Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| GENERAL PHARMACOLOGY | - | Fall Semester | 3+0 | 3 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Assoc.Prof. Ayşe Arzu ŞAKUL |
| Name of Lecturer(s) | Prof.Dr. Hanefi ÖZBEK, Assoc.Prof. Ayşe Arzu ŞAKUL |
| Assistant(s) | |
| Aim | The aim of this course is to teach the drug pharmacokinetics and pharmacodynamics, drug effect, factors that change drug effect, basic concepts of new drug development and licensing, and pharmacovigilance. |
| Course Content | This course contains; General definitions of pharmacology,Main features of drug action and drug administration sites,Absorption and distribution of drugs,Biotransformation and excretion of drugs,Pharmacodynamic properties of drugs,Dose-concentration and dose-effect relationship,Factors that change the effects of drugs,Drug-drug, drug-food interactions,Bioavailability and bioequivalence,Preclinical and clinical studies in new drug development,Basic principles in the registration of pharmaceutical preparations: CTD, variations, brief product information (BPI) / instruction manual (IM),Pharmacovigilance,Discussion. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explain absorption, distribution, metabolism and excretion of drugs. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the dose-concentration and dose-effect relationship of drugs. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the basic features of the drug effect | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the drug administration ways, the factors that change drug's effect and interactions. | 10, 16, 19 | A, D, E, F, H |
| Explain about bioavailability and bioequivalence. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain preclinical and clinical studies in new drug development. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the basic principles of licensing pharmaceutical preparations. | 10, 16, 19, 9 | A, D, E, F, H |
| Define the concept of pharmacovigilance. | 10, 16, 19, 9 | A, D, E, F, H |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, F: Project Task, H: Performance Task |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | General definitions of pharmacology | Preparation for the previously given lecture note. |
| 2 | Main features of drug action and drug administration sites | Preparation for the previously given lecture note. |
| 3 | Absorption and distribution of drugs | Preparation for the previously given lecture note. |
| 4 | Biotransformation and excretion of drugs | Preparation for the previously given lecture note. |
| 5 | Pharmacodynamic properties of drugs | Preparation for the previously given lecture note. |
| 6 | Dose-concentration and dose-effect relationship | Preparation for the previously given lecture note. |
| 7 | Factors that change the effects of drugs | Preparation for the previously given lecture note. |
| 8 | Drug-drug, drug-food interactions | Preparation for the previously given lecture note. |
| 9 | Bioavailability and bioequivalence | Preparation for the previously given lecture note. |
| 10 | Preclinical and clinical studies in new drug development | Preparation for the previously given lecture note. |
| 11 | Basic principles in the registration of pharmaceutical preparations: CTD, variations, brief product information (BPI) / instruction manual (IM) | Preparation for the previously given lecture note. |
| 12 | Pharmacovigilance | Preparation for the previously given lecture note. |
| 13 | Discussion | Preparation for the previously given lecture note. |
| Resources |
| 1. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, S.O. Kayaalp 2. Goodman & Gilmans The Pharmacological Basis of Therapeutics, L. L. Brunton, B. A. Chabner, B. C. Knollmann 3. Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, D. E. Golan, A. H. Tashjian Jr., E. J. Armstrong 4. Basic & Clinical Pharmacology, B.G. Katzung, S. B. Masters, A. J. Trevor 5. Rang & Dale?s Pharmacology, H. P. Rang, M. M. Dale |
| Lecture notes will be given to the students. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Has up-to-date knowledge, develops and deepens the level of expertise in the field of pharmacology based on the qualifications of the undergraduate level. | X | |||||
| 2 | Knowledge of information technology, technical equipment and equipment and devices specific to the field at the level required by the field of pharmacology. | X | |||||
| 3 | Has knowledge about statistics and uses related software effectively. | X | |||||
| 4 | Analyzes and synthesizes the information that is available in the field of pharmacology using information from different disciplines and interprets them in order to create new information. | X | |||||
| 5 | Writes the report of the research that you have done. | X | |||||
| 6 | Performs necessary examinations and solves problems and problems by using advanced technological tools and equipment and tools specific to the field at the level required by the field of pharmacology. | X | |||||
| 7 | Effective use of statistical software in pharmacology, accurate selection of statistical methods, accurate calculations and accurate interpretations. | X | |||||
| 8 | Brings solution proposals, solves problems, evaluates the results obtained, and, where necessary, requires expertise in the pharmacology field. | X | |||||
| 9 | Present a scientific article at a scientific meeting. | X | |||||
| 10 | Evaluates critical knowledge about the field of pharmacology and guides learning. It follows applications based on proof. Conduct research that will create evidence in their field of professional practice. | X | |||||
| 11 | Discuss and share the knowledge of the field of health, current developments and their own work in a systematic manner in written, oral and visual manner with the same group or outside groups. | X | |||||
| 12 | Observes social, scientific and ethical values during the collection, registration, interpretation and announcement of data related to the health field. | X | |||||
| 13 | Practice in interdisciplinary studies of knowledge and problem solving skills that are assimilated in the field of health. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 2 | 28 | |||
| Guided Problem Solving | 14 | 1 | 14 | |||
| Resolution of Homework Problems and Submission as a Report | 14 | 2 | 28 | |||
| Term Project | 3 | 5 | 15 | |||
| Presentation of Project / Seminar | 10 | 2 | 20 | |||
| Quiz | 5 | 2 | 10 | |||
| Midterm Exam | 10 | 5 | 50 | |||
| General Exam | 10 | 6 | 60 | |||
| Performance Task, Maintenance Plan | 5 | 3 | 15 | |||
| Total Workload(Hour) | 240 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(240/30) | 8 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| GENERAL PHARMACOLOGY | - | Fall Semester | 3+0 | 3 | 8 |
| Course Program |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | Turkish |
| Course Level | Second Cycle (Master's Degree) |
| Course Type | Required |
| Course Coordinator | Assoc.Prof. Ayşe Arzu ŞAKUL |
| Name of Lecturer(s) | Prof.Dr. Hanefi ÖZBEK, Assoc.Prof. Ayşe Arzu ŞAKUL |
| Assistant(s) | |
| Aim | The aim of this course is to teach the drug pharmacokinetics and pharmacodynamics, drug effect, factors that change drug effect, basic concepts of new drug development and licensing, and pharmacovigilance. |
| Course Content | This course contains; General definitions of pharmacology,Main features of drug action and drug administration sites,Absorption and distribution of drugs,Biotransformation and excretion of drugs,Pharmacodynamic properties of drugs,Dose-concentration and dose-effect relationship,Factors that change the effects of drugs,Drug-drug, drug-food interactions,Bioavailability and bioequivalence,Preclinical and clinical studies in new drug development,Basic principles in the registration of pharmaceutical preparations: CTD, variations, brief product information (BPI) / instruction manual (IM),Pharmacovigilance,Discussion. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| Explain absorption, distribution, metabolism and excretion of drugs. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the dose-concentration and dose-effect relationship of drugs. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the basic features of the drug effect | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the drug administration ways, the factors that change drug's effect and interactions. | 10, 16, 19 | A, D, E, F, H |
| Explain about bioavailability and bioequivalence. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain preclinical and clinical studies in new drug development. | 10, 16, 19, 9 | A, D, E, F, H |
| Explain the basic principles of licensing pharmaceutical preparations. | 10, 16, 19, 9 | A, D, E, F, H |
| Define the concept of pharmacovigilance. | 10, 16, 19, 9 | A, D, E, F, H |
| Teaching Methods: | 10: Discussion Method, 16: Question - Answer Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam, E: Homework, F: Project Task, H: Performance Task |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | General definitions of pharmacology | Preparation for the previously given lecture note. |
| 2 | Main features of drug action and drug administration sites | Preparation for the previously given lecture note. |
| 3 | Absorption and distribution of drugs | Preparation for the previously given lecture note. |
| 4 | Biotransformation and excretion of drugs | Preparation for the previously given lecture note. |
| 5 | Pharmacodynamic properties of drugs | Preparation for the previously given lecture note. |
| 6 | Dose-concentration and dose-effect relationship | Preparation for the previously given lecture note. |
| 7 | Factors that change the effects of drugs | Preparation for the previously given lecture note. |
| 8 | Drug-drug, drug-food interactions | Preparation for the previously given lecture note. |
| 9 | Bioavailability and bioequivalence | Preparation for the previously given lecture note. |
| 10 | Preclinical and clinical studies in new drug development | Preparation for the previously given lecture note. |
| 11 | Basic principles in the registration of pharmaceutical preparations: CTD, variations, brief product information (BPI) / instruction manual (IM) | Preparation for the previously given lecture note. |
| 12 | Pharmacovigilance | Preparation for the previously given lecture note. |
| 13 | Discussion | Preparation for the previously given lecture note. |
| Resources |
| 1. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, S.O. Kayaalp 2. Goodman & Gilmans The Pharmacological Basis of Therapeutics, L. L. Brunton, B. A. Chabner, B. C. Knollmann 3. Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, D. E. Golan, A. H. Tashjian Jr., E. J. Armstrong 4. Basic & Clinical Pharmacology, B.G. Katzung, S. B. Masters, A. J. Trevor 5. Rang & Dale?s Pharmacology, H. P. Rang, M. M. Dale |
| Lecture notes will be given to the students. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Has up-to-date knowledge, develops and deepens the level of expertise in the field of pharmacology based on the qualifications of the undergraduate level. | X | |||||
| 2 | Knowledge of information technology, technical equipment and equipment and devices specific to the field at the level required by the field of pharmacology. | X | |||||
| 3 | Has knowledge about statistics and uses related software effectively. | X | |||||
| 4 | Analyzes and synthesizes the information that is available in the field of pharmacology using information from different disciplines and interprets them in order to create new information. | X | |||||
| 5 | Writes the report of the research that you have done. | X | |||||
| 6 | Performs necessary examinations and solves problems and problems by using advanced technological tools and equipment and tools specific to the field at the level required by the field of pharmacology. | X | |||||
| 7 | Effective use of statistical software in pharmacology, accurate selection of statistical methods, accurate calculations and accurate interpretations. | X | |||||
| 8 | Brings solution proposals, solves problems, evaluates the results obtained, and, where necessary, requires expertise in the pharmacology field. | X | |||||
| 9 | Present a scientific article at a scientific meeting. | X | |||||
| 10 | Evaluates critical knowledge about the field of pharmacology and guides learning. It follows applications based on proof. Conduct research that will create evidence in their field of professional practice. | X | |||||
| 11 | Discuss and share the knowledge of the field of health, current developments and their own work in a systematic manner in written, oral and visual manner with the same group or outside groups. | X | |||||
| 12 | Observes social, scientific and ethical values during the collection, registration, interpretation and announcement of data related to the health field. | X | |||||
| 13 | Practice in interdisciplinary studies of knowledge and problem solving skills that are assimilated in the field of health. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 50 | |
| Rate of Final Exam to Success | 50 | |
| Total | 100 | |