Course Description
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| BIOPHYSICS | - | Yearly | 22+0 | - | 2 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assist.Prof. Nazlı EZER ÖZER |
| Name of Lecturer(s) | Assist.Prof. Nazlı EZER ÖZER |
| Assistant(s) | |
| Aim | The primary aim of this course is to elucidate the fundamental concepts and methodologies of biophysics in a straightforward and comprehensible manner. This course includes an introduction to biophysics, its subject matter, scope, and subfields. It covers physical quantities, the International System of Units (SI), and dimensional analysis. The structure and function of biological and model membranes are explored, along with mechanisms of substance transport across biological membranes. The course also addresses the composition and distribution of body fluids, the roles of major physiological ions, the generation of resting and action membrane potentials, and provides an introduction to radiation biophysics and electrophysiological techniques. Additionally, the biophysics of skeletal, smooth, and cardiac muscles is examined, with particular focus on the generation of action potentials and muscle contraction mechanisms. Finally, the physical principles and practical applications of electromyography EMG) are discussed. |
| Course Content | This course contains; Introduction to Biophysics ,Biological and Model Membranes,Membrane Transport Systems,Body Fluids, The Ions in the Body,Resting Membrane Potential & Action Potential,Introduction to Radiation Biophysics,Introduction to Electrophysiological Techniques (ECG, EEG, EMG),Biophysics of Skeletal Muscle, Action Potential in Skeletal Muscle, Skeletal Muscle Contraction Mechanism ,Biophysics of Smooth Muscle, Action Potential in Smooth Muscle, Smooth Muscle Contraction Mechanism ,Biophysics of Cardiac Muscle, Action Potential in Cardiac Muscle, Cardiac Muscle Contraction Mechanism ,Physical Principles of EMG. |
| Course Learning Outcomes | Teaching Methods | Assessment Methods |
| 1. Understands the definition, scope, and subfields of biophysics, and recognises its interdisciplinary connections with other scientific disciplines. Gains knowledge of physical quantities, the SI unit system, dimensional analysis, and appreciates the importance of standardisation in scientific practice. | 10, 14, 16, 9 | |
| 2. Learns the molecular organisation of biological membranes and comprehends their significance for sustaining life. Understands the structure and function of model membranes, which closely resemble biological membranes, and grasps their potential applications in scientific research. | 10, 14, 16, 9 | |
| 3. Acquires knowledge about the mechanisms of substance transport across biological membranes, a fundamental process essential for maintaining cellular functions. | 10, 14, 16, 9 | |
| 4. Identifies the compartments of body fluids and the major ions present in the human body and explains their physiological functions. | 10, 14, 16, 9 | |
| 5. Learns the processes involved in the generation of resting membrane potential and action potential in excitable cells. | 10, 14, 16, 9 | |
| 6. Defines the types of ionising and non-ionising radiation, radioactivity, radiation dose units, types of detectors, and the basic principles of radiation protection. | 10, 14, 16, 9 | |
| 7. Understands the types, basic physical principles, and clinical and research applications of electrophysiological techniques. | 10, 14, 16, 9 | |
| 8. Comprehends the biophysical properties of skeletal, smooth, and cardiac muscle tissues, and describes the generation of action potentials and contraction mechanisms in these muscle types. | 10, 14, 16, 9 | |
| 9. Gains knowledge of EMG recording technique and its applications; understands the principles of neural and muscular communication. | 10, 14, 16, 9 |
| Teaching Methods: | 10: Discussion Method, 14: Self Study Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to Biophysics | Reading the lecture notes provided before the class |
| 2 | Biological and Model Membranes | Reading the lecture notes provided before the class |
| 3 | Membrane Transport Systems | Reading the lecture notes provided before the class |
| 4 | Body Fluids, The Ions in the Body | Reading the lecture notes provided before the class |
| 5 | Resting Membrane Potential & Action Potential | Reading the lecture notes provided before the class |
| 6 | Introduction to Radiation Biophysics | Reading the lecture notes provided before the class |
| 7 | Introduction to Electrophysiological Techniques (ECG, EEG, EMG) | Reading the lecture notes provided before the class |
| 8 | Biophysics of Skeletal Muscle, Action Potential in Skeletal Muscle, Skeletal Muscle Contraction Mechanism | Reading the lecture notes provided before the class |
| 9 | Biophysics of Smooth Muscle, Action Potential in Smooth Muscle, Smooth Muscle Contraction Mechanism | Reading the lecture notes provided before the class |
| 10 | Biophysics of Cardiac Muscle, Action Potential in Cardiac Muscle, Cardiac Muscle Contraction Mechanism | Reading the lecture notes provided before the class |
| 11 | Physical Principles of EMG | Reading the lecture notes provided before the class |
| Resources |
| Lecture notes will be provided to students prior to each class. Biyofizik, Prof. Dr. Ferit Pehlivan; 9th Edition, Pelikan Yayıncılık, 2017, Ankara; Biophysics: Text Book, Prof. Dr. Mehmet Can Akyolcu, Cerrahpaşa Faculty of Medicine Publication No: 295, 2015, İstanbul; Biophysics: An Introduction, Roland Glaser, Springer, 2012. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | X | |||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | X | |||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | X | |||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | X | |||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | X | |||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | X | |||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | X | |||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | X | |||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | X | |||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | X | |||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | X | |||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | X | |||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | X | |||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | X | |||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 11 | 2 | 22 | |||
| Guided Problem Solving | 2 | 2 | 4 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 2 | 4 | 8 | |||
| General Exam | 2 | 4 | 8 | |||
| Performance Task, Maintenance Plan | 2 | 2 | 4 | |||
| Total Workload(Hour) | 46 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(46/30) | 2 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| BIOPHYSICS | - | Yearly | 22+0 | - | 2 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Assist.Prof. Nazlı EZER ÖZER |
| Name of Lecturer(s) | Assist.Prof. Nazlı EZER ÖZER |
| Assistant(s) | |
| Aim | The primary aim of this course is to elucidate the fundamental concepts and methodologies of biophysics in a straightforward and comprehensible manner. This course includes an introduction to biophysics, its subject matter, scope, and subfields. It covers physical quantities, the International System of Units (SI), and dimensional analysis. The structure and function of biological and model membranes are explored, along with mechanisms of substance transport across biological membranes. The course also addresses the composition and distribution of body fluids, the roles of major physiological ions, the generation of resting and action membrane potentials, and provides an introduction to radiation biophysics and electrophysiological techniques. Additionally, the biophysics of skeletal, smooth, and cardiac muscles is examined, with particular focus on the generation of action potentials and muscle contraction mechanisms. Finally, the physical principles and practical applications of electromyography EMG) are discussed. |
| Course Content | This course contains; Introduction to Biophysics ,Biological and Model Membranes,Membrane Transport Systems,Body Fluids, The Ions in the Body,Resting Membrane Potential & Action Potential,Introduction to Radiation Biophysics,Introduction to Electrophysiological Techniques (ECG, EEG, EMG),Biophysics of Skeletal Muscle, Action Potential in Skeletal Muscle, Skeletal Muscle Contraction Mechanism ,Biophysics of Smooth Muscle, Action Potential in Smooth Muscle, Smooth Muscle Contraction Mechanism ,Biophysics of Cardiac Muscle, Action Potential in Cardiac Muscle, Cardiac Muscle Contraction Mechanism ,Physical Principles of EMG. |
| Course Learning Outcomes | Teaching Methods | Assessment Methods |
| 1. Understands the definition, scope, and subfields of biophysics, and recognises its interdisciplinary connections with other scientific disciplines. Gains knowledge of physical quantities, the SI unit system, dimensional analysis, and appreciates the importance of standardisation in scientific practice. | 10, 14, 16, 9 | |
| 2. Learns the molecular organisation of biological membranes and comprehends their significance for sustaining life. Understands the structure and function of model membranes, which closely resemble biological membranes, and grasps their potential applications in scientific research. | 10, 14, 16, 9 | |
| 3. Acquires knowledge about the mechanisms of substance transport across biological membranes, a fundamental process essential for maintaining cellular functions. | 10, 14, 16, 9 | |
| 4. Identifies the compartments of body fluids and the major ions present in the human body and explains their physiological functions. | 10, 14, 16, 9 | |
| 5. Learns the processes involved in the generation of resting membrane potential and action potential in excitable cells. | 10, 14, 16, 9 | |
| 6. Defines the types of ionising and non-ionising radiation, radioactivity, radiation dose units, types of detectors, and the basic principles of radiation protection. | 10, 14, 16, 9 | |
| 7. Understands the types, basic physical principles, and clinical and research applications of electrophysiological techniques. | 10, 14, 16, 9 | |
| 8. Comprehends the biophysical properties of skeletal, smooth, and cardiac muscle tissues, and describes the generation of action potentials and contraction mechanisms in these muscle types. | 10, 14, 16, 9 | |
| 9. Gains knowledge of EMG recording technique and its applications; understands the principles of neural and muscular communication. | 10, 14, 16, 9 |
| Teaching Methods: | 10: Discussion Method, 14: Self Study Method, 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Introduction to Biophysics | Reading the lecture notes provided before the class |
| 2 | Biological and Model Membranes | Reading the lecture notes provided before the class |
| 3 | Membrane Transport Systems | Reading the lecture notes provided before the class |
| 4 | Body Fluids, The Ions in the Body | Reading the lecture notes provided before the class |
| 5 | Resting Membrane Potential & Action Potential | Reading the lecture notes provided before the class |
| 6 | Introduction to Radiation Biophysics | Reading the lecture notes provided before the class |
| 7 | Introduction to Electrophysiological Techniques (ECG, EEG, EMG) | Reading the lecture notes provided before the class |
| 8 | Biophysics of Skeletal Muscle, Action Potential in Skeletal Muscle, Skeletal Muscle Contraction Mechanism | Reading the lecture notes provided before the class |
| 9 | Biophysics of Smooth Muscle, Action Potential in Smooth Muscle, Smooth Muscle Contraction Mechanism | Reading the lecture notes provided before the class |
| 10 | Biophysics of Cardiac Muscle, Action Potential in Cardiac Muscle, Cardiac Muscle Contraction Mechanism | Reading the lecture notes provided before the class |
| 11 | Physical Principles of EMG | Reading the lecture notes provided before the class |
| Resources |
| Lecture notes will be provided to students prior to each class. Biyofizik, Prof. Dr. Ferit Pehlivan; 9th Edition, Pelikan Yayıncılık, 2017, Ankara; Biophysics: Text Book, Prof. Dr. Mehmet Can Akyolcu, Cerrahpaşa Faculty of Medicine Publication No: 295, 2015, İstanbul; Biophysics: An Introduction, Roland Glaser, Springer, 2012. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ1: Knows the morphological and functional normal and abnormal structure of human body. | X | |||||
| 2 | PQ2: Knows the essential ways of determining the underlying causes of the pathologies with basic scientific approaches and the diagnoses of illnesses and disorders. | X | |||||
| 3 | PQ3: Knows the reasons for illnesses, the ways of protection, and the methods of promotion and improvement of public health. | X | |||||
| 4 | PQ4: Knows the methods of advancing his/her knowledge about health and its practice. | X | |||||
| 5 | PQ5: Accesses, interprets and applies the advanced interdisciplinary information related to health. | X | |||||
| 6 | PQ6: Performs a complete clinical examination of the human body, both morphologically and functionally and defines the problems. | ||||||
| 7 | PQ7: Interprets examination data for diagnoses, compares with clinical data, and provides solutions. | ||||||
| 8 | PQ8: Selects and applies appropriate tools for promotion and improvement of individual and public health. | X | |||||
| 9 | PQ9: Plans and conducts an advanced study of health independently. | X | |||||
| 10 | PQ10: Takes responsibility individually and as a team member to solve the problems encountered in the promotion and improvement of individual and public health. | X | |||||
| 11 | PQ11: Takes responsibility for any intervention on the human body for the diagnosis and treatment. | ||||||
| 12 | PQ12: Determines personal learning requirements and decides and develops a positive lifelong learning attitude. | X | |||||
| 13 | PQ13: Evaluates the information gained in the field of health with a critical approach. | X | |||||
| 14 | PQ14: Informs the patient, the relevant people and institutions, and the public about the health problem and conveys recommendations of solutions in writing and/or verbally. | ||||||
| 15 | PQ15: Shares their recommendations on promotion and improvement of health with interdisciplinary experts by supporting with data. | X | |||||
| 16 | PQ16: Uses English at least at the General Level of European Language Portfolio B1, follows resources in his/her field and communicates. | X | |||||
| 17 | PQ17: Uses computer software, information, and communication technologies at least at the Advanced Level of European Computer Operating License. | ||||||
| 18 | PQ18: Acts in accordance with social, scientific, cultural and ethical values in the stages of obtaining, interpreting, applying and announcing the data related to the field of health. | X | |||||
| 19 | PQ19: Develops strategy, policy and implementation plans on health issues and evaluate the results obtained the framework of quality processes. | ||||||
| 20 | PQ20: Systematically shares his/her works on promoting and improving health with quantitative and qualitative data and interdisciplinary experts. | X | |||||
| 21 | PQ21: Has sufficient awareness on occupational health and safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |