7. Doğan A, Demirci S, Türkmen NB, Çağlayan AB, Aydın S, Telci D, Kılıç E, Şahin K, Orhan C, Tuzcu M, Ekici AI, Şahin F. Schiff Base-Poloxamer P85 Combination Prevents Prostate Cancer Progression in C57/Bl6 Mice. Prostate. 2016 Nov;76(15):1454-63. doi: 10.1002/pros.23229.
8. Kartal Ö, Aydınöz S, Kartal AT, Kelestemur T, Caglayan AB, Beker MC, Karademir F, Süleymanoğlu S, Kul M, Yulug B, Kilic E. Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3. Metab Brain Dis. 2016 Aug;31(4):827-35. doi: 10.1007/s11011-016-9816-z.
9. Kelestemur T, Yulug B, Caglayan AB, Beker MC, Kilic U, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E. Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine. Neurosci Lett. 2016 Jan 26;612:92-7. doi: 10.1016/j.neulet.2015.11.043.
10. Hermann DM, Zechariah A, Kaltwasser B, Bosche B, Caglayan AB, Kilic E, Doeppner TR. Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia. Neurobiol Dis. 2015 Nov;83:16-25. doi: 10.1016/j.nbd.2015.08.018.
11. Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Yulug B, Kilic U, Hermann DM, Kilic E. Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation. Oncotarget. 2015 Oct 13;6(31):30604-14. doi: 10.18632/oncotarget.5773.
12. Seker FB, Kilic U, Caglayan B, Ethemoglu MS, Caglayan AB, Ekimci N, Demirci S, Dogan A, Oztezcan S, Sahin F, Yilmaz B, Kilic E. HMG-CoA reductase inhibitor rosuvastatin improves abnormal brain electrical activity via mechanisms involving eNOS. Neuroscience. 2015 Jan 22;284:349-59. doi: 10.1016/j.neuroscience.2014.10.014.
13. Kilic E, Reitmeir R, Kilic Ü, Caglayan AB, Beker MC, Kelestemur T, Ethemoglu MS, Ozturk G, Hermann DM. HMG-CoA Reductase Inhibition Promotes Neurological Recovery, Peri-Lesional Tissue Remodeling, and Contralesional Pyramidal Tract Plasticity after Focal Cerebral Ischemia. Front Cell Neurosci. 2014 Dec 11;8:422. doi: 10.3389/fncel.2014.00422.
14. Doğan A, Demirci S, Cağlayan AB, Kılıç E, Günal MY, Uslu U, Cumbul A, Sahin F. Sodium pentaborate pentahydrate and pluronic containing hydrogel increases cutaneous wound healing in vitro and in vivo. Biol Trace Elem Res. 2014 Dec;162(1-3):72-9. doi: 10.1007/s12011-014-0104-7.
15. Sonay AY, Caglayan AB, Culha M. Synthesis of Peptide Mediated Au Core–Ag Shell Nanoparticles as Surface-Enhanced Raman Scattering Labels. Plasmonics. 2012 7:77-86. doi: 10.1007/s11468-011-9278-4.

Özetler
Uluslararası Bildiriler
1. Poster- Beker MC, Caglayan AB, Yalcin E, Kilic U, Baykal AT, Gurel B, Kilic E, “Proteomic Approach To Circadian Rhythm After Brain Injury”, 7th EMBO Meeting, Germany, 2016.
2. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Sarma M, Kilic E, “The role of cerebral dopamine neurotrophic factor (CDNF) in the development of brain plasticity and repair: Role of axonal outgrowth inhibitors and cell signaling”, 7th EMBO Meeting, Germany, 2016.
3. Poster- Caglayan B, Caglayan AB, Beker MC, Kilic U, Yalcin E, Altunay S, Kelestemur T, Gunal MY, Hanoglu L, Yulug B, Kilic E, “Repetitive transcranial magnetic stimulation promotes neuronal survival in the acute phase and stroke- recovery in the sub-acute phase of focal cerebral ischemia” 7th EMBO Meeting, Germany, 2016.
4. Poster- Kilic U, Caglayan AB, Beker MC, Elibol B, Beker M, Altug-Tasa B, Ozcicek I, Ozen M, Yilmaz B, Kilic E, “Melatonin Promotes Stroke Recovery By Stimulating Axonal Projections And Neurogenesis”, 7th EMBO Meeting, Germany, 2016.
5. Poster- Yalcin E, Caglayan AB, Beker MC, Gurel B, Kelestemur T, Caglayan B, Dalay A, Dilden A, Altunay S, Sertel E, Yulug B, Kilic U, Kilic E, “Oatp1a5 transporter is a gateway for pharmacological compounds to the ischemic brain” 7th EMBO Meeting, Germany, 2016.
6. Poster- Kilic U, Beker MC, Caglayan AB, Elibol B, Karakas M, Altug B, Gok O, Kelestemur T, Kilic E, “Melatonin promotes neurological recovery, peri-lesional tissue remodeling, and contralesional pyramidal tract plasticity after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
7. Poster- Kelestemur T, Caglayan AB, Beker MC, Kilic U, Altunay S, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E, “Effects of normobaric oxygen treatment on brain injury after hypoxia-ischemia in newborn mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2015. Online.
8. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Ozturk G, Kilic E “The role of neuronal expression of P2X7 receptors in the processes of brain injury in mice” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
9. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “Inhibition but not activation of P2X7 receptors improves brain epileptiform activity in mice: Role of iNOS activation” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
10. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Ozturk G, Kilic E, “Roles of oxygen treatment in the development of ischemic brain injury, signal transduction and brain microcirculation after focal cerebral ischemia” Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2014. Online.
11. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “The phosphatidylinositol-3 kinase/Akt pathway mediates melatonin’s neuroprotective activity after focal cerebral ischemia” The 5th EMBO Meeting, 2013.
12. Poster- Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Gundogdu RZ, Kilic E “Roles of P2X7 receptors in neuronal injury after optic nerve transaction and focal cerebral ischemia” The 5th EMBO Meeting, 2013.

Ulusal Bildiriler ve Sözlü Sunumlar
1. Poster- Kelestemur T, Caglayan AB, Beker MC, Caglayan B, Yalcin E, Sertel E, Kilic E “Investigation of Pathophysiological Processes with Advanced Microscopy Techniques after Cerebral Ischemia” 15. Ulusal Sinirbilim Kongresi, Sakarya, 2017.
2. Sözlü Sunum- Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Dalay A, Altunay A, Sertel E, Kilic E, “Effects of Circadian Rhythm on Brain Injury and Related Molecular Mechanisms” 42. Ulusal Fizyoloji Kongresi, 20/32, Düzce, 2016.
3. Sözlü Sunum- Kelestemur T, Beker MC, Caglayan AB, Yalcin E, Altunay S, Dalay A, Sertel E, Dilden A, Caglayan B, Kilic E, “Role of Normobaric Oxygen Treatment on Newborn Hypoxia –Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, OC23, Düzce/ Turkey, 2016.
4. Poster- Yalcin E, Caglayan AB, Beker MC, Kelestemur T, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kilic E, “The role of solute carrier Oatp1a4 in brain injury pharmacotherapy” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress , PC108, Düzce/Turkey, 2016.
5. Poster- Kilic U, Elibol B, Beker MC, Caglayan AB, Tasa-Altug B, Beker M, Ozen B, Yilmaz B, Kilic E, “Plasticity-Promoting Effect of Melatonin After Experimental Cerebral Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC112, Düzce/Turkey, 2016.
6. Poster- Caglayan AB, Beker MC, Caglayan B, Altunay S, Dalay A, Dilden A, Sertel E, Kelestemur T, Yalcin E, Kilic U, Saarma M, Kilic E, “Effect of Neurotrophic factors CDNF and MANF Brain Plasticity and Repair After Brain Ischemia” Turkish Society ofPhysiological Sciences 42nd National Physiology Congress, PC118, Düzce/ Turkey, 2016
7. Sözlü Sunum- Caglayan AB, Yalcin E, Beker MC, Caglayan B, Kelestemur T, Ozturk G, Kilic E “In vivo ve in vitro P2X7 receptörü aracılı nöronal sağkalım mekanizması” 13. Ulusal Sinirbilim Kongresi, 2015.
8. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptörünün farede epilepsi sonrası rolü” 13. Ulusal Sinirbilim Kongresi, 2015.
9. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Caglayan B, Kilic E “Melatonin ve normobarik oksijen tedavisinin reperfüzyon hasarına etkileri” 13. Ulusal Sinirbilim Kongresi, 2015.
10. Poster- Kelestemur T, Caglayan AB, Beker MC, Yalcin E, Ozturk G, Kilic E “P2X7 reseptör baskılanması ve aktivasyonunun beyin epileptiform aktivitesi, mikrodolaşımı ve hücre içi sinyal iletim molekülleri üzerine olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014.
11. Poster- Beker MC, Caglayan AB, Kelestemur T, Yalcin E, Ozturk G, Kilic E “Normobarik oksijen tedavisinin beyin felci sonrası gelişen hasar, sinyal mekanizmaları ve beyin kan dolaşımına olan etkileri” 40. Ulusal Fizyoloji Kongresi, 2014
12. Sözlü sunum- Kilic U, Gok O, Karakas M, Elibol B, Beker MC, Caglayan AB, Kilic E “İskemi sonrası fonksiyonel iyileşmeyi sağlayan plastisiteye bağlı moleküler mekanizmalarda melatoninin etkinliğinin araştırılması” 40. Ulusal Fizyoloji Kongresi, 2014.
13. Sözlü sunum- Kelestemur T, Caglayan AB, Beker MC, Yilmaz B, Kilic E “Sıçanlarda memantin ve melatonin tedavisinin travmatik beyin hasarı sonrası etkilerinin araştırılması” 11. Ulusal Sinirbilim Kongresi, 2013.
14. Poster- Caglayan AB, Beker MC, Kilic E, Kilic U “P2X7 reseptörlerinin fare optik kesisi ve fokal iskemi modelleriyle oluşturulan nöronal hasar üzerine etkisi” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
15. Poster- Kilic U, Caglayan AB, Beker MC, Kilic E “Fosfatidil inozitol-3 kinaz/AKT sinyal yolağının Melatoninin iskemi sonrası nöroprotektif etkisinde rolü” 13. Ulusal Tıbbi biyoloji ve Genetik Kongresi, 2013.
16. Sözlü sunum- Seker FB, Kilic U, Caglayan AB, Ekimci N, Cevreli B, Beker MC, Demirci S, Dogan A, Yilmaz B, Kilic E “Profiklaktik olarak uygulanan 3-Hidroksi-3-Metilglutaril Koenzim A Redüktaz İnhibitörlerinin penisilinle indüklenen beyin epileptik aktivitesine etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.
17. Sözlü-sunum- Kilic U, Caglayan B, Ethemoglu, Caglayan AB, Beker MC, Ekimci N, Kilic E “3-Hydroxy-Methykgkutaryl Coenzyme A reductase inhibitörü rosuvastatinin beyin felci sonrası beyin plastisitesi ve onarım üzerine olan etkileri” TFBD 38. Ulusal Fizyoloji Kongresi, 2012.

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Adı Soyadı Dr.Öğr.Üye. Ayşe Arzu ŞAKUL
E-Posta aasakul@medipol.edu.tr
Detay Öz Geçmiş
Medya

Ondokuzmayıs Üniversitesi 1994 Hacettepe Üniversitesi Tıp Fakültesi & Gazi Üniversitesi Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

Sağlık Bakanlığı-Acil Sağlık Hizmetleri Genel Müdürlüğü- Afet ve Acil Durum Daire Başkanlığı- Ulusal Zehir Merkezi Koordinatörü

Araştırma Alanları

Diabetes Mellitus, oksidatif ve nitrozatif stres, senescence ve rejenerasyon, bağımlılık farmakolojisi, klinik toksikoloji, klinik farmakoloji, nörofarmakoloji

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Dr.Öğr.Üye. Berrak ÇAĞLAYAN
E-Posta bcaglayan@medipol.edu.tr
Detay Öz Geçmiş
Medya

Boğaziçi Üniversitesi 2005 Yeditepe Üniversitesi

Daha Önce Görev Yaptığı Yerler

Yeditepe Üniversitesi

Araştırma Alanları

Moleküler Sinirbilim, Proteostasis, ER Stresi Projeler: TUBITAK 1001 projesi "Myeolid Türevli Büyüme Faktörü'nün Spinal Kord Hasarı Sonrası İyileşme Sürecindeki Rolü" Proje Yürütücüsü (2017-2020) TUBITAK 1002 projesi "Nogo-A'nın Stres Koşulları Altında Agrezom ile İlişkisinin İncelenmesi" Proje Yürütücüsü (2014-2015)

Seçili Yayınları / Tüm Yayınları

1. Caglayan B, Caglayan AB, Beker MC, Yalcin E, Beker M, Kelestemur T, Sertel E, Ozturk G, Kilic U, Sahin F, Kilic E. (2017) Exp Neurol "Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice"

2. Beker MC, Caglayan B, Yalcin E, Caglayan AB, Turkseven S, Gurel B, Kelestemur T, Sertel E, Sahin Z, Kutlu S, Kilic U, Baykal AT, Kilic E. (2017) Mol Neurobiol "Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT"

3. Kilic U, Caglayan AB, Beker MC, Gunal MY, Caglayan B, Yalcin E, Kelestemur T, Gundogdu RZ, Yulug B, Yilmaz B, Kerman BE, Kilic E. (2017) Redox Biol "Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice"

4. Kelestemur T, Yulug B, Caglayan AB, Beker MC, Kilic U, Caglayan B, Yalcin E, Gundogdu RZ, Kilic E. (2015) Neuroscience Letters "Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine"

5. Beker MC, Caglayan AB, Kelestemur T, Caglayan B, Yalcin E, Yulug B, Kilic U, Hermann DM, Kilic E. (2015) Oncotarget "Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation"

6. Eren Z, Günal MY, Bakir EA, Coban J, Çağlayan B, Ekimci N, Ethemoglu S, Albayrak O, Akdeniz T, Demirel GY, Kiliç E, Kantarci G. (2014) Kidney Blood Press Res "Effects of Paricalcitol and Aliskiren Combination Therapy on Experimental Diabetic Nephropathy Model in Rats"

7. Seker FB, Kilic U, Ekimci N, Ethemoglu MS, Caglayan B, Demirci S, Dogan A, Oztezcan S, Sahin F, Yılmaz B, Kilic E. (2014) Neurosci "HMG-CoA reductase inhibition ameliorates brain epileptiform activity, improves blood-brain barrier integrity and effects gene expression profiling: Role of eNOS and cerebral hemodynamic"

