Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL TECHNOLOGY I | PHA3114149 | Fall Semester | 3+0 | 3 | 5 |
| Course Program | Çarşamba 14:30-15:15 Çarşamba 15:30-16:15 Çarşamba 16:30-17:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma Julide AKBUĞA |
| Name of Lecturer(s) | Prof.Dr. Fatma Julide AKBUĞA, Assist.Prof. Burcu ÜNER |
| Assistant(s) | |
| Aim | To inform the students about the basic knowledge of pharmaceutical technology, parmaceutical water, solutions and dissolution. |
| Course Content | This course contains; The historical development of the drug, international pharmaceutical organizations,Pharmaceutical calculations (prescription and dose calculation),The basic process on pharmaceutical manufacturing,The basic process on pharmaceutical manufacturing,Colligative properties,Extraction and the pharmaceutical preparations prepared by extraction,Drug delivery systems and the routes of administration,Drug delivery systems and the routes of administration,Preformulation, pharmaceutical excipients and the stability of dosage forms,Pharmaceutical water,Pharmaceutical water,Solutions,Solutions,Solubility and the factors affecting solubility. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. will be assessed the basic concept on pharmaceutical technology. | 16, 9 | A |
| 1.1. Will be used pharmaceutical knowledge resources (pharmacopeia, codex ect.) | 16, 9 | A |
| 1.2. Use prescription formulations and dose calculations. | 16, 9 | A |
| 1.3. analyse the process of the pharmaceutical calculation. | 16, 9 | A |
| 2. Will be distinguished the basic process of pahmaceutical technology. | 16, 9 | A |
| 2.1. tell the elaboration of milling, mixing, sieving and filtering process. | 16, 9 | A |
| 2.3. Recognize the devices used in the basic process of pharmaceutical technology. | 16, 9 | A |
| 3. will be prepared the pharmaceutical preparations prepared by extraction. | 16, 9 | A |
| 3.1. define the distilation concept and the methods of distilation. | 16, 9 | A |
| 3.2. categorize the extraction types. | 16, 9 | A |
| 3.3. prepare a variety of the extraction preparations. | 16, 9 | A |
| 4. will be defined preformulation, pharmaceutical excipients and the stability of dosage forms. | 16, 9 | A |
| 4.1. interpret the parameter of the preformulation studies. | 16, 9 | A |
| 4.2. categorize the pharmaceutical excipients. | 16, 9 | A |
| 4.3. Evaluate the properties of the pharmaceutical excipients. | 16, 9 | A |
| 4.4. assess the stability and safety of the pharmaceutical excipients. | 16, 9 | A |
| 5. will be defined pharmaceutical water and the methods of the water purificiation. | 16, 9 | A |
| 5.1. debate the methods of the water purificiation. | 16, 9 | A |
| 5.2. interpret the controls on pharmaceutical water. | 16, 9 | A |
| 6. will be designed the solution-type dosage forms. | 16, 9 | A |
| 6.1. list the formulation ingredients of the solutions. | 16, 9 | A |
| 6.2. debate the quality controls of the solution-type dosage forms. | 16, 9 | A |
| 6.3. design the methods of the solution preparation. | 16, 9 | A |
| 6.4. define the concept of solubility, dissolution rate. | 16, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | The historical development of the drug, international pharmaceutical organizations | 1,2,3 |
| 2 | Pharmaceutical calculations (prescription and dose calculation) | 1,2,3 |
| 3 | The basic process on pharmaceutical manufacturing | 1,2,3 |
| 4 | The basic process on pharmaceutical manufacturing | 1,2,3 |
| 5 | Colligative properties | 1,2,3 |
| 6 | Extraction and the pharmaceutical preparations prepared by extraction | 1,2,3 |
| 7 | Drug delivery systems and the routes of administration | 1,2,3 |
| 8 | Drug delivery systems and the routes of administration | 1,2,3 |
| 9 | Preformulation, pharmaceutical excipients and the stability of dosage forms | 1,2,3 |
| 10 | Pharmaceutical water | 1,2,3 |
| 11 | Pharmaceutical water | 1,2,3 |
| 12 | Solutions | 1,2,3 |
| 13 | Solutions | 1,2,3 |
| 14 | Solubility and the factors affecting solubility | 1,2,3 |
| Resources |
| 1-Lecture notes, Powerpoint presentations, Relevant web pages will be given to students.2-Acartürk F, Ağabeyoğlu İ, Çelebi D, Değim T, Değim Z, Doğanay T, Taka S, Tırnaksız F. Modern Farmasötik Teknoloji. Türk Eczacılar Birliği Yayını. 2.baskı. Ankara.2008. 3-Zırh Gürsoy A (ed.). Farmasötik Teknoloji –Temel Konular ve Dozaj Şekilleri-. Kontrollü Salım Sistemleri Derneği Yayını. 2.baskı. İstanbul. 2012. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |
| ECTS / Workload Table | ||||||
| Activities | Number of | Duration(Hour) | Total Workload(Hour) | |||
| Course Hours | 14 | 3 | 42 | |||
| Guided Problem Solving | 0 | 0 | 0 | |||
| Resolution of Homework Problems and Submission as a Report | 2 | 5 | 10 | |||
| Term Project | 0 | 0 | 0 | |||
| Presentation of Project / Seminar | 0 | 0 | 0 | |||
| Quiz | 0 | 0 | 0 | |||
| Midterm Exam | 1 | 30 | 30 | |||
| General Exam | 1 | 60 | 60 | |||
| Performance Task, Maintenance Plan | 0 | 0 | 0 | |||
| Total Workload(Hour) | 142 | |||||
| Dersin AKTS Kredisi = Toplam İş Yükü (Saat)/30*=(142/30) | 5 | |||||
| ECTS of the course: 30 hours of work is counted as 1 ECTS credit. | ||||||
Detail Informations of the Course
Course Description
| Course | Code | Semester | T+P (Hour) | Credit | ECTS |
|---|---|---|---|---|---|
| PHARMACEUTICAL TECHNOLOGY I | PHA3114149 | Fall Semester | 3+0 | 3 | 5 |
| Course Program | Çarşamba 14:30-15:15 Çarşamba 15:30-16:15 Çarşamba 16:30-17:15 |
| Prerequisites Courses | |
| Recommended Elective Courses |
| Language of Course | English |
| Course Level | First Cycle (Bachelor's Degree) |
| Course Type | Required |
| Course Coordinator | Prof.Dr. Fatma Julide AKBUĞA |
| Name of Lecturer(s) | Prof.Dr. Fatma Julide AKBUĞA, Assist.Prof. Burcu ÜNER |
| Assistant(s) | |
| Aim | To inform the students about the basic knowledge of pharmaceutical technology, parmaceutical water, solutions and dissolution. |
| Course Content | This course contains; The historical development of the drug, international pharmaceutical organizations,Pharmaceutical calculations (prescription and dose calculation),The basic process on pharmaceutical manufacturing,The basic process on pharmaceutical manufacturing,Colligative properties,Extraction and the pharmaceutical preparations prepared by extraction,Drug delivery systems and the routes of administration,Drug delivery systems and the routes of administration,Preformulation, pharmaceutical excipients and the stability of dosage forms,Pharmaceutical water,Pharmaceutical water,Solutions,Solutions,Solubility and the factors affecting solubility. |
| Dersin Öğrenme Kazanımları | Teaching Methods | Assessment Methods |
| 1. will be assessed the basic concept on pharmaceutical technology. | 16, 9 | A |
| 1.1. Will be used pharmaceutical knowledge resources (pharmacopeia, codex ect.) | 16, 9 | A |
| 1.2. Use prescription formulations and dose calculations. | 16, 9 | A |
| 1.3. analyse the process of the pharmaceutical calculation. | 16, 9 | A |
| 2. Will be distinguished the basic process of pahmaceutical technology. | 16, 9 | A |
| 2.1. tell the elaboration of milling, mixing, sieving and filtering process. | 16, 9 | A |
| 2.3. Recognize the devices used in the basic process of pharmaceutical technology. | 16, 9 | A |
| 3. will be prepared the pharmaceutical preparations prepared by extraction. | 16, 9 | A |
| 3.1. define the distilation concept and the methods of distilation. | 16, 9 | A |
| 3.2. categorize the extraction types. | 16, 9 | A |
| 3.3. prepare a variety of the extraction preparations. | 16, 9 | A |
| 4. will be defined preformulation, pharmaceutical excipients and the stability of dosage forms. | 16, 9 | A |
| 4.1. interpret the parameter of the preformulation studies. | 16, 9 | A |
| 4.2. categorize the pharmaceutical excipients. | 16, 9 | A |
| 4.3. Evaluate the properties of the pharmaceutical excipients. | 16, 9 | A |
| 4.4. assess the stability and safety of the pharmaceutical excipients. | 16, 9 | A |
| 5. will be defined pharmaceutical water and the methods of the water purificiation. | 16, 9 | A |
| 5.1. debate the methods of the water purificiation. | 16, 9 | A |
| 5.2. interpret the controls on pharmaceutical water. | 16, 9 | A |
| 6. will be designed the solution-type dosage forms. | 16, 9 | A |
| 6.1. list the formulation ingredients of the solutions. | 16, 9 | A |
| 6.2. debate the quality controls of the solution-type dosage forms. | 16, 9 | A |
| 6.3. design the methods of the solution preparation. | 16, 9 | A |
| 6.4. define the concept of solubility, dissolution rate. | 16, 9 | A |
| Teaching Methods: | 16: Question - Answer Technique, 9: Lecture Method |
| Assessment Methods: | A: Traditional Written Exam |
Course Outline
| Order | Subjects | Preliminary Work |
|---|---|---|
| 1 | The historical development of the drug, international pharmaceutical organizations | 1,2,3 |
| 2 | Pharmaceutical calculations (prescription and dose calculation) | 1,2,3 |
| 3 | The basic process on pharmaceutical manufacturing | 1,2,3 |
| 4 | The basic process on pharmaceutical manufacturing | 1,2,3 |
| 5 | Colligative properties | 1,2,3 |
| 6 | Extraction and the pharmaceutical preparations prepared by extraction | 1,2,3 |
| 7 | Drug delivery systems and the routes of administration | 1,2,3 |
| 8 | Drug delivery systems and the routes of administration | 1,2,3 |
| 9 | Preformulation, pharmaceutical excipients and the stability of dosage forms | 1,2,3 |
| 10 | Pharmaceutical water | 1,2,3 |
| 11 | Pharmaceutical water | 1,2,3 |
| 12 | Solutions | 1,2,3 |
| 13 | Solutions | 1,2,3 |
| 14 | Solubility and the factors affecting solubility | 1,2,3 |
| Resources |
| 1-Lecture notes, Powerpoint presentations, Relevant web pages will be given to students.2-Acartürk F, Ağabeyoğlu İ, Çelebi D, Değim T, Değim Z, Doğanay T, Taka S, Tırnaksız F. Modern Farmasötik Teknoloji. Türk Eczacılar Birliği Yayını. 2.baskı. Ankara.2008. 3-Zırh Gürsoy A (ed.). Farmasötik Teknoloji –Temel Konular ve Dozaj Şekilleri-. Kontrollü Salım Sistemleri Derneği Yayını. 2.baskı. İstanbul. 2012. |
Course Contribution to Program Qualifications
| Course Contribution to Program Qualifications | |||||||
| No | Program Qualification | Contribution Level | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | PQ-1. Skilfully use information technology to access, follow, evaluate and apply current knowledge in the field of Pharmaceutical Sciences. | X | |||||
| 2 | PQ-2. Have advanced knowledge in APIs and DPs. | X | |||||
| 3 | PQ-3. Collaborate with the experts for collection, interpretation, application and declaration of data in Pharmaceutical Sciences field. | X | |||||
| 4 | PQ-4. Provide best patient counseling services and medication therapy management using his/her knowledge and pharmaceutical information systems to improve the quality of life and safety of patient. | X | |||||
| 5 | PQ-5. Capable of organizing and administering a drugstore as per responsibilities prescribed under the Pharmacy Law, using skills, knowledge and advanced technology systems. | X | |||||
| 6 | PQ-6. Skilfully use computer programs and advanced technology related to the Pharmaceutical Sciences. | X | |||||
| 7 | PQ-7. Provide solutions to the professional issues using scientific knowledge and data. | X | |||||
| 8 | PQ-8. Perform identification, quality control and standardization of the drug products. | X | |||||
| 9 | PQ-9. Prepare and implement developmental plans for his/her subordinates, frequently evaluate their progress and make necessary adjustments. | X | |||||
| 10 | PQ-10. Capable of conducting independent studies with his/her advanced knowledge in pharmaceutical sciences, takes responsibilities in professional organizations and efficiently collaborates with the members of his/her own organization as well as other organizations. | X | |||||
| 11 | PQ-11. Clearly show signs of adoption of life-long learning and openness to further development. | X | |||||
| 12 | PQ-12. Critically evaluate their knowledge in pharmaceutical sciences. | X | |||||
| 13 | PQ-13. Closely follow and evaluate the national and international professional developments. | X | |||||
| 14 | PQ-14. Record and document all professional activities and applications. | X | |||||
| 15 | PQ-15. Communicate all necessary information about medicines to patient, medical personnel and public. | X | |||||
| 16 | PQ-16. Proficient in English to communicate and follow current knowledge in pharmaceutical sciences. | X | |||||
| 17 | PQ-17. Inform officials and organizations about the issues with the quality assurance of pharmaceutical products. | X | |||||
| 18 | PQ-18. Actively involve in the preparation of APIs, every stage of the formulation and production of DPs. | X | |||||
| 19 | PQ-19. Knowledgable in the regulatory rules of new drug application, data protection and patent issues and understand their interrelationship. | X | |||||
| 20 | PQ-20. Have awareness of his/her duties, rights and responsibilities and act based on Pharmacy Law and high professional ethical standards. | X | |||||
| 21 | PQ-21. Familiar with and actively pursue the personal and public health, environmental, and work safety issues. | X | |||||
Assessment Methods
| Contribution Level | Absolute Evaluation | |
| Rate of Midterm Exam to Success | 40 | |
| Rate of Final Exam to Success | 60 | |
| Total | 100 | |