Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL TECHNOLOGY LAB. IV | PHA4214879 | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program | ( B ) Pazartesi 13:30-14:15 ( B ) Pazartesi 14:30-15:15 ( B ) Pazartesi 15:30-16:15 ( A ) Pazartesi 10:00-10:45 ( A ) Pazartesi 11:00-11:45 ( A ) Pazartesi 12:00-12:45 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma Julide AKBUĞA |
| Name of Lecturer(s) | Prof.Dr. Fatma Julide AKBUĞA |
| Assistant(s) | |
| Aim | To be intended to enable students to have practical skills the preparations and quality controls of solid dosage forms, stability tests and reaction kinetics. |
| Course Content | This course contains; Demonstration,The preparations of cachet,The preparation of hard gelatin capsules,Wet and dry granulation,The preparation of tablet by direct compression method,The preparation of tablet by wet granulation method,The preparation of tablet by wet granulation method,The preparation of effervescent tablets,The coating of tablets by Wurster Apparatus,The preparation of dragee,The quality control of granule,The quality control of tablets,Accerelated stability test,Make-up. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the and of this course, the students; | ||
| 1. prepare powder formulations, capsule and tablet. | 10, 12, 17, 19, 9 | A, D |
| 1. will be defined powder formulations, capsule and tablet. | 10, 12, 17, 19, 9 | A, D |
| 1.2. recognize the excipients of tablet. | 10, 12, 17, 19, 9 | A, D |
| 1.3. Recognize excipients used in the preparation of solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 2. will be evaluated the coating methods of tablet-solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 2.1. interpret the devices used the coating of solid dosage forms | 10, 12, 17, 19, 9 | A, D |
| 2.2. categorize the coating of solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 3. will be assessed the quality control of the solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 3.1. interpret the controls of granule. | 10, 12, 17, 19, 9 | A, D |
| 3.2. design the quality control of tablets. | 10, 12, 17, 19, 9 | A, D |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Demonstration | 1,2,3,4,5,6,7,8 |
| 2 | The preparations of cachet | 1,2,3,4,5,6,7,8 |
| 3 | The preparation of hard gelatin capsules | 1,2,3,4,5,6,7,8 |
| 4 | Wet and dry granulation | 1,2,3,4,5,6,7,8 |
| 5 | The preparation of tablet by direct compression method | 1,2,3,4,5,6,7,8 |
| 6 | The preparation of tablet by wet granulation method | 1,2,3,4,5,6,7,8 |
| 7 | The preparation of tablet by wet granulation method | 1,2,3,4,5,6,7,8 |
| 8 | The preparation of effervescent tablets | 1,2,3,4,5,6,7,8 |
| 9 | The coating of tablets by Wurster Apparatus | 1,2,3,4,5,6,7,8 |
| 10 | The preparation of dragee | 1,2,3,4,5,6,7,8 |
| 11 | The quality control of granule | 1,2,3,4,5,6,7,8 |
| 12 | The quality control of tablets | 1,2,3,4,5,6,7,8 |
| 13 | Accerelated stability test | 1,2,3,4,5,6,7,8 |
| 14 | Make-up | 1,2,3,4,5,6,7,8 |
| Resources |
| 1-Lecture notes, powerpoint presentations, relevant web pages will be given to students. 2) Alpmen G, Altınkurt T, Bergişadi N, Topaloğlu Y, Tunçel T, Araman A, Yener G, Özsoy Y,‘Farmasötik Teknoloji ve Kozmetoloji Laboratuvar Kitabı’ AB Ofset, İstanbul, 2000.Bozkır A, 3) Karataş A, Hasçiçek C, Canefe K, Kılıçarslan M, Tarımcı N, Yüksel N, Gönül N,Özdemir N, Baykara T, Kılınç-Şen T, Çomoğlu T, ‘Farmasötik Teknoloji Deneysel Uygulamalar Kitabı’ Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 4) Türk Farmakopesi (TF 2017) 5) Tıbbi ve Kozmetik Formüller (Prof. Dr. Kasım Cemal Güven) 2020 6) Martindale-the Extra Pharmacopoeia 7) USP United States Pharmacopoeia 32 8) European Pharmacopoeia 10 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 10 | 1 | 10 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 10 | 1 | 10 | |||
| Midterm Exam | 1 | 8 | 8 | |||
| General Exam | 1 | 16 | 16 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 86 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(86/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL TECHNOLOGY LAB. IV | PHA4214879 | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program | ( B ) Pazartesi 13:30-14:15 ( B ) Pazartesi 14:30-15:15 ( B ) Pazartesi 15:30-16:15 ( A ) Pazartesi 10:00-10:45 ( A ) Pazartesi 11:00-11:45 ( A ) Pazartesi 12:00-12:45 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma Julide AKBUĞA |
| Name of Lecturer(s) | Prof.Dr. Fatma Julide AKBUĞA |
| Assistant(s) | |
| Aim | To be intended to enable students to have practical skills the preparations and quality controls of solid dosage forms, stability tests and reaction kinetics. |
| Course Content | This course contains; Demonstration,The preparations of cachet,The preparation of hard gelatin capsules,Wet and dry granulation,The preparation of tablet by direct compression method,The preparation of tablet by wet granulation method,The preparation of tablet by wet granulation method,The preparation of effervescent tablets,The coating of tablets by Wurster Apparatus,The preparation of dragee,The quality control of granule,The quality control of tablets,Accerelated stability test,Make-up. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the and of this course, the students; | ||
| 1. prepare powder formulations, capsule and tablet. | 10, 12, 17, 19, 9 | A, D |
| 1. will be defined powder formulations, capsule and tablet. | 10, 12, 17, 19, 9 | A, D |
| 1.2. recognize the excipients of tablet. | 10, 12, 17, 19, 9 | A, D |
| 1.3. Recognize excipients used in the preparation of solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 2. will be evaluated the coating methods of tablet-solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 2.1. interpret the devices used the coating of solid dosage forms | 10, 12, 17, 19, 9 | A, D |
| 2.2. categorize the coating of solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 3. will be assessed the quality control of the solid dosage forms. | 10, 12, 17, 19, 9 | A, D |
| 3.1. interpret the controls of granule. | 10, 12, 17, 19, 9 | A, D |
| 3.2. design the quality control of tablets. | 10, 12, 17, 19, 9 | A, D |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Demonstration | 1,2,3,4,5,6,7,8 |
| 2 | The preparations of cachet | 1,2,3,4,5,6,7,8 |
| 3 | The preparation of hard gelatin capsules | 1,2,3,4,5,6,7,8 |
| 4 | Wet and dry granulation | 1,2,3,4,5,6,7,8 |
| 5 | The preparation of tablet by direct compression method | 1,2,3,4,5,6,7,8 |
| 6 | The preparation of tablet by wet granulation method | 1,2,3,4,5,6,7,8 |
| 7 | The preparation of tablet by wet granulation method | 1,2,3,4,5,6,7,8 |
| 8 | The preparation of effervescent tablets | 1,2,3,4,5,6,7,8 |
| 9 | The coating of tablets by Wurster Apparatus | 1,2,3,4,5,6,7,8 |
| 10 | The preparation of dragee | 1,2,3,4,5,6,7,8 |
| 11 | The quality control of granule | 1,2,3,4,5,6,7,8 |
| 12 | The quality control of tablets | 1,2,3,4,5,6,7,8 |
| 13 | Accerelated stability test | 1,2,3,4,5,6,7,8 |
| 14 | Make-up | 1,2,3,4,5,6,7,8 |
| Resources |
| 1-Lecture notes, powerpoint presentations, relevant web pages will be given to students. 2) Alpmen G, Altınkurt T, Bergişadi N, Topaloğlu Y, Tunçel T, Araman A, Yener G, Özsoy Y,‘Farmasötik Teknoloji ve Kozmetoloji Laboratuvar Kitabı’ AB Ofset, İstanbul, 2000.Bozkır A, 3) Karataş A, Hasçiçek C, Canefe K, Kılıçarslan M, Tarımcı N, Yüksel N, Gönül N,Özdemir N, Baykara T, Kılınç-Şen T, Çomoğlu T, ‘Farmasötik Teknoloji Deneysel Uygulamalar Kitabı’ Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 4) Türk Farmakopesi (TF 2017) 5) Tıbbi ve Kozmetik Formüller (Prof. Dr. Kasım Cemal Güven) 2020 6) Martindale-the Extra Pharmacopoeia 7) USP United States Pharmacopoeia 32 8) European Pharmacopoeia 10 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |