Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| BIOCHEMISTRY | - | Yearly | 46+12 | - | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Neslin EMEKLİ |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI |
| Assistant(s) | |
| Aim | To describe the biochemical mechanism and reactions in blood and in the cells related to cardiovascular system,nutrition metabolism, endocrine and urogenital systems |
| Course Content | This course contains; Blood Tissue Biochemistry,Hemostasis Biochemistry ,Prothrombin Time,Atherosclerosis Biochemistry,Cardiac Damage Markers,Anemia,Digestion and Absorption of Nutrients I,Digestion and Absorption of Nutrients II,Nutrition Biochemistry,Obesity and Fat Tissue Biochemistry,Diabetes Biochemistry ,Avitaminosis ,Liver Function Tests,Amylase Assay in Blood,Porphyrins and gall pigments,Change in Energy Metabolism in Cancer,Pituitary and Hypothalamus Hormones,Thyroid and Parathyroid Hormones,Adrenal Korteks Hormonları,Adrenal Medulla Hormones,Pancreatic Hormones,Gonad hormones,Pregnancy Biochemistry ,Kidney Biochemistry,Creatinine Measurement,Urology Biochemistry,Physical and Chemical Analysis of Urine,Urine Microscopy . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 2.Hemostasis stages of the endothelial cells, platelets, coagulation proteins, fibrinolytic system, including proteins and inhibitors, mechanisms of action, and the mechanisms of biochemical methods used in the diagnosis and treatment are described. and their respective mechanisms. | 16, 17, 19, 9 | A, D, E, G |
| 6.Description and absorption mechanisms of carbohydrates and proteins taken by the animals are explained. The effects of secretin and cholecystokinin which are effective on digestion, pancreatic enzymes are explained. Different amino acids formed by the breakdown of proteins into amino acids, different mechanisms of absorption systems and possible inhibitions are described. Symptoms of lactose and sucrose intolerance due to carbohydrate digestion disorder and related biochemical tests are explained. | 16, 17, 19, 9 | A, D, E, G |
| 10.The definition and types of diabetes, the factors that affect the screening tests for the diagnosis of diabetes mellitus, oral glucose tolerance test, glycosylated hemoglobin, hypoglycemia, biochemical mechanisms of hyperglycemia, electrolytes in diabetes mellitus, biochemical reactions in diabetic keto acidosis are explained. | 16, 17, 19, 9 | A, D, E, G |
| 11.Water and fat-soluble vitamins and vitamins-related substances in the needs and shortcomings of diseases, daily needs, where the pathologies and mechanisms that occur in deficiencies are explained. | 16, 17, 19, 9 | A, D, E, G |
| 12.Cell damage to the liver, cholestasis, intra and extra hepatic cholestasis, the functions of the synthesis of the liver and the synthesis of these synthesis functions are explained. Associated with diseases. | 16, 17, 19, 9 | A, D, E, G |
| 13.The reactions involved in the formation of 4 pyrrole rings that form the hemoglobin and its groups, enzymes, possible diseases due to the inhibition of enzymes, bile pigments derived from the destruction of hemoglobin, biliverdin, biluribin formation. Bilirib metabolism, direct and indirect biliribinin clinical meaning, tests, urinary and faecal changes are explained during the breakthrough. | 16, 17, 19, 9 | A, D, E, G |
| 14.Cancer cell glucose uses much more than normal cells and glucose taken turns to lactate as the main metabolic pathway. Apart from glucose use in cancer, there are differences in lipid metabolism and protein metabolism and metabolism of these differences are explained. | 16, 17, 19, 9 | A, D, E, G |
| 15.The characteristics of the hormones released from the anterior, middle and arteries of the pituitary, their mechanisms of action are structurally similar to one another, neural stimuli from the hypothalamus, release of pituitary hormones and the mechanisms of the effects of these hormones on the target cells, laboratory tests of these hormones are explained. | 16, 17, 19, 9 | A, D, E, G |
| 16.The effects of thyroid hormones on various tissues, synthesis stages, speed limiting factors in these stages, the effect of TSH, the inactivation of the synthesis steps by various chemicals, the transport of T3 and T4 to the target tissue by the carrier proteins, the differences between the carrier proteins and the inhibitions of various chemicals are explained. | 16, 17, 19, 9 | A, D, E, G |
| How to synthesize the mineralocorticoids, glycocorticoids and adrenal androgens released from the adrenal cortex, from cholesterol and from acetyl CoA to the nova synthesis in the cell, how they are transported free or depending on the protein, the disorders that are reflected in the clinic and related tests are explained. | 16, 17, 19, 9 | A, D, E, G |
| 18.Adrenal medulla hücresinde tirozinden dopamin, norepinefrin ve metilasyonla epinefrin oluşumu, katekolamin adı ile de bilinen bu hormonların akut ve kronik streslere cevabı, diğer sentez yerleri, vasküler sistem yanında karbonhidrat ve lipit metabolizmasına etkileri ve laboratuvar değerlendirilmesi anlatılır. | 16, 17, 19, 9 | A, D, E, G |
| 19.In addition to the digestive function of the pancreas, hormones like hormones such as insulin and glucagon, which affect the metabolism, the hormones secreted from the pancreas and their functions, the measurement and treatment of hormones used in diagnosis and treatment are explained. | 16, 17, 19, 9 | A, D, E, G |
| 20.The reproductive function in human beings is regulated by hormones produced by gonads, pituitary, hypothalamus, adrenal cortex and placenta. | 16, 17, 19, 9 | A, D, E, G |
| 21.The menstrual cycle, biochemical mechanisms that regulate pregnancy and postpartum, analysis used in diagnosis and treatment, tests used in laboratory diagnosis of pregnancy, chromosomal anomalies, tests used in screening neural tube defects, biochemical tests in complicated pregnancies such as preeclampsia and diabetes are explained. | 16, 17, 19, 9 | A, D, E, G |
| 1. After mentioning in general about how blood tissue is composed of plasma and blood cells, how thousands of proteins in plasma are grouped, how the desired proteins are isolated from these groups, how these proteins are defined according to their properties, how the COHN fractions used in blood transfusions have changed in current blood transfusions, recombinant DNA technologies), how to use these methods for the use of proteins as biomarkers. | 16, 17, 19, 9 | A, D, E, G |
| 3. The reactions in the biochemical development stages of atherosclerosis, a multidisciplinary disease characterized by endothelial damage, various proteins and other molecules involved in these reactions, and their importance in understanding the pathogenesis of the disease, its use in diagnosis and treatment. The relation of atherosclerosis with molecules involved in hemostasis, lipid metabolism, antioxidant systems and signaling systems is established. Relevant tests are explained. | 16, 17, 19, 9 | A, D, E, G |
| 4. After summarizing the biochemistry of cardiovascular diseases, the mechanisms of myocardial damage and its significance are explained. The use of new markers such as myoglobin, CKMB, troponins and AST, LDH, and ischemia-modified albumin as early markers of ischemia are explained. The importance of homocysteine, CRP, lipoprotein a, HDL, LDL, ApoA1 and ApoBioi, which are used as cardiovascular risk assessment tests, are explained. | 16, 17, 19, 9 | A, D, E, G |
| 5. Biochemical mechanisms that cause anemia due to the decrease of erythrocyte mass are explained. The causes of endocrine disorders, kidneys and inflammation, the mechanisms of reactions affecting genetically acquired erythrocyte production, the mechanisms of anemia caused by the effects of various chemicals or antibodies, erythrocyte indexes, hematocrit, erythrocyte count, and the issues to be considered in the measurement of hemoglobin are emphasized. Metabolic disorders related to iron metabolism, transport, storage and related tests and mechanisms are explained. | 16, 17, 19, 9 | A, D, E, G |
