Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL TECHNOLOGY LAB. II | PHA3214158 | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program | ( B ) Salı 13:30-14:15 ( B ) Salı 14:30-15:15 ( B ) Salı 15:30-16:15 ( A ) Cuma 14:30-15:15 ( A ) Cuma 15:30-16:15 ( A ) Cuma 16:30-17:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma Julide AKBUĞA |
| Name of Lecturer(s) | Prof.Dr. Fatma Julide AKBUĞA |
| Assistant(s) | |
| Aim | To be performed the design of semi-solid dosage forms (ointment, path, suppository, gel etc.) and two-phase systems formulations, preparations and controls. |
| Course Content | This course contains; Demonstration,Suspensions and their preparations,Quality control in suspensions, determination of distribution and sedimentation volume, particle size distribution in suspensions,Emulsion preparation and HLB values calculation,Determination of emulsion types,Liniments,Ointments (the preparation of simple and hydrophilic ointment),Ointment with active ingredients and gel preparations,Path preparations,Cold cream, stearate cream,Suppository preparations,Dissolubility test in suppositories,Ovule preparations,Ovule preparations. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course the students; | ||
| 1. will be planned two-phase systems | 10, 17, 9 | A |
| 1.1. prepare the suspension formulations. | 10, 12, 17, 19, 9 | A, D |
| 1.2. perform the determination of distribution and sedimentation volume, particle size distribution in suspensions. | 10, 12, 17, 19, 9 | A, D |
| 1.3. prepare the emulsion formulations. | 10, 12, 17, 19, 9 | A, D |
| 1.4. calculate the determination of viscosity and HLB values. | 10, 12, 17, 19 | A |
| 2. will be prepared semi-solid system formulations. | 10, 12, 17, 19, 9 | A, D |
| 2.1. plan semi-solid formulations including ointment, path, gel, cold cream, stearate cream. | 10, 12, 17, 19, 9 | A, D |
| 2.2. define the excipients using in semi-solid formulations. | 10, 12, 17, 19, 9 | A, D |
| 2.3. prepare suppository and ovule. | 10, 12, 17, 19, 9 | A, D |
| 2.4. evaluate the base ingredients using in preparation of suppository and ovule formulations. | 10, 12, 17, 19, 9 | A |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Demonstration | 1,2,3,4,5,6,7,8 |
| 2 | Suspensions and their preparations | 1,2,3,4,5,6,7,8 |
| 3 | Quality control in suspensions, determination of distribution and sedimentation volume, particle size distribution in suspensions | 1,2,3,4,5,6,7,8 |
| 4 | Emulsion preparation and HLB values calculation | 1,2,3,4,5,6,7,8 |
| 5 | Determination of emulsion types | 1,2,3,4,5,6,7,8 |
| 6 | Liniments | 1,2,3,4,5,6,7,8 |
| 7 | Ointments (the preparation of simple and hydrophilic ointment) | 1,2,3,4,5,6,7,8 |
| 8 | Ointment with active ingredients and gel preparations | 1,2,3,4,5,6,7,8 |
| 9 | Path preparations | 1,2,3,4,5,6,7,8 |
| 10 | Cold cream, stearate cream | 1,2,3,4,5,6,7,8 |
| 11 | Suppository preparations | 1,2,3,4,5,6,7,8 |
| 12 | Dissolubility test in suppositories | 1,2,3,4,5,6,7,8 |
| 13 | Ovule preparations | 1,2,3,4,5,6,7,8 |
| 14 | Ovule preparations | 1,2,3,4,5,6,7,8 |
| Resources |
| 1-Lecture notes, Powerpoint presentations, Relevant web pages will be given to students.2) Alpmen G, Altınkurt T, Bergişadi N, Topaloğlu Y, Tunçel T, Araman A, Yener G, Özsoy Y,‘Farmasötik Teknoloji ve Kozmetoloji Laboratuvar Kitabı’ AB Ofset, İstanbul, 2000.Bozkır A, 3) Karataş A, Hasçiçek C, Canefe K, Kılıçarslan M, Tarımcı N, Yüksel N, Gönül N,Özdemir N, Baykara T, Kılınç-Şen T, Çomoğlu T, ‘Farmasötik Teknoloji Deneysel Uygulamalar Kitabı’ Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 4) Türk Farmakopesi (TF 2017) 5) Tıbbi ve Kozmetik Formüller (Prof. Dr. Kasım Cemal Güven) 2020 6) Martindale-the Extra Pharmacopoeia 7) USP United States Pharmacopoeia 32 8) European Pharmacopoeia 10 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 10 | 1 | 10 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 10 | 1 | 10 | |||
| Midterm Exam | 1 | 8 | 8 | |||
| General Exam | 1 | 16 | 16 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 86 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(86/30) | 3 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL TECHNOLOGY LAB. II | PHA3214158 | Spring Semester | 0+3 | 1,5 | 3 |
| Course Program | ( B ) Salı 13:30-14:15 ( B ) Salı 14:30-15:15 ( B ) Salı 15:30-16:15 ( A ) Cuma 14:30-15:15 ( A ) Cuma 15:30-16:15 ( A ) Cuma 16:30-17:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma Julide AKBUĞA |
| Name of Lecturer(s) | Prof.Dr. Fatma Julide AKBUĞA |
| Assistant(s) | |
| Aim | To be performed the design of semi-solid dosage forms (ointment, path, suppository, gel etc.) and two-phase systems formulations, preparations and controls. |
| Course Content | This course contains; Demonstration,Suspensions and their preparations,Quality control in suspensions, determination of distribution and sedimentation volume, particle size distribution in suspensions,Emulsion preparation and HLB values calculation,Determination of emulsion types,Liniments,Ointments (the preparation of simple and hydrophilic ointment),Ointment with active ingredients and gel preparations,Path preparations,Cold cream, stearate cream,Suppository preparations,Dissolubility test in suppositories,Ovule preparations,Ovule preparations. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| At the end of this course the students; | ||
| 1. will be planned two-phase systems | 10, 17, 9 | A |
| 1.1. prepare the suspension formulations. | 10, 12, 17, 19, 9 | A, D |
| 1.2. perform the determination of distribution and sedimentation volume, particle size distribution in suspensions. | 10, 12, 17, 19, 9 | A, D |
| 1.3. prepare the emulsion formulations. | 10, 12, 17, 19, 9 | A, D |
| 1.4. calculate the determination of viscosity and HLB values. | 10, 12, 17, 19 | A |
| 2. will be prepared semi-solid system formulations. | 10, 12, 17, 19, 9 | A, D |
| 2.1. plan semi-solid formulations including ointment, path, gel, cold cream, stearate cream. | 10, 12, 17, 19, 9 | A, D |
| 2.2. define the excipients using in semi-solid formulations. | 10, 12, 17, 19, 9 | A, D |
| 2.3. prepare suppository and ovule. | 10, 12, 17, 19, 9 | A, D |
| 2.4. evaluate the base ingredients using in preparation of suppository and ovule formulations. | 10, 12, 17, 19, 9 | A |
| Teaching Methods: | 10: Discussion Method, 12: Problem Solving Method, 17: Experimental Technique, 19: Brainstorming Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam, D: Oral Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | Demonstration | 1,2,3,4,5,6,7,8 |
| 2 | Suspensions and their preparations | 1,2,3,4,5,6,7,8 |
| 3 | Quality control in suspensions, determination of distribution and sedimentation volume, particle size distribution in suspensions | 1,2,3,4,5,6,7,8 |
| 4 | Emulsion preparation and HLB values calculation | 1,2,3,4,5,6,7,8 |
| 5 | Determination of emulsion types | 1,2,3,4,5,6,7,8 |
| 6 | Liniments | 1,2,3,4,5,6,7,8 |
| 7 | Ointments (the preparation of simple and hydrophilic ointment) | 1,2,3,4,5,6,7,8 |
| 8 | Ointment with active ingredients and gel preparations | 1,2,3,4,5,6,7,8 |
| 9 | Path preparations | 1,2,3,4,5,6,7,8 |
| 10 | Cold cream, stearate cream | 1,2,3,4,5,6,7,8 |
| 11 | Suppository preparations | 1,2,3,4,5,6,7,8 |
| 12 | Dissolubility test in suppositories | 1,2,3,4,5,6,7,8 |
| 13 | Ovule preparations | 1,2,3,4,5,6,7,8 |
| 14 | Ovule preparations | 1,2,3,4,5,6,7,8 |
| Resources |
| 1-Lecture notes, Powerpoint presentations, Relevant web pages will be given to students.2) Alpmen G, Altınkurt T, Bergişadi N, Topaloğlu Y, Tunçel T, Araman A, Yener G, Özsoy Y,‘Farmasötik Teknoloji ve Kozmetoloji Laboratuvar Kitabı’ AB Ofset, İstanbul, 2000.Bozkır A, 3) Karataş A, Hasçiçek C, Canefe K, Kılıçarslan M, Tarımcı N, Yüksel N, Gönül N,Özdemir N, Baykara T, Kılınç-Şen T, Çomoğlu T, ‘Farmasötik Teknoloji Deneysel Uygulamalar Kitabı’ Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 4) Türk Farmakopesi (TF 2017) 5) Tıbbi ve Kozmetik Formüller (Prof. Dr. Kasım Cemal Güven) 2020 6) Martindale-the Extra Pharmacopoeia 7) USP United States Pharmacopoeia 32 8) European Pharmacopoeia 10 |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | ||||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 60 | |
| Rate of Final Exam to Success | 40 | |
| Total | 100 | |