It is aimed to strengthen the basic biochemistry knowledge of 2 nd year students in this course, which is going to be taken in Spring. We will start the course by focusing on the structure and properties of water which is one of the important molecules that form organisms. The acid/base character of amino acids along with the structure, function, and purification methods of proteins will also be studied. This will be followed by considering the structure and function of enzyme as well as their regulation. Subsequently, the mechanism of a enzyme-ligand complex will be focused on the basis of allostery and cooperatively phenomena. Finally, some selected hot topics in the field of biochemistry will be discussed interactively with the students.
Course Content
This course contains; Molecular Interactions in a Biological Context Introduction to Biochemistry,Overview of Energy and Metabolism,Carbohydrates,Glycogen Metabolism,Glycolysis,Citric Acid Cycle,Electron Transfer Chain and Oxidative Phosphorylation,Enzyme Reactions,Lipids,Lipid Metabolism,Amino Acids,Protein Structure,Fibrous Proteins,Globular Proteins.
Course Learning Outcomes
Teaching Methods
Assessment Methods
Explains the basic structures, biochemical properties, and biological functions of carbohydrates, lipids, amino acids, and proteins.
Defines and relates the major metabolic pathways, including glycolysis, glycogen metabolism, the pentose phosphate pathway, the citric acid cycle, oxidative phosphorylation, gluconeogenesis, and basic lipid metabolism.
Interprets the fundamental biochemical principles related to enzymes, protein structure–function relationships, and buffer systems.
Relates cellular energy production, biomolecular transformation, and metabolic regulation to biomedical engineering applications.
Evaluates and interprets data obtained from basic biochemistry laboratory applications such as spectrophotometric measurement, glucose assay, total lipid analysis, and serum protein determination, report.
Teaching Methods:
Assessment Methods:
Course Outline
Order
Subjects
Preliminary Work
1
Molecular Interactions in a Biological Context Introduction to Biochemistry
Going through course materials
2
Overview of Energy and Metabolism
Going through course materials
3
Carbohydrates
Going through course materials
4
Glycogen Metabolism
Going through course materials
5
Glycolysis
Going through course materials
6
Citric Acid Cycle
Going through course materials
7
Electron Transfer Chain and Oxidative Phosphorylation
Going through course materials
8
Enzyme Reactions
Going through course materials
9
Lipids
Going through course materials
10
Lipid Metabolism
Going through course materials
11
Amino Acids
Going through course materials
12
Protein Structure
Going through course materials
13
Fibrous Proteins
Going through course materials
14
Globular Proteins
Going through course materials
Resources
Principles of Biochemistry - 5 th edition - Laurence A. Moran & Robert A. Horton 2. Biochemistry - 8 th edition- Mary K. Campbell & Shawn O. Farrell.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
10
A knowledge of contemporary issues
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
Assessment Methods
Contribution Level
Absolute Evaluation
Rate of Midterm Exam to Success
30
Rate of Final Exam to Success
70
Total
100
ECTS / Workload Table
Activities
Number of
Duration(Hour)
Total Workload(Hour)
Course Hours
14
4
56
Guided Problem Solving
14
4
56
Resolution of Homework Problems and Submission as a Report
4
5
20
Term Project
0
0
0
Presentation of Project / Seminar
0
0
0
Quiz
0
0
0
Midterm Exam
1
20
20
General Exam
1
30
30
Performance Task, Maintenance Plan
0
0
0
Total Workload(Hour)
182
Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(182/30)
6
ECTS of the course: 30 hours of work is counted as 1 ECTS credit.
Detail Informations of the Course
Course Description
Course
Code
Semester
T+P (Hour)
Credit
ECTS
BIOCHEMISTRY
BME2221320
Spring Semester
3+2
4
6
Course Program
Prerequisites Courses
Recommended Elective Courses
Language of Course
English
Course Level
First Cycle (Bachelor's Degree)
Course Type
Required
Course Coordinator
Assoc.Prof. Özge ŞENSOY
Name of Lecturer(s)
Res.Assist. Birgün ÖZÇOLAK ASLAN
Assistant(s)
Aim
It is aimed to strengthen the basic biochemistry knowledge of 2 nd year students in this course, which is going to be taken in Spring. We will start the course by focusing on the structure and properties of water which is one of the important molecules that form organisms. The acid/base character of amino acids along with the structure, function, and purification methods of proteins will also be studied. This will be followed by considering the structure and function of enzyme as well as their regulation. Subsequently, the mechanism of a enzyme-ligand complex will be focused on the basis of allostery and cooperatively phenomena. Finally, some selected hot topics in the field of biochemistry will be discussed interactively with the students.
Course Content
This course contains; Molecular Interactions in a Biological Context Introduction to Biochemistry,Overview of Energy and Metabolism,Carbohydrates,Glycogen Metabolism,Glycolysis,Citric Acid Cycle,Electron Transfer Chain and Oxidative Phosphorylation,Enzyme Reactions,Lipids,Lipid Metabolism,Amino Acids,Protein Structure,Fibrous Proteins,Globular Proteins.
Course Learning Outcomes
Teaching Methods
Assessment Methods
Explains the basic structures, biochemical properties, and biological functions of carbohydrates, lipids, amino acids, and proteins.
Defines and relates the major metabolic pathways, including glycolysis, glycogen metabolism, the pentose phosphate pathway, the citric acid cycle, oxidative phosphorylation, gluconeogenesis, and basic lipid metabolism.
Interprets the fundamental biochemical principles related to enzymes, protein structure–function relationships, and buffer systems.
Relates cellular energy production, biomolecular transformation, and metabolic regulation to biomedical engineering applications.
Evaluates and interprets data obtained from basic biochemistry laboratory applications such as spectrophotometric measurement, glucose assay, total lipid analysis, and serum protein determination, report.
Teaching Methods:
Assessment Methods:
Course Outline
Order
Subjects
Preliminary Work
1
Molecular Interactions in a Biological Context Introduction to Biochemistry
Going through course materials
2
Overview of Energy and Metabolism
Going through course materials
3
Carbohydrates
Going through course materials
4
Glycogen Metabolism
Going through course materials
5
Glycolysis
Going through course materials
6
Citric Acid Cycle
Going through course materials
7
Electron Transfer Chain and Oxidative Phosphorylation
Going through course materials
8
Enzyme Reactions
Going through course materials
9
Lipids
Going through course materials
10
Lipid Metabolism
Going through course materials
11
Amino Acids
Going through course materials
12
Protein Structure
Going through course materials
13
Fibrous Proteins
Going through course materials
14
Globular Proteins
Going through course materials
Resources
Principles of Biochemistry - 5 th edition - Laurence A. Moran & Robert A. Horton 2. Biochemistry - 8 th edition- Mary K. Campbell & Shawn O. Farrell.
Course Contribution to Program Qualifications
Course Contribution to Program Qualifications
No
Program Qualification
Contribution Level
1
2
3
4
5
1
An ability to apply knowledge of mathematics, science, and engineering
X
2
An ability to identify, formulate, and solve engineering problems
X
3
An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
4
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
5
An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
X
6
An ability to function on multidisciplinary teams
X
7
An ability to communicate effectively
X
8
A recognition of the need for, and an ability to engage in life-long learning
X
9
An understanding of professional and ethical responsibility
10
A knowledge of contemporary issues
11
The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