| 7. Digestion and absorption of lipids taken with lipids, properties of chylomicrons transported by lipoproteins, properties of apolipoproteins in molecular structure, importance of apo B 48, pathologies encountered in deficiency, pancreatic enzymes in digestive system and effects of various lipases are explained. | 16, 17, 19, 9 | A, D, E, G |
| 8. The main nutrients to be taken in the diet, the relationship between nutrition with vitamins and minerals, the properties of macro and micronutrients, digestion and absorption, metabolism and excretion, nutritional metabolic disorders, biochemical pathway absorption disorders are explained. | 16, 17, 19, 9 | A, D, E, G |
| 9. Obesity of obesity caused by increased energy is more than the energy consumed, pathological results due to increased adipose tissue, causes of acquired and inherited obesity, insulin resistance in obesity, measurement, various biochemical functions of adipocytokines are explained. | 16, 17, 19, 9 | A, D, E, G |
| 22. Biochemical reactions in nephrons, functional reactions of nephrons, reactions related to the maintenance of fluid electrolyte balance, renin, erythropoietin release, vitamin D hydroxylation are explained. | 16, 17, 19, 9 | A, D, E, G |
| 23. The blood plasma is transferred from the glomerulus of the nephrons to the Bowman capsule and changes and urine formation are observed when flowing in the tubules. Physical, chemical and microscopic analysis of urine, its importance in diagnosis and treatment. | 16, 17, 19, 9 | A, D, E, G |
| Teaching Methods: | 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Blood Tissue Biochemistry | In MEBIS, the student was informed about the subject. |
| 2 | Hemostasis Biochemistry | In MEBIS, the student was informed about the subject. |
| 3 | Prothrombin Time | In MEBIS, the student was informed about the subject. |
| 4 | Atherosclerosis Biochemistry | In MEBIS, the student was informed about the subject. |
| 5 | Cardiac Damage Markers | In MEBIS, the student was informed about the subject. |
| 6 | Anemia | In MEBIS, the student was informed about the subject. |
| 7 | Digestion and Absorption of Nutrients I | In MEBIS, the student was informed about the subject. |
| 8 | Digestion and Absorption of Nutrients II | In MEBIS, the student was informed about the subject. |
| 9 | Nutrition Biochemistry | In MEBIS, the student was informed about the subject. |
| 10 | Obesity and Fat Tissue Biochemistry | In MEBIS, the student was informed about the subject. |
| 11 | Diabetes Biochemistry | In MEBIS, the student was informed about the subject. |
| 12 | Avitaminosis | In MEBIS, the student was informed about the subject. |
| 13 | Liver Function Tests | In MEBIS, the student was informed about the subject. |
| 14 | Amylase Assay in Blood | In MEBIS, the student was informed about the subject. |
| 15 | Porphyrins and gall pigments | In MEBIS, the student was informed about the subject. |
| 16 | Change in Energy Metabolism in Cancer | In MEBIS, the student was informed about the subject. |
| 17 | Pituitary and Hypothalamus Hormones | In MEBIS, the student was informed about the subject. |
| 18 | Thyroid and Parathyroid Hormones | In MEBIS, the student was informed about the subject. |
| 19 | Adrenal Korteks Hormonları | In MEBIS, the student was informed about the subject. |
| 20 | Adrenal Medulla Hormones | In MEBIS, the student was informed about the subject. |
| 21 | Pancreatic Hormones | In MEBIS, the student was informed about the subject. |
| 22 | Gonad hormones | In MEBIS, the student was informed about the subject. |
| 23 | Pregnancy Biochemistry | In MEBIS, the student was informed about the subject. |
| 24 | Kidney Biochemistry | In MEBIS, the student was informed about the subject. |
| 25 | Creatinine Measurement | In MEBIS, the student was informed about the subject. |
| 26 | Urology Biochemistry | In MEBIS, the student was informed about the subject. |
| 27 | Physical and Chemical Analysis of Urine | In MEBIS, the student was informed about the subject. |
| 28 | Urine Microscopy | In MEBIS, the student was informed about the subject. |
| Resources |
| 1.Basic and Applied Biochemistry (Nesrin Emekli ), 2.Biochemistry (Fügen Gürdöl ve Evin Ademoğlu), 3.Biochemistry Laboratory(Türkan Yiğitbaşı,Nesrin Emekli). |
| 4.Harper's Biochemistry, 5.Lehninger Principles of Biochemistry, 6.Henry's Clinical Diagnosis and Management by Laboratory Methods. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 0 | 0 | 0 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 0 | 0 | 0 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 0 | 0 | 0 | |||
| General Exam | 0 | 0 | 0 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 0 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(0/30) | 0 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| BIOCHEMISTRY | - | Yearly | 46+12 | - | 3 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Committee Course |
| Course Coordinator | Prof.Dr. Neslin EMEKLİ |
| Name of Lecturer(s) | Prof.Dr. Neslin EMEKLİ, Prof.Dr. Türkan YİĞİTBAŞI, Assoc.Prof. Mukaddes ÇOLAKOĞULLARI |
| Assistant(s) | |
| Aim | To describe the biochemical mechanism and reactions in blood and in the cells related to cardiovascular system,nutrition metabolism, endocrine and urogenital systems |
| Course Content | This course contains; Blood Tissue Biochemistry,Hemostasis Biochemistry ,Prothrombin Time,Atherosclerosis Biochemistry,Cardiac Damage Markers,Anemia,Digestion and Absorption of Nutrients I,Digestion and Absorption of Nutrients II,Nutrition Biochemistry,Obesity and Fat Tissue Biochemistry,Diabetes Biochemistry ,Avitaminosis ,Liver Function Tests,Amylase Assay in Blood,Porphyrins and gall pigments,Change in Energy Metabolism in Cancer,Pituitary and Hypothalamus Hormones,Thyroid and Parathyroid Hormones,Adrenal Korteks Hormonları,Adrenal Medulla Hormones,Pancreatic Hormones,Gonad hormones,Pregnancy Biochemistry ,Kidney Biochemistry,Creatinine Measurement,Urology Biochemistry,Physical and Chemical Analysis of Urine,Urine Microscopy . |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 2.Hemostasis stages of the endothelial cells, platelets, coagulation proteins, fibrinolytic system, including proteins and inhibitors, mechanisms of action, and the mechanisms of biochemical methods used in the diagnosis and treatment are described. and their respective mechanisms. | 16, 17, 19, 9 | A, D, E, G |
| 6.Description and absorption mechanisms of carbohydrates and proteins taken by the animals are explained. The effects of secretin and cholecystokinin which are effective on digestion, pancreatic enzymes are explained. Different amino acids formed by the breakdown of proteins into amino acids, different mechanisms of absorption systems and possible inhibitions are described. Symptoms of lactose and sucrose intolerance due to carbohydrate digestion disorder and related biochemical tests are explained. | 16, 17, 19, 9 | A, D, E, G |
| 10.The definition and types of diabetes, the factors that affect the screening tests for the diagnosis of diabetes mellitus, oral glucose tolerance test, glycosylated hemoglobin, hypoglycemia, biochemical mechanisms of hyperglycemia, electrolytes in diabetes mellitus, biochemical reactions in diabetic keto acidosis are explained. | 16, 17, 19, 9 | A, D, E, G |
| 11.Water and fat-soluble vitamins and vitamins-related substances in the needs and shortcomings of diseases, daily needs, where the pathologies and mechanisms that occur in deficiencies are explained. | 16, 17, 19, 9 | A, D, E, G |
| 12.Cell damage to the liver, cholestasis, intra and extra hepatic cholestasis, the functions of the synthesis of the liver and the synthesis of these synthesis functions are explained. Associated with diseases. | 16, 17, 19, 9 | A, D, E, G |
| 13.The reactions involved in the formation of 4 pyrrole rings that form the hemoglobin and its groups, enzymes, possible diseases due to the inhibition of enzymes, bile pigments derived from the destruction of hemoglobin, biliverdin, biluribin formation. Bilirib metabolism, direct and indirect biliribinin clinical meaning, tests, urinary and faecal changes are explained during the breakthrough. | 16, 17, 19, 9 | A, D, E, G |
| 14.Cancer cell glucose uses much more than normal cells and glucose taken turns to lactate as the main metabolic pathway. Apart from glucose use in cancer, there are differences in lipid metabolism and protein metabolism and metabolism of these differences are explained. | 16, 17, 19, 9 | A, D, E, G |
| 15.The characteristics of the hormones released from the anterior, middle and arteries of the pituitary, their mechanisms of action are structurally similar to one another, neural stimuli from the hypothalamus, release of pituitary hormones and the mechanisms of the effects of these hormones on the target cells, laboratory tests of these hormones are explained. | 16, 17, 19, 9 | A, D, E, G |
| 16.The effects of thyroid hormones on various tissues, synthesis stages, speed limiting factors in these stages, the effect of TSH, the inactivation of the synthesis steps by various chemicals, the transport of T3 and T4 to the target tissue by the carrier proteins, the differences between the carrier proteins and the inhibitions of various chemicals are explained. | 16, 17, 19, 9 | A, D, E, G |
| How to synthesize the mineralocorticoids, glycocorticoids and adrenal androgens released from the adrenal cortex, from cholesterol and from acetyl CoA to the nova synthesis in the cell, how they are transported free or depending on the protein, the disorders that are reflected in the clinic and related tests are explained. | 16, 17, 19, 9 | A, D, E, G |
| 18.Adrenal medulla hücresinde tirozinden dopamin, norepinefrin ve metilasyonla epinefrin oluşumu, katekolamin adı ile de bilinen bu hormonların akut ve kronik streslere cevabı, diğer sentez yerleri, vasküler sistem yanında karbonhidrat ve lipit metabolizmasına etkileri ve laboratuvar değerlendirilmesi anlatılır. | 16, 17, 19, 9 | A, D, E, G |
| 19.In addition to the digestive function of the pancreas, hormones like hormones such as insulin and glucagon, which affect the metabolism, the hormones secreted from the pancreas and their functions, the measurement and treatment of hormones used in diagnosis and treatment are explained. | 16, 17, 19, 9 | A, D, E, G |
| 20.The reproductive function in human beings is regulated by hormones produced by gonads, pituitary, hypothalamus, adrenal cortex and placenta. | 16, 17, 19, 9 | A, D, E, G |
| 21.The menstrual cycle, biochemical mechanisms that regulate pregnancy and postpartum, analysis used in diagnosis and treatment, tests used in laboratory diagnosis of pregnancy, chromosomal anomalies, tests used in screening neural tube defects, biochemical tests in complicated pregnancies such as preeclampsia and diabetes are explained. | 16, 17, 19, 9 | A, D, E, G |
| 1. After mentioning in general about how blood tissue is composed of plasma and blood cells, how thousands of proteins in plasma are grouped, how the desired proteins are isolated from these groups, how these proteins are defined according to their properties, how the COHN fractions used in blood transfusions have changed in current blood transfusions, recombinant DNA technologies), how to use these methods for the use of proteins as biomarkers. | 16, 17, 19, 9 | A, D, E, G |
| 3. The reactions in the biochemical development stages of atherosclerosis, a multidisciplinary disease characterized by endothelial damage, various proteins and other molecules involved in these reactions, and their importance in understanding the pathogenesis of the disease, its use in diagnosis and treatment. The relation of atherosclerosis with molecules involved in hemostasis, lipid metabolism, antioxidant systems and signaling systems is established. Relevant tests are explained. | 16, 17, 19, 9 | A, D, E, G |
| 4. After summarizing the biochemistry of cardiovascular diseases, the mechanisms of myocardial damage and its significance are explained. The use of new markers such as myoglobin, CKMB, troponins and AST, LDH, and ischemia-modified albumin as early markers of ischemia are explained. The importance of homocysteine, CRP, lipoprotein a, HDL, LDL, ApoA1 and ApoBioi, which are used as cardiovascular risk assessment tests, are explained. | 16, 17, 19, 9 | A, D, E, G |
| 5. Biochemical mechanisms that cause anemia due to the decrease of erythrocyte mass are explained. The causes of endocrine disorders, kidneys and inflammation, the mechanisms of reactions affecting genetically acquired erythrocyte production, the mechanisms of anemia caused by the effects of various chemicals or antibodies, erythrocyte indexes, hematocrit, erythrocyte count, and the issues to be considered in the measurement of hemoglobin are emphasized. Metabolic disorders related to iron metabolism, transport, storage and related tests and mechanisms are explained. | 16, 17, 19, 9 | A, D, E, G |
| 7. Digestion and absorption of lipids taken with lipids, properties of chylomicrons transported by lipoproteins, properties of apolipoproteins in molecular structure, importance of apo B 48, pathologies encountered in deficiency, pancreatic enzymes in digestive system and effects of various lipases are explained. | 16, 17, 19, 9 | A, D, E, G |
| 8. The main nutrients to be taken in the diet, the relationship between nutrition with vitamins and minerals, the properties of macro and micronutrients, digestion and absorption, metabolism and excretion, nutritional metabolic disorders, biochemical pathway absorption disorders are explained. | 16, 17, 19, 9 | A, D, E, G |
| 9. Obesity of obesity caused by increased energy is more than the energy consumed, pathological results due to increased adipose tissue, causes of acquired and inherited obesity, insulin resistance in obesity, measurement, various biochemical functions of adipocytokines are explained. | 16, 17, 19, 9 | A, D, E, G |
| 22. Biochemical reactions in nephrons, functional reactions of nephrons, reactions related to the maintenance of fluid electrolyte balance, renin, erythropoietin release, vitamin D hydroxylation are explained. | 16, 17, 19, 9 | A, D, E, G |
| 23. The blood plasma is transferred from the glomerulus of the nephrons to the Bowman capsule and changes and urine formation are observed when flowing in the tubules. Physical, chemical and microscopic analysis of urine, its importance in diagnosis and treatment. | 16, 17, 19, 9 | A, D, E, G |
| Teaching Methods: | 16: Question - Answer Technique, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, G: Quiz |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Blood Tissue Biochemistry | In MEBIS, the student was informed about the subject. |
| 2 | Hemostasis Biochemistry | In MEBIS, the student was informed about the subject. |
| 3 | Prothrombin Time | In MEBIS, the student was informed about the subject. |
| 4 | Atherosclerosis Biochemistry | In MEBIS, the student was informed about the subject. |
| 5 | Cardiac Damage Markers | In MEBIS, the student was informed about the subject. |
| 6 | Anemia | In MEBIS, the student was informed about the subject. |
| 7 | Digestion and Absorption of Nutrients I | In MEBIS, the student was informed about the subject. |
| 8 | Digestion and Absorption of Nutrients II | In MEBIS, the student was informed about the subject. |
| 9 | Nutrition Biochemistry | In MEBIS, the student was informed about the subject. |
| 10 | Obesity and Fat Tissue Biochemistry | In MEBIS, the student was informed about the subject. |
| 11 | Diabetes Biochemistry | In MEBIS, the student was informed about the subject. |
| 12 | Avitaminosis | In MEBIS, the student was informed about the subject. |
| 13 | Liver Function Tests | In MEBIS, the student was informed about the subject. |
| 14 | Amylase Assay in Blood | In MEBIS, the student was informed about the subject. |
| 15 | Porphyrins and gall pigments | In MEBIS, the student was informed about the subject. |
| 16 | Change in Energy Metabolism in Cancer | In MEBIS, the student was informed about the subject. |
| 17 | Pituitary and Hypothalamus Hormones | In MEBIS, the student was informed about the subject. |
| 18 | Thyroid and Parathyroid Hormones | In MEBIS, the student was informed about the subject. |
| 19 | Adrenal Korteks Hormonları | In MEBIS, the student was informed about the subject. |
| 20 | Adrenal Medulla Hormones | In MEBIS, the student was informed about the subject. |
| 21 | Pancreatic Hormones | In MEBIS, the student was informed about the subject. |
| 22 | Gonad hormones | In MEBIS, the student was informed about the subject. |
| 23 | Pregnancy Biochemistry | In MEBIS, the student was informed about the subject. |
| 24 | Kidney Biochemistry | In MEBIS, the student was informed about the subject. |
| 25 | Creatinine Measurement | In MEBIS, the student was informed about the subject. |
| 26 | Urology Biochemistry | In MEBIS, the student was informed about the subject. |
| 27 | Physical and Chemical Analysis of Urine | In MEBIS, the student was informed about the subject. |
| 28 | Urine Microscopy | In MEBIS, the student was informed about the subject. |
| Resources |
| 1.Basic and Applied Biochemistry (Nesrin Emekli ), 2.Biochemistry (Fügen Gürdöl ve Evin Ademoğlu), 3.Biochemistry Laboratory(Türkan Yiğitbaşı,Nesrin Emekli). |
| 4.Harper's Biochemistry, 5.Lehninger Principles of Biochemistry, 6.Henry's Clinical Diagnosis and Management by Laboratory Methods. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Knows structural (morphological) and operational (functional) properties of the normal human (medical) and disorder (disease) states | X | |||||
| 2 | Knows diagnostic methods and treatment modalities of disorders (diseases). | X | |||||
| 3 | Knows the causes of disease conditions, ways of protection and methods of promoting and improving community health. | X | |||||
| 4 | Knows the methods of developing and applying health related knowledge at advanced level. | X | |||||
| 5 | Able to reach multidisciplinary advanced knowledge regarding health-related disciplines, interpret and apply the knowledge. | ||||||
| 6 | Performs a complete clinical examination of human body structurally and functionally and identifies problems. | ||||||
| 7 | Interprets laboratory results for diagnosis, compares with clinical data and develop solution proposals. | X | |||||
| 8 | Selects and implements appropriate tools for the promotion and development of individual and community health. | X | |||||
| 9 | Plans and conducts an advanced study on health independently. | X | |||||
| 10 | Develops new strategic approaches to solve the problems encountered in the promotion and development of individual and community health. | X | |||||
| 11 | Takes the responsibility of any type of practice when diagnosing and treating human body | ||||||
| 12 | Takes the role as a leader or a team worker when solving health related problems. | X | |||||
| 13 | Evaluates knowledge and skills regarding health with a critical approach and develops a positive attitude towards lifelong learning. | X | |||||
| 14 | Informs the patient, related people, institutions and the society about the health problems and transfers solution proposals in writing, verbally and visually using effective communication means. | X | |||||
| 15 | Critically reviews, develops and acts on changes in social relations and norms that guide such relationships. | X | |||||
| 16 | Uses English at least at the European Language Portfolio B2 Level, monitors knowledge and communicates in his field. | ||||||
| 17 | Able to use advanced computer skills and informatics and communication technologies at a level required by the field. | ||||||
| 18 | Acquires, interprets, implements and announces data related to the health and acts in accordance with social, scientific, cultural and ethical values and teaches these values. | X | |||||
| 19 | Develops strategies, policy and implementation plans in the field of health and evaluates the results obtained within the framework of quality processes. | X | |||||
| 20 | Shares studies on the promotion and development of health with interdisciplinary specialists systematically, supporting with quantitative and qualitative data. | ||||||
| 21 | Has adequate awareness on occupational health and safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |