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Doç.Dr. Barkın BERK

Barkın BERK

Eczacılık Fakültesi
Analitik Kimya Anabilim Dalı

Eczacılık Fakültesi, Hacettepe Üniversitesi (Ankara/Türkiye) 1996 yılı mezunudur. Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya ABD bünyesinde (Ankara/Türkiye) doktora çalışmalarını tamamlamıştır 2003.
Daha önce çalışma yaptığı yerler: Hacettepe Üniversitesi, Eczacılık Fakültesi (1996-2003), Yeditepe Üniversitesi, Eczacılık Fakültesi (2003-2012), NIH/NIDDK, ABD (2009-2010), Yeditepe Sağlık Hizmetleri A.Ş. (2011-2012).
İlaç ArGe, Moleküler Modelleme, GPCR, Method Geliştirme ve Validasyon araştırma alanlarıdır.

Seçili Yayınları

- B. Berk, C. Bender, E. Küpeli Akkol, E. Yeşilada; Design and Synthesis of Stable N-[2-(aryl/heteroaryl substituted)ethyl] propanamide Derivatives of (S)-Ketoprofen and (S)-Ibuprofen as Non-Ulcerogenic Anti-Inflammatory and Analgesic Agents, Acta Pharm. Sci., 54(1), 65-80 (2016)

- F.E. Onen-Bayram, K. Buran, I. Durmaz, B. Berk, R. Cetin-Atalay; 3-Propionyl-thiazolidine-4-carboxylic Acid Ethyl Esters: A Family Of Antiproliferative Thiazolidines, MedChemComm, 6(1), 90-93 (2015).

- H. Akgün, I. Karamelekoğlu, B. Berk, I. Kurnaz, G. Sarıbıyık, S. Oktem, T. Kocagöz; Synthesis And Antimycobacterial Activity Of Some Phthalimide Derivatives, Bioorganic and Medicinal Chemistry, 20(13), 4149-54 (2012).

- S. Vilar, J. Karpiak, B. Berk, S. Costanzi; In Silico Analysis Of The Binding Of Agonists And Blockers To The β2-Adrenergic Receptor, Journal of Molecular Graphics and Modeling, 29(6), 809-817 (2011).

- B. Berk, D. Us, S. Öktem, T. Kocagöz, B. Çağlayan, I. A. Kurnaz, D. D. Erol; Molecular Modeling And Antimycobacterial Studies Of Mannich Bases: 5-Hydroxy-2-Methyl-4H-Pyran-4-Ones, Turkish Journal of Chemistry, 35(2), 317-330 (2011).

- S. Vilar, G. Ferino, S. S. Phatak, B. Berk, C. N. Cavasotto, S. Costanzi; Docking-Based Virtual Screening For Ligands Of G Protein-Coupled Receptors: Not Only Crystal Structures But Also İn Silico Models, Journal of Molecular Graphics and Modeling, 29(5), 614-623 (2011).

- D. Us, B. Berk, E. Gürdal, N. Aytekin, T. Kocagöz, B. Çağlayan, I. A. Kurnaz, D. D. Erol; Mannich Base Derivatives Of 3-Hydroxy-6-Methyl-4H-Pyran-4-One With Antimicrobial Activity, Turkish Journal of Chemistry, 34, 447-456 (2010).

- H. Maruoka, M. O. Barrett, H. Ko, D. K. Tosh, A. Melman, L. E. Burianek, R. Balasubramanian, B. Berk, S. Costanzi, T. K. Harden, K. A. Jacobson; Pyrimidine Ribonucleotides with Enhanced Selectivity as P2Y6 Receptor Agonists: Novel 4-Alkyloxyimino, (S)-Methanocarba, and 5′-Triphosphate γ-Ester Modifications, Journal of Medicinal Chemistry, 53 (11), 4488-4501 (2010).

- D. Us, E. Gürdal, B. Berk, S. Öktem, T. Kocagöz, B. Çağlayan, I. A. Kurnaz, D. D. Erol; 4H-Pyran-4-one Derivatives; Leading Molecule For Preparation Of Compounds with Antimycobacterial Potential, Turkish Journal of Chemistry, 33, 803-812 (2009).

- H. Akgün, B. Berk, D. Demir Erol, G. Mercanoğlu, Ö. F. Bayrak , B. Çağlayan, A. Dedeağaç, I. A. Kurnaz; Nitric Oxide Releasing Derivatives of [(2-chloroethyl)ureido]benzoic Acid Esters As Potential Antineoplastic Agents, Turkish Journal of Chemistry, 33, 107-121 (2009).

- B. Berk, D. D. Erol, E. Kupeli, E. Yesilada; Design and Synthesis of Some (S)-2-(6-methoxy naphthalen-2-yl)-N-substituted-ethylpropanamide Derivatives as Potent Non-ulcerogenic Anti-inflammatory and Analgesic Agents, ArzneimForsch/DrugRes, 59(4), 195-201 (2009).