8. Seker FB, Yorulmaz H, Kaptan E, Caglayan B, Oztas B. (2014) Nutr Neurosci "Gestational Treatment of Folic Acid Improves Blood-Brain Barrier Permeability in Pregnant- and Prepubertal rats after Pentylenetetrazole-Induced Seizure"

9. Kandemir B, Caglayan B, Hausott B, Erdogan B, Dag U, Demir O, Savasan Sogut M, Klimaschewski L, Aksan Kurnaz I. (2014) Frontiers Mol Neuroscience "PEA3 transcription factor promotes neurite outgrowth"

10. Sahin K, Tuzcu M, Basak N, Caglayan B, Kilic U, Sahin F, Kucuk O. (2012) J Oncol "Sensitization of Cervical Cancer Cells to Cisplatin by Genistein: The Role of NF?B and Akt/mTOR Signalling Pathways"

11. Berk B, Us D, Öktem S, Kocagöz ZT, Caglayan B, Aksan Kurnaz I, Demir Erol D. (2011) Turk. J. Chem "Molecular modelling and antimycobacterial studies of Mannich bases: 5-hydroxy-2-methyl-4H-pyran-4-ones"

12. Us D, Berk B, Gurdal E, Aytekin N, Kocagoz T, Caglayan B, Aksan Kurnaz I, Demir Erol D. (2010) Turk. J. Chem "Mannich base derivatives of 3-hydroxy-6- methyl-4H-pyran-4-one with antimicrobial activity"

13. Us D, Gurdal E, Berk B, Oktem S, Kocagoz T, Caglayan B, Aksan Kurnaz I, Demir Erol D. (2009) Turk. J. Chem "4H-Pyran-4-one derivatives:; leading molecule for preparation of compounds with antimycobacterial potential"

14. Akgün H, Berk B, Demir Erol D, Mercanoğlı G, Bayrak ÖF, Caglayan B, Dedeağac A and Aksan Kurnaz I. (2008) Turk J Chem "Nitric Oxide Releasing Derivatives of [(2-Chloroethyl)ureido] Benzoic Acid Esters as Potential Antineoplastic Agents"


Diğer:
1. Caglayan B, Caglayan AB, Beker MC, Kilic U, Yalcin E, Altunay S, Kelestemur T, Gunal MY, Hanoglu L, Yulug B, Kilic E (2016). "Repetitive transcranial magnetic stimulation promotes neuronal survival in the acute phase and stroke-recovery in the sub-acute phase of focal cerebral ischemia" EMBO Meeting, Mannheim, Germany

2. Caglayan AB, Beker MC, Kilic U, Caglayan B, Kelestemur T, Gundogdu RZ, Kilic E (2013). “Roles of P2X7 receptors in neuronal injury after optic nerve transaction and focal cerebral ischemia in mice” EMBO Meeting, Amsterdam, the Netherlands

3. Kilic U, Caglayan B, Ethemoglu MS, Caglayan AB, Beker MC, Ekimci N, Kilic E (2012). “3-Hydroxy-3-methylglutaryl coenzyme a reductase inhibitörü rosuvastatinin beyin felci sonrası beyin plastisitesi ve onarımı üzerine olan etkileri” 38. Ulusal Fizyoloji Kongresi, Trabzon

4. Çağlayan B, Aksan Kurnaz, I (2011). “Identification of Phosphorylation Sites of Pea3 Transcription Factor” 10. Ulusal Sinirbilim Kongresi, İstanbul

5. Çağlayan B, Dedeağaç A, Aksan Kurnaz, I (2008). “Bölge hedefli mutajenez ile Pea3 transkripsiyon faktörünün fosforilasyon bölgelerinin tanımlanması”, poster presentation, VII. Ulusal Sinirbilimleri Kongresi, Adana

6. Çağlayan B, Demir O, Oney P, Aksan Kurnaz I. (2007). “Sinir farklılaşmasında PEA3 proteininin etki mekanizması”. VI. Ulusal Sinirbilimleri Kongresi, Safranbolu

7. Caglayan B, Dedeagac A, Bayrak Ö F, Sahin F, Aksan Kurnaz I (2007) “The anti-proliferative effects of various drug candidates on neuroblastoma cells” poster presentation, 5th ISPC


Ödüller:
10. Ulusal Sinirbilim Kongresi "Identification of Phosphorylation Sites of Pea3 Transcription Factor" posteri ile en iyi üçüncü poster ödülü (2011)

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Adı Soyadı Dr.Öğr.Üye. Deniz DURALI
E-Posta ddurali@medipol.edu.tr
Detay Öz Geçmiş
Medya

1995 İmmünoloji/Université Paris Descartes

Daha Önce Görev Yaptığı Yerler

INSERM (Institut national de la santé et de la recherche médicale / Fransa) DETAE (İstanbul Üniversitesi Deneysel Tıp Araştırma Enstitüsü / Türkiye) TÜBİTAK-MAM (Türkiye Bilimsel ve Teknolojik Araştırma Kurumu - Marmara Araştırma Merkezi / Türkiye) İstanbul Medipol Üniversitesi (Türkiye)

Araştırma Alanları

İmmün regülasyon İmmün hafıza Hücresel immünite Anti-viral immünite İnflamasyon Aşı

Seçili Yayınları / Tüm Yayınları

de Goër de Herve MG, Abdoh M, Jaafoura S, Durali D, Taoufik Y. Follicular CD4 T Cells Tutor CD8 Early Memory Precursors: An Initiatory Journey to the Frontier of B Cell Territory. iScience. 2019 Sep 14;20:100-109. doi: 10.1016/j.isci.2019.09.012.

Durali D., de Goer de Herve MG., Gasnault J., Taoufik Y. : B cells and progressive multifocal leukoencephalopathy: search for the missing link. Front. Immunol. 6 (241) : 1-9, 2015

de Goër de Herve MG, Durali D, Dembele B, Giuliani M, Tran TA, Azzarone B, Eid P, Tardieu M, Delfraissy JF, Taoufik Y. Interferon-alpha triggers B cell effector 1 (Be1) commitment. PLoS One. 2011 Apr 29;6(4):e19366.

de Goer de Herve MG, Durali D, Tran TA, Maigne G, Simonetta F, Leclerc P, Delfraissy JF, Taoufik Y. Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40. Blood. 2005 Oct 15;106(8):2806-14.

Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y. In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood. 2003 Dec 1;102(12):4084-9.

Gasnault J, Kahraman M, de Goer de Herve MG, Durali D, Delfraissy JF, Taoufik Y. Critical role of JC virus-specific CD4 T-cell responses in preventing progressive multifocal leukoencephalopathy. AIDS. 2003 Jul 4;17(10):1443-9

Durali D, Morvan J, Letourneur F, Schmitt D, Guegan N, Dalod M, Saragosti S, Sicard D, Levy JP, Gomard E. Cross-reactions between the cytotoxic T-lymphocyte responses of human immunodeficiency virus-infected African and European patients. J Virol. 1998 May;72(5):3547-53.

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Adı Soyadı Dr.Öğr.Üye. Özlem GÜVEN
E-Posta oguven@medipol.edu.tr
Detay Öz Geçmiş
Medya

Ankara Üniversitesi 2003 İstanbul Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Viroloji, mikrobiyal moleküler biyoloji

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Dr.Öğr.Üye. Nihal KARAKAŞ
E-Posta nkarakas@medipol.edu.tr
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi Deneysel Tıp Araştırma Enstitüsü ve Harvard Tıp Fakültesi, Massachusetts General Hospital

Daha Önce Görev Yaptığı Yerler

Molecular Neurotherapy and Imaging Laboratory (MNIL), Massachusetts General Hospital, Harvard Medical School ve University of Edinburgh, Center for Regenerative Medicine, Adult Cell Therapy Group

Araştırma Alanları

In cancer therapy, toxicity in healthy tissue is a common side effect of current treatment modalities and tumor recurrence is almost inevitable. There is therefore an urgent need to develop novel therapies that act in a robust and cancer-selective manner. In line with this, main focus of our research is developing novel targeting therapy approaches for cancer treatment. One of the succesfull delivery strategy for targeted therapeutics without the limitations of current chemotherapeutic agents, is using stem cells as therapeutic cargo carriers since they have known with their migration capacity towards the tumor sites even including microdeposits. Furthermore, stem cells can be collected individually and engineered to secrete therapeutics which can enable their clinical translation from bench side to bed side. Recently, we are working on engineering stem cells to secrete anti-cancer therapeutics including targeted toxins for the treatment of high grade gliomas and other malignancies. For this aim, we combine bioimaging markers (fluorescence proteins and firefly luciferases) and therapeutic molecules in stem cells using lentiviral vectors. Following pre- and post-implantation of these therapeutically engineered stem cell cargos in mice bearing bioimagable tumors, we then analyse tumor regression by fluorescence/bioluminescence imaging tools and subsequent tissue processing. Furthermore, we investigate the molecular mechanism leading to cancer cell death in culture and to loss in tumor mass in treated mice upon therapeutic stem cell implantation. We study in a close collaboration with Dr. Shah who is the head of Center for Stem Cell Therapeutics and Imaging, Brigham and Woman's Hospital, Harvard Medical School in Boston, U.S. Selected media attentions: - Cancer-killing stem cells engineered in lab (BBC News, October 24, 2014) - Stem cells that can kill cancer have been engineered by scientists (The Independent, October 27, 2014) - Toxin-Secreting Stem Cells May Destroy Brain Tumors From Inside Out (Popular Science, October 27, 2014)

Seçili Yayınları / Tüm Yayınları

• Stuckey DW*, Hingtgen S*, Karakas N, Rich B, Shah K. “Engineering toxin-resistant therapeutic
stem cells to treat brain tumors”, Stem Cells, (Oct. 2014) *authors equally contributed.
• Karakas N, Stuckey DW, Choi SH, Shah K. “ Arming stem cells with targeted toxins breaks
resistance and potentiates TRAIL killing of brain tumors” (in submission)
• Karakas N, Shah K. “Stem Cell Delivery of Targeted Toxins for GBM Therapy (Review)” (in
preperation)
• Isik S, Zaim M, Yildiz MT, Negis Y, Kunduraci T, Karakas N, Arikan G, Cetin G. “DNA
topoisomerase IIß as a molecular switch in neural differentiation of mesenchymal stem cells”,
Annals of Hematology, Sept. 2014
• Mammadov B, Karakas N, Isik S. "Comparison of Long-term Retinoic Acid Based Neural Induction
Methods of Bone Marrow Human Mesenchymal Stem Cells", In vitro Cellular & Developmental
Biology , May 2011
• Kamaci N, Emnacar T, Karakas N, Arikan G, Tsutsui K, Isik. "Selective silencing of DNA
topoisomerase IIß in human mesenchymal stem cells by small interfering RNAs (siRNAs)", Cell
Biology International Reports, March 2011
• Karakas N, Mammadov B, Isik S, "Involvement of Integrin ?5ß1 in Neural Transdifferentiation of
Human Bone Marrow Derived Mesenchymal Stem Cells " (Abstract), Journal of IUBMB Life, May.
2009
• Mammadov B, Karakas N, Isik S, "Emphasis of the Efficient In Vitro Neurogenesis Method For
Bone Marrow Derived Human Mesenchymal Stem Cells" (Abstract), Journal of IUBMB Life, May
2009


Selected media attentions:
- Cancer-killing stem cells engineered in lab (BBC News, October 24, 2014)
- Stem cells that can kill cancer have been engineered by scientists (The Independent, October 27, 2014)
- Toxin-Secreting Stem Cells May Destroy Brain Tumors From Inside Out (Popular Science, October 27, 2014)

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Adı Soyadı Dr.Öğr.Üye. Elif Zeynep YILMAZ
E-Posta ezyilmaz@medipol.edu.tr
Detay Öz Geçmiş
Medya

İstanbul Üniversitesi 1997 İstanbul Üniversitesi Onkoloji Enstitüsü Kanser Biyokimyası

Daha Önce Görev Yaptığı Yerler

İstanbul Üniversitesi Onkoloji Enstitüsü

Araştırma Alanları

Moleküler Onkoloji, Meme Kanseri, Kolorektal Kanser ve Löseminin Moleküler Biyolojisi

Seçili Yayınları / Tüm Yayınları

ULUSLARARASI YAYINLAR
1- Eralp Y, Keskin S, Akışık E, Akışık E, İğci A, Müslümanoğlu M, Yılmaz S, Tunacı M, Çamlıca H, Tuzlalı S, Saip P, Dalay N, Özmen V, Topuz E.
Predictive role of midtreatment changes in survivin, GSTP1, and topoisomerase 2? expressions for pathologic complete response to neoadjuvant chemotherapy in patients with locally advanced breast cancer.
Am J Clin Oncol. 2013 Jun;36(3):215-23.

2- Akisik E, Buğra D, Yamaner S, Dalay N.
Analysis of ß-catenin alterations in colon tumors: a novel exon 3 mutation.
Tumour Biol. 2011; 32(1):71-6.

3- Akisik E., Yazici H, Dalay N.
ARLTS1, MDM2 and RAD51 gene variations are associated with familial breast cancer. Mol Biol Rep. 2011; 38(1):343-8.

4 - Yazici H, Zipprich J, Peng T, Akisik E.Z, Tigli H, Isin M, Akisik EE, Terry MB, Senie RT, Li L, Peng M, Liu Z, Dalay N and Santella RM.
Investigation of the miR16-1 (C>T)+7 substitution in six different types of cancer from three ethnic groups.
J Oncol. 2009; 2009: 1-4.

5- Deligezer U, Eralp Y, Akisik EZ, Akisik EE, Saip P, Topuz E, Dalay N.
Effect of adjuvant chemotherapy on integrity of free serum DNA in patients with breast cancer.
Ann N Y Acad Sci. 2008; 1137: 175-9.

6 - Deligezer U, Eralp Y, Akisik EE, Akisik EZ, Saip P, Topuz E, Dalay N.
Size distribution of circulating cell-free DNA in sera of breast cancer patients in the course of adjuvant chemotherapy.
Clin Chem Lab Med. 2008; 46 (3): 311-7.

7 - Akisik E, Dalay N.
Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer.
J Clin Lab Anal 2007; 21:97–102.

8 - Akisik E, Dalay N.
Estrogen receptor codon 594 and HER2 codon 655 polymorphisms and breast cancer risk.
Exp Mol Pathol 2004; 76 (3): 260-263.

9 - Akisik E, Bavbek S, Dalay N.
CD44 variant exons in leukemia and lymphoma
Pathol Oncol Res 2002; 8; 1: 36-40.

10 - Yazici H, Bitisik O, Akisik E, Cabioglu N, Saip P, Muslumanoglu M, Glendon G, Bengisu E, Ozbilen S, Dincer M, Turkmen S, Andrulis IL, Dalay N, Ozcelik H.
BRCA1 and BRCA2 mutations in Turkish breast/ovarian families and young breast cancer patients.
Br J Cancer 2000; 83 (6): 737-742.

ULUSAL YAYINLAR
1 - Elif Zeynep Akışık, Nejat Dalay.
Kolon, Rektum ve Anal Kanserlerin Moleküler Biyolojisi.
Klinik Laboratuvar Cilt 3, Sayı-1-2, Ocak-Haziran 2004, 1-9.

KİTAP BÖLÜMLERİ
1- Ugur Deligezer, Elif Z. Akisik, Ebru E. Akisik, Müge Kovancilar, Dursun Bugra, Nilgün Erten, Stefan Holdenrieder, Nejat Dalay. İçinde Peter B. Gahan, editör. Circulating Nucleic Acids in Plasma and Serum. Dordrecht Heidelberg London New York Springer., 2011. pp. 97-103.

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Adı Soyadı Dr.Öğr.Üye. Cüneyd PARLAYAN
E-Posta cparlayan@medipol.edu.tr
Detay Öz Geçmiş
Medya

Toronto Universitesi 2008 Tokyo Medical and Dental University

Daha Önce Görev Yaptığı Yerler

Ulasal kanser Arastirma Merkezi, Tokyo/Japonya

Araştırma Alanları

Kanser epidemiologisi ve genetigi, Kanserde OMICS uygulamalari ve analizi, Kisilestirilmis tip

Seçili Yayınları / Tüm Yayınları

1. Parlayan C, Ikeda S, Sato N, Sawabe M, Muramatsu M, Arai M (2014) Association analysis of single nucleotide polymorphisms in miR-146a and miR-196a2 on the prevalence of cancer in elderly Japanese population: a case–control study. Asian Pac J Cancer Prev, 15 (5), 2101-2107.
2. Tani Y*, Parlayan C*, Takai Y, Kawai A, Unuma Y, Kinoshita H, Kondo T. Evaluation of narrow range IPG gels in a novel automated two-dimensional gel electrophoresis machine, Auto2D. Electrophoresis Letters Vol.59 (2015) No.1, p.9-12. (*: Equal contribution)
3. Parlayan C, Asano N, Yoshida A, Kawai A, Kondo T. (2014) Current status of global expression profiling of sarcoma; meta-analysis for clinical applications. Cancer Research (under review)

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Adı Soyadı Dr.Öğr.Üye. Sultan Sibel ERDEM
E-Posta serdem@medipol.edu.tr
Detay Öz Geçmiş
Medya

Marmara Universitesi 2001 Louisiana State Universitesi

Daha Önce Görev Yaptığı Yerler

Harvard Tip Fakultesi ve Massachusetts Genel Hastanesi

Araştırma Alanları

Hedefe yönelik ilaçlar ve nanopartikul ilaç sistemleri, kanserin fotodinamik terapi ile tedavisi, cesitli hastaliklarin teshis ve tedavisinde kullanilanilan biomarker hedefli floresan sistemler, isikla aktive olan moleküllerin tasarim ve sentezi.

Seçili Yayınları / Tüm Yayınları

Erdem, Sibel S. Near-IR Dyes and Their Use in Medical Sciences" MUSBED, 2016, in press

Hara, T., Ughi, G.J., McCarthy, J.M Erdem, Sibel S., Mauskapf, A., Lyon, S.S, Fard, A, M., Edelman, E.E., Tearney, G. J., and Jaffer, F. A. “Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo” European Heart Journal, in press

Stein-Merlo, Kessinger, C. W., Erdem, Sibel S, Zelada, H., Hilderbrand, S.H., Lin, C. P., J.G Tearney, J.G., Jaff, M. R., Reed, G.R., Henke, P.K., McCarthy, J.M., Farouc A. Jaffer, F.A. Blood “Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study” Theranostics, 2015; 5(12): 1317-1327

Erdem, Sibel S.; Konishi, Masanori.; Weissleder, Ralph.; Lichtman, Andrew H.; McCarthy, Jason, R.; Libby, Peter. “Imaging granzyme B activity assesses immune mediated myocarditis.” Circulation Research, 2015, 117(6), 502-512.

Erdem, Sibel S.; Khan, Shazia, Palanasami, Akilan and Hasan, Tayyaba. “Rapid, Low-cost Fluorescent Assay of Beta-Lactamase Derived Antibiotic Resistance and Related Antibiotic Susceptibility, Journal of Biomedical Optics, 2014, 19, 10, 105007.

Avci, Pinar; Erdem, Sibel S.; Hamblin, Michael R. “Photodynamic Therapy: One Step Ahead with Self-Assembled Nanoparticles” Journal of Biomedical Nanotechnology, 2014, 10, 1–16.

Spring, Q. Bryan; Abu-Yousif, O. Adnan.; Palanisami, Akilan.; Zheng, Xiang.; Anbil,
Sriram; Sears, R. Bryan; Mensah, B. Lawrence; Goldschmidt, Ruth; Erdem, Sibel S;Oliva, Esther; Hasan, Tayyaba. “Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function activatable immunoconjugates” Proceeding of National Academia of Science U.S.A ., 2014, 11, 10, E933-E942.

Erdem, Sibel S; Fronczek, Frank R.; Watkins, Steven F. “Bis[2,3,4-trimethyl-5-[(3,4,5-trimethyl-2H-pyrrol-2-yl-idene-? N)meth-yl]-1H-pyrrolato-? N]copper(II)” Acta Crystallogr. Sect E Struct. Rep. Online. 2012, 68 (11), 1335-1336.

McCarthy, Jason R.; Sazonova, Irina Y.; Erdem, Sibel S.; Hara, Tetsuya.; Thompson, Brian D.; Patel, Purvish.; Botnaru, Ion.; Lin, Charles P.; Reed, Guy L.; Weissleder, Ralph and Jaffer, Farouc A. “Multifunctional Nanoagent for Thrombus-targeted Fibrinolytic Therapy” Nanomedicine , 2012,7, 1017-1028.

Nesterova, Irina V.; Bennett CA.; Erdem, Sibel S.; Hammer, Robert P.; Deininger PL. and Soper, Steven A. “Near-IR single fluorophore quenching system based on phthalocyanine (Pc) aggregation and its application for monitoring inhibitor/activator action on a therapeutic target: L1-EN” Analyst , 2011, 136, 1103-1105.

McCarthy, Jason R.; Bhaumik, Jayeeta; Karver, Mark R.; Erdem, S. Sibel.; Bardon,
Kevin.; and Weissleder, Ralph. “Targeted Nanoagents for the Detection of Cancers” Molecular Oncology, 2010, 4, 511-528.

Erdem, Sibel S.; Nesterova, Irina V.; Soper, Steven A. and Hammer, Robert P. “Monoamine Functionalized Phthalocyanines: Microwave-Assisted Solid-Phase Synthesis and Bioconjugation Strategies” The Journal of Organic Chemistry , 2009, 74, 9280-9286.

Nesterova, Irina V.; Erdem, Sibel S.; Pakhomov, Serhii.; Hammer, Robert P. and Soper, Steven A. “Phthalocyanine Dimerization-Based Molecular Beacons Using Near-IR Fluorescence” The Journal of American Chemical Society , 2009, 131, 2432-2433.

Erdem, Sibel S.; Nesterova, Irina V.; Soper, Steven A. and Hammer, Robert P. “Solid- Phase Synthesis of Asymmetrically Substituted “AB3 ” Type Phthalocyanines”, The Journal of Organic Chemistry , 2008, 73, 5003-5007.

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Adı Soyadı Dr.Öğr.Üye. ŞULE AYLA
E-Posta sayla@medipol.edu.tr
Detay Öz Geçmiş
Medya

Uludağ Üniversitesi 1998 İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi

Daha Önce Görev Yaptığı Yerler

Şanlıurfa Kadın Doğum Hastanesi Süleymaniye Kadın Doğum Hastanesi Zeynep Kamil Kadın Hastalıkları ve Doğum Eğitim ve Araştırma Hastanesi

Araştırma Alanları

Kanser, Kanser kök hücre, Infertilite, In vitro fertilizasyon, Sperm DNA hasarı, Hücre kültürü, tekrarlayan düşükler, immünohistokimya, elektron mikroskobu

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Dr.Öğr.Üye. Serhat SEYHAN
E-Posta sseyhan@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Dr.Öğr.Üye. Akif AYAZ
E-Posta aayaz@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

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Adı Soyadı Dr.Öğr.Üye. Salih GENCER
E-Posta sgencer@medipol.edu.tr
Detay Öz Geçmiş
Medya

Daha Önce Görev Yaptığı Yerler

Araştırma Alanları

Seçili Yayınları / Tüm Yayınları

Kurum Dışı Görevlendirme

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Adı Soyadı Prof.Dr. Ülkan KILIÇ
E-Posta ukilic@medipol.edu.tr
Detay Öz Geçmiş
Medya

Ankara Üniversitesi 1994 1. Doktora: Ludwig-Maximilians University (LMU), Moleküler Biyoloji ve Mikrobiyoloji 2. Doktora: Bern Graduate School, Hücresel ve Biyomedikal Bilimler

Daha Önce Görev Yaptığı Yerler

Brain Research Laboratory, Department of Neurology, Medical School, University of Tübingen, Germany Brain Research Laboratory, Department of Neurology, Medical School, University of Göttingen, Germany Brain Research Laboratory, Department of Neurology, Medical School, University of Zürich, Switzerland Cardiovascular Research, Institute of Physiology, University of Zürich, Switzerland Yeditepe Üniversitesi Tıp Fakültesi Tıbbi Biyoloji A.D. Bezmialem Vakıf Üniversitesi Tıp Fakültesi Tıbbi Biyoloji A. D. Bşk.

Araştırma Alanları

Nörodejenerasyon, Kardiyovaskuler Hastalıklar, Metabolik Sendrom, Epidemiyoloji

Seçili Yayınları / Tüm Yayınları

Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities) 1. Kilic U, Gok O, Erenberk U, Dundaroz ME, Torun E, Kucukardali Y, Elibol-Can B, Uysal O, Dundar T. A remarkable age-related increase in SIRT1 protein expression against to oxidative stress in elderly: SIRT1 gene variants and longevity in human. PLoS One 2015 Mar 18;10(3):e0117954 (IF:3.534) 2. Kilic U, Gok O, Elibol-Can B, Uysal O, Bacaksiz A. Efficacy of statins on sirtuin 1 and endothelial nitric oxide synthase expression: The role of sirtuin 1 gene variants in human coronary atherosclerosis. Clin Exp Pharmacol Physiol. 2015 Jan 13. doi: 10.1111/1440-1681.12362. ( IF:2.4) 3. Kilic U., Sahin K., Tuzcu M., Basak N., Orhan C., Elibol-Can B., Kilic E., Sahin F., Kucuk O. Enhancement of cisplatin sensitivity in human cervical cancer: epigallocatechin-3-gallate. Frontiers in NUTRITION: 26 January 2015 doi: 10.3389/fnut.2014.00028 4. Venkatanarayana Gangarapu, Ali Tüzün Ince, Birol Baysal, Yusuf Kayar, Ulkan Kılıç, Özlem Gok, Ömer Uysal, Hakan Şenturk. Efficacy of rifaximin on circulating endotoxins and cytokines in patients with non-alcoholic fatty liver. European Journal of Gastroenterology & Hepatology 2015, Jul;27(7):840-5. doi: 10.1097/MEG.0000000000000348. ( IF:2.15) 5. Erkoc R, Cikrikcioglu MA, Aintab E, Erek Toprak A, Kilic U, Gok O, Yasin Cetin AI, Zorlu M, Kiskac M, Cakirca M, Erkal SN, Isen HC, Karatoprak C. GAS6 intron 8 c.834?+?7G?>?A gene polymorphism in diabetic nephropathy. Ren Fail. 2015 Apr 14:1-5. ( IF:0,775) 6. Gok O, Karaali ZE, Acar L, Kilic U, Ergen A. ABCG5 and ABCG8 Gene Polymorphisms in Type 2 Diabetes Mellitus in the Turkish Population. Can J Diabetes. 2015 Jun 16. pii: S1499-2671(15)00394-9. doi: 10.1016/j.jcjd.2015.04.004( IF:0,46) 7. Kilic U, Gok O, Bacaksiz A, Izmirli M, Elibol-Can B, Uysal O. SIRT1 gene polymorphisms affect the protein expression in cardiovascular diseases. PLoS One. 2014 Feb 8;9(2):e90428. doi: 10.1371/journal.pone.0090428. eCollection 2014. (IF:3.534) 8. Kilic U., Gok O., Elibol-Can B., Ozgen IT., Erenberk U., Uysal O., Dundaroz MR. “SIRT1 gene variants are related to risk of childhood obesity” Eur J Pediatr. 2014 Sep 20. (IF: 1.983) 9. Aysan E, Kilic U, Gok O, Altug B, Ercan C, Idiz UO, Kesgin C, Muslumanoglu M. A novel non-surgical, minimally invasive technique for parathyroid autotransplantation: A case report. Pediatr Transplant. 2015 Mar;19(2):E37-40. doi: 10.1111/petr.12410. Epub 2014 Dec 13. (IF: 1.63) 10. Aysan E, Kilic U, Gok O, Altug B, Ercan C, Kesgin Toka C, Idiz UO, Muslumanoglu M. Parathyroid Allotransplant for Persistent Hypocalcaemia: A New Technique Involving Short-Term Culture. Exp Clin Transplant. 2014 Dec 3. doi: 10.6002/ect.2014.0110. [Epub ahead of print] (IF: 0.80) 11. Kilic E, Reitmeir R, Kilic U, Caglayan AB, Beker MC, Kelestemur T, Ethemoglu MS, Ozturk G and Hermann DM(2014) HMG-CoA reductase inhibition promotes neurological recovery, perilesional tissue remodeling and contralesional pyramidal tract plasticityafter focal cerebral ischemia. Front. Cell. Neurosci. 8:422. doi:10.3389/fncel.2014 (IF: 4.2) 12. Fatma B. Seker, Ulkan Kilic, Nur Ekimci, Signem Ethemoglu, Berrak Caglayan, Selami Demirci, Aysegül Dogan, Serdar Öztezcan, Fikrettin Sahin, Bayram Yilmaz, Ertugrul Kilic. HMG-CoA reductase inhibition ameleriotes brain epileptiform activity: Role of eNOS Neuroscience. 2014 Oct 19;284C:349-359. doi: 10.1016/j.neuroscience.2014.10.014. (IF: 3.5) 13. Ceber M, Mihmanli A, Kilic U, Sener U, Yuksek A, Durak MA, Tulubas F. Changes in expression of Slit1 and its receptor Robo2 in trigeminal ganglion and inferior alveolar nerve following inferior alveolar nerve axotomy in adult rats: a pilot study. Int J Oral Maxillofac Surg. 2014 Nov 11. pii: S0901-5027(14)00383-X. doi: 10.1016/j.ijom.2014.09.022. (IF: 1.788) 14. Torun E, Gedik AH, Cakir E, Umutoglu T, Gok O, Kilic U. Serum paraoxonase 1 activity and oxidative stress in pediatric patients with pulmonary tuberculosis. Med Princ Pract. 2014;23(5):426-31. doi: 10.1159/000363700. Epub 2014 Jul 16. (IF: 1.113) 15. Müzeyyen İzmirli, Ömer Göktekin, Ahmet Bacaksız, Ömer Uysal, Ülkan Kılıç (Corresponding author and group leader). The effect of the SIRT1 2827 A>G polymorphism, resveratrol, exercise, age and occupation in Turkish population with cardiovascular disease. The Anatolian Journal of Cardiology 2014 DOI: 10.5152/akd.2014.5214 ( IF:0.715) 16. Erenberk U, Dundaroz R, Gok O, Uysal O, Agus S, Yuksel A, Yilmaz B, Kilic U. (Corresponding author and group leader)Melatonin attenuates phenytoin sodium-induced DNA damage. Drug Chem Toxicol. 2014 Apr;37(2):233-9. doi: 10.3109/01480545.2013.838777. ( IF:1.3) 17. Erhan Aysan, Ufuk Oguz Idiz; Deniz Firat; Fikrettin Sahin; Selami Demirci; Ulkan Kilic; Ozlem Gok; Mahmut Muslumanoglu. Effects of boric acid-linked ampicillin on the rat intra-abdominal sepsis model. Submitted to Journal of Trace Elements in Medicine and Biology 2014 18. Mehmet Çeber, Umit Sener; Ahmet Mihmanli; Ulkan Kilic; Birol Topcu; Merve Karakas. Relationship between changes in expression of growth associated protein-43 and functional recovery of injured inferior alveolar nerve following axotomy without repair in adult rats submitted to International Journal of Oral & Maxillofacial Surgery 19. Kilic U, Yilmaz B, Reiter RJ, Yüksel A, Kilic E. Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice. Neuroscience. 2013 May 1;237:268-76. doi: 10.1016/j ( IF:3.458) 20. Kilic U, Kilic E, Tuzcu Z, Tuzcu M, Ozercan IH, Yilmaz O, Sahin F, Sahin K. Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond). 2013 Jan 12;10(1):7. doi: 10.1186/1743-7075-10-7. ( IF:2.89) 21. Kilic U, Yilmaz B, Ugur M, Yüksel A, Reiter RJ, Hermann DM, Kilic E. Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia. J Pineal Res. 2012 Mar;52(2):228-35. ( IF:5.855) 22. Sahin K, Tuzcu M, Basak N, Caglayan B, Kilic U, Sahin F, Kucuk O. Sensitization of Cervical Cancer Cells to Cisplatin by Genistein: The Role of NF?B and Akt/mTOR Signaling Pathways. J. Oncol. 2012;2012:461562. doi: 10.1155/2012/461562. Epub 2012 Sep 27. 23. Herz J, Reitmeir R, Hagen SI, Reinboth BS, Guo Z, Zechariah A, ElAli A, Doeppner TR, Bacigaluppi M, Pluchino S, Kilic U, Kilic E, Hermann DM. Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. Neurobiol Dis. 2012 Mar;45(3):1077-85. ( IF:5.121) 24. Reitmeir R, Kilic E, Reinboth BS, Guo Z, ElAli A, Zechariah A, Kilic U, Hermann DM. Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta Neuropathol. 2012 Feb;123(2):273-84. ( IF:7.695) 25. Reitmeir R, Kilic E, Kilic U, Bacigaluppi M, ElAli A, Salani G, Pluchino S , Max Gassmann M Hermann DM. Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain 134(1): 84-99 2011 (I.F.:9.490) 26. Kilic U, Tug N, Karateke A, Yılmaz B, Uğur M, Kilic E. Erytropoietin receptor-like immunostaining on human spermatozoa. Reprod Biomed Online. Jun 19 2010 (I.F.: 2.380) (All of the authors equally contributed to this work.) 27. Kilic E, Elali A, Kilic U, Guo Z, Ugur M, Uslu U, Bassetti CL, Schwab ME, Hermann DM. Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab. Jan 20 2010 (I.F.: 5.741) 28. Tug N, Altunkaynak ME, Aktas RG, Kilic U, Yilmaz B, Cam C, Karateke A. Does erythropoietin affect motility of spermatozoa? Arch Gynecol Obstet. 2010 May; 281(5):933-8 (I.F.: 1.072) 29. Bacigaluppi M, Pluchino S, Jametti LP, Kilic E, Kilic U, Salani G, Brambilla E, West MJ, Comi G, Martino G, Hermann DM. Delayed post-ischemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain. Aug;132(Pt 8):2239-51, 2009 (I.F.: 9.603) 30. Osto E, Matter CM, Kouroedov A, Malinski T, Bachschmid M, Camici GG, Kilic U, Stallmach T, Boren J, Iliceto S, Lüscher TF, Cosentino F .c-Jun N-Terminal Kinase 2 Deficiency Protects Against Hypercholesterolemia-Induced Endothelial Dysfunction and Oxidative Stress. Circulation. Nov 11;118 (20):2073-80. Oct 27. 2008 (I.F.: 14.595) 31. Kilic E, Spudich A, Kilic U, Rentsch KM, Vig R, Matter CM, Wunderli-Allenspach H, Fritschy JM, Bassetti CL, Hermann DM. ABCC1: a gateway for pharmacological compounds to the ischaemic brain. Brain. Oct;131 (Pt 10):2679-89. 2008 (I.F.: 9.603) 32. Kilic U, Kilic E, Bassetti CL, Hermann DM. TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration. Neurobiology Dis. Jul; 31(1):33-40. 2008 (I.F.: 4.852) 33. Hédou GF, Koshibu K, Farinelli M, Kilic E, Gee CE, Kilic U, Baumgartel K. Hermann DM, Mansuy IM.. PP1-dependent bidirectional synaptic plasticity controls ischemic recovery in the adult brain, Journal of Neuroscience Jan 2; 28(1):154-62. 2008 (I.F.: 7.452) 34. Kilic E, Kilic U, Bacigallupi M. Guo Z, Ben Abdallah N, Reiter RJ, Wolfer DP. Hermann DM, Bassetti CL. Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pin Res Sep;45(2):142-8. 2008 (I.F.: 5.056) 35. Kilic E, Kilic U, Vogel P, Böttiger B, Hermann DM. Poxvirus-derived cytokine response modifier a (crma) does not protect against focal cerebral ischemia in mice. Brain Res. 1185: 293-300. 2007 (I.F.: 2.494) 36. Kilic U, Kilic E, Järve A, Guo Z, Spudich A, Bieber K, Barzena U, Bassetti CL, Marti HH, Hermann DM. Human VEGF protects axotomized retinal ganglion cells in vivo by activating ERK-1/-2 and Akt pathways Journal of Neuroscience 26 (48):12439-46 2006 (I.F.: 7.452) 37. Kilic E, Kilic U, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/ Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J. Jun 20: 81185-7 2006 (I.F.: 7.049) 38. Matter CM, Ma L, von Lukowicz T, Meier P, Lohmann C, Zhang D, Kilic U, Hofmann E, Ha SW, Hersberger M, Hermann DM, Lüscher TF. Increased balloon-induced inflammation, proliferation, and neointima formation in apolipoprotein E (ApoE) knockout mice. Stroke. Oct; 37(10):2625-32. 2006 (I.F.: 6.499) 39. Spudich A, Kilic E, Xing H, Kilic U, Wunderli-Allenspach H, Bassetti CL, Hermann DM. Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia. Nature Neuroscience 9: 487-488 2006 (I.F.: 14.164) 40. Kilic E, Kilic U, and Hermann DM TAT fusion proteins against ischemic stroke: Current status and future perspectives. Frontiers in Bioscience 11:1716-1721. 2006 (I.F.: 3.308) 41. Kilic, E, Kilic U, Bähr M and Hermann, D.M.´´NMDA Antagonist MK-801 Reverses detrimental Effects of Tissue-Plasminogen Activator Following Intraluminal Thread Occlusion in Mice. Neurodegenerative diseases 2: 49-55 2005 (I.F.: 2.989) 42. Kilic E, Kilic U, Soliz U, Gassmann M, Bassetti CL, Hermann DM. Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J 19:2026-2028. 2005 (I.F.: 7.049) 43. Kilic U, Kilic E, Soliz J, Gassmann M, Bassetti CL, Hermann DM. Erythropoietin-induced neuroprotection following retinal ganglion cell axotomy is mediated by ERK-1/-2 signaling in vivo FASEB J 19: 249-251. 2005 (I.F.: 7.049) 44. Kilic U, Kilic E, Reiter RJ, Bassetti CL, Hermann DM. Signal transduction pathways mediating melatonin-induced neuroprotection after focal cerebral ischemia in mice. Journal of Pineal Research Jan; 38(1):67-71. 2005 (I.F.: 5.056) 45. Kilic E, Kilic U, Reiter RJ, Bassetti CL, Hermann DM. Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt. Journal of Pineal Research 39; 151-156. 2005 (I.F.: 5.056) 46. Wang Y, Kilic E, Kilic U, Weber B, Bassetti CL, Marti HH and Hermann DM. Brain-selective VEGF overexpression induces post-ischemic neuroprotection, but also facilitates hemodynamic steal phenomena. Brain. Jan; 128(1) 52-63. 2005 (I.F.: 9.603) 47. Kilic U, Kilic E, Bassetti CL and Hermann DM. Post-ischemic delivery of rosuvastatin induces neuroprotection after intraluminal thread occlusion in mice via Erk-1/-2, Bcl-XL and caspases-9/ -3, but not endothelial NO synthetase (eNOS) pathways. Neuroscience. 134:901-906. 2005 (I.F.: 3.556) 48. Kilic E, Kilic U, Matter C, Lüscher TF, Bassetti CL and Hermann DM. Inhibition of endothelial NO synthase by tissue-plasminogen activator after focal cerebral ischemia: Signaling mechanisms and reversal by statin. Stroke Feb;36(2):332-6. 2005 (I.F.: 6.499) 49. Spudich A, Frigg R, Kilic E, Kilic U, Bassetti CL, Hermann DM. Aggravation of brain injury by prion protein deficiency, but lack of neuroprotection by enhanced prion protein expression following focal cerebral ischemia in mice: Role of STAT-1 and JNK-1/-2 Neurobiology of Disease Nov; 20(2): 442-9. 2005 (I.F.: 4.852) 50. Kilic E, Kilic U, and Hermann DM. TAT-GDNF in neurodegeneration and ischemic stroke. CNS Drug Reviews 11:353-362. 2005 (I.F.: 4.432) 51. Reiter RJ, Tan DX, Leon J, Kilic U, Kilic E. When melatonin gets on your nerves: Its benefical actions in experimental models of stroke. Experimental Biology and Medicine Feb; 230(2):104-17. 2005 (I.F.: 2.202) 52. Grimm, C., Hermann, D.M., Bogdanova, A., Hotop, S., Kilic, Ü., Wenzel, A., Kilic, E., and Gassmann, M. Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration. Sem. Cell Dev. Biol. 16: 531-538. 2005 (I.F.: 4.528) 53. Kilic U, Kilic E, Dietz GPH and Bähr M. The TAT protein transduction domain enhances the neuroprotective effect of Glial Cell Line-Derived Neurotrophic Factor after Optic Nerve Transection in Mice. Neurodegenerative Diseases 1, 144-49. 2004 (I.F.: 2.989) 54. Kilic U, Yulug B, Kilic E and Bähr M. Rifampicin attenuates brain damage in focal ischemia. (Equal contribution), Brain Research 996: 76-80. 2004 (I.F.: 2.494) 55. Kilic U, Kilic E, Lingor P, Yulug B and Bähr M. Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after MPP+-intoxication in vitro Acta Neuropathologica 108, 65-68. 2004 (I.F.: 5.310) 56. Kilic E, Kilic U, Reiter RJ, Bassetti CL, Hermann DM. Prophylactic use of melatonin protects against focal cerebral ischemia in mice: role of endothelin converting enzyme-1. Journal of Pineal Research. Nov; 37(4):247-51. 2004 (I.F.: 5.056) 57. Kilic E, Weishaupt JH, Kilic U, Rohde G, Yulug B, Peters K, Hermann DM and, Bahr M. The superoxid dismutase 1 (sod1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice. Neuroscience 128 (2), 359-364. 2004 (I.F.: 3.556) 58. Kilic E, Kilic U, Hermann DM, Yulug B and Reiter RJ Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator Journal of Pineal Research 36, 171-176. 2004 (I.F.: 5.056) 59. Kilic E, Kilic U, Bassetti CL, and Hermann DM. Intravenously administrated recombinant tissue-plasminogen activator attenuates neuronal injury after mild focal ischemia. Neuroreport 15:687-689. 2004 60. Reiter RJ, Tan DX, Gitto E, Sainz RM, Mayo JC, Leon J, Manchester LC, Vijayalaxmi, Kilic E, Kilic U. Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. Polish Journal of Pharmacology Mar-Apr; 56 (2): 159-70. 2004 (I.F.: 2.167, The Pharmacological Reports) 61. Kilic, U, Kilic E, Dietz GPH and Bähr M. Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice´´. Stroke 34, 1304-1310. 2003 (I.F.: 1.64) 62. Kilic U, Schalch B, Stolle A. Ribotyping of Clostridium perfringens from industrially produced ground meat. Letters of Applied Microbiology 34(4) 238-243. 2002 63. Kilic E, DM Hermann, S Kügler, H., Kilic U, Schmeer, C., Holzmüller and M. Bähr. `Adenovirus-mediated neuron-specific Bcl-XL expression protects against disseminated neuronal injury and brain infarction following transient middle cerebral artery occlusion in mice. Neurobiology of Disease 11:275-284. 2002 (I.F.: 4.852) 64. Kilic U, Schalch B, Solle A. Zur Feintypisierung von Clostridium perfringens aus rohem Fleisch. Archiv für Lebensmittelhygiene 52:13-15. 2001